المؤلفون: Bárbara Velame Ferreira Teixeira, André Lacerda Braga Teles, Suellen Gonçalves da Silva, Camila Carane Bitencourt Brito, Humberto Fonseca de Freitas, Acássia Benjamim Leal Pires, Thamires Quadros Froes, Marcelo Santos Castilho

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1439-1450 (2019)

مصطلحات موضوعية: dual inhibitors, pteridine reductase 1, dihydrofolate reductase-thymidylate synthase, leishmania chagasi, selective inhibitors, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/47ffbc257e684a07b0e2938f725d0f05

المؤلفون: Antônio Rodolfo de Faria, Marcelo Santos Castilho, Daci José Brondani, Camila Carane Bitencourt Brito, Rafael Matos Ximenes, Ivanildo Mangueira da Silva, Hélder Vinicius Carneiro da Silva, Julianna Ferreira Cavalcanti de Albuquerque

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 333-342 (2019)

مصطلحات موضوعية: Biology, 01 natural sciences, Leishmania braziliensis, Superoxide dismutase, chemistry.chemical_compound, Structure-Activity Relationship, Cutaneous leishmaniasis, Drug Discovery, medicine, Humans, Enzyme Inhibitors, Thiazole, Leishmania, Pharmacology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Superoxide Dismutase, lcsh:RM1-950, Leishmaniasis, General Medicine, medicine.disease, biology.organism_classification, 0104 chemical sciences, thermal shift assay, 010404 medicinal & biomolecular chemistry, Thiazoles, lcsh:Therapeutics. Pharmacology, Enzyme, Drug development, chemistry, Biochemistry, biology.protein, thiazole derivatives, Brazil, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015f6ef55e0b3021310260d2b0cbaba0
https://pubmed.ncbi.nlm.nih.gov/30734600

المؤلفون: Camila Carane Bitencourt Brito, Marcelo Santos Castilho, Acássia Benjamim Leal Pires, Humberto Fonseca de Freitas, Bárbara Velame Ferreira Teixeira, André Lacerda Braga Teles, Thamires Quadros Froes, Suellen Gonçalves da Silva

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1439-1450 (2019)

مصطلحات موضوعية: leishmania chagasi, medicine.disease_cause, 01 natural sciences, Thymidylate synthase, pteridine reductase 1, Drug Discovery, Dihydrofolate reductase, parasitic diseases, medicine, Inhibitory concentration 50, Escherichia coli, Pharmacology, biology, 010405 organic chemistry, Chemistry, lcsh:RM1-950, selective inhibitors, General Medicine, Leishmania chagasi, biology.organism_classification, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, lcsh:Therapeutics. Pharmacology, Biochemistry, dihydrofolate reductase-thymidylate synthase, Toxicity, biology.protein, Leishmania infantum, Pteridine reductase 1, dual inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ae33c1875d51103f83ba86e1874c44

المؤلفون: Rafael Victorio Carvalho Guido, G.M.A. Lima, Fernando V. Maluf, Camila Carane Bitencourt Brito, Marcelo Santos Castilho

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: 0301 basic medicine, Leishmaniasis, Cutaneous, Bioengineering, Molecular cloning, Applied Microbiology and Biotechnology, Biochemistry, Leishmania braziliensis, Microbiology, Superoxide dismutase, 03 medical and health sciences, chemistry.chemical_compound, Cutaneous leishmaniasis, medicine, Humans, Cloning, Molecular, Molecular Biology, Cloning, chemistry.chemical_classification, biology, Superoxide Dismutase, Leishmaniasis, Hydrogen Peroxide, medicine.disease, biology.organism_classification, 030104 developmental biology, Enzyme, Pyrogallol, chemistry, DOENÇAS PARASITÁRIAS, biology.protein, Brazil, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97bc1427288b6446a71d411c9a1a45f4
https://pubmed.ncbi.nlm.nih.gov/29951736

المؤلفون: Odailson Santos Paz, Camila Carane Bitencourt Brito, Marcelo Santos Castilho

المصدر: Journal of enzyme inhibition and medicinal chemistry. 29(4)

مصطلحات موضوعية: Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, Adenosine A2B Receptor Antagonists, Quantitative Structure-Activity Relationship, General Medicine, Biology, Receptor, Adenosine A2B, Adenosine, Receptor subtype, Statistical quality, Drug development, Drug Design, Xanthines, Drug Discovery, medicine, Humans, Receptor, Adenosine A2B receptor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b794c2ec145a1b328fb8704a6cd2e6ea
https://pubmed.ncbi.nlm.nih.gov/24090420