المؤلفون: Manos Perros, Michael Mosley, Mark Stockdale, Patrick Dorr, Mike Westby, Caroline Smith-burchnell, Julie Mori, Susceptibility Assays, Indicates Viral

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jvi.asm.org/content/81/5/2359.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.497.3419; http://jvi.asm.org/content/81/5/2359.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.497.3419
http://jvi.asm.org/content/81/5/2359.full.pdf

المؤلفون: E. J. Murray, Frances Burden, Nigel Horscroft, Caroline Smith-burchnell, Mike Westby

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://aac.asm.org/content/55/9/4311.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1027.8365; http://aac.asm.org/content/55/9/4311.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1027.8365
http://aac.asm.org/content/55/9/4311.full.pdf

المؤلفون: Kathy F. K. Cheung, Jean-Yves Chiva, Satish Dayal, Darren Stead, Carly L. Nichols, Rob Webster, Lee R. Roberts, David Stonehouse, Felice Daverio, Iain Gardner, Andrew Pike, Michael Paradowski, David C. Blakemore, Gilles H. Goetz, Lesa Watson, Chris Pickford, Jared B.J. Milbank, Ye Che, Robert Wybrow, Florian Wakenhut, Keith Statham, Caroline Smith-Burchnell, Samuel Crook, Fiona M. Adam, David C. Pryde, David Leese, Mike Westby, Duncan Hay, Stephen M. Shaw, Tram T. Tran

المصدر: ChemMedChem. 9:1378-1386

مصطلحات موضوعية: Daclatasvir, Hepatitis C virus, Hepacivirus, Drug Evaluation, Preclinical, Drug resistance, Viral Nonstructural Proteins, Pharmacology, medicine.disease_cause, Antiviral Agents, Biochemistry, Virus, Cell Line, Structure-Activity Relationship, Dogs, Quinoxalines, Drug Resistance, Viral, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Potency, Protease Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, NS5A, biology, Organic Chemistry, Valine, biology.organism_classification, Virology, Rats, Microsomes, Liver, Molecular Medicine, Half-Life, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f34d031ac0ffb04451e59d88ca8e2e5
https://doi.org/10.1002/cmdc.201400045

المؤلفون: Stephen M. Shaw, David C. Pryde, Thien Duc Tran, Chris Pickford, Caroline Smith-Burchnell, M. J. Gardner, Rob Webster, Satish Dayal, Mike Westby, Tanya Parkinson

المصدر: Open Journal of Medicinal Chemistry. :16-25

مصطلحات موضوعية: viruses, Hepatitis C virus, Cell, Biology, medicine.disease_cause, Virology, Subgenomic replicon, medicine.anatomical_structure, Genotype 1b, Cell culture, medicine, Replicon, Cytotoxicity, Cell based

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::64f90ed16816176de539d01a7b3fb97c
https://doi.org/10.4236/ojmc.2013.31003

المؤلفون: Charles E. Mowbray, Lesley Fishburn, Christopher Phillips, Romuald Corbau, Steve Irving, Wendy Panton, Adele Thornberry, Caroline Smith-Burchnell, Manos Perros, Thorsten Knöchel, Heather J. Pfizer Global Res. Dev. Ringrose, Alex Martin, Mike Westby, Anthony Wood, Julie Mori

المصدر: Antimicrobial Agents and Chemotherapy. 54:4451-4463

مصطلحات موضوعية: Molecular Sequence Data, Mutant, Drug resistance, Crystallography, X-Ray, Antiviral Agents, Virus, Cell Line, Cell Line, Tumor, Drug Resistance, Viral, Nitriles, medicine, Humans, Pharmacology (medical), Pharmacology, chemistry.chemical_classification, biology, Reverse-transcriptase inhibitor, virus diseases, Biological activity, biology.organism_classification, Virology, HIV Reverse Transcriptase, Reverse transcriptase, Infectious Diseases, Enzyme, chemistry, Lentivirus, HIV-1, Mutagenesis, Site-Directed, Pyrazoles, Reverse Transcriptase Inhibitors, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6473fa865c73edbdbcd14f1835d6e2eb
https://doi.org/10.1128/aac.01455-09

المؤلفون: Patrick Dorr, Mike Westby, Manos Perros, Caroline Smith-Burchnell, Michael Mosley, Julie Mori, Marilyn Lewis, Mark Stockdale, Giuseppe Ciaramella

المصدر: Journal of Virology. 81:2359-2371

مصطلحات موضوعية: Receptors, CXCR4, Virus Cultivation, viruses, Aplaviroc, Molecular Sequence Data, Immunology, HIV Infections, CCR5 receptor antagonist, HIV Envelope Protein gp120, In Vitro Techniques, V3 loop, Biology, Virus Replication, Recombinant virus, Genes, env, Microbiology, Cell Line, Maraviroc, chemistry.chemical_compound, Cyclohexanes, HIV Fusion Inhibitors, Serial passage, Virology, Drug Resistance, Viral, Vaccines and Antiviral Agents, medicine, Humans, Amino Acid Sequence, Lymphocytes, CXCR4 antagonist, Genetic Variation, Triazoles, Peptide Fragments, Phenotype, Amino Acid Substitution, chemistry, Insect Science, CCR5 Receptor Antagonists, HIV-1, Mutagenesis, Site-Directed, Vicriviroc, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fe1213380659a2a05cef7581249899
https://doi.org/10.1128/jvi.02006-06

