المؤلفون: Juan Blanco, Teresa

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

Thesis Advisors: Aloy, Patrick

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Biología de sistemas, Enfermedades complejas, Datos ómicos, Respuesta farmacológica, Efectos secundarios, Systems biology, Complex diseases, Omics data, Drug response, Drug side effects

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/593162

المؤلفون: Isús Díaz, Laura

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

Thesis Advisors: Aloy, Patrick

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Ad hoc ontologies, Complex diseases, Perturbation response, Network biology, Genetic background, Ontologies ad hoc, Malalties complexes, Resposta a pertorbacions, Biologia de xarxes, Rerefons genètic

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/565810

المؤلفون: Spataro, Nino

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

Thesis Advisors: Bosch Fusté, Elena

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Mendelian disorders, Complex diseases, Parkinson's disease, Malalties complexes, Malaltia de Parkinson, Mètodes de col.lapse, Copy number variation (CNVs), Malalties mendelianes, Collapsing methods, Variació en el número de còpies

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/482220

المؤلفون: Tingting Wu, Yu Hu, Liang V. Tang

المصدر: Biomarker Research, Vol 12, Iss 1, Pp 1-29 (2024)

مصطلحات موضوعية: Gene therapy, Polygenic diseases, Complex diseases, CRISPR-CAS9, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2050-7771

URL الوصول: https://doaj.org/article/d83f835ce9d34ae3ad58e0924c1b7bb6

المؤلفون: Iagnocco, AnnaMaria, Lioté, Frédéric, McCarthy, Geraldine, Ramonda, Roberta, Richette, Pascal, Sivera, Francisca, Andrés, Mariano, Cipolletta, Edoardo, Doherty, Michael, Pascual, Eliseo, Perez-Ruiz, Fernando, So, Alexander, Jansen, Tim, Kohler, Minna, Stamp, Lisa, Yinh, Janeth, Adinolfi, Antonella, Arad, Uri, Aung, Thanda, Benillouche, Eva, Bortoluzzi, Alessandra, Dau, Jonathan, Maningding, Ernest, Fang, Meika, Figus, Fabiana, Filippucci, Emilio, Haslett, Janine, Janssen, Matthijs, Kaldas, Marian, Kimoto, Maryann, Leamy, Kelly, Navarro, Geraldine, Sarzi-Puttini, Piercarlo, Scirè, Carlo, Silvagni, Ettore, Sirotti, Silvia, Stack, John, Truong, Linh, Abhishek, Abhishek, Tedeschi, Sara, Pascart, Tristan, Latourte, Augustin, Dalbeth, Nicola, Neogi, Tuhina, Fuller, Amy, Rosenthal, Ann, Becce, Fabio, Bardin, Thomas, Ea, Hang-Korng, Filippou, Georgios, Yokose, Chio, Hendry, Alison, Terkeltaub, Robert, Taylor, William, Choi, Hyon, FitzGerald, John, Xie, Chen

المصدر: Annals of the Rheumatic Diseases. 82(10)

مصطلحات موضوعية: Autoimmune Diseases, Immune Complex Diseases, Immune System Diseases, Humans, United States, Chondrocalcinosis, Rheumatology, Calcium Pyrophosphate, Calcinosis, Syndrome

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2j09q5c0

المؤلفون: Garcia Linares, Carles

المساهمون: University/Department: Universitat de Barcelona. Departament de Genètica

Thesis Advisors: Serra Arenas, Eduard, Grinberg Vaisman, Daniel Raúl

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Malalties complexes, Enfermedades complejas, Complex diseases, Genètica humana, Genética humana, Human genetics, Saccharomyces cerevisiae, Tumors, Tumores, Ciències Experimentals i Matemàtiques

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/97356

المؤلفون: Roberta Giordo, Audra N. Iness, Udhaya Kumar

المصدر: Frontiers in Pharmacology, Vol 16 (2025)

مصطلحات موضوعية: cancer, cell cycle regulation, multidisciplinary approaches, complex diseases, molecular mechanisms, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2025.1554529/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/4c34972b7eca47da9d674a0bb839d0ff

