المؤلفون: Sarah Rank Rønnow, Rand Qais Dabbagh, Federica Genovese, Carmel B. Nanthakumar, Vikki J. Barrett, Robert B. Good, Sarah Brockbank, Simon Cruwys, Henrik Jessen, Grith Lykke Sorensen, Morten Asser Karsdal, Diana Julie Leeming, Jannie Marie Bülow Sand

المصدر: Respiratory Research, Vol 21, Iss 1, Pp 1-14 (2020)

مصطلحات موضوعية: Scar-in-a-jar, Fibrogenesis, IPF, Fibroblasts, Collagens, Extracellular matrix, Diseases of the respiratory system, RC705-779

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12931-020-01369-1; https://doaj.org/toc/1465-993X

URL الوصول: https://doaj.org/article/7453a4c3b39244c08221644ac97d7ed3

المؤلفون: Louise A. Organ, Anne-Marie R. Duggan, Eunice Oballa, Sarah C. Taggart, Juliet K. Simpson, Arthur R. Kang’ombe, Rebecca Braybrooke, Philip L. Molyneaux, Bernard North, Yakshitha Karkera, Diana J. Leeming, Morten A. Karsdal, Carmel B. Nanthakumar, William A. Fahy, Richard P. Marshall, R. Gisli Jenkins, Toby M. Maher

المصدر: Respiratory Research, Vol 20, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: Diseases of the respiratory system, RC705-779

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12931-019-1118-7; https://doaj.org/toc/1465-993X

URL الوصول: https://doaj.org/article/bf04a004c4ea420686e599942cce6684

المؤلفون: Robert B. Good, Jessica D. Eley, Elaine Gower, Genevieve Butt, Andrew D. Blanchard, Andrew J. Fisher, Carmel B. Nanthakumar

المصدر: BMC Biomedical Engineering, Vol 1, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: Scar-in-a-jar, Extracellular matrix, ECM, Fibrosis, Fibroblast, Pulmonary fibrosis, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s42490-019-0014-z; https://doaj.org/toc/2524-4426

URL الوصول: https://doaj.org/article/aa6595ea4163483fa1924ec8e833f9df

المؤلفون: Hannah V. Woodcock, Jessica D. Eley, Delphine Guillotin, Manuela Platé, Carmel B. Nanthakumar, Matteo Martufi, Simon Peace, Gerard Joberty, Daniel Poeckel, Robert B. Good, Adam R. Taylor, Nico Zinn, Matthew Redding, Ellen J. Forty, Robert E. Hynds, Charles Swanton, Morten Karsdal, Toby M. Maher, Andrew Fisher, Giovanna Bergamini, Richard P. Marshall, Andy D. Blanchard, Paul F. Mercer, Rachel C. Chambers

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c3c84960b35344d79ec192d4954f0d3a

المؤلفون: Hannah V. Woodcock, Jessica D. Eley, Delphine Guillotin, Manuela Platé, Carmel B. Nanthakumar, Matteo Martufi, Simon Peace, Gerard Joberty, Daniel Poeckel, Robert B. Good, Adam R. Taylor, Nico Zinn, Matthew Redding, Ellen J. Forty, Robert E. Hynds, Charles Swanton, Morten Karsdal, Toby M. Maher, Andrew Fisher, Giovanna Bergamini, Richard P. Marshall, Andy D. Blanchard, Paul F. Mercer, Rachel C. Chambers

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/35a6295d2586420286eccc316b713105

المؤلفون: Shaun Fell, Carmel B. Nanthakumar, Zhuo Wang, Martin Griffin, Andy Blanchard

