المؤلفون: Alexis Courbet, Nicole Bec, Caroline Constant, Christian Larroque, Martine Pugniere, Safia El Messaoudi, Zahraa Zghaib, Sonia Khier, Carine Deleuze-Masquefa, Florence Gattacceca

المصدر: PLoS ONE, Vol 12, Iss 8, p e0182022 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5552358?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/4641e264c43e45a79d28c8192d42093a

المؤلفون: Cindy Patinote, Sandy Raevens, Amélie Baumann, Eloise Pellegrin, Pierre-Antoine Bonnet, Carine Deleuze-Masquéfa

المصدر: Molecules, Vol 28, Iss 14, p 5478 (2023)

مصطلحات موضوعية: [1,2,4]triazolo[4,3-a]quinoxaline, pharmacophore, Imiqualines, EAPB02303, A375 melanoma cell line, cytotoxic activities, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/14/5478; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/3fe4f419bf2c46afb9661eec669a531f

المؤلفون: Adrien Chouchou, Cindy Patinote, Pierre Cuq, Pierre-Antoine Bonnet, Carine Deleuze-Masquéfa

المصدر: Molecules, Vol 23, Iss 11, p 2987 (2018)

مصطلحات موضوعية: imidazo[1,2-a]quinoxaline, melanoma, imiqualine, A375 structure–activity relationship, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/23/11/2987; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/1ffa6c3090ab47cd98c51f50d59e7d11

المؤلفون: Perla Makhoul, Simon Galas, Stéphanie Paniagua-Gayraud, Carine Deleuze-Masquefa, Hiba El Hajj, Pierre-Antoine Bonnet, Myriam Richaud

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 14, p 7785 (2024)

مصطلحات موضوعية: Caenorhabditis elegans, imiqualines, cancer, IIS pathway, DAF-16/FOXO, PI3K-Akt, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/14/7785; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/5197571b29ae4f91b95f4591a1f16bb1

الاتاحة: https://doi.org/10.3390/ijms25147785
https://doaj.org/article/5197571b29ae4f91b95f4591a1f16bb1

المؤلفون: Hala Skayneh, Batoul Jishi, Rita Hleihel, Maguy Hamie, Rana El Hajj, Carine Deleuze-Masquefa, Pierre-Antoine Bonnet, Marwan El Sabban, Hiba El Hajj

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3421

مصطلحات موضوعية: NPM1c AML, immunomodulatory drugs, post-translational modifications, ARF/NPM1/SENP3, P 53/HDM2

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Oncology; https://dx.doi.org/10.3390/ijms23073421

الاتاحة: https://doi.org/10.3390/ijms23073421

المؤلفون: Maguy Hamie, Rania Najm, Carine Deleuze-Masquefa, Pierre Antoine Bonnet, Jean-François Dubremetz, Marwan El Sabban, Hiba El Hajj

المصدر: Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: cerebral toxoplasmosis, acute toxoplasmosis, cytokines, reactivation, pathogen-host interaction, Immunologic diseases. Allergy, RC581-607

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.629917/full; https://doaj.org/toc/1664-3224; https://doaj.org/article/b01fac70466c4b6eb4135d538922689d

الاتاحة: https://doi.org/10.3389/fimmu.2021.629917
https://doaj.org/article/b01fac70466c4b6eb4135d538922689d

المؤلفون: Carine Deleuze-Masquéfa, Soulaima Chamat, Issam Kassab, Nour Bou Karroum, Pierre-Antoine Bonnet, Cindy Patinote, Mona Diab-Assaf, Hasnaa Bouharoun-Tayoun, Jean-François Guichou, Pierre Cuq, Georges Moarbess

المصدر: Journal of Medicinal Chemistry. 62:7015-7031

مصطلحات موضوعية: 0303 health sciences, Pyrazine, Antagonist, virus diseases, Stimulation, TLR7, TLR8, Pharmacology, 01 natural sciences, 0104 chemical sciences, 3. Good health, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Immune system, Quinoxaline, chemistry, Drug Discovery, Molecular Medicine, Receptor, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1f287a1be945fb10181dddf0365af346
https://doi.org/10.1021/acs.jmedchem.9b00411

المؤلفون: Carine Deleuze-Masquéfa, Kamel Hadj Kaddour, Pierre Cuq, Zahraa Zghaib, Cindy Patinote, Mona Diab Assaf, Laure-Anaïs Vincent, Pierre-Antoine Bonnet, Romain M. Larive, Jean-François Guichou

