نتائج البحث - "CHROMOSOMAL TRANSLOCATIONS"

Relation: The authors thank all patients and their families, physicians, and study teams at the sites for their participation and great contributions to this study. They especially thank Emily Holmes, Kerstin Loeschke, Alana Hoenig, Johanna Wesselmann, Lisa Engel, Verena Bonigut, Marina Stockem, Dana Engelhardt, Katharina Loehers, and Anne Westermann, who worked as project managers; Florian Drey, Ronald D'Brot, Dilara Celik, Joern Harrandt, Viktoria Monar, Uyen Nguyen, Anna Schlo beta nagel, Johannes Poeppinghaus, Michael Verhuelsdonk, Annette Niederhausen, Irene Prei beta ler-Stodden, Olga Korf, Jan-Erik Mittler, Henrik Gerwin, Alwina Flock, Sally Huggins, Anna Wetzel, and Giovanna Gelmi, who worked as data managers; and Sabine Frohs, Tanja Annolleck, Berit Falkowski and Christina Rhein, who worked as safety managers in the GAIA trial. The trial was sponsored by the German CLL Study Group with financial support and study drug provision from Roche, AbbVie, and Janssen. This analysis was partly supported by a Dutch Cancer Foundation grant (Coherent: 13650/2021-Infra).; RIS: urn:3CA692DB00D935E6B4049C472DE04103; http://hdl.handle.net/10138/575306; 85161324651; 001058567800001

الاتاحة: http://hdl.handle.net/10138/575306

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5

Academic Journal

Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations

المؤلفون: Sánchez C., Héctor M, Bennett, Jared B, Wu, Sean L, Rašić, Gordana, Akbari, Omar S, Marshall, John M

المصدر: BMC Biology. 18(1)

URL الوصول: https://escholarship.org/uc/item/1hm726kp

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6

Conference

A new role for FET oncogonic fusions in the regulation of alternative splicing

المؤلفون: Ongena, Loïc, Lucarelli, Eva, Bruyr, Jonathan, Dequiedt, Franck

المصدر: EMBL Symposium: The complex life of RNA, Heidelberg, Germany [DE], 12/10/2022 - 15/10/2022

مصطلحات موضوعية: FET proteins, oncogenic fusions, FET fusions, chromosomal translocations, sarcomas, alternative splicing, post-transcriptional gene regulation, aberrant transcription factors, Life sciences, Genetics & genetic processes, Biochemistry, biophysics & molecular biology, Human health sciences, Oncology, Sciences du vivant, Génétique & processus génétiques, Biochimie, biophysique & biologie moléculaire, Sciences de la santé humaine, Oncologie

URL الوصول: https://orbi.uliege.be/handle/2268/296240

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7

Academic Journal

T-CAST: An optimized CAST-Seq pipeline for TALEN confirms superior safety and efficacy of obligate-heterodimeric scaffolds

المؤلفون: Manuel Rhiel, Kerstin Geiger, Geoffroy Andrieux, Julia Rositzka, Melanie Boerries, Toni Cathomen, Tatjana I. Cornu

المصدر: Frontiers in Genome Editing, Vol 5 (2023)

مصطلحات موضوعية: TALEN, designer nuclease, chromosomal translocations, off-target effects, FokI, preclinical risk assessment, Biotechnology, TP248.13-248.65, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgeed.2023.1130736/full; https://doaj.org/toc/2673-3439

URL الوصول: https://doaj.org/article/cdd565ffee514bbdabc0f8daa0adbfe8

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8

Academic Journal

Twenty-two years later: consistent dose estimation of an accidental overexposure by retrospective biological dosimetry

المؤلفون: Martinez Guerrero, Juan, Gregoire, Eric, Fernandez, Pascale, Dugue, Delphine, Jikia, D, Gruel, Gaëtan

المساهمون: Laboratoire de Radiobiologie des expositions accidentelles (IRSN/PSE-SANTE/SERAMED/LRAcc), Service de recherche en radiobiologie et en médecine régénérative (IRSN/PSE-SANTE/SERAMED), Institut de Radioprotection et de Sûreté Nucléaire (IRSN)-Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Tbilisi State Medical University

المصدر: ISSN: 0144-8420.