المؤلفون: Florian Wakenhut, Thien Duc Tran, Chris Pickford, Stephen Shaw, Mike Westby, Caroline Smith-Burchnell, Lesa Watson, Michael Paradowski, Jared Milbank, David Stonehouse, Kathy Cheung, Robert Wybrow, Felice Daverio, Samuel Crook, Keith Statham, David Leese, Darren Stead, Fiona Adam, Duncan Hay, Lee R. Roberts, Jean-Yves Chiva, Carly Nichols, David C. Blakemore, Gilles H. Goetz, Ye Che, Iain Gardner, Satish Dayal, Andrew Pike, Rob Webster, David C. Pryde

المصدر: ChemMedChem. 9(7)

مصطلحات موضوعية: Pharmacology, Cell Membrane Permeability, Organic Chemistry, Drug Evaluation, Preclinical, Hydrogen Bonding, Hepacivirus, Viral Nonstructural Proteins, Virus Replication, Biochemistry, Antiviral Agents, Cell Line, Rats, Structure-Activity Relationship, Dogs, Drug Discovery, Drug Resistance, Viral, Molecular Medicine, Animals, Humans, Protease Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6853494795d71988e823e2d45de7ec55
https://pubmed.ncbi.nlm.nih.gov/24729518

المؤلفون: Caroline Smith-Burchnell, Michael Westby, Nigel Horscroft, Edward J. Murray, Frances Burden

مصطلحات موضوعية: Hepatitis C virus, viruses, Blotting, Western, Alpha interferon, Biology, medicine.disease_cause, Antiviral Agents, Virus, Cell Line, Interferon, RNA interference, Endopeptidases, Ribavirin, medicine, Humans, Pharmacology (medical), Pharmacology, Gene knockdown, Reporter gene, Reverse Transcriptase Polymerase Chain Reaction, Interferon-alpha, Molecular biology, digestive system diseases, Infectious Diseases, RNA Interference, Signal transduction, Ubiquitin Thiolesterase, medicine.drug, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a398a5000336bb2caac9a071b60dc42f
https://europepmc.org/articles/PMC3165365/

المؤلفون: Julie Mori, Blanda Luzia Christa Stammen, Manos Perros, Armour Duncan Robert, Anthony Wood, Carolyn Napier, Becky Irvine, David Price, Susan Dobbs, Paul Griffin, Patrick Dorr, Caroline Smith-Burchnell, Mike Westby, Malcolm Macartney, Graham Rickett, Rob Webster

المصدر: Antimicrobial agents and chemotherapy. 49(11)

مصطلحات موضوعية: Male, Receptors, CCR5, Chemokine receptor CCR5, Anti-HIV Agents, Aplaviroc, viruses, Biological Availability, CCR5 receptor antagonist, Pharmacology, Membrane Fusion, Antiviral Agents, Maraviroc, Rats, Sprague-Dawley, chemistry.chemical_compound, Dogs, Viral envelope, In vivo, Viral entry, Cyclohexanes, Drug Resistance, Viral, medicine, Animals, Humans, Pharmacology (medical), Acquired Immunodeficiency Syndrome, biology, Triazoles, Virology, Rats, Infectious Diseases, chemistry, CCR5 Receptor Antagonists, biology.protein, HIV-1, Vicriviroc, Drug Therapy, Combination, medicine.drug, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ef7284f2bee7faeabb6349a3b346ff
https://pubmed.ncbi.nlm.nih.gov/16251317

المؤلفون: Lynne Bountiff, Caroline Smith-Burchnell, Graham Rickett, Jackie Gross, James R. Merson, Christina Baboonian, Peter F. Troke, Stephen Oroszlan, Angus G. Dalgleish

المصدر: Biochemical and biophysical research communications. 179(1)

مصطلحات موضوعية: Polyproteins, viruses, Molecular Sequence Data, Biophysics, Peptide, Immunodeficiency Virus, Feline, Virus Replication, Biochemistry, Virus, Cell Line, Substrate Specificity, chemistry.chemical_compound, HIV Protease, Proviruses, Humans, Amino Acid Sequence, Molecular Biology, chemistry.chemical_classification, biology, Base Sequence, virus diseases, Cell Biology, HIV Protease Inhibitors, Virology, Reverse transcriptase, Recombinant Proteins, Enzyme, chemistry, Viral replication, Enzyme inhibitor, DNA, Viral, biology.protein, HIV-1, Oligonucleotide Probes, Oligopeptides, Zidovudine, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3e8cfe89e86e0ea958c022779080d9
https://pubmed.ncbi.nlm.nih.gov/1652947