المؤلفون: Faggiano, Andrea, Gherbesi, Elisa, Carugo, Stefano, Brusamolino, Matteo, Cozac, Dan Alexandru, Cozza, Elena, Savo, Maria Teresa, Cannata, Francesco, Guglielmo, Marco, La Mura, Lucia, Fazzari, Fabio, Carrabba, Nazario, Conte, Edoardo, Mushtaq, Saima, Baggiano, Andrea, Guaricci, Andrea I, Pedrinelli, Roberto, Indolfi, Ciro, Sinagra, Gianfranco, Perrone Filardi, Pasquale, Pergola, Valeria, Pontone, Gianluca

المصدر: European Heart Journal - Cardiovascular Imaging ; ISSN 2047-2404 2047-2412

الاتاحة: https://doi.org/10.1093/ehjci/jeae324
https://academic.oup.com/ehjcimaging/advance-article-pdf/doi/10.1093/ehjci/jeae324/61398296/jeae324.pdf

المؤلفون: Paolisso, Pasquale, Bergamaschi, Luca, Angeli, Francesco, Belmonte, Marta, Foa, Alberto, Canton, Lisa, Fedele, Damiano, Armillotta, Matteo, Sansonetti, Angelo, Bodega, Francesca, Amicone, Sara, Suma, Nicole, Gallinoro, Emanuele, Attinà, Domenico, Niro, Fabio, Rucci, Paola, Gherbesi, Elisa, Carugo, Stefano, Musthaq, Saima, Baggiano, Andrea, Pavon, Anna Giulia, Guglielmo, Marco, Conte, Edoardo, Andreini, Daniele, Pontone, Gianluca, Lovato, Luigi, Pizzi, Carmine

المساهمون: Paolisso, Pasquale, Bergamaschi, Luca, Angeli, Francesco, Belmonte, Marta, Foa, Alberto, Canton, Lisa, Fedele, Damiano, Armillotta, Matteo, Sansonetti, Angelo, Bodega, Francesca, Amicone, Sara, Suma, Nicole, Gallinoro, Emanuele, Attinà, Domenico, Niro, Fabio, Rucci, Paola, Gherbesi, Elisa, Carugo, Stefano, Musthaq, Saima, Baggiano, Andrea, Pavon, Anna Giulia, Guglielmo, Marco, Conte, Edoardo, Andreini, Daniele, Pontone, Gianluca, Lovato, Luigi, Pizzi, Carmine

مصطلحات موضوعية: cardiac magnetic resonance (CMR), cardiac masse, echocardiography, prognosis

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/38502734; info:eu-repo/semantics/altIdentifier/wos/WOS:001187204600011; volume:17; issue:3; firstpage:185; lastpage:197; numberofpages:13; journal:CIRCULATION. CARDIOVASCULAR IMAGING; https://hdl.handle.net/11585/966857; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85188351376

الاتاحة: https://hdl.handle.net/11585/966857
https://doi.org/10.1161/circimaging.123.016115
https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.123.016115

المؤلفون: Vizzuso, Sara, Torto, Alberico Del, Fiore, Giulia, Carugo, Stefano, Zuccotti, Gianvincenzo, Verduci, Elvira

المساهمون: S. Vizzuso, A.D. Torto, G. Fiore, S. Carugo, G. Zuccotti, E. Verduci

مصطلحات موضوعية: Cardiovascular risk, Left ventricular hypertrophy, Left ventricular mass index, Pediatric obesity, Tri-ponderal mass index, Settore MEDS-20/A - Pediatria generale e specialistica

Relation: info:eu-repo/semantics/altIdentifier/pmid/38637874; info:eu-repo/semantics/altIdentifier/wos/WOS:001205109800001; volume:50; issue:1; firstpage:1; lastpage:10; numberofpages:10; journal:THE ITALIAN JOURNAL OF PEDIATRICS; https://hdl.handle.net/2434/1124295

الاتاحة: https://hdl.handle.net/2434/1124295
https://doi.org/10.1186/s13052-024-01634-9

