المؤلفون: Greenshields-Watson, Alexander, Vavourakis, Odysseas, Spoendlin, Fabian C., Cagiada, Matteo, Deane, Charlotte M.

المصدر: Current Opinion in Structural Biology ; volume 90, page 102983 ; ISSN 0959-440X

الاتاحة: https://doi.org/10.1016/j.sbi.2025.102983
https://api.elsevier.com/content/article/PII:S0959440X25000016?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0959440X25000016?httpAccept=text/plain

المؤلفون: Clausen, Lene, Voutsinos, Vasileios, Cagiada, Matteo, Johansson, Kristoffer E., Grønbæk-Thygesen, Martin, Nariya, Snehal, Powell, Rachel L., Have, Magnus K.N., Oestergaard, Vibe H., Stein, Amelie, Fowler, Douglas M., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus

المصدر: Clausen , L , Voutsinos , V , Cagiada , M , Johansson , K E , Grønbæk-Thygesen , M , Nariya , S , Powell , R L , Have , M K N , Oestergaard , V H , Stein , A , Fowler , D M , Lindorff-Larsen , K & Hartmann-Petersen , R 2024 , ' A mutational atlas for Parkin proteostasis ' , Nature Communications , vol. 15 , no. 1 , 1541 . https://doi.org/10.1038/s41467-024-45829-4

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/a-mutational-atlas-for-parkin-proteostasis(c4e2543f-94df-48bd-b6db-b93822049a9d).html
https://doi.org/10.1038/s41467-024-45829-4
https://curis.ku.dk/ws/files/384493234/s41467_024_45829_4.pdf

المؤلفون: Grønbæk-Thygesen, Martin, Voutsinos, Vasileios, Johansson, Kristoffer E., Schulze, Thea K., Cagiada, Matteo, Pedersen, Line, Clausen, Lene, Nariya, Snehal, Powell, Rachel L., Stein, Amelie, Fowler, Douglas M., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus

المصدر: Grønbæk-Thygesen , M , Voutsinos , V , Johansson , K E , Schulze , T K , Cagiada , M , Pedersen , L , Clausen , L , Nariya , S , Powell , R L , Stein , A , Fowler , D M , Lindorff-Larsen , K & Hartmann-Petersen , R 2024 , ' Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants ' , Nature Communications , vol. 15 , no. 1 , 4026 . https://doi.org/10.1038/s41467-024-48481-0

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/deep-mutational-scanning-reveals-a-correlation-between-degradation-and-toxicity-of-thousands-of-aspartoacylase-variants(9b3aded5-06f4-4528-9dab-23f579f1dbca).html
https://doi.org/10.1038/s41467-024-48481-0
https://curis.ku.dk/ws/files/392567888/s41467_024_48481_0.pdf

المؤلفون: Gersing, Sarah, Schulze, Thea K., Cagiada, Matteo, Stein, Amelie, Roth, Frederick P., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus

المصدر: Gersing , S , Schulze , T K , Cagiada , M , Stein , A , Roth , F P , Lindorff-Larsen , K & Hartmann-Petersen , R 2024 , ' Characterizing glucokinase variant mechanisms using a multiplexed abundance assay ' , Genome Biology , vol. 25 , no. 1 , 98 . https://doi.org/10.1186/s13059-024-03238-2

مصطلحات موضوعية: DMS, GCK, MAVE, Protein dynamics, Protein stability

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/characterizing-glucokinase-variant-mechanisms-using-a-multiplexed-abundance-assay(9bdd5ad9-6ddf-4ab9-9ac4-3594b36e5c7d).html
https://doi.org/10.1186/s13059-024-03238-2
https://curis.ku.dk/ws/files/389906153/s13059_024_03238_2.pdf

المؤلفون: Cagiada, Matteo, Ovchinnikov, Sergey, Lindorff-Larsen, Kresten

المصدر: Cagiada , M , Ovchinnikov , S & Lindorff-Larsen , K 2025 , ' Predicting absolute protein folding stability using generative models ' , Protein Science , vol. 34 , no. 1 , e5233 . https://doi.org/10.1002/pro.5233

مصطلحات موضوعية: machine learning, protein folding, protein stability, thermodynamics

الاتاحة: https://researchprofiles.ku.dk/da/publications/predicting-absolute-protein-folding-stability-using-generative-models(6182c2f1-f177-407f-ae98-8bdbecadb74f).html
https://doi.org/10.1002/pro.5233