مصطلحات موضوعية: Retrospective biological dosimetry, FISH, Cytogenetics, Chromosomal translocations, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/37721056; irsn-04246048; https://irsn.hal.science/irsn-04246048; https://irsn.hal.science/irsn-04246048/document; https://irsn.hal.science/irsn-04246048/file/Author_version_JMG.pdf; PUBMED: 37721056

الاتاحة: https://irsn.hal.science/irsn-04246048
https://irsn.hal.science/irsn-04246048/document
https://irsn.hal.science/irsn-04246048/file/Author_version_JMG.pdf
https://doi.org/10.1093/rpd/ncac260

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9

Dissertation/ Thesis

Impact of Chromosomal Translocations (CTs) on reproductive isolation and fitness in natural yeast isolates

المؤلفون: Almutawa, Qamar E. B. A.

المساهمون: O'Keefe, Raymond, Delneri, Daniela

مصطلحات موضوعية: 572.8, Chromosomal Translocations

URL الوصول: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.706258

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10

Academic Journal

KANK1-NTRK3 fusions define a subset of BRAF mutation negative renal metanephric adenomas

المؤلفون: Aida Catic, Amina Kurtovic-Kozaric, Ardis Sophian, Lech Mazur, Faruk Skenderi, Ondrej Hes, Stephen Rohan, Dinesh Rakheja, Jillene Kogan, Michael R. Pins

المصدر: BMC Medical Genetics, Vol 21, Iss 1, Pp 1-9 (2020)

مصطلحات موضوعية: Metanephric adenoma, Cytogenetics, Chromosomal translocations, KANK1-NTRK3 fusion, BRAF V600E, Internal medicine, RC31-1245, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12881-020-01143-6; https://doaj.org/toc/1471-2350

URL الوصول: https://doaj.org/article/b3fe441e37844186ba41d8dd9a9edb28

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11

Academic Journal

A pipeline for complete characterization of complex germline rearrangements from long DNA reads

المؤلفون: Satomi Mitsuhashi, Sachiko Ohori, Kazutaka Katoh, Martin C. Frith, Naomichi Matsumoto

المصدر: Genome Medicine, Vol 12, Iss 1, Pp 1-17 (2020)

مصطلحات موضوعية: Long read sequencing, Chromosomal translocations/rearrangements, Chromothripsis, Structural variation, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13073-020-00762-1; https://doaj.org/toc/1756-994X

URL الوصول: https://doaj.org/article/2364849c6ba24efbbb696e2dba1b8e82

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12

Academic Journal

Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations

المؤلفون: Héctor M. Sánchez C., Jared B. Bennett, Sean L. Wu, Gordana Rašić, Omar S. Akbari, John M. Marshall

المصدر: BMC Biology, Vol 18, Iss 1, Pp 1-14 (2020)

مصطلحات موضوعية: Chromosomal translocations, Underdominance, Metapopulation, Population dynamics, Population replacement, Biosafety, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12915-020-0759-9; https://doaj.org/toc/1741-7007

URL الوصول: https://doaj.org/article/599caa5ef6344e38ada6de3a3249ed29

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13

Academic Journal

Targeted long-read sequencing reveals clonally expanded HBV-associated chromosomal translocations in patients with chronic hepatitis B

المؤلفون: Nicholas van Buuren, Ricardo Ramirez, Cameron Soulette, Vithika Suri, Dong Han, Lindsey May, Scott Turner, P.C. Parvangada, Ross Martin, Henry L.Y. Chan, Patrick Marcellin, Maria Buti, Nam Bui, Neeru Bhardwaj, Anuj Gaggar, Li Li, Hongmei Mo, Becket Feierbach

المصدر: JHEP Reports, Vol 4, Iss 4, Pp 100449- (2022)

مصطلحات موضوعية: Integrated HBV DNA, Chronic HBV, Chromosomal translocations, Clonal expansion, Long-read sequencing, Targeted sequencing, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555922000210; https://doaj.org/toc/2589-5559

URL الوصول: https://doaj.org/article/7c0e8a4518a5459287d37f93000018b5

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14

Academic Journal

Prediction and validation of hematopoietic stem and progenitor cell off-target editing in transplanted rhesus macaques

المساهمون: Yu, Kyung-Rok

مصطلحات موضوعية: CHROMOSOMAL TRANSLOCATIONS, MOUSE MODEL, GENOME, GENE, CRISPR-CAS9, DELIVERY, SEQ, DNA, SPECIFICITY, EXPRESSION, Ca9, CRISPR, error-corrected sequencing, gene editing, gene therapy, Macaque, off-target, translocation

Relation: Molecular Therapy, Vol.30 No.1, pp.209-222; https://hdl.handle.net/10371/179811; 000744579600003; 2-s2.0-85114667768; 154526