المؤلفون: Sara Palomino-Echeverria, Estefania Huergo, Asier Ortega-Legarreta, Eva M. Uson Raposo, Ferran Aguilar, Carlos de la Peña-Ramirez, Cristina López-Vicario, Carlo Alessandria, Wim Laleman, Alberto Queiroz Farias, Richard Moreau, Javier Fernandez, Vicente Arroyo, Paolo Caraceni, Vincenzo Lagani, Cristina Sánchez-Garrido, Joan Clària, Jesper Tegner, Jonel Trebicka, Narsis A. Kiani, Nuria Planell, Pierre-Emmanuel Rautou, David Gomez-Cabrero

المصدر: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)

مصطلحات موضوعية: Stratification, Clustering, Complex diseases, Cirrhosis, ACLF, Patient heterogeneity, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1479-5876

URL الوصول: https://doaj.org/article/afc33b047ee34914a86a10e0483c2fdb

المؤلفون: Johansson, Åsa, Andreassen, Ole A, Brunak, Søren, Franks, Paul W, Hedman, Harald, Loos, Ruth J F, Meder, Benjamin, Melén, Erik, Wheelock, Craig E, Jacobsson, Bo

المصدر: Journal of Internal Medicine eSSENCE: The e-Science Collaboration EXODIAB: Excellence of Diabetes Research in Sweden EpiHealth: Epidemiology for Health. 294(4):378-396

مصطلحات موضوعية: complex diseases, genetic variations, genomic medicine, GWAS, Molecular profiling, multi omics, polygenic risk score (PRS), precision medicine, Medicin och hälsovetenskap, Klinisk medicin, Neurologi, Medical and Health Sciences, Clinical Medicine, Neurology, Reumatologi och inflammation, Rheumatology and Autoimmunity

URL الوصول: https://lup.lub.lu.se/record/385d682b-1ef2-4f95-8ef1-c57023fc330f
http://dx.doi.org/10.1111/joim.13640

المؤلفون: Zhang, Ying, Barupal, Dinesh K, Fan, Sili, Gao, Bei, Zhu, Chao, Flenniken, Ann M, McKerlie, Colin, Nutter, Lauryl MJ, Lloyd, Kevin C Kent, Fiehn, Oliver

المصدر: Metabolites. 13(8)

مصطلحات موضوعية: Medical Biochemistry and Metabolomics, Analytical Chemistry, Biomedical and Clinical Sciences, Chemical Sciences, Genetics, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, animal models, lipidomics, mass spectrometry, physiology, complex diseases, Biochemistry and Cell Biology, Clinical Sciences, Biochemistry and cell biology, Medical biochemistry and metabolomics, Analytical chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7tk9k3g8
https://escholarship.org/content/qt7tk9k3g8/qt7tk9k3g8.pdf

المؤلفون: Zhao, Huiling, Rasheed, Humaria, Nøst, Therese Haugdahl, Cho, Yoonsu, Liu, Yi, Bhatta, Laxmi, Bhattacharya, Arjun, Initiative, Global Biobank Meta-analysis, Hemani, Gibran, Smith, George Davey, Brumpton, Ben Michael, Zhou, Wei, Neale, Benjamin M, Gaunt, Tom R, Zheng, Jie

المصدر: Cell Genomics. 2(11)

مصطلحات موضوعية: Epidemiology, Biological Sciences, Health Sciences, Genetics, Good Health and Well Being, Global Biobank Meta-analysis Initiative, complex diseases, drug target prioritization, multi-ancestry Mendelian randomization, plasma proteome

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7gx5m65z
https://escholarship.org/content/qt7gx5m65z/qt7gx5m65z.pdf

المؤلفون: Qi Zhao, Zuo-Bin Zhu, Jian Li, Li Zhang, Liang Wang

المصدر: Frontiers in Microbiology, Vol 15 (2024)

مصطلحات موضوعية: human microbiota, complex diseases, data-driven approaches, machine learning, artificial intelligence, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2024.1449474/full; https://doaj.org/toc/1664-302X

URL الوصول: https://doaj.org/article/a9eaa579ebee40709e4f51e9bf8e6b88

المؤلفون: Orlov, Yuriy, Savina, Ekaterina, Turkina, Vasilisa, Anashkina, Anastasia

المساهمون: Morić, Ivana, Đorđević, Valentina

المصدر: 5th Belgrade Bioinformatics Conference

مصطلحات موضوعية: bioinformatics, gene networks, complex diseases, education, online tools

Relation: The study was supported by the Russian Science Foundation (grant 24-24-00563).; www.belbi.bg.ac.rs; https://imagine.imgge.bg.ac.rs/handle/123456789/2715; https://hdl.handle.net/21.15107/rcub_imagine_2715

