المؤلفون: Cuenca-Ardura, Mirabai

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: Ferrer, Jorge

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Beta cell, Transcription factor, Diabetes, CRISPR screen, Drug repurposing, Célula beta, Factor de transcripción, Reposicionamiento de fármacos

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/690221

المؤلفون: Barrero Asencio, Mercedes

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: Payer, Bernhard

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: X chromosome, Reprogramming, Pluripotency, CRISPR screen, Interferon γ, Cromosoma X, Reprogramación, Pluripotencia, Cribado de CRISPR, Interferón γ

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/687840

المؤلفون: Al-Azzam, Norah, To, Jenny H, Gautam, Vaishali, Street, Lena A, Nguyen, Chloe B, Naritomi, Jack T, Lam, Dylan C, Madrigal, Assael A, Lee, Benjamin, Jin, Wenhao, Avina, Anthony, Mizrahi, Orel, Mueller, Jasmine R, Ford, Willard, Schiavon, Cara R, Rebollo, Elena, Vu, Anthony Q, Blue, Steven M, Madakamutil, Yashwin L, Manor, Uri, Rothstein, Jeffrey D, Coyne, Alyssa N, Jovanovic, Marko, Yeo, Gene W

المصدر: Neuron. 112(24)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Neurodegenerative, ALS, Brain Disorders, Stem Cell Research - Induced Pluripotent Stem Cell, Genetics, Pediatric, Rare Diseases, Orphan Drug, Stem Cell Research, 2.1 Biological and endogenous factors, Neurological, Amyotrophic Lateral Sclerosis, Humans, RNA Splicing, Motor Neurons, Induced Pluripotent Stem Cells, DNA-Binding Proteins, RNA-Binding Proteins, Cell Nucleus, Phenotype, Active Transport, Cell Nucleus, CHMP7, CRISPR screen, RNA splicing, SMN complex, SmD1, TDP-43, amyotrophic lateral sclerosis, neurodegeneration, Psychology, Cognitive Sciences, Neurology & Neurosurgery, Biological psychology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7451d6dm
https://escholarship.org/content/qt7451d6dm/qt7451d6dm.pdf

المؤلفون: Oh, Sunwoo, Santiago, Gisselle, Manjunath, Lavanya, Li, Junyi, Bouin, Alexis, Semler, Bert L, Buisson, Rémi

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 121(45)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Emerging Infectious Diseases, Genetics, Infectious Diseases, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Infection, CRISPR-Cas Systems, Humans, Interferon Regulatory Factor-2, Endoribonucleases, 2', 5'-Oligoadenylate Synthetase, RNA Stability, Virus Diseases, Gene Knockout Techniques, RNA, Viral, HEK293 Cells, Virus Replication, STAT2 Transcription Factor, innate immunity, RNase, RNA decay, CRISPR screen, virus, RNase L

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3085n8nk
https://escholarship.org/content/qt3085n8nk/qt3085n8nk.pdf

المؤلفون: Rathore, Ujjwal, Haas, Paige, Kumar, Vigneshwari Easwar, Hiatt, Joseph, Haas, Kelsey M, Bouhaddou, Mehdi, Swaney, Danielle L, Stevenson, Erica, Zuliani-Alvarez, Lorena, McGregor, Michael J, Turner-Groth, Autumn, Olwal, Charles Ochieng', Bediako, Yaw, Braberg, Hannes, Soucheray, Margaret, Ott, Melanie, Eckhardt, Manon, Hultquist, Judd F, Marson, Alexander, Kaake, Robyn M, Krogan, Nevan J

المصدر: mBio. 15(4)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Immunology, Health Disparities, Sexually Transmitted Infections, Genetics, Minority Health, HIV/AIDS, Infectious Diseases, Clinical Research, 2.1 Biological and endogenous factors, 2.2 Factors relating to the physical environment, 1.1 Normal biological development and functioning, Generic health relevance, Infection, Humans, CCAAT-Enhancer-Binding Proteins, CD4-Positive T-Lymphocytes, CRISPR-Cas Systems, HIV Infections, TNF Receptor-Associated Factor 2, Ubiquitin-Protein Ligases, Ubiquitins, Virus Latency, Virus Replication, HIV, human immunodeficiency virus, ubiquitin E3 ligases, HIV latency, CRISPR screen, resting primary T cells, Microbiology, Biochemistry and cell biology, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/28x210fq
https://escholarship.org/content/qt28x210fq/qt28x210fq.pdf