الاتاحة: https://hdl.handle.net/10371/179811
https://doi.org/10.1016/j.ymthe.2021.06.016

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15

Academic Journal

Mitsui-7, heat-treated, and nitrogen-doped multi-walled carbon nanotubes elicit genotoxicity in human lung epithelial cells

المصدر: Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-19 (2019)

مصطلحات موضوعية: Carbon nanotubes, Genotoxicity, Chromosomal translocations, Centromere, Aneuploidy, In vitro, Toxicology. Poisons, RA1190-1270, Industrial hygiene. Industrial welfare, HD7260-7780.8

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12989-019-0318-0; https://doaj.org/toc/1743-8977

URL الوصول: https://doaj.org/article/f9dd026adb4f4279af4e27e0eec9316f

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16

Academic Journal

Investigating the Role of KMT2A in Rhabdoid Tumorigenesis Utilizing CRISPRi-Mediated Knockdown

المؤلفون: Morrison, Adelaide L

المصدر: Science University Research Symposium (SURS)

مصطلحات موضوعية: KMT2A, histone methyltransferase, gene regulation, H3K4 methylation, chromosomal translocations, leukemia, Rhabdoid Tumors, CRISPR interference (CRISPRi), sgRNA (single guide RNA), tumor proliferation, Physical Sciences and Mathematics

Relation: https://repository.belmont.edu/surs/185

الاتاحة: https://repository.belmont.edu/surs/185

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17

Academic Journal

A word of caution : T-DNA-associated mutagenesis in plant reproduction research

المؤلفون: Raabe, Karel, Sun, Limin, Schindfessel, Cédric, Honys, David, Geelen, Danny

المصدر: JOURNAL OF EXPERIMENTAL BOTANY ; ISSN: 0022-0957 ; ISSN: 1460-2431

مصطلحات موضوعية: Biology and Life Sciences, Arabidopsis, chromosome, chromosome rearrangement, gametophyte, meiosis, reproduction, T-DNA, translocation, CHROMOSOMAL TRANSLOCATIONS, INSERTION, INTEGRATION, MUTANTS, REARRANGEMENTS, POLLEN, TRANSFORMATION, MUTATIONS, SITES

وصف الملف: application/pdf

Relation: https://biblio.ugent.be/publication/01HYJDZMJEZK26K65M0Q1K4BZJ; http://doi.org/10.1093/jxb/erae114; https://biblio.ugent.be/publication/01HYJDZMJEZK26K65M0Q1K4BZJ/file/01J0TV0ZWZVBX4RVTMK3RHC1QN

الاتاحة: https://biblio.ugent.be/publication/01HYJDZMJEZK26K65M0Q1K4BZJ
http://hdl.handle.net/1854/LU-01HYJDZMJEZK26K65M0Q1K4BZJ
https://doi.org/10.1093/jxb/erae114
https://biblio.ugent.be/publication/01HYJDZMJEZK26K65M0Q1K4BZJ/file/01J0TV0ZWZVBX4RVTMK3RHC1QN

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18

Academic Journal

ZNF521 Enhances MLL-AF9-Dependent Hematopoietic Stem Cell Transformation in Acute Myeloid Leukemias by Altering the Gene Expression Landscape

المؤلفون: Chiarella, Emanuela, Aloisio, Annamaria, Scicchitano, Stefania, Todoerti, Katia, Cosentino, Emanuela G., Lico, Daniela, Neri, Antonino, Amodio, Nicola, Bond, Heather Mandy, Mesuraca, Maria

المصدر: Chiarella , E , Aloisio , A , Scicchitano , S , Todoerti , K , Cosentino , E G , Lico , D , Neri , A , Amodio , N , Bond , H M & Mesuraca , M 2021 , ' ZNF521 Enhances MLL-AF9-Dependent Hematopoietic Stem Cell Transformation in Acute Myeloid Leukemias by Altering the Gene Expression Landscape ' , International Journal of Molecular Sciences , vol. 22 , no. 19 , 10814 . https://doi.org/10.3390/ijms221910814

مصطلحات موضوعية: acute myeloid leukemia (AML), cord blood-derived hematopoietic stem cells (CB-CD34(+)), human zinc finger protein 521 (hZNF521), mixed lineage leukemia gene (MLL) AF9 (MLLT3 or LTG9), fusion gene MLL-AF9, chromosomal translocations, gene expression, LINEAGE COMMITMENT, MOLECULAR SUBTYPES, MLL-AF9, ZFP521, DIFFERENTIATION, PROGRAM, TRANSITION, PROFILES, MII-AF9, PATHWAY