المؤلفون: Christopher A. Cottrell, Kartik Manne, Rui Kong, Shuishu Wang, Tongqing Zhou, Gwo-Yu Chuang, Robert J. Edwards, Rory Henderson, Katarzyna Janowska, Megan Kopp, Bob C. Lin, Mark K. Louder, Adam S. Olia, Reda Rawi, Chen-Hsiang Shen, Justin D. Taft, Jonathan L. Torres, Nelson R. Wu, Baoshan Zhang, Nicole A. Doria-Rose, Myron S. Cohen, Barton F. Haynes, Lawrence Shapiro, Andrew B. Ward, Priyamvada Acharya, John R. Mascola, Peter D. Kwong

المصدر: Cell Reports, Vol 37, Iss 5, Pp 109922- (2021)

مصطلحات موضوعية: antibody-antigen binding, antibody approach angle, CD4 binding site, cryo-EM, glycan conformation, glycan276, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124721013954; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/0dffdf01c46c4651a77c53c885d4f689

المؤلفون: Saunders, Kevin O, Counts, James, Thakur, Bhishem, Stalls, Victoria, Edwards, Robert, Manne, Kartik, Lu, Xiaozhi, Mansouri, Katayoun, Chen, Yue, Parks, Rob, Barr, Maggie, Sutherland, Laura, Bal, Joena, Havill, Nicholas, Chen, Haiyan, Machiele, Emily, Jamieson, Nolan, Hora, Bhavna, Kopp, Megan, Janowska, Katarzyna, Anasti, Kara, Jiang, Chuancang, Van Itallie, Elizabeth, Venkatayogi, Sravani, Eaton, Amanda, Henderson, Rory, Barbosa, Christopher, Alam, S Munir, Santra, Sampa, Weissman, Drew, Moody, M Anthony, Cain, Derek W, Tam, Ying K, Lewis, Mark, Williams, Wilton B, Wiehe, Kevin, Montefiori, David C, Acharya, Priyamvada, Haynes, Barton F

المصدر: Cell ; ISSN:1097-4172 ; Volume:187 ; Issue:1

مصطلحات موضوعية: CD4 binding site, CD4-mimetic antibody, EM polyclonal epitope mapping, EMPEM, HIV vaccine, broadly neutralizing antibodies, cryo-EM, cryo-electron microscopy, rhesus macaques

Relation: https://doi.org/10.1016/j.cell.2023.12.002; https://pubmed.ncbi.nlm.nih.gov/38181743; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10860651/

الاتاحة: https://doi.org/10.1016/j.cell.2023.12.002
https://pubmed.ncbi.nlm.nih.gov/38181743
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10860651/

المؤلفون: Schommers, Philipp, Gruell, Henning, Abernathy, Morgan E., Tran, My-Kim, Dingens, Adam S., Gristick, Harry B., Barnes, Christopher O., Schoofs, Till, Schlotz, Maike, Vanshylla, Kanika, Kreer, Christoph, Weiland, Daniela, Holtick, Udo, Scheid, Christof, Valter, Markus M., van Gils, Marit J., Sanders, Rogier W., Vehreschild, Jörg J., Cornely, Oliver A., Lehmann, Clara, Fätkenheuer, Gerd, Seaman, Michael S., Bloom, Jesse D., Bjorkman, Pamela J., Klein, Florian

المصدر: Cell, 180(3), 471-489, (2020-02-06)

مصطلحات موضوعية: HIV-1, broadly neutralizing antibodies, CD4 binding site, escape mutations, immunotherapy, cryogenic electron microscopy, deep mutational scanning, mutational antigenic profiling, HIV-1 escape restriction, humanized mice

Relation: https://doi.org/10.1016/j.cell.2020.01.010; https://www.ncbi.nlm.nih.gov/pmc/PMC7042716; eprintid:101003

الاتاحة: https://doi.org/10.1016/j.cell.2020.01.010
https://www.ncbi.nlm.nih.gov/pmc/PMC7042716

المؤلفون: Franck P. Dupuy, Sanket Kant, Alexandre Barbé, Jean-Pierre Routy, Julie Bruneau, Bertrand Lebouché, Cécile Tremblay, Marzena Pazgier, Andrés Finzi, Nicole F. Bernard

المصدر: mBio, Vol 10, Iss 6 (2019)

مصطلحات موضوعية: broadly neutralizing antibodies, HIV Envelope, ADCC, ADCC assay, CD4 binding site antibodies, CD4i antibodies, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/5431e290a44f41d0a90a711ffff01921

المؤلفون: Gergiev, Ivelin S., Setliff, Ian

المصدر: https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1006952.

مصطلحات موضوعية: IMMUNODEFICIENCY-VIRUS TYPE-1, CD4 BINDING-SITE, MONOCLONAL-ANTIBODY VRC01, VACCINE EFFICACY, TRANSMEMBRANE PROTEIN, STRUCTURAL BASIS, POINT MUTATION, WEB SERVER, GP41, RESISTANCE

الاتاحة: http://hdl.handle.net/1803/9923

المؤلفون: Concepción Casado, Sara Marrero-Hernández, Daniel Márquez-Arce, María Pernas, Sílvia Marfil, Ferran Borràs-Grañana, Isabel Olivares, Romina Cabrera-Rodríguez, María-Soledad Valera, Laura de Armas-Rillo, Philippe Lemey, Julià Blanco, Agustín Valenzuela-Fernández, Cecilio Lopez-Galíndez

المصدر: mBio, Vol 9, Iss 2 (2018)

مصطلحات موضوعية: CD4 binding, HIV-1, heritability, LTNP-EC, actin-tubulin modifications, cell signaling, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/b9c065f676794e36920b4671b9e28c10

المؤلفون: Richards, KH, Aasa-Chapman, MMI, McKnight, A, Clapham, PR

مصطلحات موضوعية: IMMUNODEFICIENCY-VIRUS TYPE-1, MONOCYTE-DERIVED MACROPHAGES, CENTRAL-NERVOUS-SYSTEM, CD4 BINDING LOOP, LYMPHOID-TISSUES, BRAIN, INFECTION, CCR5, SENSITIVITY, BLOOD

وصف الملف: ? - ?

