نتائج البحث - "CSF1R, colony-stimulating factor 1 receptor"

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 2, Pp 391-418 (2020)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Male, Colorectal cancer, Kaplan-Meier Estimate, Receptor tyrosine kinase, Metastasis, Epigenesis, Genetic, 0302 clinical medicine, GSEA, gene set enrichment analysis, miRNA, microRNA, TSA, trichostatin A, STAT3, Dox, doxycycline, qPCR, quantitative real-time polymerase chain reaction, Colectomy, Original Research, Feedback, Physiological, Proctectomy, Gastroenterology, EMT, Prognosis, mRNA, messenger RNA, 5-aza, 5-aza-2’-deoxycytidine, Gene Expression Regulation, Neoplastic, CMS, consensus molecular subtype, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, DNA methylation, CRC, colorectal cancer, 030211 gastroenterology & hepatology, TAM, tumor-associated macrophage, Female, Fluorouracil, RTK, receptor tyrosine kinase, EMT, epithelial-mesenchymal transition, Colorectal Neoplasms, Chemoresistance, STAT3 Transcription Factor, Epithelial-Mesenchymal Transition, Colon, Biology, 03 medical and health sciences, cDNA, complementary DNA, Cell Line, Tumor, microRNA, medicine, COAD, colon adenocarcinoma, Humans, 5-FU, lcsh:RC799-869, Transcription factor, CRIS, colorectal cancer intrinsic subtype, PDX, patient-derived xenograft, Hepatology, VIM, vimentin, Rectum, DNA Methylation, medicine.disease, IL, interleukin, MicroRNAs, 030104 developmental biology, Tumor progression, siRNA, small interfering RNA, Drug Resistance, Neoplasm, Cancer research, biology.protein, Tumor Progression, TCGA, The Cancer Genome Atlas, 5-FU, 5-fluorouracil, CpG Islands, lcsh:Diseases of the digestive system. Gastroenterology, EMT-TF, epithelial-mesenchymal transition–inducing transcription factor, Tumor Suppressor Protein p53, CSF1R, colony-stimulating factor 1 receptor, MSP, methylation-specific polymerase chain reaction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd6f32982ca09e25e86801417a279b4
http://www.sciencedirect.com/science/article/pii/S2352345X20300461

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6

Endotype–phenotyping may predict a treatment response in progressive fibrosing interstitial lung disease

المؤلفون: David J. Ross, Joseph P. Lynch, John A. Belperio, S. Samuel Weigt, Elizabeth R. Volkmann, Anna-Maria Hoffmann-Vold, Abbas Ardehali, Vyacheslav Palchevskiy, Rajan Saggar, Lloyd L. Liang

المصدر: EBioMedicine

مصطلحات موضوعية: Male, 0301 basic medicine, Endotype, Vital capacity, Research paper, VEGFR, Vascular Endothelial Growth Factor Receptor, medicine.medical_treatment, RA, rheumatoid arthritis, DLCO, diffusing capacity for carbon monoxide, 6MWD, six minute walking distance, Gastroenterology, Tfh, T follicular helper cells, Tyrosine-kinase inhibitor, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, 0302 clinical medicine, CTD, connective tissue disease, PF-ILD, progressive fibrosing-ILD, SD, Standard deviation, HRCT, high resolution computed tomography, ANOVA, analysis of variance, Outcome, Th2, T2 helper cells, M-CSF1R, M-colony stimulating factor, VEGF, Vascular Endothelial Growth Factor, Interstitial lung disease, General Medicine, Middle Aged, respiratory system, 3. Good health, Phenotype, 030220 oncology & carcinogenesis, Disease Progression, Cytokines, Female, Nintedanib, Disease Susceptibility, Inflammation Mediators, UCLA, University of California Los Angeles, PDGFRβ, Platelet derived growth factor receptor-beta, medicine.medical_specialty, FGFR, fibroblast growth factor receptor, medicine.drug_class, behavioral disciplines and activities, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, FEV1/FVC ratio, CSF1R, colony stimulating factor 1 receptor, Internal medicine, TGF-β, transforming growth factor beta, medicine, IPF, idiopathic pulmonary fibrosis, Humans, Lung transplantation, Lck, lymphocyte-specific tyrosine protein kinase, Connective tissue disease, Aged, SSc, systemic sclerosis, business.industry, Proteins, medicine.disease, FDA, Food and Drug Administration, FGF, fibroblast growth factor, respiratory tract diseases, body regions, HP, hypersensitivity pneumonitis, 030104 developmental biology, chemistry, PDGFRα, Platelet derived growth factor receptor-alpha, FVC, forced vital capacity, GAP, Global Alignment and Proportion, ILD, interstitial lung disease, PDGF, Platelet derived growth factor, Lung Diseases, Interstitial, business, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48fdbcec6e7f3d7376f99d487217c1e
https://doi.org/10.1016/j.ebiom.2019.10.050

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7

Academic Journal

The PRKAA1/AMPKalpha1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML.

