المؤلفون: Smith, EJ, Farshim, PP, Flomen, R, Jones, ST, McAteer, SJ, Deverman, BE, Gradinaru, V, Bates, GP

المصدر: Brain Communications , 3 (2) (2021)

مصطلحات موضوعية: Gene therapy, AAV-PHP viruses, CNS transduction, high-content imaging, Ly6a inbred strain variants

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10129972/1/Bates_Use%20of%20high-content%20imaging%20to%20quantify%20transduction%20of%20AAV-PHP%20viruses%20in%20the%20brain%20following%20systemic%20delivery_VoR.pdf; https://discovery.ucl.ac.uk/id/eprint/10129972/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10129972/1/Bates_Use%20of%20high-content%20imaging%20to%20quantify%20transduction%20of%20AAV-PHP%20viruses%20in%20the%20brain%20following%20systemic%20delivery_VoR.pdf
https://discovery.ucl.ac.uk/id/eprint/10129972/

المؤلفون: Blessing, D., Vachey, G., Pythoud, C., Rey, M., Padrun, V., Wurm, F.M., Schneider, B.L., Déglon, N.

المصدر: Molecular therapy. Methods & clinical development, vol. 13, pp. 14-26

مصطلحات موضوعية: AAV8, AAV9, CNS transduction, adeno-associated virus, immune affinity chromatography, orbitally shaken bioreactors, suspension HEK293 cells, transient transfection

وصف الملف: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/30591923; info:eu-repo/semantics/altIdentifier/pissn/2329-0501; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_29064F6BCC174; https://serval.unil.ch/notice/serval:BIB_29064F6BCC17; https://serval.unil.ch/resource/serval:BIB_29064F6BCC17.P001/REF.pdf

الاتاحة: https://serval.unil.ch/notice/serval:BIB_29064F6BCC17
https://doi.org/10.1016/j.omtm.2018.11.004
https://serval.unil.ch/resource/serval:BIB_29064F6BCC17.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_29064F6BCC174

المؤلفون: Batista, Ana Rita, King, Oliver D., Reardon, Christopher P., Davis, Crystal, Shankaracharya, FNU, Philip, Vivek, Gray-Edwards, Heather L, Aronin, Neil, Lutz, Cathleen, Landers, John E, Sena-Esteves, Miguel

المساهمون: RNA Therapeutics Institute, Department of Radiology, Horae Gene Therapy Center, Department of Neurology

المصدر: Human gene therapy ; 31 ; 1-2 ; 90-102

مصطلحات موضوعية: Animals, Antigens, Ly, Blood-Brain Barrier, Central Nervous System, Dependovirus, Endothelium, Vascular, Female, Gene Expression, Gene Transfer Techniques, Genes, Reporter, Genetic Vectors, Genotype, Male, Membrane Proteins, Mice, Transgenic, Quantitative Trait Loci, Species Specificity, Transduction, Genetic, AAV-PHP.B, CNS transduction, Ly6a, blood–brain barrier, mouse genetics, Genetics and Genomics, Nervous System

Relation: View article in PubMed; https://doi.org/10.1089/hum.2019.186; Batista AR, King OD, Reardon CP, Davis C, Shankaracharya, Philip V, Gray-Edwards H, Aronin N, Lutz C, Landers J, Sena-Esteves M. Ly6a Differential Expression in Blood-Brain Barrier Is Responsible for Strain Specific Central Nervous System Transduction Profile of AAV-PHP.B. Hum Gene Ther. 2020 Jan;31(1-2):90-102. doi:10.1089/hum.2019.186. Epub 2019 Dec 13. PMID: 31696742.; http://hdl.handle.net/20.500.14038/29846; https://escholarship.umassmed.edu/faculty_pubs/2052; faculty_pubs/2052

الاتاحة: https://doi.org/10.1089/hum.2019.186
https://hdl.handle.net/20.500.14038/29846
https://escholarship.umassmed.edu/faculty_pubs/2052

المؤلفون: Pamela P. Farshim, Rachel Flomen, Gillian P. Bates, Benjamin E. Deverman, Edward J Smith, Sean J McAteer, Viviana Gradinaru, Samuel T Jones

المصدر: Brain Communications

مصطلحات موضوعية: 0301 basic medicine, high-content imaging, AAV-PHP viruses, Hippocampus, Immunofluorescence, Blood–brain barrier, Green fluorescent protein, 03 medical and health sciences, Transduction (genetics), 0302 clinical medicine, Cortex (anatomy), medicine, Tropism, CNS transduction, biology, medicine.diagnostic_test, AcademicSubjects/SCI01870, General Engineering, gene therapy, Cell biology, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Original Article, AcademicSubjects/MED00310, Ly6a inbred strain variants, NeuN, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a455cfe0359001ce4f571a8183fed2be
https://resolver.caltech.edu/CaltechAUTHORS:20210629-201655221

المؤلفون: Bernard L. Schneider, Daniel Blessing, Maria Rey, Catherine Pythoud, Vivianne Padrun, Nicole Déglon, Gabriel Vachey, Florian M. Wurm

المصدر: Molecular therapy. Methods & clinical development, vol. 13, pp. 14-26
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss, Pp 14-26 (2019)

مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, viral vectors, purification, Genetic enhancement, viruses, mammalian-cells, serotype 8, high-titer, adeno-associated virus, medicine.disease_cause, Virus, Article, 03 medical and health sciences, Transduction (genetics), gene-transfer, 0302 clinical medicine, expression, Genetics, medicine, orbitally shaken bioreactors, lcsh:QH573-671, Molecular Biology, Adeno-associated virus, CNS transduction, Chemistry, lcsh:Cytology, HEK 293 cells, Transfection, serum-free production, suspension HEK293 cells, Cell biology, AAV8, AAV9, immune affinity chromatography, transient transfection, lcsh:Genetics, 030104 developmental biology, recombinant-adenoassociated-virus, Cell culture, 030220 oncology & carcinogenesis, Molecular Medicine, Nuclear localization sequence

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e2f29500e6d217fbe465cc0c905352
https://serval.unil.ch/resource/serval:BIB_29064F6BCC17.P001/REF.pdf