المصدر: European journal of medicinal chemistry. 212

مصطلحات موضوعية: Mitotic index, Cell Survival, Melanoma, Experimental, Mice, Nude, Antineoplastic Agents, 01 natural sciences, Malignant transformation, Polymerization, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Quinoxaline, Tubulin, Quinoxalines, Drug Discovery, medicine, Tumor Cells, Cultured, Animals, Humans, Vemurafenib, 030304 developmental biology, Cell Proliferation, Pharmacology, 0303 health sciences, Mice, Inbred BALB C, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Melanoma, Organic Chemistry, Biological activity, General Medicine, medicine.disease, Tubulin Modulators, 0104 chemical sciences, Molecular Docking Simulation, Mechanism of action, Cancer research, Skin cancer, medicine.symptom, Drug Screening Assays, Antitumor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fcf57d0cba9e1394c97c8471cc66d6
https://pubmed.ncbi.nlm.nih.gov/33309473

المؤلفون: Natalina Cirnat, Carine Deleuze-Masquéfa, Kamel Hadj-Kaddour, Cindy Patinote, Pierre-Antoine Bonnet, Pierre Cuq

المصدر: Journal of fluorescence. 30(6)

مصطلحات موضوعية: Sociology and Political Science, Clinical Biochemistry, 010402 general chemistry, 01 natural sciences, Biochemistry, law.invention, Confocal microscopy, law, Cell Line, Tumor, Quinoxalines, Humans, Spectroscopy, Fluorescent Dyes, Microscopy, Confocal, 010405 organic chemistry, Chemistry, Imidazoles, Colocalization, Biological Transport, Penetration (firestop), Fluorescence, 0104 chemical sciences, Clinical Psychology, Biophysics, Human melanoma, Protein target, Law, Social Sciences (miscellaneous)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616e8ac4d23a897cc739f3b5bc792b65
https://pubmed.ncbi.nlm.nih.gov/32778995

المؤلفون: Georges Moarbess, Natalina Cirnat, Nour Bou Karroum, Issam Kassab, Carine Deleuze-Masquéfa, Pierre-Antoine Bonnet, Cindy Patinote

المساهمون: Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Tumorigenèse et Pharmacologie Antitumorale, Lebanese University, EDST, BP 90656, Fanar Jdeideh, Lebanon

المصدر: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, ⟨10.1016/j.ejmech.2020.112238⟩

مصطلحات موضوعية: Agonist, medicine.drug_class, Endosome, Antineoplastic Agents, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Ligands, 01 natural sciences, Antiviral Agents, Article, 03 medical and health sciences, Oligonucleotide, Drug Discovery, medicine, Animals, Humans, [CHIM]Chemical Sciences, Receptor, TLRs 7/8, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, Pharmacology, 0303 health sciences, Biological Products, Molecular Structure, 010405 organic chemistry, Chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Heterocycle, Organic Chemistry, Toll-Like Receptors, General Medicine, 3. Good health, 0104 chemical sciences, Multiple pathologies, Anti-Bacterial Agents, Immunological modulators, Peptide, Signal transduction, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de7f9bd79045fce8ce9d640b42bd466
https://hal.archives-ouvertes.fr/hal-02826850

المؤلفون: Maguy Hamie (10275614), Rania Najm (10275617), Carine Deleuze-Masquefa (4348975), Pierre Antoine Bonnet (10275620), Jean-François Dubremetz (111711), Marwan El Sabban (10275623), Hiba El Hajj (10011178)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, cerebral toxoplasmosis, acute toxoplasmosis, cytokines, reactivation, pathogen-host interaction

Relation: https://figshare.com/articles/dataset/Table_1_Imiquimod_Targets_Toxoplasmosis_Through_Modulating_Host_Toll-Like_Receptor-MyD88_Signaling_DOCX/14185769

الاتاحة: https://doi.org/10.3389/fimmu.2021.629917.s001

المؤلفون: Cindy Patinote, Nour Bou Karroum, Carine Deleuze-Masquéfa, Mona Diab-Assaf, Pierre Cuq, Georges Moarbess, Pierre-Antoine Bonnet, Issam Kassab

المصدر: Chemistry of Heterocyclic Compounds. 54:183-187

مصطلحات موضوعية: Coupling, chemistry.chemical_compound, 010405 organic chemistry, Chemistry, Aryl, Organic Chemistry, Methylation, Bond formation, Alkylation, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3ead3b22ac22867697b29636349a8110
https://doi.org/10.1007/s10593-018-2252-8

المؤلفون: Céline Roques, Pierre Cuq, Françoise M.M. Bressolle-Gomeni, Pierre-Antoine Bonnet, Bénédicte Marion, Adrien Chouchou, Christine Enjalbal, Carine Deleuze-Masquéfa