المصدر: Autophagy, 11 (7), 1114-29 (2015)

مصطلحات موضوعية: AMP-Activated Protein Kinases/metabolism, Animals, Autophagy/drug effects, Calcium-Calmodulin-Dependent Protein Kinase Kinase/metabolism, Cell Differentiation/drug effects, Cell Line, Tumor, Enzyme Activation/drug effects, Humans, Leukemia, Myeloid/enzymology/pathology, Macrophage Colony-Stimulating Factor/pharmacology, Mice, Inbred C57BL, Models, Biological, Monocytes/cytology/drug effects/metabolism, Phospholipase C gamma/metabolism, Receptors, Purinergic P2/metabolism, Signal Transduction/drug effects, Uridine Diphosphate/pharmacology, ACTB actin, beta, CAMKK2, calcium/calmodulin-dependent protein kinase kinase 2, beta, CASP8, caspase 8, CFLAR CASP8 and FADD-like apoptosis regulator, CMML, CMML chronic myelomonocytic leukemia, CSF1, CSF1 colony stimulating factor 1 (macrophage), CSF1R colony stimulating factor 1 receptor, DEFA1 defensin alpha 1, DEFA3 defensin alpha 3 neutrophil-specific, DRS; dorsomorphin, EMR1 EGF-like module-containing mucin-like hormone receptor-like 1, FADD Fas (TNFRSF6)-associated via death domain, G-protein coupled 6, ITGAM integrin alpha M, MAP1LC3B/LC3B microtubule-associated protein 1 light chain 3 beta, P2RY6, P2RY6 pyrimidinergic receptor P2Y, PLC phospholipase, PLCB3 phospholipase C, PLCG2 phospholipase C gamma 2 (phosphatidylinositol-specific), PRKAA protein kinase AMP-activated, PRKAA1 protein kinase AMP-activated alpha 1 catalytic subunit, PRKAA1/AMPKalpha1, PRKAA2 protein kinase AMP-activated alpha 2 catalytic subunit, PRKAG1 protein kinase AMP-activated gamma 1 noncatalytic subunit, RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1, STK11 serine/threonine kinase 11, TFRC transferrin receptor, UDP uridine diphosphate, ULK1 unc-51 like autophagy activating kinase 1, WT wild-type, apoptosis-related cysteine peptidase, autophagy, differentiation, primary monocyte, beta 3 (phosphatidylinositol-specific), Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: urn:issn:1554-8627; urn:issn:1554-8635

URL الوصول: https://orbi.uliege.be/handle/2268/224277

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8

Myeloid Cell Mediated Immune Suppression in Pancreatic Cancer

المؤلفون: Marina Pasca di Magliano, Samantha Kemp, Howard C. Crawford

المصدر: Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: Myeloid, Cell, Cell Communication, Review, medicine.disease_cause, PD-1, programmed cell death, Tumor-Associated Macrophages, Tumor Microenvironment, Medicine, Cytotoxic T cell, CTLA-4, cytotoxic T lymphocyte antigen 4, Myeloid Cells, Neoplasm Metastasis, NF-κB, nuclear factor kappa B, TNF, tumor necrosis factor, Gastroenterology, IKK, inhibitory κB kinase, TME, tumor microenvironment, Disease Management, M-MDSC, mononuclear myeloid-derived suppressor cell, PDA, pancreatic ductal adenocarcinoma, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Cell Transformation, Neoplastic, TAM, tumor-associated macrophage, Disease Susceptibility, ADM, acinar to ductal metaplasia, Single-Cell Analysis, GM-CSF, granulocyte-macrophage colony-stimulating factor, Signal Transduction, education, PMN, polymorphonuclear, Immunomodulation, Immune system, MDSC, myeloid-derived suppressor cell, Pancreatic cancer, Animals, Humans, Cell Lineage, Tumor microenvironment, Hepatology, business.industry, Gene Expression Profiling, Myeloid-Derived Suppressor Cells, PanIN, pancreatic intraepithelial neoplasia, medicine.disease, Immune checkpoint, EGFR, epidermal growth factor receptor, IL, interleukin, Pancreatic Neoplasms, Drug Resistance, Neoplasm, Cancer research, HB-EGF, heparin-binding EGF-like growth factor, business, Carcinogenesis, CSF1R, colony-stimulating factor 1 receptor, Biomarkers, MAPK, mitogen-activated protein kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8338a0adf80bef867d358e27be771c97
https://pubmed.ncbi.nlm.nih.gov/34303882