المؤلفون: Kampmeyer, Caroline, Grønbæk-Thygesen, Martin, Oelerich, Nicole, Tatham, Michael H., Cagiada, Matteo, Lindorff-Larsen, Kresten, Boomsma, Wouter, Hofmann, Kay, Hartmann-Petersen, Rasmus

المصدر: Kampmeyer , C , Grønbæk-Thygesen , M , Oelerich , N , Tatham , M H , Cagiada , M , Lindorff-Larsen , K , Boomsma , W , Hofmann , K & Hartmann-Petersen , R 2023 , ' Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components ' , Cellular and molecular life sciences : CMLS , vol. 80 , no. 6 , 143 . https://doi.org/10.1007/s00018-023-04782-z

مصطلحات موضوعية: Humans, Proteasome Endopeptidase Complex, Ubiquitin, Lysine, Cytoplasm, Ubiquitination, Schizosaccharomyces/genetics, Molecular Chaperones, Autophagy-Related Proteins, Adaptor Proteins, Signal Transducing, Ubiquitin-Protein Ligases, PTM, Degradation, Intrinsically disordered protein, Proteasome, /dk/atira/pure/subjectarea/asjc/2800/2804, name=Cellular and Molecular Neuroscience, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/da7a012b-eb08-447a-a6bc-0de1a729c2b7
https://doi.org/10.1007/s00018-023-04782-z
https://discovery.dundee.ac.uk/ws/files/102577569/s00018_023_04782_z.pdf
http://www.scopus.com/inward/record.url?scp=85159027205&partnerID=8YFLogxK

المؤلفون: Blaabjerg, Lasse M, Kassem, Maher M, Good, Lydia L, Jonsson, Nicolas, Cagiada, Matteo, Johansson, Kristoffer E, Boomsma, Wouter, Stein, Amelie, Lindorff-Larsen, Kresten

مصطلحات موضوعية: biophysics, computational biology, genomic variants, machine learning, molecular biophysics, none, protein stability, structural biology, systems biology, Humans, Deep Learning, Proteins, Mutagenesis, Amino Acids

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/354206

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/354206

المؤلفون: Cagiada, Matteo, Bottaro, Sandro, Lindemose, Søren, Schenstrøm, Signe M., Stein, Amelie, Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten

المصدر: Cagiada , M , Bottaro , S , Lindemose , S , Schenstrøm , S M , Stein , A , Hartmann-Petersen , R & Lindorff-Larsen , K 2023 , ' Discovering functionally important sites in proteins ' , Nature Communications , vol. 14 , no. 1 , 4175 . https://doi.org/10.1038/s41467-023-39909-0

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/discovering-functionally-important-sites-in-proteins(ab7dcc3b-ced4-4b65-b0e5-685f95689654).html
https://doi.org/10.1038/s41467-023-39909-0
https://curis.ku.dk/ws/files/360248939/s41467_023_39909_0.pdf

المؤلفون: Blaabjerg, Lasse M., Kassem, Maher M., Good, Lydia L., Jonsson, Nicolas, Cagiada, Matteo, Johansson, Kristoffer E., Boomsma, Wouter, Stein, Amelie, Lindorff-Larsen, Kresten

المصدر: Blaabjerg , L M , Kassem , M M , Good , L L , Jonsson , N , Cagiada , M , Johansson , K E , Boomsma , W , Stein , A & Lindorff-Larsen , K 2023 , ' Rapid protein stability prediction using deep learning representations ' , eLife , vol. 12 , e82593 . https://doi.org/10.7554/eLife.82593

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/rapid-protein-stability-prediction-using-deep-learning-representations(8934c474-ac8e-4ea5-9509-a6fb0a76d3ba).html
https://doi.org/10.7554/eLife.82593
https://curis.ku.dk/ws/files/356971948/elife_82593_v2.pdf

المؤلفون: Gersing, Sarah, Cagiada, Matteo, Gebbia, Marinella, Gjesing, Anette P., Coté, Atina G., Seesankar, Gireesh, Li, Roujia, Tabet, Daniel, Weile, Jochen, Stein, Amelie, Gloyn, Anna L., Hansen, Torben, Roth, Frederick P., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus

المصدر: Gersing , S , Cagiada , M , Gebbia , M , Gjesing , A P , Coté , A G , Seesankar , G , Li , R , Tabet , D , Weile , J , Stein , A , Gloyn , A L , Hansen , T , Roth , F P , Lindorff-Larsen , K & Hartmann-Petersen , R 2023 , ' A comprehensive map of human glucokinase variant activity ' , Genome Biology , vol. 24 , no. 1 , 97 . https://doi.org/10.1186/s13059-023-02935-8