المؤلفون: Faggiano, Andrea, Gherbesi, Elisa, Giordano, Chiara, Gamberini, Giacomo, Vicenzi, Marco, Cuspidi, Cesare, Carugo, Stefano, Cipolla, Carlo M, Cardinale, Daniela M

المساهمون: A. Faggiano, E. Gherbesi, C. Giordano, G. Gamberini, M. Vicenzi, C. Cuspidi, S. Carugo, C.M. Cipolla, D.M. Cardinale

مصطلحات موضوعية: anthracycline chemotherapy, right ventricular dysfunction, breast cancer, strain echocardiography, cardiotoxicity, Settore MEDS-07/B - Malattie dell'apparato cardiovascolare

Relation: info:eu-repo/semantics/altIdentifier/pmid/39594841; info:eu-repo/semantics/altIdentifier/wos/WOS:001364894900001; volume:16; issue:22; firstpage:1; lastpage:19; numberofpages:19; journal:CANCERS; https://hdl.handle.net/2434/1121116

الاتاحة: https://hdl.handle.net/2434/1121116
https://doi.org/10.3390/cancers16223883

المؤلفون: Corti, Carla Giuseppina, Nespoli, Luisa Federica, Campari, Alessandro, Gnan, Eleonora, Ruscica, Massimiliano, Carugo, Stefano

المساهمون: C.G. Corti, L.F. Nespoli, A. Campari, E. Gnan, M. Ruscica, S. Carugo

مصطلحات موضوعية: Settore MEDS-02/A - Patologia generale

Relation: info:eu-repo/semantics/altIdentifier/pmid/39649278; info:eu-repo/semantics/altIdentifier/wos/WOS:001365820600029; volume:20; issue:5; firstpage:1695; lastpage:1700; numberofpages:6; journal:ARCHIVES OF MEDICAL SCIENCE; https://hdl.handle.net/2434/1120022

الاتاحة: https://hdl.handle.net/2434/1120022
https://doi.org/10.5114/aoms/194435

المؤلفون: Carugo, Stefano, Vescini, Fabio, Giusti, Andrea, Mauro, Giulia Letizia, Tafaro, Laura, Festuccia, Francescaromana, Muraca, Lucia, Menè, Paolo, Rossini, Maurizio

المساهمون: S. Carugo, F. Vescini, A. Giusti, G.L. Mauro, L. Tafaro, F. Festuccia, L. Muraca, P. Menè, M. Rossini

مصطلحات موضوعية: Cardiovascular risk, Fragility fracture prevention, Nephrolithiasis risk, Osteoporosi, calcium, Vitamin D, Settore MEDS-07/B - Malattie dell'apparato cardiovascolare

Relation: info:eu-repo/semantics/altIdentifier/pmid/39438361; info:eu-repo/semantics/altIdentifier/wos/WOS:001340332200001; volume:19; issue:1; firstpage:1; lastpage:10; numberofpages:10; journal:ARCHIVES OF OSTEOPOROSIS; https://hdl.handle.net/2434/1118789

الاتاحة: https://hdl.handle.net/2434/1118789
https://doi.org/10.1007/s11657-024-01451-x

المؤلفون: Xie, Sining, Galimberti, Federica, Olmastroni, Elena, Lüscher, Thomas F, Carugo, Stefano, Catapano, Alberico L, Casula, Manuela, META-LIPID Group

المصدر: Xie, Sining; Galimberti, Federica; Olmastroni, Elena; Lüscher, Thomas F; Carugo, Stefano; Catapano, Alberico L; Casula, Manuela; META-LIPID Group (2024). Effect of lipid-lowering therapies on C-reactive protein levels: a comprehensive meta-analysis of randomized controlled trials. Cardiovascular Research, 120(4):333-344.