الاتاحة: https://imagine.imgge.bg.ac.rs/handle/123456789/2715
https://imagine.imgge.bg.ac.rs/bitstream/id/846498/BelBi2024-Book-of-Abstracts_1-16,53,141-142.pdf
https://hdl.handle.net/21.15107/rcub_imagine_2715

المؤلفون: Mačak, Nataša, Đurić, Tamara, Dekleva, Milica, Kuveljić, Jovana, Životić, Ivan, Živković, Maja, Đorđević, Ana

المصدر: 7th Congress of the Serbian genetic society : Book of abstracts

مصطلحات موضوعية: molecular genetics, complex diseases, cardiovascular diseases

Relation: info:eu-repo/grantAgreement/MESTD/inst-2020/200017/RS//; https://vinar.vin.bg.ac.rs/handle/123456789/13828; https://hdl.handle.net/21.15107/rcub_vinar_13828

الاتاحة: https://vinar.vin.bg.ac.rs/handle/123456789/13828
http://vinar.vin.bg.ac.rs/bitstream/id/38603/Gen-6.pdf
https://hdl.handle.net/21.15107/rcub_vinar_13828

المؤلفون: Segun Fatumo, Dassen Sathan, Chaimae Samtal, Itunuoluwa Isewon, Tsaone Tamuhla, Chisom Soremekun, James Jafali, Sumir Panji, Nicki Tiffin, Yasmina Jaufeerally Fakim

المصدر: Genome Medicine, Vol 15, Iss 1, Pp 1-13 (2023)

مصطلحات موضوعية: Polygenic risk scores, Africa, Genetic diversity, Genomic architecture, Complex diseases, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-994X

URL الوصول: https://doaj.org/article/47b31cded7804d7dab44f1398fc35771

المؤلفون: Gabrielė Žukauskaitė, Ingrida Domarkienė, Tautvydas Rančelis, Ingrida Kavaliauskienė, Karolis Baronas, Vaidutis Kučinskas, Laima Ambrozaitytė

المصدر: Genetics and Molecular Biology, Vol 47, Iss 2 (2024)

مصطلحات موضوعية: Allele frequency analysis, complex diseases, effect variants, genotyping, positive selection, protective alleles, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572024000300103&lng=en&tlng=en; http://www.scielo.br/pdf/gmb/v47n2/1415-4757-GMB-47-02-e20230030.pdf; https://doaj.org/toc/1678-4685

URL الوصول: https://doaj.org/article/43bfdab6a1b1459098f2f4cedc275e8a

المؤلفون: Jiang, Yingda, Chiu, Chi-Yang, Yan, Qi, Chen, Wei, Gorin, Michael B, Conley, Yvette P, Lakhal-Chaieb, M’Hamed Lajmi, Cook, Richard J, Amos, Christopher I, Wilson, Alexander F, Bailey-Wilson, Joan E, McMahon, Francis J, Vazquez, Ana I, Yuan, Ao, Zhong, Xiaogang, Xiong, Momiao, Weeks, Daniel E, Fan, Ruzong

المصدر: Journal of the American Statistical Association. 116(534)

مصطلحات موضوعية: Macular Degeneration, Genetics, Aging, Neurodegenerative, Prevention, Eye Disease and Disorders of Vision, Human Genome, 2.1 Biological and endogenous factors, Aetiology, Eye, Age-related macular degeneration, Association study, Complex diseases, Extended pedigree, Generalized functional linear mixed models, Rare variants, Statistics, Econometrics, Demography, Statistics & Probability