المصدر: Amino Acids

مصطلحات موضوعية: 0301 basic medicine, Tissue transglutaminase, Clinical Biochemistry, Transforming growth factor β1, Idiopathic pulmonary fibrosis, Biochemistry, Transforming Growth Factor beta1, 03 medical and health sciences, 0302 clinical medicine, GTP-Binding Proteins, Extracellular, medicine, Humans, Protein Glutamine gamma Glutamyltransferase 2, Smad3 Protein, Enzyme Inhibitors, Myofibroblasts, Lung, Transglutaminases, biology, Chemistry, Organic Chemistry, respiratory system, medicine.disease, Phenotype, Actins, Fibronectins, respiratory tract diseases, Fibronectin, Transglutaminase 2, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Original Article, Myofibroblast, Transforming growth factor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4619f66355f29e95e6d82de0fb273bb2
https://publications.aston.ac.uk/id/eprint/42269/1/Fell2021_Article_Transglutaminase2ANovelTherape.pdf

المؤلفون: Klio Maratou, Radu Rapiteanu, Eleni Patili, Matteo Martufi, Tobias Schmidt, Robert B. Good, Maria New, Carmel B. Nanthakumar, Andy Blanchard, Joanna Betts, Ketil Tvermosegaard

المصدر: The CRISPR Journal

مصطلحات موضوعية: Cell type, Genetic Vectors, Primary Cell Culture, Cell Culture Techniques, Smad Proteins, SMAD, Computational biology, Gene Knockout Techniques, Genome editing, Genetics, Humans, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Lung, Gene, Research Articles, Gene knockout, Ribonucleoprotein, Gene Editing, biology, Transforming growth factor beta, Fibroblasts, biology.protein, CRISPR-Cas Systems, Genetic Engineering, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e2a1ce9d2fe6fe8ab8cf1c4e1d9a68
https://doi.org/10.1089/crispr.2018.0047

المؤلفون: Luc Schoonjans, Git Chung, Rainie Cameron, Hannah L Paish, Rachel A. Burgoyne, Colin Nixon, Julie C. Worrell, Steven A. White, Matthias Trost, Derek Manas, Thomas G. Bird, Xin Xu, Stuart Robinson, Andrew J. Fisher, Ingmar Mederacke, Charlotte Bragg, Saimir Luli, Lucy M Gee, Ben S. Barksby, Colin D.A. Brown, Jack Leslie, Jeremy French, Neil S. Sheerin, Amy L Collins, Morten A. Karsdal, Andrew D Blanchard, Marco Y W Zaki, Gourab Sen, Robert F. Schwabe, Fiona Oakley, Peter Carmeliet, Amber Knox, Marina García Macia, Carmel B. Nanthakumar, Ulf Klein, Laure-Anne Teuwen, Johannes L Zakrzewski, Sandra Murphy, Lee A. Borthwick, Jelena Mann, Derek A. Mann, William J Reilly

المصدر: Nature Metabolism. 3:118-119

مصطلحات موضوعية: Energy dependent, Cell signaling, business.industry, Endocrinology, Diabetes and Metabolism, Liver fibrosis, Human kidney, Cell Biology, medicine.disease, Fibrosis, Physiology (medical), Internal Medicine, Cancer research, Medicine, Macrophage, business, REL, Reprogramming

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2454a7eff67728a24d84ed2616c20fad
https://doi.org/10.1038/s42255-020-00326-y

المؤلفون: Muzamil Majid, Khan, Daniel, Poeckel, Aliaksandr, Halavatyi, Joanna, Zukowska-Kasprzyk, Frank, Stein, Johanna, Vappiani, Daniel C, Sevin, Christian, Tischer, Nico, Zinn, Jessica D, Eley, Natasja Stæhr, Gudmann, Thomas, Muley, Hauke, Winter, Andrew J, Fisher, Carmel B, Nanthakumar, Giovanna, Bergamini, Rainer, Pepperkok

المصدر: The European respiratory journal. 58(1)

مصطلحات موضوعية: Proteomics, Transforming Growth Factor beta1, Microscopy, Pulmonary Fibrosis, Humans, Fibrosis, Lung

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::dee91691167c240ab81cb9789898fda6
https://pubmed.ncbi.nlm.nih.gov/34215663