مصطلحات موضوعية: Center for Molecular Cardiology, 610 Medicine & health

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/262387/1/ZORA_cvae034.pdf; info:pmid/38373008; urn:issn:0008-6363

الاتاحة: https://www.zora.uzh.ch/id/eprint/262387/
https://www.zora.uzh.ch/id/eprint/262387/1/ZORA_cvae034.pdf
https://doi.org/10.1093/cvr/cvae034

المؤلفون: Sozzi, Fabiola, Iacuzio, Laura, Gnan, Eleonora, Levy, Franck, Eker, Armand, Canetta, Ciro, Ruscica, Massimiliano, Carugo, Stefano

المساهمون: F. Sozzi, L. Iacuzio, E. Gnan, F. Levy, A. Eker, C. Canetta, M. Ruscica, S. Carugo

مصطلحات موضوعية: Settore MED/11 - Malattie dell'Apparato Cardiovascolare, Settore MED/04 - Patologia Generale

Relation: info:eu-repo/semantics/altIdentifier/pmid/38973438; volume:82; issue:7-8; firstpage:806; lastpage:807; numberofpages:2; journal:KARDIOLOGIA POLSKA; https://hdl.handle.net/2434/1075388; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85203086914

الاتاحة: https://hdl.handle.net/2434/1075388
https://doi.org/10.33963/v.phj.101205

المؤلفون: Barbieri, Lucia, Tumminello, Gabriele, Pasero, Guido, Avallone, Carlo, D'Errico, Andrea, Mircoli, Luca, Colombo, Federico, Gobbi, Cecilia, Bellissimo, Nello Manuel, Ruscica, Massimiliano, Carugo, Stefano

المساهمون: L. Barbieri, G. Tumminello, G. Pasero, C. Avallone, A. D'Errico, L. Mircoli, F. Colombo, C. Gobbi, N.M. Bellissimo, M. Ruscica, S. Carugo

مصطلحات موضوعية: coronary artery computed tomography, invasive coronary angiography, chronic coronary syndromes, Settore MED/04 - Patologia Generale

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001311133600001; volume:14; issue:17; firstpage:1; lastpage:9; numberofpages:9; journal:DIAGNOSTICS; https://hdl.handle.net/2434/1093008

الاتاحة: https://hdl.handle.net/2434/1093008
https://doi.org/10.3390/diagnostics14171905

المؤلفون: Carandina, Angelica, Fanti, Giacomo, Carminati, Alessio, Baroni, Michele, Salafia, Greta, Arosio, Beatrice, Macchi, Chiara, Ruscica, Massimiliano, Vicenzi, Marco, Carugo, Stefano, Borghi, Francesca, Spinazzè, Andrea, Cavallo, Domenico Maria, Tobaldini, Eleonora, Montano, Nicola, Bonzini, Matteo

المساهمون: A. Carandina, G. Fanti, A. Carminati, M. Baroni, G. Salafia, B. Arosio, C. Macchi, M. Ruscica, M. Vicenzi, S. Carugo, F. Borghi, A. Spinazzè, D.M. Cavallo, E. Tobaldini, N. Montano, M. Bonzini

مصطلحات موضوعية: Cardiovascular autonomic control, Heart rate variability, Indoor air pollution, Inflammation, Sleep, Settore MED/09 - Medicina Interna

Relation: info:eu-repo/semantics/altIdentifier/pmid/39142457; info:eu-repo/semantics/altIdentifier/wos/WOS:001297708400001; volume:260; firstpage:1; lastpage:8; numberofpages:8; journal:ENVIRONMENTAL RESEARCH; https://hdl.handle.net/2434/1091508; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85201315386

الاتاحة: https://hdl.handle.net/2434/1091508
https://doi.org/10.1016/j.envres.2024.119783

المؤلفون: Barbieri, Lucia, Tumminello, Gabriele, Fichtner, Isabella, Corsini, Alberto, Santos, Raul D., Carugo, Stefano, Ruscica, Massimiliano

المساهمون: L. Barbieri, G. Tumminello, I. Fichtner, A. Corsini, R.D. Santo, S. Carugo, M. Ruscica

مصطلحات موضوعية: IVUS, Near-infrared spectroscopic, OCT, PCSK9 inhibitor, Plaque composition, Settore MED/04 - Patologia Generale, Settore MED/11 - Malattie dell'Apparato Cardiovascolare, Settore BIO/14 - Farmacologia