مصطلحات موضوعية: Deep mutational scanning, Diabetes, Variants of uncertain significance

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/a-comprehensive-map-of-human-glucokinase-variant-activity(49fe364a-ef79-45db-aa51-ddfd433ab041).html
https://doi.org/10.1186/s13059-023-02935-8
https://curis.ku.dk/ws/files/346047560/s13059_023_02935_8.pdf

المؤلفون: Gjesing, Anette P., Engelbrechtsen, Line, Cathrine B. Thuesen, Anne, Have, Christian T., Hollensted, Mette, Grarup, Niels, Linneberg, Allan, Steen Nielsen, Jens, Christensen, Lotte B., Thomsen, Reimar W., Johansson, Kristoffer E., Cagiada, Matteo, Gersing, Sarah, Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten, Vaag, Allan, Sørensen, Henrik T., Brandslund, Ivan, Beck-Nielsen, Henning, Pedersen, Oluf, Rungby, Jørgen, Hansen, Torben

المصدر: Gjesing , A P , Engelbrechtsen , L , Cathrine B. Thuesen , A , Have , C T , Hollensted , M , Grarup , N , Linneberg , A , Steen Nielsen , J , Christensen , L B , Thomsen , R W , Johansson , K E , Cagiada , M , Gersing , S , Hartmann-Petersen , R , Lindorff-Larsen , K , Vaag , A , Sørensen , H T , Brandslund , I , Beck-Nielsen , H , Pedersen , O , Rungby , J & Hansen , T 2022 , ' ....

مصطلحات موضوعية: Complications, Glucokinase, Macrovascular, Microvascular, MODY, Monogenic diabetes

وصف الملف: application/pdf

الاتاحة: https://pure.au.dk/portal/en/publications/48e449f1-fb13-42d7-8dfe-ef06fc7bfc8d
https://doi.org/10.1016/j.diabres.2022.110159
https://pure.au.dk/ws/files/336897168/14-fold_increased_prevalence_of_rare_glucokinase_gene_variant_carriers_in_unselected_Danish_patients_with_newly_diagnosed_type_2_diabetes.pdf
http://www.scopus.com/inward/record.url?scp=85143917075&partnerID=8YFLogxK

المؤلفون: Pacheco-Garcia, Juan Luis, Cagiada, Matteo, Tienne-Matos, Kelly, Salido, Eduardo, Lindorff-Larsen, Kresten, L. Pey, Angel

المصدر: Pacheco-Garcia , J L , Cagiada , M , Tienne-Matos , K , Salido , E , Lindorff-Larsen , K & L. Pey , A 2022 , ' Effect of naturally-occurring mutations on the stability and function of cancer-associated NQO1 : Comparison of experiments and computation ' , Frontiers in Molecular Biosciences , vol. 9 , 1063620 . https://doi.org/10.3389/fmolb.2022.1063620

مصطلحات موضوعية: protein function, protein stability, genotype-phenotype correlations, computational prediction, sequence conservation, MICE LEADS, BINDING, OXIDOREDUCTASE-1, SUSCEPTIBILITY, RECOGNITION, DEGRADATION, DISRUPTION, VARIANTS, NAD(P)H, GENE

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/effect-of-naturallyoccurring-mutations-on-the-stability-and-function-of-cancerassociated-nqo1(a2c2525d-e53c-4412-8589-01a351dc511e).html
https://doi.org/10.3389/fmolb.2022.1063620
https://curis.ku.dk/ws/files/329877407/fmolb_09_1063620.pdf

المؤلفون: Høie, Magnus Haraldson, Cagiada, Matteo, Frederiksen, Anders Haagen Beck, Stein, Amelie, Lindorff-Larsen, Kresten

المصدر: Høie , M H , Cagiada , M , Frederiksen , A H B , Stein , A & Lindorff-Larsen , K 2022 , ' Predicting and interpreting large-scale mutagenesis data using analyses of protein stability and conservation ' , Cell Reports , vol. 38 , no. 2 , 110207 . https://doi.org/10.1016/j.celrep.2021.110207

مصطلحات موضوعية: machine learning, protein evolution, protein stability, variant effects

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/predicting-and-interpreting-largescale-mutagenesis-data-using-analyses-of-protein-stability-and-conservation(9a2504b7-e1c4-47fb-91c2-d05e4666af6f).html
https://doi.org/10.1016/j.celrep.2021.110207
https://curis.ku.dk/ws/files/291540403/1_s2.0_S2211124721017113_main.pdf