المؤلفون: Xujie Cheng, Yuxing Wei, Limei Deng, Hao Dong, Huiping Wei, Cheng Xie, Yangjuan Tuo, Meiyu Chen, Hao Qin, Yong Cao

المصدر: Discover Oncology, Vol 15, Iss 1, Pp 1-12 (2024)

مصطلحات موضوعية: TOP2A, Oral squamous cell carcinoma, Biomarkers, Expression differences, CRISPR-screen, Single-cell RNA sequencing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2730-6011

URL الوصول: https://doaj.org/article/b3d280d0eb894a7eb1102f307b6316e1

المؤلفون: Tsuchida, Connor A, Brandes, Nadav, Bueno, Raymund, Trinidad, Marena, Mazumder, Thomas, Yu, Bingfei, Hwang, Byungjin, Chang, Christopher, Liu, Jamin, Sun, Yang, Hopkins, Caitlin R, Parker, Kevin R, Qi, Yanyan, Hofman, Laura, Satpathy, Ansuman T, Stadtmauer, Edward A, Cate, Jamie HD, Eyquem, Justin, Fraietta, Joseph A, June, Carl H, Chang, Howard Y, Ye, Chun Jimmie, Doudna, Jennifer A

المصدر: Cell. 186(21)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Immunology, Gene Therapy, Bioengineering, Biotechnology, Clinical Research, Genetics, 5.2 Cellular and gene therapies, 5.1 Pharmaceuticals, Cancer, Generic health relevance, Humans, Chromosomes, CRISPR-Cas Systems, DNA Damage, Gene Editing, T-Lymphocytes, Clinical Trials as Topic, Chromosome Aberrations, CAR T cells, CRISPR screen, CRISPR-Cas9, DNA repair, T cells, aneuploidy, chromosome loss, clinical trial, genome editing, immunoengineering, genome editing:, CAR T cells, Biological Sciences, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4111p9q6
https://escholarship.org/content/qt4111p9q6/qt4111p9q6.pdf

المؤلفون: Stéphanie Verbeke, Aurélien Bourdon, Mathilde Lafon, Vanessa Chaire, Bertolo Frederic, Amina Naït Eldjoudi, Marie-Alix Derieppe, Francis Giles, Antoine Italiano

المصدر: Translational Oncology, Vol 52, Iss , Pp 102236- (2025)

مصطلحات موضوعية: BET, Sarcoma, Ferroptosis, CRISPR screen, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523324003620; https://doaj.org/toc/1936-5233

URL الوصول: https://doaj.org/article/62d49593b9bd4936b2e9578a460027b6

المؤلفون: Ziqi Liu, Huan Gao, Guoliang Li, Yongjiang Yu, Mengxing Cui, Honghao Peng, Xinchao Guan, Xue Zhang, Zhihan Zhang, Xiaoyu Shen, Shen Chen, Daochuan Li, Liping Chen, Yongmei Xiao, Wen Chen, Lili Liu, Qing Wang

المصدر: Environment International, Vol 195, Iss , Pp 109234- (2025)

مصطلحات موضوعية: Genome-wide CRISPR screen, AAI, Nephrotoxicity, Apoptosis, CBD, Environmental sciences, GE1-350

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0160412024008213; https://doaj.org/toc/0160-4120

URL الوصول: https://doaj.org/article/90dbdc14de3f40818a08f06761391321

المؤلفون: Dingding Wang, Xinhao Zhang, Jianxun Guo, Weijia Liu, Yanchi Zhou, Renxian Wang

المصدر: Biochemistry and Biophysics Reports, Vol 40, Iss , Pp 101864- (2024)

مصطلحات موضوعية: TGF-β signaling, EXOSC10, Kinome-wide CRISPR screen, Biology (General), QH301-705.5, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405580824002280; https://doaj.org/toc/2405-5808

