المؤلفون: Charleen G. Don, Martin Smieško

المصدر: Frontiers in Pharmacology, Vol 11 (2020)

مصطلحات موضوعية: CYP2D6 inhibition, natural products, molecular modeling, pharmacogenetics, adverse reactions, antidepressants, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2020.00683/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/1cf53596edde420584a4be1ad560fbc7

المؤلفون: Min JS, Kim D, Park JB, Heo H, Bae SH, Seo JH, Oh E, Bae SK

المصدر: Drug Design, Development and Therapy, Vol Volume 10, Pp 2959-2972 (2016)

مصطلحات موضوعية: Sarpogrelate hydrochloride, M-1, CYP2D6 inhibition, PBPK modeling, Drug-drug interaction, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.dovepress.com/application-of-physiologically-based-pharmacokinetic-modeling-in-predi-peer-reviewed-article-DDDT; https://doaj.org/toc/1177-8881

URL الوصول: https://doaj.org/article/3e976b9d7cbf4cbf9f0c61ab565cd431

المؤلفون: F. Schneider, P. S. Loupe, L. Rabinovich-Guilatt, M. F. Gordon, D. Stamler, M. J. Bradbury

المصدر: European Journal of Clinical Pharmacology

مصطلحات موضوعية: Adult, Male, Metabolic Clearance Rate, Tetrabenazine, Cmax, Deutetrabenazine, Pharmacology, Pharmacokinetics, Cytochrome P-450 CYP2D6 Inhibitors, Deuteration, Medicine, Humans, Pharmacology (medical), Drug Interactions, Adverse effect, Active metabolite, business.industry, General Medicine, Drug interaction, CYP2D6 inhibition, Paroxetine, Clinical Trial, Healthy Volunteers, Cytochrome P-450 CYP2D6, Area Under Curve, Vesicular Monoamine Transport Proteins, Female, business, medicine.drug, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd84a87777c1f82f5039ff8334c24a4c
https://pubmed.ncbi.nlm.nih.gov/34491372

المؤلفون: Charleen G. Don, Martin Smieško

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, CYP2D6 inhibition, natural products, molecular modeling, pharmacogenetics, adverse reactions, antidepressants, drug safety

Relation: https://figshare.com/articles/dataset/DataSheet_1_In_Silico_Pharmacogenetics_CYP2D6_Study_Focused_on_the_Pharmacovigilance_of_Herbal_Antidepressants_pdf/12292808

الاتاحة: https://doi.org/10.3389/fphar.2020.00683.s001
https://figshare.com/articles/dataset/DataSheet_1_In_Silico_Pharmacogenetics_CYP2D6_Study_Focused_on_the_Pharmacovigilance_of_Herbal_Antidepressants_pdf/12292808

المؤلفون: Koichi Ueno, Masanori Yamamoto, Noriko Harakawa, Shin Umeda

المصدر: Biological and Pharmaceutical Bulletin. 2005, 28(2):212

المؤلفون: Cazet, Lucie, Bulteau, Samuel, Evin, Adrien, Spiers, Andrew, Caillet, Pascal, Kuhn, Emmanuelle, Pivette, Jacques, Chaslerie, Anicet, Jolliet, Pascale, Victorri-Vigneau, Caroline

المساهمون: MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN)

المصدر: Expert opinion on drug metabolism & toxicology ; https://hal.science/hal-03158602 ; Expert opinion on drug metabolism & toxicology, 2018, 14 (8), pp.879-886. ⟨10.1080/17425255.2018.1496236⟩

مصطلحات موضوعية: Serotonin and Noradrenaline Reuptake Inhibitors, Review, Retrospective Studies, Pain, Middle Aged, Male, Humans, France, Female, Drug Interactions, Depression, Cytochrome P-450 CYP2D6 Inhibitors, CYP2D6 inhibition, Cohort Studies, Codeine, ArtThese, Antidepressive Agents, Antidepressant, Opioid, Analgesics, Adult, Adolescent, Serotonin Uptake Inhibitors, Young Adult, [SDV]Life Sciences [q-bio]

Relation: hal-03158602; https://hal.science/hal-03158602

الاتاحة: https://hal.science/hal-03158602
https://doi.org/10.1080/17425255.2018.1496236

المؤلفون: Anicet Chaslerie, Adrien Evin, Andrew Spiers, Jacques Pivette, Caroline Victorri-Vigneau, Pascal Caillet, Samuel Bulteau, Emmanuelle Kuhn, L. Cazet, Pascale Jolliet

المساهمون: MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques

المصدر: Expert opinion on drug metabolism & toxicology
Expert opinion on drug metabolism & toxicology, 2018, 14 (8), pp.879-886. ⟨10.1080/17425255.2018.1496236⟩