المؤلفون: Johannes L Zakrzewski, Ben S. Barksby, Jeremy French, Luc Schoonjans, Amy L Collins, Jelena Mann, Matthias Trost, Stuart Robinson, Ulf Klein, Morten A. Karsdal, Hannah L Paish, Amber Knox, Peter Carmeliet, Lee A. Borthwick, Andrew D Blanchard, Git Chung, Rainie Cameron, Neil S. Sheerin, Laure-Anne Teuwen, Ingmar Mederacke, Lucy M Gee, Colin D.A. Brown, Carmel B. Nanthakumar, Thomas G. Bird, Jack Leslie, Sandra Murphy, Robert F. Schwabe, Fiona Oakley, Marina García Macia, Xin Xu, Andrew J. Fisher, Derek A. Mann, Derek Manas, Rachel A. Burgoyne, William J Reilly, Steven A. White, Charlotte Bragg, Saimir Luli, Gourab Sen, Marco Y W Zaki, Colin Nixon, Julie C. Worrell

المصدر: Nature Metabolism
Leslie, J, Macia, M G, Luli, S, Worrell, J C, Reilly, W J, Paish, H L, Knox, A, Barksby, B S, Gee, L M, Zaki, M Y W, Collins, A L, Burgoyne, R A, Cameron, R, Bragg, C, Xu, X, Chung, G W, Brown, C D A, Blanchard, A D, Nanthakumar, C B, Karsdal, M, Robinson, S M, Manas, D M, Sen, G, French, J, White, S A, Murphy, S, Trost, M, Zakrzewski, J L, Klein, U, Schwabe, R F, Mederacke, I, Nixon, C, Bird, T, Teuwen, L-A, Schoonjans, L, Carmeliet, P, Mann, J, Fisher, A J, Sheerin, N S, Borthwick, L A, Mann, D A & Oakley, F 2020, ' c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis ', Nature Metabolism, vol. 2, no. 11, pp. 1350-1367 . https://doi.org/10.1038/s42255-020-00306-2
Nat Metab
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Liver Cirrhosis, Cell signaling, Phosphofructokinase-2, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Liver fibrosis, Mitosis, Connective tissue, Epithelium, Article, Mice, Paracrine signalling, Fibrosis, Physiology (medical), Paracrine Communication, Internal Medicine, medicine, Animals, Macrophage, Monocytes and macrophages, Mice, Knockout, Chemistry, Macrophages, Growth factor, Mesenchymal stem cell, Cell Polarity, Cell Biology, medicine.disease, Proto-Oncogene Proteins c-rel, Liver Regeneration, Cell biology, Mice, Inbred C57BL, Hydroxyproline, medicine.anatomical_structure, Metabolism, Gene Targeting, Hepatocytes, REL, Cell signalling

وصف الملف: application/pdf; Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29e2b56012d84a4113925afd0985a4b

المؤلفون: Aliaksandr Halavatyi, Andrew J. Fisher, Rainer Pepperkok, Johanna Vappiani, Thomas Muley, Giovanna Bergamini, Christian Tischer, Natasja Staehr Gudmann, Jessica D. Eley, Daniel C. Sévin, Hauke Winter, Frank Stein, Muzamil Majid Khan, Nico Zinn, Carmel B. Nanthakumar, Daniel Poeckel

مصطلحات موضوعية: biology, Mesenchymal stem cell, Connective tissue, medicine.disease, GM6001, Cell biology, Fibronectin, Extracellular matrix, chemistry.chemical_compound, medicine.anatomical_structure, Metabolomics, chemistry, Fibrosis, medicine, biology.protein, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437819a77789c432109344be2540b042
https://doi.org/10.1101/2019.12.13.875963

المؤلفون: Elaine Gower, Andrew J. Fisher, Jessica D. Eley, Carmel B. Nanthakumar, Genevieve Butt, Robert B. Good, Andrew D Blanchard