URL الوصول: https://doaj.org/article/aecbb43694934f1ab4f7ac48b6dfb829

المؤلفون: DiCiaccio, Benedetto, Seehawer, Marco, Li, Zheqi, Patmanidis, Andriana, Bui, Triet, Foidart, Pierre, Nishida, Jun, D'Santos, Clive S, Papachristou, Evangelia K, Papanastasiou, Malvina, Reiter, Andrew H, Qiu, Xintao, Li, Rong, Jiang, Yijia, Huang, Xiao-Yun, Simeonov, Anton, Kales, Stephen C, Rai, Ganesha, Lal-Nag, Madhu, Jadhav, Ajit, Brown, Myles, Carroll, Jason S, Long, Henry W, Polyak, Kornelia

المصدر: Cell Reports, 43 (12), 114991 (2024-12-24)

مصطلحات موضوعية: CP: Cancer, CRISPR screen, breast cancer, histone demethylase, mitochondrial signaling, Transcription Factors, DNA-Binding Proteins, KDM5A protein, human, ZBTB7A protein, human, Retinoblastoma-Binding Protein 2, Histones, NF-kappa B, Humans, Female, Cell Line, Tumor, Gene Regulatory Networks, Retinoblastoma-Binding Protein 2/metabolism, Retinoblastoma-Binding Protein 2/genetics, Histones/metabolism, Promoter Regions, Genetic/genetics, NF-kappa B/metabolism, Animals, Breast Neoplasms/genetics, Breast Neoplasms/pathology, Breast Neoplasms/metabolism, Transcription Factors/metabolism, Transcription Factors/genetics, DNA-Binding Proteins/metabolism, DNA-Binding Proteins/genetics, Gene Expression Regulation, Neoplastic, Breast Neoplasms, Promoter Regions, Genetic, Biochemistry, Genetics and Molecular Biology (all), Human health sciences, Oncology, Sciences de la santé humaine, Oncologie

Relation: https://api.elsevier.com/content/article/PII:S2211124724013421?httpAccept=text/xml; urn:issn:2211-1247

URL الوصول: https://orbi.uliege.be/handle/2268/327518

المؤلفون: Krishnamurthy, Shruthi, Maru, Parag, Wang, Yifan, Bitew, Mebratu A, Mukhopadhyay, Debanjan, Yamaryo-Botté, Yoshiki, Paredes-Santos, Tatiana C, Sangaré, Lamba O, Swale, Christopher, Botté, Cyrille Y, Saeij, Jeroen PJ

المصدر: mBio. 14(2)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Genetics, Infectious Diseases, Emerging Infectious Diseases, Human Genome, Biodefense, Prevention, 2.1 Biological and endogenous factors, Infection, Humans, Animals, Mice, Toxoplasma, Parasites, Interferon-gamma, Clustered Regularly Interspaced Short Palindromic Repeats, Virulence, Protozoan Proteins, CRISPR screen, Toxoplasma gondii, effector functions, host-pathogen interactions, interferons, Microbiology, Biochemistry and cell biology, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8k5121gp
https://escholarship.org/content/qt8k5121gp/qt8k5121gp.pdf

المؤلفون: Brittany Henry, Aubrey J. Phillips, L. David Sibley, Alex Rosenberg

المصدر: mBio, Vol 15, Iss 10 (2024)

مصطلحات موضوعية: intracellular parasite, host-pathogen interactions, CRISPR screen, secretory proteins, dense granule proteins, interferon gamma, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/03e35d06cafa44b5841a8ea8a7076d19

المؤلفون: Yuta Tachibana, Miwa Sasai, Masahiro Yamamoto

المصدر: mBio, Vol 15, Iss 9 (2024)

مصطلحات موضوعية: Toxoplasma, CRISPR screen, hyperLOPIT-unassigned virulence factors, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/227e0286daf84a9b821d06b7e3cc15db

المؤلفون: Montoya, Vanessa R, Ready, Trine M, Felton, Abby, Fine, Sydney R, OhAinle, Molly, Emerman, Michael

المصدر: mBio. 14(1)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Immunology, HIV/AIDS, Human Genome, Infectious Diseases, Sexually Transmitted Infections, Genetics, 2.2 Factors relating to the physical environment, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Infection, Good Health and Well Being, Humans, HIV-1, Virus Replication, Clustered Regularly Interspaced Short Palindromic Repeats, Cell Line, HIV Infections, Host-Pathogen Interactions, Transcription Factors, Co-Repressor Proteins, Cation Transport Proteins, Ubiquitin-Conjugating Enzymes, CRISPR screen, T cells, dependency factor, human immunodeficiency virus, transcription factors, virus replication, Microbiology, Biochemistry and cell biology, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9v8152b9
https://escholarship.org/content/qt9v8152b9/qt9v8152b9.pdf