Relation: info:eu-repo/semantics/altIdentifier/pmid/39150672; info:eu-repo/semantics/altIdentifier/wos/WOS:001291927800001; firstpage:1; lastpage:14; numberofpages:14; journal:CURRENT ATHEROSCLEROSIS REPORTS; https://hdl.handle.net/2434/1087848

الاتاحة: https://hdl.handle.net/2434/1087848
https://doi.org/10.1007/s11883-024-01230-6

المؤلفون: Gallo, Antonio, Le Goff, Wilfried, Santos, Raul D., Fichtner, Isabella, Carugo, Stefano, Corsini, Alberto, Sirtori, Cesare, Ruscica, Massimiliano

المصدر: European Journal of Clinical Investigation ; ISSN 0014-2972 1365-2362

الاتاحة: http://dx.doi.org/10.1111/eci.14326
https://onlinelibrary.wiley.com/doi/pdf/10.1111/eci.14326

المؤلفون: Inciardi, Riccardo M., Vaduganathan, Muthiah, Lombardi, Carlo M., Gussago, Cristina, Agostoni, Piergiuseppe, Ameri, Pietro, Aspromonte, Nadia, Calò, Leonardo, Cameli, Matteo, Carluccio, Erberto, Carugo, Stefano, Cipriani, Manlio, De Caterina, Raffaele, De Ferrari, Gaetano M., Emdin, Michele, Fornaro, Alessandra, Guazzi, Marco, Iacoviello, Massimo, Imazio, Massimo, La Rovere, Maria Teresa, Leonardi, Sergio, Maccallini, Marta, Masarone, Daniele, Moschini, Luigi, Palazzuoli, Alberto, Patti, Giuseppe, Pedretti, Roberto F. E., Perrone Filardi, Pasquale, Piepoli, Massimo F., Potena, Luciano, Salzano, Andrea, Sciacqua, Angela, Senni, Michele, Sinagra, Gianfranco, Specchia, Claudia, Taddei, Stefano, Vizza, Dario, Savarese, Gianluigi, Rosano, Giuseppe, Volterrani, Maurizio, Metra, Marco

المساهمون: R.M. Inciardi, M. Vaduganathan, C.M. Lombardi, C. Gussago, P. Agostoni, P. Ameri, N. Aspromonte, L. Calò, M. Cameli, E. Carluccio, S. Carugo, M. Cipriani, R. De Caterina, G.M. De Ferrari, M. Emdin, A. Fornaro, M. Guazzi, M. Iacoviello, M. Imazio, M.T. La Rovere, S. Leonardi, M. Maccallini, D. Masarone, L. Moschini, A. Palazzuoli, G. Patti, R.F.E. Pedretti, P. Perrone Filardi, M.F. Piepoli, L. Potena, A. Salzano, A. Sciacqua, M. Senni, G. Sinagra, C. Specchia, S. Taddei, D. Vizza, G. Savarese, G. Rosano, M. Volterrani, M. Metra

مصطلحات موضوعية: Cardiovascular outcome, Guideline‐directed medical therapy, Heart failure, Settore MED/11 - Malattie dell'Apparato Cardiovascolare

Relation: info:eu-repo/semantics/altIdentifier/pmid/38923140; info:eu-repo/semantics/altIdentifier/wos/WOS:001253866900001; firstpage:1; lastpage:8; numberofpages:8; journal:EUROPEAN JOURNAL OF HEART FAILURE; https://hdl.handle.net/2434/1075048; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85196744916

الاتاحة: https://hdl.handle.net/2434/1075048
https://doi.org/10.1002/ejhf.3260

المؤلفون: Ruscica, Massimiliano, Bertoletti, Alessandra, Gobbi, Cecilia, Sirtori, Cesare R, Carugo, Stefano, Corsini, Alberto

المساهمون: M. Ruscica, A. Bertoletti, C. Gobbi, C.R. Sirtori, S. Carugo, A. Corsini

مصطلحات موضوعية: Statin, Ezetimibe, Bempedoic acid, PCSK9, Inclisiran, Settore MED/04 - Patologia Generale, Settore MED/11 - Malattie dell'Apparato Cardiovascolare, Settore BIO/14 - Farmacologia