المصدر: BMC Biomedical Engineering
BMC Biomedical Engineering, Vol 1, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: Cultural Studies, Linguistics and Language, History, lcsh:Medical technology, Phenotypic screening, lcsh:Biotechnology, Idiopathic pulmonary fibrosis, Language and Linguistics, Pulmonary fibrosis, Extracellular matrix, Collagen type I, Fibrosis, lcsh:TP248.13-248.65, medicine, Scar-in-a-jar, Fibroblast, ECM, biology, Chemistry, Drug discovery, Mesenchymal stem cell, Assay development, Fibrillogenesis, medicine.disease, Enzyme assay, Cell biology, medicine.anatomical_structure, IPF, lcsh:R855-855.5, Cell culture, Anthropology, High content imaging, biology.protein, Collagen, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061701406327c56552080780eddfa8da
http://europepmc.org/articles/PMC7422573

المؤلفون: Yim Man, Jessica D. Eley, Rachel C. Chambers, Natasja Stæhr Gudmann, William A. Fahy, Toby M. Maher, Andy Blanchard, Carmel B. Nanthakumar

المصدر: A29. EMERGING CONCEPTS IN LUNG FIBROSIS.

مصطلحات موضوعية: Extracellular matrix, Chemistry, Mechanism (biology), Phase (matter), Biomarker Analysis, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::126f3dc97d46ce25bb2955a46c9d7890
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7301

المؤلفون: Johanna Vappiani, Frank Stein, Carmel B. Nanthakumar, Andrew J. Fisher, Thomas Muley, Muzamil Majid Khan, Rainer Pepperkok, Aliaksandr Halavatyi, Hauke Winter, Giovanna Bergamini, Daniel C. Sévin, Daniel Poeckel, Christian Tischer, Nico Zinn, Jessica D. Eley, Natasja Stæhr Gudmann, Joanna Zukowska-Kasprzyk

المصدر: European Respiratory Journal. 58:2000221

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Cell type, business.industry, Mesenchymal stem cell, Connective tissue, medicine.disease, Cell biology, Extracellular matrix, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Metabolomics, Downregulation and upregulation, Fibrosis, 030220 oncology & carcinogenesis, Medicine, business, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::570d079b95ab2e764f485a39db1c7135
https://doi.org/10.1183/13993003.00221-2020

المؤلفون: Hannah V, Woodcock, Jessica D, Eley, Delphine, Guillotin, Manuela, Platé, Carmel B, Nanthakumar, Matteo, Martufi, Simon, Peace, Gerard, Joberty, Daniel, Poeckel, Robert B, Good, Adam R, Taylor, Nico, Zinn, Matthew, Redding, Ellen J, Forty, Robert E, Hynds, Charles, Swanton, Morten, Karsdal, Toby M, Maher, Andrew, Fisher, Giovanna, Bergamini, Richard P, Marshall, Andy D, Blanchard, Paul F, Mercer, Rachel C, Chambers

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications

مصطلحات موضوعية: Science, Cell Cycle Proteins, Mechanistic Target of Rapamycin Complex 1, Article, Cell Line, Transforming Growth Factor beta1, Phosphatidylinositol 3-Kinases, Signalling & Oncogenes, Ecology,Evolution & Ethology, MD Multidisciplinary, Humans, lcsh:Science, Adaptor Proteins, Signal Transducing, Computational & Systems Biology, Sirolimus, Chemical Biology & High Throughput, Human Biology & Physiology, TOR Serine-Threonine Kinases, Genome Integrity & Repair, Fibroblasts, respiratory system, Tumour Biology, Phosphoproteins, Idiopathic Pulmonary Fibrosis, respiratory tract diseases, lcsh:Q, Collagen, biological phenomena, cell phenomena, and immunity, Genetics & Genomics, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12557e14bc29bc74428c19dab93849b

