المؤلفون: Jun Li, Cuiyun Zhang, Yuping Guan, Siyu Wang, Jiawen Zheng, Junnan Feng, Sile Han, Ruijuan Ma, Pengfei Ren, Shasha Li, Harry J. M. Groen, Klaas Kok, Anke van den Berg, Bing Wei, Jie Ma, Hongle Li, Yongjun Guo

المصدر: Holistic Integrative Oncology, Vol 3, Iss 1, Pp 1-10 (2024)

مصطلحات موضوعية: Lung adenocarcinoma, EGFR, TKI sensitivity, Rare mutations, Compound mutations, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2731-4529

URL الوصول: https://doaj.org/article/3dc4e66898d84391b36cf24c6a64f6d8

المؤلفون: Liu Z, Song P, Zhou L, Ji D, Shen H, Dong H, Feng X

المصدر: Cancer Management and Research, Vol Volume 15, Pp 645-650 (2023)

مصطلحات موضوعية: lung adenocarcinoma, compound mutations, osimertinib, crizotinib, combination therapy, case report, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.dovepress.com/osimertinib-for-an-advanced-nsclc-patient-with-two-common-egfr-mutatio-peer-reviewed-fulltext-article-CMAR; https://doaj.org/toc/1179-1322

URL الوصول: https://doaj.org/article/1465840fa9a54ea1934ac0d57780f1cd

المؤلفون: Zihan Zhou, Jie Huang, Ming Ding, Jing Huang, Ting Wu, Qun Wang, Shuhua Han, Yuan Lu

المصدر: Respiratory Medicine Case Reports, Vol 48, Iss , Pp 101953- (2024)

مصطلحات موضوعية: Epidermal growth factor receptor (EGFR), Non-small cell lung cancer (NSCLC), Afatinib, L861Q, G719X, Compound mutations, Diseases of the respiratory system, RC705-779

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221300712300148X; https://doaj.org/toc/2213-0071

URL الوصول: https://doaj.org/article/aee6ad8bab2547aba999dfce7d3acc01

المؤلفون: DING Ning, ZHOU Jiebai

المصدر: 陆军军医大学学报, Vol 44, Iss 24, Pp 2493-2499 (2022)

مصطلحات موضوعية: alk-tki-resistance mechanism, compound mutations, drug resistance, rebiopsy, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://aammt.tmmu.edu.cn/Upload/rhtml/202209192.htm; https://doaj.org/toc/2097-0927

URL الوصول: https://doaj.org/article/dfb85b4566c24718bd1f46e64f621960

المؤلفون: Yunhua Huang, Linlin Li, Liqiu Pan, Xiaoting Ling, Chenghan Wang, Chaoyu Huang, Yifang Huang

المصدر: Frontiers in Genetics, Vol 14 (2023)

مصطلحات موضوعية: non-syndromic enlarged vestibular aqueduct, SLC26A4, compound mutations, sensorineural hearing loss, pendrin, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2023.1240701/full; https://doaj.org/toc/1664-8021

URL الوصول: https://doaj.org/article/7e7b6e458c6142188daf1cd76cec1623

المؤلفون: Waleed Kian, Bilal Krayim, Hadel Alsana, Betsy Giles, Ofer Purim, Wafeek Alguayn, Farouq Alguayn, Nir Peled, Laila C. Roisman

المصدر: Frontiers in Oncology, Vol 13 (2023)

مصطلحات موضوعية: EGFR, L833V, V834L, compound mutations, lung cancer, CEP85L-ROS1 fusion, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1124949/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/6868af2f25d84da6a90cf2804406ca92

المؤلفون: Bar, Jair, Peled, Nir, Schokrpur, Shiruyeh, Wolner, Mirjana, Rotem, Ofer, Girard, Nicolas, Aboubakar Nana, Frank, Derijcke, Sofie, Kian, Waleed, Patel, Sandip, Gantz-Sorotsky, Hadas, Zer, Alona, Moskovitz, Mor, Metro, Giulio, Rottenberg, Yakir, Calles, Antonio, Hochmair, Maximilian, Cuppens, Kristof, Decoster, Lynn, Reck, Martin, Limon, Dror, Rodriguez, Estelamari, Astaras, Christoforos, Bettini, Adrienne, Häfliger, Simon, Addeo, Alfredo

المساهمون: UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - SSS/DDUV/GECE - Génétique cellulaire, UCL - (SLuc) Service de pneumologie

المصدر: Journal of thoracic oncology, Vol. 18, no. 2, p. 169-180 (2023)

