المؤلفون: Ng, Bryan, Vowles, Jane, Bertherat, Féodora, Abey, Ajantha, Kilfeather, Peter, Beccano-Kelly, Dayne, Stefana, M. Irina, O'Brien, Darragh P., Bengoa-Vergniory, Nora, Carling, Phillippa J., Todd, John A., Caffrey, Tara M., Connor-Robson, Natalie, Cowley, Sally A., Wade-Martins, Richard

وصف الملف: application/pdf

Relation: https://orca.cardiff.ac.uk/id/eprint/169140/1/s41380-024-02463-2.pdf; Ng, Bryan, Vowles, Jane, Bertherat, Féodora, Abey, Ajantha, Kilfeather, Peter, Beccano-Kelly, Dayne https://orca.cardiff.ac.uk/view/cardiffauthors/A2639853M.html orcid:0000-0003-3592-8354 orcid:0000-0003-3592-8354, Stefana, M. Irina, O'Brien, Darragh P., Bengoa-Vergniory, Nora, Carling, Phillippa J., Todd, John A., Caffrey, Tara M., Connor-Robson, Natalie https://orca.cardiff.ac.uk/view/cardiffauthors/A095315G.html orcid:0000-0001-8350-6928 orcid:0000-0001-8350-6928, Cowley, Sally A. and Wade-Martins, Richard 2024. Tau depletion in human neurons mitigates Aβ-driven toxicity. Molecular Psychiatry 29 , pp. 2009-2020. 10.1038/s41380-024-02463-2 https://doi.org/10.1038/s41380-024-02463-2 file https://orca.cardiff.ac.uk/id/eprint/169140/1/s41380-024-02463-2.pdf

الاتاحة: https://orca.cardiff.ac.uk/id/eprint/169140/
https://doi.org/10.1038/s41380-024-02463-2

المؤلفون: Carling, Phillippa J, Ryan, Brent J, McGuinness, William, Kataria, Shikha, Humble, Stewart W, Milde, Stefan, Duce, James A, Kapadia, Nirav, Zuercher, William J, Davis, John B., Di Daniel, Elena, Wade-Martins, Richard

المساهمون: Parkinson’s UK, Medical Research Council (MRC) International Centre for Genomic Medicine in Neuromuscular Disease, Alzheimer’s Research UK

المصدر: Autophagy ; volume 19, issue 2, page 692-705 ; ISSN 1554-8627 1554-8635

الاتاحة: http://dx.doi.org/10.1080/15548627.2022.2095834
https://www.tandfonline.com/doi/pdf/10.1080/15548627.2022.2095834

المؤلفون: Lee, Heyne, Flynn, Rowan, Sharma, Ishta, Haberman, Emma, Carling, Phillippa J., Nicholls, Francesca J., Stegmann, Monika, Vowles, Jane, Haenseler, Walther, Wade-Martins, Richard, James, William S., Cowley, Sally A.

المساهمون: The Wellcome Trust, Oxford Martin School, MRC, ARUK, Innovative Medicines Initiative, European Union's Seventh Framework Program, EFPIA, Wellcome Trust Center for Human Genetics, National Phenotypic Screening Center, Oxford Parkinson's Disease Center, Parkinson's UK, National Institute for Health Research, Oxford Biomedical Research Center, NHS Trust, University of Oxford

المصدر: Stem Cell Reports ; volume 14, issue 5, page 940-955 ; ISSN 2213-6711

الاتاحة: http://dx.doi.org/10.1016/j.stemcr.2020.04.001
https://api.elsevier.com/content/article/PII:S2213671120301181?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2213671120301181?httpAccept=text/plain

المؤلفون: Otten, Auke B. C., Sallevelt, Suzanne C. E. H., Carling, Phillippa J., Dreesen, Joseph C. F. M., Drusedau, Marion, Spierts, Sabine, Paulussen, Aimee D. C., de Die-Smulders, Christine E. M., Herbert, Mary, Chinnery, Patrick F., Samuels, David C., Lindsey, Patrick, Smeets, Hubert J. M.

المصدر: Otten , A B C , Sallevelt , S C E H , Carling , P J , Dreesen , J C F M , Drusedau , M , Spierts , S , Paulussen , A D C , de Die-Smulders , C E M , Herbert , M , Chinnery , P F , Samuels , D C , Lindsey , P & Smeets , H J M 2018 , ' Mutation-specific effects in germline transmission of pathogenic mtDNA variants ' , Human Reproduction , vol. 33 , no. 7 , pp. 1331-1341 . https://doi.org/10.1093/humrep/dey114

مصطلحات موضوعية: mtDNA segregation, genetic drift, purifying selection, PGD, heteroplasmy, Kimura distribution, oxidative phosphorylation, mitochondrial membrane potential, MITOCHONDRIAL-DNA HETEROPLASMY, RANDOM GENETIC DRIFT, HUMAN EMBRYOFETAL DEVELOPMENT, LEIGH-SYNDROME, PRENATAL-DIAGNOSIS, NUCLEOTIDE 8993, IN-VITRO, RAPID SEGREGATION, HUMAN OOCYTES

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/f507f3d4-3bc7-4c48-9de1-7c8aef55639f
https://doi.org/10.1093/humrep/dey114