مصطلحات موضوعية: Adult, Male, CYP2D6, Adolescent, [SDV]Life Sciences [q-bio], Pain, Antidepressant, Opioid, Review, Pharmacology, Toxicology, 030226 pharmacology & pharmacy, Cytochrome P-450 CYP2D6 Inhibitors, Cohort Studies, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Medicine, Humans, Drug Interactions, 030212 general & internal medicine, Serotonin and Noradrenaline Reuptake Inhibitors, Serotonin Uptake Inhibitors, Depression (differential diagnoses), Retrospective Studies, Analgesics, business.industry, Codeine, Depression, General Medicine, Middle Aged, CYP2D6 inhibition, Antidepressive Agents, 3. Good health, ArtThese, Analgesics, Opioid, Female, Serotonin, France, business, Selective Serotonin Reuptake Inhibitors, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759530ffbfc7de4010f5e591cc46d5ad
https://hal.archives-ouvertes.fr/hal-03158602

المؤلفون: Gelston, E., Coller, J., Lopatko, O., James, H., Schmidt, H., White, J., Somogyi, A.

المصدر: http://dx.doi.org/10.1111/j.1365-2125.2011.04145.x.

مصطلحات موضوعية: Buprenorphine, codeine metabolism, CYP2D6 inhibition, glucuronidation inhibition, methadone

Relation: British Journal of Clinical Pharmacology, 2012; 73(5):786-794; http://hdl.handle.net/2440/72244; Coller, J. [0000-0002-8273-5048]; Somogyi, A. [0000-0003-4779-0380]

الاتاحة: http://hdl.handle.net/2440/72244
https://doi.org/10.1111/j.1365-2125.2011.04145.x

المؤلفون: Euichaul Oh, Jung Bae Park, Soo Kyung Bae, Hyunjin Heo, Jee Sun Min, Jae Hong Seo, Soo Hyeon Bae, Doyun Kim

المصدر: Drug Design, Development and Therapy

مصطلحات موضوعية: CYP2D6, Physiologically based pharmacokinetic modelling, Propanols, Pharmaceutical Science, Sarpogrelate, Pharmacology, Models, Biological, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, Desipramine, Drug Discovery, Humans, Medicine, Computer Simulation, Drug Interactions, Pharmacology (medical), Active metabolite, Original Research, PBPK modeling, Drug Design, Development and Therapy, sarpogrelate hydrochloride, business.industry, Area under the curve, Succinates, Dextromethorphan, M-1, CYP2D6 inhibition, Cytochrome P-450 CYP2D6, chemistry, 030220 oncology & carcinogenesis, business, Dimethylamines, medicine.drug

وصف الملف: text/html

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbcf9157201b7f66ee68a341c7e9329
https://doi.org/10.1016/j.clinthera.2016.07.167

المساهمون: Coller, Janet K, Michalakas, Jennifer R, James, Heather M, Farquharson, Aaron L, Colvill, Joel, White, Jason M, Somogyi, Andrew A

مصطلحات موضوعية: methadone, in vivo, tramadol metabolism, buprenorphine, CYP2D6 inhibition

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1231::32a46547fe4610a323985c204bc9cb95
https://hdl.handle.net/1959.8/134465

المساهمون: Gelston, Eloise, Coller, Janet K, Lopatko, Olga V, James, Heather M, Schmidt, Helmut, White, Jason M, Somogyi, Andrew A

مصطلحات موضوعية: methadone, codeine metabolism, buprenorphine, CYP2D6 inhibition, glucuronidation inhibition

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1231::64f7a075bcf16f00645500d5875b18af
https://hdl.handle.net/1959.8/132174

المؤلفون: Van, Linh M., Swales, John, Hammond, Clare, Wilson, Claire, Hargreaves, Judith A., Rostami-Hodjegan, Amin

المصدر: Van , L M , Swales , J , Hammond , C , Wilson , C , Hargreaves , J A & Rostami-Hodjegan , A 2007 , ' Kinetics of the time-dependent inactivation of CYP2D6 in cryopreserved human hepatocytes by methylenedioxymethamphetamine (MDMA) ' , European Journal of Pharmaceutical Sciences , vol. 31 , no. 1 , pp. 53-61 . https://doi.org/10.1016/j.ejps.2007.02.005

مصطلحات موضوعية: CYP2D6 inhibition, MDMA, Mechanism-based inhibition, Metabolic drug-drug interactions

الاتاحة: https://research.manchester.ac.uk/en/publications/0474422a-569d-4fb7-a3f0-4d59fb166fd3
https://doi.org/10.1016/j.ejps.2007.02.005

المؤلفون: 조, 두연

المساهمون: 대학원 의학과, 107795, 조, 두연

مصطلحات موضوعية: Sarpogrelate, CYP2D6 inhibition, Drug-Drug interaction, Metoprolol, Pharmacokinetics, Pharmacodynamics, CYP2D6 억제, 약물-약물 상호작용, 약동학, 약력학

Relation: http://repository.ajou.ac.kr/handle/201003/11856; http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000018795; 000000018795

الاتاحة: http://repository.ajou.ac.kr/handle/201003/11856
http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000018795