مصطلحات موضوعية: Compound mutations, Metastatic, NSCLC, Uncommon EGFR mutation

Relation: boreal:268022; http://hdl.handle.net/2078.1/268022; info:pmid/36307041; urn:ISSN:1556-0864; urn:EISSN:1556-1380

الاتاحة: http://hdl.handle.net/2078.1/268022
https://doi.org/10.1016/j.jtho.2022.10.004

المؤلفون: Junichiro Yuda, Nobuhiko Yamauchi, Ayumi Kuzume, Yong-Mei Guo, Nobue Sato, Yosuke Minami

المصدر: Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-6 (2021)

مصطلحات موضوعية: Relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia, Blinatumomab, Ponatinib, Tyrosine kinase inhibitor, BCR–ABL compound mutations, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1752-1947

URL الوصول: https://doaj.org/article/597cbb906d174e52b7970f3b4728ed99

المؤلفون: Pascal Wang, Emmanuelle Fabre, Antoine Martin, Kader Chouahnia, Ambre Benabadji, Lise Matton, Boris Duchemann

المصدر: Frontiers in Oncology, Vol 12 (2022)

مصطلحات موضوعية: NSCLC, uncommon mutation, exon 18, tyrosine kinase inhibitor (TKI), compound mutations, EGFR, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.918855/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/3581a5abb8ee400bbf490cc96629ef2f

المؤلفون: James Chih-Hsin Yang, Martin Schuler, Sanjay Popat, Satoru Miura, Keunchil Park, Antonio Passaro, Filippo De Marinis, Flavio Solca, Angela Märten, Edward S. Kim

المصدر: Frontiers in Oncology, Vol 12 (2022)

مصطلحات موضوعية: afatinib, non-small-cell lung cancer, uncommon EGFR mutations, compound mutations, EGFR exon 20 insertions, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.834704/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/06285341cf024f7fb6cee27c5cc600a1

المؤلفون: Pizzutilo, E. G., Agostara, A. G., Oresti, S., Signorelli, D., Stabile, S., Lauricella, C., Motta, V., Amatu, A., Ruggieri, L., Brambilla, M., Occhipinti, M., Proto, C., Giusti, R., Filetti, M., Genova, C., Barletta, G., Gelsomino, F., Bennati, C., Siringo, M., Di Fazio, G. R., Russano, M., Montrone, M., Gariazzo, E., Roca, E., Bordi, P., Delmonte, A., Scimone, A., Belluomini, L., Mazzoni, F., Carta, A., Pelizzari, G., Viscardi, G., Morgillo, F., Gelibter, A., Gori, S., Berardi, R., Cortinovis, D., Ardizzoni, A., Veronese, S. M., Sartore-Bianchi, A., Giannetta, L. G., Cerea, G., Siena, S.

المساهمون: Pizzutilo, E. G., Agostara, A. G., Oresti, S., Signorelli, D., Stabile, S., Lauricella, C., Motta, V., Amatu, A., Ruggieri, L., Brambilla, M., Occhipinti, M., Proto, C., Giusti, R., Filetti, M., Genova, C., Barletta, G., Gelsomino, F., Bennati, C., Siringo, M., Di Fazio, G. R., Russano, M., Montrone, M., Gariazzo, E., Roca, E., Bordi, P., Delmonte, A., Scimone, A., Belluomini, L., Mazzoni, F., Carta, A., Pelizzari, G., Viscardi, G., Morgillo, F., Gelibter, A., Gori, S., Berardi, R., Cortinovis, D., Ardizzoni, A., Veronese, S. M., Sartore-Bianchi, A., Giannetta, L. G., Cerea, G., Siena, S.

مصطلحات موضوعية: atypical EGFR, compound mutations, NSCLC, osimertinib, uncommon EGFR mutations

Relation: info:eu-repo/semantics/altIdentifier/pmid/38878323; info:eu-repo/semantics/altIdentifier/wos/WOS:001257471700001; volume:9; issue:6; firstpage:103592; lastpage:103592; numberofpages:1; journal:ESMO OPEN; https://hdl.handle.net/11562/1140869

الاتاحة: https://hdl.handle.net/11562/1140869
https://doi.org/10.1016/j.esmoop.2024.103592

المؤلفون: Jingwen Jiang, Guang Chen, Jingying Wu, Xinghua Luan, Haiyan Zhou, Xiaoli Liu, Zeyu Zhu, Xiaoxuan Song, Shige Wang, Xiaohang Qian, Juanjuan Du, Xiaojun Huang, Mei Zhang, Wei Xu, Li Cao

المصدر: Frontiers in Genetics, Vol 11 (2020)