المؤلفون: Carling, Phillippa J, Ryan, Brent J, McGuinness, William, Kataria, Shikha, Humble, Stewart W, Milde, Stefan, Duce, James A, Kapadia, Nirav, Zuercher, William J, Davis, John B., Di Daniel, Elena, Wade-Martins, Richard

المصدر: Autophagy; Feb2023, Vol. 19 Issue 2, p692-705, 14p

مصطلحات موضوعية: LYSOSOMES, TRANSCRIPTION factors, PROTEIN kinases, HUNTINGTON disease, GENE regulatory networks, ALZHEIMER'S disease

المؤلفون: Rajan, Prabhakar, Dalgliesh, Caroline, Carling, Phillippa J., Buist, Thomas, Zhang, Chaolin, Grellscheid, Sushma N., Armstrong, Kelly, Stockley, Jacqueline, Simillion, Cedric, Gaughan, Luke, Kalna, Gabriela, Zhang, Michael Q., Robson, Craig N., Leung, Hing Y., Elliott, David J.

المساهمون: Chan, Franky L.

المصدر: PLoS ONE ; volume 6, issue 12, page e29088 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0029088
http://dx.plos.org/10.1371/journal.pone.0029088

المؤلفون: Carling, Phillippa J, Mortiboys, Heather, Green, Claire, Mihaylov, Simeon, Sandor, Cynthia, Schwartzentruber, Aurelie, Taylor, Rosie, Wei, Wenbin, Hastings, Chris, Wong, Siew, Lo, Christine, Evetts, Samuel, Clemmens, Hannah, Wyles, Matthew, Willcox, Sam, Payne, Thomas, Hughes, Rachel, Ferraiuolo, Laura, Webber, Caleb, Hide, Winston, Wade-Martins, Richard, Talbot, Kevin, Hu, Michele T., Bandmann, Oliver

وصف الملف: application/pdf

Relation: https://orca.cardiff.ac.uk/id/eprint/130327/1/Carling%20mechanistic.%20accepted%20with%20figures%207.2.20.pdf; Carling, Phillippa J, Mortiboys, Heather, Green, Claire, Mihaylov, Simeon, Sandor, Cynthia https://orca.cardiff.ac.uk/view/cardiffauthors/A23957926.html orcid:0000-0002-8905-1052 orcid:0000-0002-8905-1052, Schwartzentruber, Aurelie, Taylor, Rosie, Wei, Wenbin, Hastings, Chris, Wong, Siew, Lo, Christine, Evetts, Samuel, Clemmens, Hannah, Wyles, Matthew, Willcox, Sam, Payne, Thomas, Hughes, Rachel, Ferraiuolo, Laura, Webber, Caleb https://orca.cardiff.ac.uk/view/cardiffauthors/A2393081Q.html orcid:0000-0001-8063-7674 orcid:0000-0001-8063-7674, Hide, Winston, Wade-Martins, Richard, Talbot, Kevin, Hu, Michele T. and Bandmann, Oliver 2020. Deep phenotyping of peripheral tissue facilitates mechanistic disease stratification in sporadic Parkinson's disease. Progress in Neurobiology 187 , 101772. 10.1016/j.pneurobio.2020.101772 https://doi.org/10.1016/j.pneurobio.2020.101772 file https://orca.cardiff.ac.uk/id/eprint/130327/1/Carling%20mechanistic.%20accepted%20with%20figures%207.2.20.pdf

الاتاحة: https://orca.cardiff.ac.uk/id/eprint/130327/
https://doi.org/10.1016/j.pneurobio.2020.101772
https://orca.cardiff.ac.uk/id/eprint/130327/1/Carling%20mechanistic.%20accepted%20with%20figures%207.2.20.pdf

المؤلفون: Davis, Ryan L., Wong, Siew L., Carling, Phillippa J., Payne, Thomas, Sue, Carolyn M., Bandmann, Oliver

المصدر: Neurology Clinical Practice ; volume 10, issue 1, page 40-46 ; ISSN 2163-0402 2163-0933

الاتاحة: http://dx.doi.org/10.1212/cpj.0000000000000702
https://www.neurology.org/doi/pdfdirect/10.1212/CPJ.0000000000000702

المؤلفون: Otten, Auke BC, Sallevelt, Suzanne CEH, Carling, Phillippa J, Dreesen, Joseph CFM, Drüsedau, Marion, Spierts, Sabine, Paulussen, Aimee DC, de Die-Smulders, Christine EM, Herbert, Mary, Chinnery, Patrick F, Samuels, David C, Lindsey, Patrick, Smeets, Hubert JM

مصطلحات موضوعية: Adult, Blastomeres, DNA, Mitochondrial, Female, Germ Cells, Germ-Line Mutation, Humans, Male, Oocytes, Oxidative Phosphorylation

وصف الملف: Print; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Relation: https://www.repository.cam.ac.uk/handle/1810/283181

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/283181
https://doi.org/10.17863/CAM.30544

المؤلفون: Carling, Phillippa J., Cree, Lynsey M., Chinnery, Patrick F.

المصدر: Mitochondrion ; volume 11, issue 5, page 686-692 ; ISSN 1567-7249

الاتاحة: http://dx.doi.org/10.1016/j.mito.2011.05.004
https://api.elsevier.com/content/article/PII:S1567724911001929?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1567724911001929?httpAccept=text/plain