المؤلفون: Diana Julie Leeming, Juliet Kay Simpson, Toby M. Maher, William A. Fahy, Carmel B. Nanthakumar, Rebecca Braybrooke, Philip L. Molyneaux, Gisli Jenkins, Eunice Oballa, Sarah C. Taggart, Louise Organ, Anne-Marie Duggan, Arthur R. Kang’ombe, Richard P. Marshall, Morten A. Karsdal

مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Disease progression, Therapeutic decision making, medicine.disease, Clinical trial, Extracellular matrix, Idiopathic pulmonary fibrosis, Stable Disease, Internal medicine, Cohort, medicine, business, Progressive disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60f05c745598b2a22073d2f84b107ce

المؤلفون: Eleni Patili, Andy Blanchard, Matteo Martufi, Joanna Betts, Robert B. Good, Ketil Tvermosegaard, Tobias Schmidt, Radu Rapiteanu, Carmel B. Nanthakumar, Klio Maratou

مصطلحات موضوعية: Cell type, Primary (chemistry), medicine.anatomical_structure, Genome editing, Cell, medicine, CRISPR, Computational biology, Biology, Gene, Type I collagen, Ribonucleoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c821a95d961d83ce06ed2dbaf790b94f
https://doi.org/10.1101/440099

المؤلفون: Jack Gauldie, Richard J. D. Hatley, Simon J. F. Macdonald, Seble Lemma, Carmel B. Nanthakumar, Richard P. Marshall

المصدر: Nature Reviews Drug Discovery. 14:693-720

مصطلحات موضوعية: Liver Cirrhosis, Drug, Pulmonary Fibrosis, media_common.quotation_subject, Pharmacology, Kidney, Bioinformatics, Idiopathic pulmonary fibrosis, Fibrosis, Drug Discovery, Pulmonary fibrosis, medicine, Renal fibrosis, Humans, Myofibroblasts, media_common, business.industry, Drug discovery, General Medicine, medicine.disease, Small molecule, Oxidative Stress, Drug development, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325f5c5282832a4eacc236abec1da6c8
https://doi.org/10.1038/nrd4592

المؤلفون: Jessica D. Eley, Paul F. Mercer, Hannah V. Woodcock, Carmel B. Nanthakumar, Rachel C. Chambers

المصدر: Mechanisms of Lung Injury and Repair.

مصطلحات موضوعية: Messenger RNA, business.industry, EIF4G, EIF4E, Repressor, Translation (biology), Cell biology, Eukaryotic initiation factor 4F, chemistry.chemical_compound, chemistry, Medicine, business, Myofibroblast, PI3K/AKT/mTOR pathway

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8fc5b4492b1b8dd69694d8e2faaaf698
https://doi.org/10.1183/1393003.congress-2017.pa3468

المؤلفون: Amanda L. Tatler, Rachel C. Chambers, Moises Selman, Mitchell Alan Olman, Eric S. White, Bethany B. Moore, Oliver Eickelberg, Melanie Königshoff, Andrew M. Tager, Dean Sheppard, Geoffrey J. Laurent, Patricia J. Sime, Annie Pardo, Carmel B. Nanthakumar, R. Gisli Jenkins, Victor J. Thannickal, Martin Kolb

المصدر: American journal of respiratory cell and molecular biology. 56(5)

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Male, medicine.medical_specialty, Pathology, Endpoint Determination, Pulmonary Fibrosis, Clinical Biochemistry, MEDLINE, Bleomycin, 03 medical and health sciences, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, Fibrosis, Pulmonary fibrosis, medicine, Animals, Humans, Intensive care medicine, Molecular Biology, Societies, Medical, American Thoracic Society Documents, Organisms, Genetically Modified, business.industry, Reproducibility of Results, Cell Biology, Therapeutic evaluation, Congresses as Topic, medicine.disease, Preclinical data, Clinical trial, Disease Models, Animal, 030104 developmental biology, chemistry, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a985d247b090da1ff0e3006bfbeb7451
https://pubmed.ncbi.nlm.nih.gov/28459387