مصطلحات موضوعية: Cerebrotendinous xanthomatosis, CYP27A1, clinical features, compound mutations, Chinese, hotspot, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fgene.2020.00682/full; https://doaj.org/toc/1664-8021

URL الوصول: https://doaj.org/article/dc6bf80aaf134ad1888bdf8f047b5232

المؤلفون: Kei Namba, Shuta Tomida, Takehiro Matsubara, Yuta Takahashi, Eisuke Kurihara, Yusuke Ogoshi, Takahiro Yoshioka, Tatsuaki Takeda, Hidejiro Torigoe, Hiroki Sato, Kazuhiko Shien, Hiromasa Yamamoto, Junichi Soh, Kazunori Tsukuda, Shinichi Toyooka

المصدر: BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)

مصطلحات موضوعية: Non-small cell lung cancer, Epidermal growth factor receptor, Compound mutations, Molecular barcoding, Genomic heterogeneity, Patient genotype, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-019-5374-1; https://doaj.org/toc/1471-2407

URL الوصول: https://doaj.org/article/0061557ff09a4c7f96518cb52de7af72

المؤلفون: Xiangyang Yu, Xuewen Zhang, Zichen Zhang, Yongbin Lin, Yingsheng Wen, Yongqiang Chen, Weidong Wang, Lanjun Zhang

المصدر: Cancer Communications, Vol 38, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: EGFR, TKIs, Compound mutations, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40880-018-0321-0; https://doaj.org/toc/2523-3548

URL الوصول: https://doaj.org/article/f9fcef57f6e84c2f81631a42857909c4

المؤلفون: Núñez-Carpintero, Iker, Cirillo, Davide, Valencia, Alfonso

مصطلحات موضوعية: Àrees temàtiques de la UPC::Informàtica::Arquitectura de computadors, High performance computing, Myasthenic Syndromes, Congenital, Neuromuscular diseases, DNA, Genomics, Computational biology, Personalized medicine, Pharmacogenomics, Multilayer network, Network community analysis, Heterozygous compound mutations, Càlcul intensiu (Informàtica), Malalties neuromusculars, ADN, Genòmica, Biologia computacional, Medicina personalitzada, Farmacogenòmica

وصف الملف: 2 p.

Relation: Núñez-Carpintero, I.; Cirillo, D.; Valencia, A. A multilayer network approach to elucidate severity in Congenital Myasthenic Syndromes. A: BSC Severo Ochoa International Doctoral Symposium (6th: 2019: Barcelona). "Book of abstracts". Barcelona: Barcelona Supercomputing Center, 2019, p. 93-94.; http://hdl.handle.net/2117/167770

الاتاحة: http://hdl.handle.net/2117/167770

المؤلفون: Metro, Giulio, Baglivo, Sara, Metelli, Niccolò, Bonaiti, Angelo, Matocci, Roberta, Di Girolamo, Bruna, Mandarano, Martina, Colafigli, Claudia, Bellezza, Guido, Roila, Fausto, Ludovini, Vienna

المساهمون: Metro, Giulio, Baglivo, Sara, Metelli, Niccolò, Bonaiti, Angelo, Matocci, Roberta, Di Girolamo, Bruna, Mandarano, Martina, Colafigli, Claudia, Bellezza, Guido, Roila, Fausto, Ludovini, Vienna

مصطلحات موضوعية: ALK, F1174L, G1202R/F1174V, brain metastases, compound mutations, lorlatinib, non-small cell lung cancer, platinum/pemetrexed

Relation: info:eu-repo/semantics/altIdentifier/pmid/36537289; info:eu-repo/semantics/altIdentifier/wos/WOS:000899337200001; volume:35; issue:6; firstpage:576; lastpage:582; numberofpages:7; journal:JOURNAL OF CHEMOTHERAPY; https://hdl.handle.net/11391/1566157; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85144524712

الاتاحة: https://hdl.handle.net/11391/1566157
https://doi.org/10.1080/1120009X.2022.2157611

المؤلفون: Jair Bar, Nir Peled, Shiruyeh Schokrpur, Mirjana Wolner, Ofer Rotem, Nicolas Girard, Frank Aboubakar Nana, Sofie Derijcke, Waleed Kian, Sandip Patel, Hadas Gantz-Sorotsky, Alona Zer, Mor Moskovitz, Giulio Metro, Yakir Rottenberg, Antonio Calles, Maximilian Hochmair, Kristof Cuppens, Lynn Decoster, Martin Reck, Dror Limon, Estelamari Rodriguez, Christoforos Astaras, Adrienne Bettini, Simon Häfliger, Alfredo Addeo