المصدر: Journal of Pharmaceutical and Biomedical Analysis. 148:369-379

مصطلحات موضوعية: Male, 0301 basic medicine, Spectrometry, Mass, Electrospray Ionization, Bioanalysis, Electrospray ionization, Liquid-Liquid Extraction, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Mass spectrometry, High-performance liquid chromatography, Analytical Chemistry, Rats, Sprague-Dawley, Mice, Plasma, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Tandem Mass Spectrometry, Cell Line, Tumor, Quinoxalines, Drug Discovery, Animals, Humans, Chromatography, High Pressure Liquid, Spectroscopy, Active metabolite, Chromatography, Chemistry, Selected reaction monitoring, Rats, Mice, Inbred C57BL, Standard curve, 030104 developmental biology, 030220 oncology & carcinogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d610749a507171cc9f2e662fb87d1d8
https://doi.org/10.1016/j.jpba.2017.10.025

المؤلفون: Pierre-Antoine Bonnet, Marjorie Damian, Carine Deleuze-Masquéfa, Cindy Patinote, Kamel Hadj-Kaddour, Pierre Cuq

المصدر: Journal of Fluorescence. 27:1607-1611

مصطلحات موضوعية: Sociology and Political Science, 010405 organic chemistry, Clinical Biochemistry, 010402 general chemistry, Photochemistry, 01 natural sciences, Biochemistry, Fluorescence, 0104 chemical sciences, Clinical Psychology, chemistry.chemical_compound, Fluorescence intensity, Quinoxaline, chemistry, Emission spectrum, Absorption (chemistry), Law, Spectroscopy, Social Sciences (miscellaneous)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fde230a72543f6b1fc50b34d6a4c657
https://doi.org/10.1007/s10895-017-2097-z

المؤلفون: Carine Deleuze-Masquéfa, Cindy Patinote, Natalina Cirnat, Pierre-Antoine Bonnet

المصدر: Current medicinal chemistry. 28(4)

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Chemistry, Pharmaceutical, Organic Chemistry, Ring (chemistry), Biochemistry, Medicinal chemistry, chemistry.chemical_compound, Quinoxaline, chemistry, Heterocyclic Compounds, Quinoxalines, Drug Discovery, Rapid access, Molecular Medicine, Azole, Humans

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4702777d4908b6e928b74fac28180c5
https://pubmed.ncbi.nlm.nih.gov/32026768

المؤلفون: Jean-François Guichou, Pierre-Antoine Bonnet, Georges Moarbess, Olivier Marcadet, Adrien Chouchou, Fiona Leroy, Stéphanie Paniagua-Gayraud, Pierre Cuq, Rémi Ruédas, Carine Deleuze-Masquéfa

المصدر: European Journal of Medicinal Chemistry. 115:268-274

مصطلحات موضوعية: 0301 basic medicine, Drug Evaluation, Preclinical, IκB kinase, Molecular Docking Simulation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Quinoxaline, Quinoxalines, Drug Discovery, Binding site, Protein Kinase Inhibitors, Pharmacology, chemistry.chemical_classification, Organic Chemistry, I-Kappa-B Kinase, NF-κB, General Medicine, I-kappa B Kinase, 030104 developmental biology, chemistry, Biochemistry, Docking (molecular), 030220 oncology & carcinogenesis, Tricyclic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4493e0a4024dbd9bbfcab8c9a0585ef
https://doi.org/10.1016/j.ejmech.2016.03.006

المؤلفون: Adrien, Chouchou, Cindy, Patinote, Pierre, Cuq, Pierre-Antoine, Bonnet, Carine, Deleuze-Masquéfa

المصدر: Molecules

مصطلحات موضوعية: Imidazoles, Antineoplastic Agents, Article, Inhibitory Concentration 50, Structure-Activity Relationship, imidazo[1,2-a]quinoxaline, Solubility, Cell Line, Tumor, Quinoxalines, melanoma, Humans, A375 structure–activity relationship, Amino Acids, Cell Proliferation, imiqualine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::12234908d54b2b71517d5fda133eb5ad
https://pubmed.ncbi.nlm.nih.gov/30445763

المؤلفون: Martine Pugnière, Florence Gattacceca, Carine Deleuze-Masquéfa, Sonia Khier, Caroline Constant, Safia El Messaoudi, Zahraa Zghaib, Christian Larroque, Nicole Bec, Alexis Courbet

المساهمون: Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Université de Montpellier (UM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Salvy-Córdoba, Nathalie