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2326w35v

المؤلفون: University of North Carolina, Chapel Hill

المساهمون: Christy Beneri, Assistant Professor of Pediatrics

المصدر: Booster Vaccine Strategy to Improve Serologic Responses to Influenza Vaccination in Children With Rheumatic Diseases and Inflammatory Bowel Disease Who Are Receiving Immunosuppressive Therapies
Walters HM, Pan N, Lehman TJ, Adams A, Huang WT, Sitaras L, Cunningham-Rundles S, Walsh TJ, Toussi SS. A prospective study comparing infection risk and disease activity in children with juvenile idiopathic arthritis treated with and without tumor necrosis factor-alpha inhibitors. Clin Rheumatol. 2015 Mar;34(3):457-64. doi: 10.1007/s10067-014-2779-8. Epub 2014 Sep 18.
Toussi SS, Pan N, Walters HM, Walsh TJ. Infections in children and adolescents with juvenile idiopathic arthritis and inflammatory bowel disease treated with tumor necrosis factor-alpha inhibitors: systematic review of the literature. Clin Infect Dis. 2013 Nov;57(9):1318-30. doi: 10.1093/cid/cit489. Epub 2013 Jul 29.
Carvalho LM, de Paula FE, Silvestre RV, Roberti LR, Arruda E, Mello WA, Ferriani VP. Prospective surveillance study of acute respiratory infections, influenza-like illness and seasonal influenza vaccine in a cohort of juvenile idiopathic arthritis patients. Pediatr Rheumatol Online J. 2013 Mar 7;11:10. doi: 10.1186/1546-0096-11-10. eCollection 2013.
Aikawa NE, Campos LM, Silva CA, Carvalho JF, Saad CG, Trudes G, Duarte A, Miraglia JL, Timenetsky Mdo C, Viana VS, Franca IL, Bonfa E, Pereira RM. Glucocorticoid: major factor for reduced immunogenicity of 2009 influenza A (H1N1) vaccine in patients with juvenile autoimmune rheumatic disease. J Rheumatol. 2012 Jan;39(1):167-73. doi: 10.3899/jrheum.110721. Epub 2011 Nov 15.
Flannery B, Reynolds SB, Blanton L, Santibanez TA, O'Halloran A, Lu PJ, Chen J, Foppa IM, Gargiullo P, Bresee J, Singleton JA, Fry AM. Influenza Vaccine Effectiveness Against Pediatric Deaths: 2010-2014. Pediatrics. 2017 May;139(5):e20164244. doi: 10.1542/peds.2016-4244. Epub 2017 Apr 3.
Ogimi C, Tanaka R, Saitoh A, Oh-Ishi T. Immunogenicity of influenza vaccine in children with pediatric rheumatic diseases receiving immunosuppressive agents. Pediatr Infect Dis J. 2011 Mar;30(3):208-11. doi: 10.1097/INF.0b013e3181f7ce44.
deBruyn J, Fonseca K, Ghosh S, Panaccione R, Gasia MF, Ueno A, Kaplan GG, Seow CH, Wrobel I. Immunogenicity of Influenza Vaccine for Patients with Inflammatory Bowel Disease on Maintenance Infliximab Therapy: A Randomized Trial. Inflamm Bowel Dis. 2016 Mar;22(3):638-47. doi: 10.1097/MIB.0000000000000615.
Cordero E, Roca-Oporto C, Bulnes-Ramos A, Aydillo T, Gavalda J, Moreno A, Torre-Cisneros J, Montejo JM, Fortun J, Munoz P, Sabe N, Farinas MC, Blanes-Julia M, Lopez-Medrano F, Suarez-Benjumea A, Martinez-Atienza J, Rosso-Fernandez C, Perez-Romero P; TRANSGRIPE 1-2 Study Group. Two Doses of Inactivated Influenza Vaccine Improve Immune Response in Solid Organ Transplant Recipients: Results of TRANSGRIPE 1-2, a Randomized Controlled Clinical Trial. Clin Infect Dis. 2017 Apr 1;64(7):829-838. doi: 10.1093/cid/ciw855.

المؤلفون: Jeong-An Gim

المصدر: Life, Vol 14, Iss 6, p 768 (2024)

مصطلحات موضوعية: TCGA, KoGES, DNA methylation, survival rate, complex diseases, Science

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2075-1729/14/6/768; https://doaj.org/toc/2075-1729

URL الوصول: https://doaj.org/article/84063f3db2d14dd8bf64bb031382b983

المؤلفون: Yue Zheng, Xu Sun, Baijie Feng, Kai Kang, Yuqi Yang, Ailin Zhao, Yijun Wu

المصدر: Frontiers in Artificial Intelligence, Vol 7 (2024)

مصطلحات موضوعية: ChatGPT, artificial intelligence, rare and complex diseases, diagnosis, treatment, Electronic computers. Computer science, QA75.5-76.95

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/frai.2024.1338433/full; https://doaj.org/toc/2624-8212

URL الوصول: https://doaj.org/article/dc87d0aa010b42f8b08db295bebe0214