المساهمون: Calles, Antonio/0000-0002-2547-1947, Cuppens, Kristof/0000-0002-8153-0008, Haefliger, Simon/0000-0002-9721-3314, Bar, Jair, Peled, Nir, Schokrpur, Shiruyeh, Wolner, Mirjana, Rotem, Ofer, Girard, Nicolas, Nana, Frank Aboubakar, Derijcke, Sofie, Kian, Waleed, Patel, Sandip, Gantz-Sorotsky, Hadas, Zer, Alona, Moskovitz, Mor, Metro, Giulio, Rottenberg, Yakir, Calles, Antonio, Hochmair, Maximilian, CUPPENS, Kristof, Decoster, Lynn, Reck, Martin, Limon, Dror, Rodriguez, Estelamari, Astaras, Christoforos, Bettini, Adrienne, Hafliger, Simon, Addeo, Alfredo, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - SSS/DDUV/GECE - Génétique cellulaire, UCL - (SLuc) Service de pneumologie

المصدر: Journal of thoracic oncology, p. [1-12] (2022)

مصطلحات موضوعية: Uncommon EGFR mutation, Pulmonary and Respiratory Medicine, Oncology, Compound mutations, Metastatic, NSCLC, California

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408610bd506d327db28c74d8e74fc464
http://hdl.handle.net/1942/40427

المؤلفون: Yunhua Huang, Linlin Li, Liqiu Pan, Xiaoting Ling, Chenghan Wang, Chaoyu Huang, Yifang Huang

مصطلحات موضوعية: Genetics, Genetic Engineering, Biomarkers, Developmental Genetics (incl. Sex Determination), Epigenetics (incl. Genome Methylation and Epigenomics), Gene Expression (incl. Microarray and other genome-wide approaches), Genome Structure and Regulation, Genomics, Genetically Modified Animals, Livestock Cloning, Gene and Molecular Therapy, non-syndromic enlarged vestibular aqueduct, SLC26A4, compound mutations, sensorineural hearing loss, pendrin

Relation: https://figshare.com/articles/dataset/Table1_Non-syndromic_enlarged_vestibular_aqueduct_caused_by_novel_compound_mutations_of_the_SLC26A4_gene_a_case_report_and_literature_review_docx/24098757

الاتاحة: https://doi.org/10.3389/fgene.2023.1240701.s001
https://figshare.com/articles/dataset/Table1_Non-syndromic_enlarged_vestibular_aqueduct_caused_by_novel_compound_mutations_of_the_SLC26A4_gene_a_case_report_and_literature_review_docx/24098757

المؤلفون: Yosuke Minami, Yong-Mei Guo, Nobuhiko Yamauchi, Ayumi Kuzume, Nobue Sato, Junichiro Yuda

المصدر: Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-6 (2021)
Journal of Medical Case Reports

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, medicine.medical_specialty, Combination therapy, Blinatumomab, medicine.medical_treatment, Tyrosine kinase inhibitor, lcsh:Medicine, Antineoplastic Agents, Case Report, Hematopoietic stem cell transplantation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Maintenance therapy, Acute lymphocytic leukemia, Internal medicine, hemic and lymphatic diseases, Antibodies, Bispecific, medicine, Humans, Philadelphia Chromosome, Protein Kinase Inhibitors, Aged, business.industry, Ponatinib, lcsh:R, Hematopoietic Stem Cell Transplantation, Imidazoles, Imatinib, General Medicine, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Dasatinib, Pyridazines, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia, Female, business, BCR–ABL compound mutations, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36f37d18976331cabe2ff6174e48bbc
https://doaj.org/article/597cbb906d174e52b7970f3b4728ed99

المؤلفون: Martinelli, G, Boissel, N, Chevallier, P, Ottmann, O, Goekbuget, N, Topp, MS, Fielding, AK, Rambaldi, A, Ritchie, EK, Papayannidis, C, Sterling, LR, Benjamin, J, Stein, A

المصدر: Journal of Clinical Oncology , 35 (16) pp. 1795-1802. (2017)

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Oncology, Tyrosine Kinase Inhibitors, Minimal Residual Disease, Stem-Cell Transplantation, Compound Mutations, Resistance, Imatinib, Ponatinib, Chemotherapy, Dasatinib, BCR-ABL1

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/1561712/1/Fielding_jco.2016.69.3531.pdf; https://discovery.ucl.ac.uk/id/eprint/1561712/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/1561712/1/Fielding_jco.2016.69.3531.pdf
https://discovery.ucl.ac.uk/id/eprint/1561712/