المصدر: PLoS ONE
PLoS ONE, Public Library of Science, 2017, 12 (8), pp.e0182022. ⟨10.1371/journal.pone.0182022⟩
PLoS ONE, Vol 12, Iss 8, p e0182022 (2017)
PLoS ONE, 2017, 12 (8), pp.e0182022. ⟨10.1371/journal.pone.0182022⟩

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Cytotoxicity, lcsh:Medicine, Apoptosis, Plasma protein binding, Toxicology, Pathology and Laboratory Medicine, Biochemistry, Microtubules, Polymerization, chemistry.chemical_compound, Spectrum Analysis Techniques, 0302 clinical medicine, Tubulin, Medicine and Health Sciences, Colchicine, Cell Cycle and Cell Division, lcsh:Science, Cytoskeleton, Multidisciplinary, Cell Death, biology, Cell Cycle, Chemical Reactions, Drugs, Flow Cytometry, MESH: Antineoplastics Agents/pharmacology, Cell Death/drug effects, Colchicine/pharmacology, Computor simulation, Quinoxalynes/pharmacology, Tubulin/metabolism, Tubulin Modulators, 3. Good health, Cell biology, Molecular Docking Simulation, Chemistry, Cell Processes, Spectrophotometry, [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, 030220 oncology & carcinogenesis, Physical Sciences, Cytophotometry, Cellular Structures and Organelles, medicine.symptom, Research Article, Protein Binding, Antineoplastic Agents, [SDV.CAN]Life Sciences [q-bio]/Cancer, macromolecular substances, Research and Analysis Methods, 03 medical and health sciences, [SDV.CAN] Life Sciences [q-bio]/Cancer, Tubulins, Microtubule, Cell Line, Tumor, Quinoxalines, medicine, Humans, Computer Simulation, Binding site, Cell Proliferation, Pharmacology, Binding Sites, lcsh:R, Biology and Life Sciences, Proteins, Cell Biology, Polymer Chemistry, In vitro, Cytoskeletal Proteins, 030104 developmental biology, Mechanism of action, chemistry, Cancer cell, biology.protein, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, lcsh:Q

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccef2efe078371db4a506e110983e5d
https://hal.umontpellier.fr/hal-02316320

المؤلفون: Jean-Marie Devoisselle, Sylvie Bégu, Christophe Dorandeu, Carine Deleuze-Masquéfa, Adrien Chouchou, Pierre-Antoine Bonnet, Pierre Cuq, Anne Aubert-Pouëssel, Zahraa Zghaib

المساهمون: Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier (ICGM ICMMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC)

المصدر: International Journal of Pharmaceutical Investigation
International Journal of Pharmaceutical Investigation, Phcog.Net, 2017, 7 (4), ⟨10.4103/jphi.JPHI_53_17⟩

مصطلحات موضوعية: Dispersity, formulation, 02 engineering and technology, Pharmaceutical formulation, Nanocapsules, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, [CHIM]Chemical Sciences, Original Research Article, Solubility, imiqualines, Chromatography, Dimethyl sulfoxide, solubility, nanocapsules, General Medicine, 021001 nanoscience & nanotechnology, Bioavailability, chemistry, 030220 oncology & carcinogenesis, encapsulation, Cancer chemotherapy, 0210 nano-technology, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249638eae45247e1cb71da7a9d272651
https://hal.umontpellier.fr/hal-01930478/file/PharmInvestigations74155-1099154_030311.pdf

المؤلفون: Kamel Hadj-Kaddour, Issam Kassab, Cindy Patinote, Nour Bou Karroum, Pierre-Antoine Bonnet, Georges Moarbess, Pierre Cuq, Carine Deleuze-Masquéfa, Mona Diab-Assaf

المساهمون: Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Lebanese University [Beirut] (LU)

المصدر: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2017, 138, pp.909-919. ⟨10.1016/j.ejmech.2017.07.021⟩

مصطلحات موضوعية: 0301 basic medicine, Pyrazine, Stereochemistry, [SDV]Life Sciences [q-bio], [CHIM.THER]Chemical Sciences/Medicinal Chemistry, 01 natural sciences, NF-κB, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Quinoxaline, Quinoxalines, Drug Discovery, Pyrazoloquinoxaline, Structure–activity relationship, Imidazopyrazine, [CHIM]Chemical Sciences, Humans, Protein Kinase Inhibitors, Imidazoquinoxaline, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, IKK, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Organic Chemistry, Imidazoles, General Medicine, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, 0104 chemical sciences, 3. Good health, I-kappa B Kinase, 030104 developmental biology, Pyrazines, Pyrazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bc0f9ba5eb9f6ab228d32e37f6b83a
https://pubmed.ncbi.nlm.nih.gov/28750313