المؤلفون: Nyberg, William A, Ark, Jonathan, To, Angela, Clouden, Sylvanie, Reeder, Gabriella, Muldoon, Joseph J, Chung, Jing-Yi, Xie, William H, Allain, Vincent, Steinhart, Zachary, Chang, Christopher, Talbot, Alexis, Kim, Sandy, Rosales, Alan, Havlik, L Patrick, Pimentel, Harold, Asokan, Aravind, Eyquem, Justin

المصدر: Cell. 186(2)

مصطلحات موضوعية: Medical Biotechnology, Biomedical and Clinical Sciences, Biotechnology, Genetics, Gene Therapy, 5.2 Cellular and gene therapies, 5.1 Pharmaceuticals, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Animals, Mice, CRISPR-Cas Systems, Dependovirus, Gene Targeting, Genetic Engineering, T-Lymphocytes, AAV, CAR-T cell, CRISPR/Cas9, Gene Editing, Gene targeting, Genome wide CRISPR screen, Immunology, T cell, Trac-CAR, Biological Sciences, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7th4849j
https://escholarship.org/content/qt7th4849j/qt7th4849j.pdf

المؤلفون: Simirenko, Lisa, Cheng, Jan-Fang, Blaby, Ian

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Genetics, Bioengineering, Biotechnology, Human Genome, Generic health relevance, CRISPR, CRISPR screen, batch DNA extraction, design tool, gRNA, Other Biological Sciences, Biomedical Engineering, Medical Biotechnology, Industrial biotechnology, Medical biotechnology, Biomedical engineering

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5h6003rn
https://escholarship.org/content/qt5h6003rn/qt5h6003rn.pdf

المؤلفون: Benaglio, Paola, Zhu, Han, Okino, Mei-Lin, Yan, Jian, Elgamal, Ruth, Nariai, Naoki, Beebe, Elisha, Korgaonkar, Katha, Qiu, Yunjiang, Donovan, Margaret KR, Chiou, Joshua, Wang, Gaowei, Newsome, Jacklyn, Kaur, Jaspreet, Miller, Michael, Preissl, Sebastian, Corban, Sierra, Aylward, Anthony, Taipale, Jussi, Ren, Bing, Frazer, Kelly A, Sander, Maike, Gaulton, Kyle J

المصدر: Cell Genomics. 2(12)

مصطلحات موضوعية: Biochemistry and Cell Biology, Genetics, Biological Sciences, Diabetes, Human Genome, Biotechnology, Pediatric, Autoimmune Disease, Prevention, 2.1 Biological and endogenous factors, Inflammatory and immune system, Metabolic and endocrine, 3D chromatin interactions, CRISPR screen, accessible chromatin, beta cell, functional genomics, gene expression, high-throughput reporter assay, human genetics, proinflammatory cytokines, type 1 diabetes

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8wv9b80n
https://escholarship.org/content/qt8wv9b80n/qt8wv9b80n.pdf

المؤلفون: Minghua Xiang, Huayi Li, Yuanyuan Zhan, Ding Ma, Qinglei Gao, Yong Fang

المصدر: Molecular Cancer, Vol 23, Iss 1, Pp 1-28 (2024)

مصطلحات موضوعية: CRISPR screen, T cell, Tumour immunity, Cancer immunotherapy, Adoptive cell therapy, Immune checkpoint inhibitor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1476-4598

URL الوصول: https://doaj.org/article/7d846df1b4ac4f3991ca2e27bf54b911

المؤلفون: Wanqing Tan, Zhiyuan Wang, Liezhao Liu

المصدر: Agriculture, Vol 15, Iss 1, p 29 (2024)

مصطلحات موضوعية: CRISPR–Cas, precise editing, CRISPR screen, transgene-free, crop improvement, Agriculture (General), S1-972

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2077-0472/15/1/29; https://doaj.org/toc/2077-0472

URL الوصول: https://doaj.org/article/90814bed0af5461098366a726bd26e93