المؤلفون: Shifali Shishodia (8610825), Marina Demetriades (716154), Dong Zhang (73558), Nok Yin Tam (11682099), Pratheesh Maheswaran (11682102), Caitlin Clunie-O’Connor (11682105), Anthony Tumber (765317), Ivanhoe K. H. Leung (10917799), Yi Min Ng (11682108), Thomas M. Leissing (11682111), Afaf H. El-Sagheer (1666675), Eidarus Salah (245308), Tom Brown (9263), Wei Shen Aik (4506667), Michael A. McDonough (716158), Christopher J. Schofield (233097)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, synthesized two series, selective fat mass, obesity associated protein, inducible factor prolyl, fe ­( ii, substrate binding sites, inhibitors fto catalyzes, 6 , substrate mimics, fto inhibitors, binding assays, vivo <, n <, using information, results illustrate, ray crystallography, proposed target, nucleic acids, kdms ), crystal structures

Relation: https://figshare.com/articles/journal_contribution/Structure-Based_Design_of_Selective_Fat_Mass_and_Obesity_Associated_Protein_FTO_Inhibitors/16991748

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01204.s001

المؤلفون: Afaf H. El-Sagheer, Ivanhoe K. H. Leung, Tom Brown, Michael A. McDonough, Anthony Tumber, Nok Yin Tam, Caitlin Clunie-O'Connor, Dong Zhang, Marina Demetriades, Shifali Shishodia, Wei Shen Aik, Thomas M. Leissing, Eidarus Salah, Pratheesh Maheswaran, Yi Min Ng, Christopher J. Schofield

المصدر: Journal of Medicinal Chemistry

مصطلحات موضوعية: Oxygenase, endocrine system diseases, AlkB, Alpha-Ketoglutarate-Dependent Dioxygenase FTO, Antineoplastic Agents, Crystallography, X-Ray, 010402 general chemistry, 01 natural sciences, Article, Mixed Function Oxygenases, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, Humans, Binding site, 030304 developmental biology, Demethylation, Histone Demethylases, chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, nutritional and metabolic diseases, Substrate (chemistry), pathological conditions, signs and symptoms, 0104 chemical sciences, Enzyme, Biochemistry, Drug Design, biology.protein, Nucleic acid, Molecular Medicine

وصف الملف: text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639c2be01f207a01903964a703615f30
https://ora.ox.ac.uk/objects/uuid:839b007e-dd4b-4bc0-ac22-ed37a4bd5169

المؤلفون: Paul R. Riley, Caitlin Clunie-O'Connor, Charalambos Antoniades, Anke M. Smits, Marie-José Goumans, Angela J. Russell, Derek M. Yellon

المصدر: Current Protocols in Stem Cell Biology

مصطلحات موضوعية: Cell type, Epithelial-Mesenchymal Transition, Cellular differentiation, Population, Cell Culture Techniques, Myocardial Infarction, Cell fate determination, Biology, Mice, Cell Movement, Transforming Growth Factor beta, Cell Adhesion, Animals, Humans, Myocyte, Myocytes, Cardiac, Heart Atria, education, Cell Proliferation, education.field_of_study, Heart development, Myocardium, Stem Cells, Regeneration (biology), Cell Differentiation, Cell Biology, General Medicine, Anatomy, Cell biology, Phenotype, cardiovascular system, Stem cell, Pericardium, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4793737aac332892f8be3e1b04887d
https://doi.org/10.1002/9780470151808.sc02c05s35