المؤلفون: Cagiada, Matteo, Johansson, Kristoffer E., Valanciute, Audrone, Nielsen, Sofie V., Hartmann-Petersen, Rasmus, Yang, Jun J., Fowler, Douglas M., Stein, Amelie, Lindorff-Larsen, Kresten

المصدر: Cagiada , M , Johansson , K E , Valanciute , A , Nielsen , S V , Hartmann-Petersen , R , Yang , J J , Fowler , D M , Stein , A & Lindorff-Larsen , K 2021 , ' Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance ' , Molecular Biology and Evolution , vol. 38 , no. 8 , pp. 3235-3246 . https://doi.org/10.1093/molbev/msab095

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/understanding-the-origins-of-loss-of-protein-function-by-analyzing-the-effects-of-thousands-of-variants-on-activity-and-abundance(73185973-58b4-4080-9270-25474ae92ec7).html
https://doi.org/10.1093/molbev/msab095
https://curis.ku.dk/ws/files/279254324/Understanding_the_Origins_of_Loss_of_Protein_Function_by_Analyzing_the_Effects_of_Thousands_of_Variants_on_Activity_and_Abundance.pdf

المؤلفون: Cagiada, Matteo

المصدر: Cagiada , M 2023 , Understanding the Role of Individual Residues in Proteins : a Study of Missense Variants and their Impact on Function . Department of Biology, Faculty of Science, University of Copenhagen .

الاتاحة: https://curis.ku.dk/portal/da/publications/understanding-the-role-of-individual-residues-in-proteins(42abd610-dfe6-4851-9197-9b9ec5e23cae).html

المؤلفون: Larsen, Fia B., Cagiada, Matteo, Dideriksen, Jonas, Stein, Amelie, Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus

المصدر: Larsen , F B , Cagiada , M , Dideriksen , J , Stein , A , Lindorff-Larsen , K & Hartmann-Petersen , R 2023 , ' Rare Catechol- O -methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets ' , Biochemistry , vol. 62 , no. 8 .

مصطلحات الفهرس: article

URL: https://curis.ku.dk/portal/da/publications/rare-catecholomethyltransferase-missense-variants-are-structurally-unstable-proteasome-targets(9259b5dd-f6e3-4ef0-b924-77e66ad01453).html
https://doi.org/10.1021/acs.biochem.3c00008

المؤلفون: Franco, Giulia, Cagiada, Matteo, Bussi, Giovanni, Tiana, Guido

المساهمون: G. Franco, M. Cagiada, G. Bussi, G. Tiana

مصطلحات موضوعية: mean field, pseudo likelihood, Boltzmann learning, Settore FIS/03 - Fisica della Materia

Relation: info:eu-repo/semantics/altIdentifier/pmid/31018179; info:eu-repo/semantics/altIdentifier/wos/WOS:000470749900002; volume:16; issue:4; firstpage:1; lastpage:14; numberofpages:14; journal:PHYSICAL BIOLOGY; http://hdl.handle.net/2434/647912; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85067371724

الاتاحة: http://hdl.handle.net/2434/647912
https://doi.org/10.1088/1478-3975/ab1c15

المؤلفون: Gersing, Sarah, Cagiada, Matteo, Gebbia, Marinella, Gjesing, Anette P., Coté, Atina G., Seesankar, Gireesh, Li, Roujia, Tabet, Daniel, Weile, Jochen, Stein, Amelie, Gloyn, Anna L., Hansen, Torben, Roth, Frederick P., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f53121448056fb0e4ead78cb209f43

المؤلفون: Gersing, Sarah, Cagiada, Matteo, Gebbia, Marinella, Gjesing, Anette P., Coté, Atina G., Seesankar, Gireesh, Li, Roujia, Tabet, Daniel, Weile, Jochen, Stein, Amelie, Gloyn, Anna L., Hansen, Torben, Roth, Frederick P., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232d9389b4fdfd057fcefb5f4afaa3f9

المؤلفون: Gersing, Sarah, Cagiada, Matteo, Gebbia, Marinella, Gjesing, Anette P., Coté, Atina G., Seesankar, Gireesh, Li, Roujia, Tabet, Daniel, Weile, Jochen, Stein, Amelie, Gloyn, Anna L., Hansen, Torben, Roth, Frederick P., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25b4ca1eff46413aae31a0a9995f6b0