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001203460200001; volume:26; issue:Supplement 1; firstpage:i56; lastpage:i59; numberofpages:4; journal:EUROPEAN HEART JOURNAL SUPPLEMENTS; https://hdl.handle.net/2434/1056088; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85190898115

الاتاحة: https://hdl.handle.net/2434/1056088
https://doi.org/10.1093/eurheartjsupp/suae007

المؤلفون: Rizzuto, Alessandra Stefania, Gelpi, Guido, Mangini, Andrea, Carugo, Stefano, Ruscica, Massimiliano, Macchi, Chiara

المساهمون: A.S. Rizzuto, G. Gelpi, A. Mangini, S. Carugo, M. Ruscica, C. Macchi

مصطلحات موضوعية: Cardiovascular medicine, Human metabolism, Physiology, Settore MED/11 - Malattie dell'Apparato Cardiovascolare, Settore MED/04 - Patologia Generale

Relation: info:eu-repo/semantics/altIdentifier/pmid/38510143; info:eu-repo/semantics/altIdentifier/wos/WOS:001221340100001; volume:27; issue:4; firstpage:1; lastpage:14; numberofpages:14; journal:ISCIENCE; https://hdl.handle.net/2434/1041348; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85188155050

الاتاحة: https://hdl.handle.net/2434/1041348
https://doi.org/10.1016/j.isci.2024.109359

المؤلفون: Faggiano, Andrea, Gherbesi, Elisa, Gnan, Eleonora, Paldino, Alessia, Merlo, Marco, Sinagra, Gianfranco, Carugo, Stefano

المصدر: European Journal of Heart Failure ; volume 26, issue 4, page 1097-1099 ; ISSN 1388-9842 1879-0844

الاتاحة: http://dx.doi.org/10.1002/ejhf.3248
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ejhf.3248

المؤلفون: Sozzi, Fabiola B., Gnan, Eleonora, Faggiano, Andrea, Giangiacomi, Francesco, Iacuzio, Laura, Canetta, Ciro, Santangelo, Gloria, Pisaniello, Marco, Eker, Armand, Carugo, Stefano

المصدر: Frontiers in Cardiovascular Medicine ; volume 11 ; ISSN 2297-055X

الاتاحة: http://dx.doi.org/10.3389/fcvm.2024.1367467
https://www.frontiersin.org/articles/10.3389/fcvm.2024.1367467/full

المؤلفون: Paolisso, Pasquale, Pavon, Anna Giulia, Bergamaschi, Luca, Angeli, Francesco, Belmonte, Marta, Foà, Alberto, Canton, Lisa, Fedele, Damiano, Armillotta, Matteo, Sansonetti, Angelo, Bodega, Francesca, Amicone, Sara, Suma, Nicole, Gallinoro, Emanuele, Attinà, Domenico, Niro, Fabio, Lovato, Luigi, Rucci, Paola, Gherbesi, Elisa, Carugo, Stefano, Mushtaq, Saima, Baggiano, Andrea, Guglielmo, Marco, Conte, Edoardo, Andreini, Daniele, Pontone, Gianluca, Pizzi, Carmine

المصدر: Journal of Cardiovascular Magnetic Resonance ; volume 26, page 100691 ; ISSN 1097-6647

الاتاحة: http://dx.doi.org/10.1016/j.jocmr.2024.100691
https://api.elsevier.com/content/article/PII:S1097664724006823?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1097664724006823?httpAccept=text/plain

المؤلفون: Pica, Silvia, Crimi, Gabriele, Castelvecchio, Serenella, Pazzanese, Vittorio, Palmisano, Anna, Lombardi, Massimo, Tondi, Lara, Esposito, Antonio, Ameri, Pietro, Canale, Claudia, Cappelletti, Alberto, Alberti, Luca P., Tavano, Davide, Camporotondo, Rita, Costantino, Ilaria, Campodonico, Jenness, Pontone, Gianluca, Villani, Alessandra, Gallone, Gianluca Pio, Montone, Rocco A., Niccoli, Giampaolo, Gargiulo, Paola, Punzo, Bruna, Vicenzi, Marco, Carugo, Stefano, Menicanti, Lorenzo, Ambrosio, Giuseppe, Camici, Paolo G.

