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المؤلفون: Hans G. Börner, Carmen Lawatscheck, Eckhard Mandelkow, Marcus Pickhardt, Sebastian Wieczorek, Andrea Grafmüller
المصدر: Angewandte Chemie, International Edition in English
Angewandte Chemie / International edition 55(30), 8752-8756 (2016). doi:10.1002/anie.201601147مصطلحات موضوعية: chemistry [Small Molecule Libraries], pharmacology [Small Molecule Libraries], Molecular Conformation, chemistry [Peptides], tau Proteins, Peptide, Molecular Dynamics Simulation, Protein aggregation, Spectrum Analysis, Raman, 010402 general chemistry, 01 natural sciences, Catalysis, Polyethylene Glycols, Small Molecule Libraries, Protein Aggregates, Alzheimer Disease, Peptide Library, drug therapy [Alzheimer Disease], Humans, Peptide library, chemistry.chemical_classification, Microscopy, 010405 organic chemistry, Chemistry, chemistry [tau Proteins], drug effects [Protein Aggregates], General Chemistry, Combinatorial chemistry, Fluorescence, Small molecule, metabolism [tau Proteins], Dynamic Light Scattering, 0104 chemical sciences, 3. Good health, chemistry [Polyethylene Glycols], Solubility, Solubilization, Drug Design, ddc:540, Peptides, therapeutic use [Small Molecule Libraries], Protein Binding, Conjugate
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2
المصدر: Current Alzheimer research 14(7), 742-752 (2017). doi:10.2174/1567205014666170202103136
Current Alzheimer Researchمصطلحات موضوعية: 0301 basic medicine, Rhodanine, Cell Survival, drug effects [Cell Survival], Tau protein, Biological Availability, Apoptosis, tau Proteins, Peptide, drug effects [Apoptosis], Transfection, Models, Biological, metabolism [Annexin A5], Mice, Protein Aggregates, 03 medical and health sciences, Peptide Library, Cell Line, Tumor, chemistry [Rhodanine], Animals, Humans, ddc:610, Viability assay, Annexin A5, chemistry.chemical_classification, Dose-Response Relationship, Drug, biology, Chemistry, drug effects [Protein Aggregates], N2a cell, metabolism [tau Proteins], In vitro, Bioavailability, genetics [tau Proteins], Cytosol, 030104 developmental biology, Microscopy, Fluorescence, Neurology, Biochemistry, pharmacology [Peptides], Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, biology.protein, Neurology (clinical), pharmacokinetics [Rhodanine], Trinucleotide Repeat Expansion, Peptides, genetics [Trinucleotide Repeat Expansion]
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3
المؤلفون: Anna Grafl, Marcus Pickhardt, Hans G. Börner, Eckhard Mandelkow, Katharina Linkert, Frank Polster, Carmen Lawatscheck
المصدر: Macromolecular Bioscience
Macromolecular bioscience 17(10), 1700109 (2017). doi:10.1002/mabi.201700109مصطلحات موضوعية: Polymers and Plastics, Peptide, 02 engineering and technology, Pharmaceutical formulation, 01 natural sciences, Polyethylene Glycols, chemistry [Nootropic Agents], chemistry.chemical_compound, chemical synthesis [Peptides], Materials Chemistry, drug therapy [Alzheimer Disease], metabolism [Nootropic Agents], Nootropic Agents, media_common, chemistry.chemical_classification, Drug Carriers, Aniline Compounds, 021001 nanoscience & nanotechnology, Small molecule, 3. Good health, Solutions, chemistry [Polyethylene Glycols], Biochemistry, Biological Assay, 0210 nano-technology, chemistry [Aniline Compounds], Biotechnology, chemistry [Sensory System Agents], Drug, Drug Compounding, media_common.quotation_subject, chemistry [Peptides], MAPT protein, human, tau Proteins, Bioengineering, 010402 general chemistry, Biomaterials, Protein Aggregates, Alzheimer Disease, ddc:570, PEG ratio, Humans, chemical synthesis [Drug Carriers], metabolism [Aniline Compounds], metabolism [Sensory System Agents], chemistry [tau Proteins], technology, industry, and agriculture, Combinatorial chemistry, 0104 chemical sciences, Drug Liberation, antagonists & inhibitors [tau Proteins], Solubility, chemistry, Solubilization, Sensory System Agents, Peptides, Ethylene glycol, Conjugate