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9

Wong-type dermatomyositis during anti–PD-1 therapy

المؤلفون: Wesley Y. Yu, Kanade Shinkai, Timothy H. McCalmont, Jeffrey P. North

المصدر: JAAD Case Reports

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6198cc911eddffd319dbe44faf26d5
http://europepmc.org/articles/PMC6232637

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10

The immune landscape of chondrosarcoma reveals an immunosuppressive environment in the dedifferentiated subtypes and exposes CSFR1+ macrophages as a promising therapeutic target

المؤلفون: Iseulys, Richert, Anne, Gomez-Brouchet, Corinne, Bouvier, Gonzague, Du Bouexic De Pinieux, Marie, Karanian, Jean-Yves, Blay, Aurélie, Dutour

المصدر: Journal of Bone Oncology

مصطلحات موضوعية: SMO, Smoothened Homolog Precursor, SIRPa, Signal regulatory protein alpha, Article, ICOS, Inducible Costimulator, CSF1R, Colony Stimulating Factor 1 Receptor, B7H3, B7 superfamily member-H3, hemic and lymphatic diseases, APC, Antigen Presenting Cells, CTLA4, cytotoxic T-lymphocyte–associated, MDR1, Multi Drug Resistance 1, TIM3, T cell immunoglobulin mucin, skin and connective tissue diseases, IDH, isocitrate deshydrogenase, CSF1, Colony Stimulating Factor 1, Treg, T regulator lymphocytes, integumentary system, PDL1, Programmed Death Ligand 1, LAG3, Lymphocyte activation gene-3, ICP, Immune checkpoint, CD, Cluster of Differentiation, HH, hedgehog, HLA, Human Leucocytes Antigen, CHS, Chondrosarcoma, TILs, Tumor Infiltrating Lymphocytes, TAMs, Tumor Associated Macrophages, ICOSL, inducible costimulator ligand, mTOR, mammalian Target Of Rapamycin, PD1, Programmed death 1, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::137809745bf56c1f8a4c5dca101c9a7b
https://pubmed.ncbi.nlm.nih.gov/32274326

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11

NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression

المؤلفون: Jungsoon Kang, Jennifer L. Larson-Casey, Linlin Gu, A. Brent Carter, Ashish Dhyani

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Male, 0301 basic medicine, Mitochondrial ROS, BAD, Bcl-2-associated death, Apoptosis, ASK1, apoptosis signal-regulating kinase 1, Biochemistry, Monocytes, Idiopathic pulmonary fibrosis, MMVF, man-made vitreous fiber, Fibrosis, Pulmonary fibrosis, AEC, alveolar epithelial cell, Phosphorylation, Lung, chemistry.chemical_classification, monocyte-derived macrophages, NOX4, Environmental exposure, BMDM, bone-marrow-derived macrophage, Mitochondria, NADPH Oxidase 4, Disease Progression, cardiovascular system, Female, bcl-Associated Death Protein, Research Article, PKB, protein kinase B, Models, Biological, Cell Line, apoptosis resistance, 03 medical and health sciences, ROS, reactive oxygen species, Csf1r, colony-stimulating factor 1 receptor, medicine, IPF, idiopathic pulmonary fibrosis, RAM, resident alveolar macrophage, Animals, NOX4, NADPH oxidase 4, Molecular Biology, Reactive oxygen species, pulmonary fibrosis, 030102 biochemistry & molecular biology, urogenital system, business.industry, Macrophages, Cell Biology, medicine.disease, Idiopathic Pulmonary Fibrosis, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Cancer research, MDM, monocyte-derived macrophage, Reactive Oxygen Species, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73149e7282c603c69a710a06ba330859
https://doi.org/10.1016/j.jbc.2021.100810

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