المصدر: International Journal of Cardiology ; volume 402, page 131824 ; ISSN 0167-5273

الاتاحة: https://doi.org/10.1016/j.ijcard.2024.131824
https://api.elsevier.com/content/article/PII:S016752732400189X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S016752732400189X?httpAccept=text/plain

المؤلفون: Ammirati, Enrico, Lupi, Laura, Palazzini, Matteo, Ciabatti, Michele, Rossi, Valentina A, Gentile, Piero, Uribarri, Aitor, Vecchio, Chiara R, Nassiacos, Daniele, Cereda, Alberto, Conca, Cristina, Tumminello, Gabriele, Piriou, Nicolas, Lelarge, Coline, Pedrotti, Patrizia, Stucchi, Miriam, Peretto, Giovanni, Galasso, Michele, Huang, Florent, Ianni, Umberto, Procopio, Antonio, Saponara, Gianluigi, Cimaglia, Paolo, Tomasoni, Daniela, Moroni, Francesco, Turco, Annalisa, Sala, Simone, Di Tano, Giuseppe, Bollano, Entela, Moro, Claudio, Abbate, Antonio, Della Bona, Roberta, Porto, Italo, Carugo, Stefano, Campodonico, Jeness, Pontone, Gianluca, Grosu, Aurelia, Bolognese, Leonardo, Salamanca, Jorge, Diez-Villanueva, Pablo, Ozieranski, Krzysztof, Tyminska, Agata, Sardo Infirri, Loren, Bromage, Daniel, Cannatà, Antonio, Hong, Kimberly N, Adamo, Marianna, Quattrocchi, Giuseppina, Foà, Alberto, Potena, Luciano, Garascia, Andrea, Giannattasio, Cristina, Adler, Eric D, Sinagra, Gianfranco, Ruschitzka, Frank, Camici, Paolo G, Metra, Marco, Pieroni, Maurizio

المساهمون: Ammirati, Enrico, Lupi, Laura, Palazzini, Matteo, Ciabatti, Michele, Rossi, Valentina A, Gentile, Piero, Uribarri, Aitor, Vecchio, Chiara R, Nassiacos, Daniele, Cereda, Alberto, Conca, Cristina, Tumminello, Gabriele, Piriou, Nicola, Lelarge, Coline, Pedrotti, Patrizia, Stucchi, Miriam, Peretto, Giovanni, Galasso, Michele, Huang, Florent, Ianni, Umberto, Procopio, Antonio, Saponara, Gianluigi, Cimaglia, Paolo, Tomasoni, Daniela, Moroni, Francesco, Turco, Annalisa, Sala, Simone, Di Tano, Giuseppe, Bollano, Entela, Moro, Claudio, Abbate, Antonio, Della Bona, Roberta, Porto, Italo, Carugo, Stefano, Campodonico, Jene, Pontone, Gianluca, Grosu, Aurelia, Bolognese, Leonardo, Salamanca, Jorge, Diez-Villanueva, Pablo, Ozieranski, Krzysztof, Tyminska, Agata, Sardo Infirri, Loren, Bromage, Daniel, Cannatà, Antonio, Hong, Kimberly N, Adamo, Marianna, Quattrocchi, Giuseppina, Foà, Alberto, Potena, Luciano, Garascia, Andrea, Giannattasio, Cristina, Adler, Eric D, Sinagra, Gianfranco, Ruschitzka, Frank, Camici, Paolo G, Metra, Marco, Pieroni, Maurizio

مصطلحات موضوعية: COVID-19, COVID-19 vaccine, magnetic resonance spectroscopy, myocarditi, vaccination

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/37183708; volume:16; issue:6; firstpage:543; lastpage:548; numberofpages:6; journal:CIRCULATION. HEART FAILURE; https://hdl.handle.net/11368/3048260

الاتاحة: https://hdl.handle.net/11368/3048260
https://doi.org/10.1161/CIRCHEARTFAILURE.122.010315
https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.122.010315