Relation: RETROVIROLOGY; 48; http://qmro.qmul.ac.uk/xmlui/handle/123456789/30283

الاتاحة: http://qmro.qmul.ac.uk/xmlui/handle/123456789/30283
https://doi.org/10.1186/1742-4690-7-48

المؤلفون: Arakelyan, A, Fitzgerald, W, King, DF, Rogers, P, Cheeseman, HM, Grivel, J-C, Shattock, RJ, Margolis, L

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, HUMAN-IMMUNODEFICIENCY-VIRUS, NEUTRALIZING ANTIBODIES, MONOCLONAL-ANTIBODIES, CD4 BINDING, TYPE-1, INFECTION, TRIMERS, GP120, BROAD, ASSAY

Relation: Scientific Reports; http://hdl.handle.net/10044/1/48426; https://dx.doi.org/10.1038/s41598-017-00935-w

الاتاحة: http://hdl.handle.net/10044/1/48426
https://doi.org/10.1038/s41598-017-00935-w

المؤلفون: Cottrell, C.A., Manne, K., Kong, R., Wang, S., Zhou, T., Chuang, G.-Y., Edwards, R.J., Henderson, R., Janowska, K., Kopp, M., Lin, B.C., Louder, M.K., Olia, A.S., Rawi, R., Shen, C.-H., Taft, J.D., Torres, J.L., Wu, N.R., Zhang, B., Doria-Rose, N.A., Cohen, M.S., Haynes, B.F., Shapiro, L., Ward, A.B., Acharya, P., Mascola, J.R., Kwong, P.D.

المصدر: Cell Reports, 37(5)

مصطلحات موضوعية: antibody-antigen binding, CD4 binding site, cryo-EM, N276, glycan conformation, immunogen design, glycan276, antibody approach angle

Relation: https://cdr.lib.unc.edu/downloads/3t946203h?file=thumbnail; https://cdr.lib.unc.edu/downloads/3t946203h

الاتاحة: https://doi.org/10.17615/va0x-rf17
https://cdr.lib.unc.edu/downloads/3t946203h?file=thumbnail
https://cdr.lib.unc.edu/downloads/3t946203h

المؤلفون: Selhorst Philippe, Grupping Katrijn, Tong Tommy, Crooks Ema T, Martin Loïc, Vanham Guido, Binley James M, Ariën Kevin K

المصدر: Retrovirology, Vol 10, Iss 1, p 12 (2013)

مصطلحات موضوعية: HIV, Entry, CD4 binding site, gp120, Shedding, Inhibition, Immunologic diseases. Allergy, RC581-607

Relation: http://www.retrovirology.com/content/10/1/12; https://doaj.org/toc/1742-4690; https://doaj.org/article/db75d522eb404586854c84ec051fe4bc

الاتاحة: https://doi.org/10.1186/1742-4690-10-12
https://doaj.org/article/db75d522eb404586854c84ec051fe4bc

المؤلفون: Flores, Aida, Quesada, Ernesto

مصطلحات موضوعية: AIDS, Human Immunodeficiency Virus (HIV), HIV entry, Attachment inhibitors, polyanions, carbohydrate-binding agents (CBAs), CD4 binding site, Co-receptor binding site, glycoprotein gp120

Relation: Postprint; http://dx.doi.org/10.2174/0929867311320060002; Current Medicinal Chemistry 20(6) : 751-771 (2013); http://hdl.handle.net/10261/96451

الاتاحة: http://hdl.handle.net/10261/96451
https://doi.org/10.2174/0929867311320060002

المؤلفون: Changze Han, Agnès L. Chenine, Sharon Kirk, Rebekah Sherburn, Adel Ahmed Rashad Ahmed, Marzena Pazgier, Cameron F. Abrams, Amos B. Smith, Jérémie Prévost, William D. Tolbert, Navid Madani, Natasha Gupta Vergara, Brendan Mann, Irwin Chaiken, Gabrielle Gendron-Lepage, Andrés Finzi, Frank Kirchhoff, Halima Medjahed, Hillel Haim, Daria Zoubchenok, Melissa C. Grenier, Althea Gaffney, Beatrice H. Hahn, Joseph Sodroski

المصدر: mBio
mBio, Vol 11, Iss 3 (2020)
mBio, Vol 11, Iss 3, p e00280-20 (2020)

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, viruses, Human immunodeficiency virus (HIV), Druggability, CD4 mimetic, HIV Envelope Protein gp120, medicine.disease_cause, Insert (molecular biology), Biomimetics, CRF01_AE, CD4mc, chemistry.chemical_classification, 0303 health sciences, Thymocytes, Chemistry, virus diseases, QR1-502, 3. Good health, Phe43 cavity, Domain (ring theory), CD4 Antigens, ADCC, Crystallization, Research Article, Protein Binding, Env, Phenylalanine, Binding pocket, Microbiology, CD4 binding site, Host-Microbe Biology, Cell Line, 03 medical and health sciences, Dogs, Protein Domains, Virology, medicine, Animals, Humans, Binding site, 030304 developmental biology, Binding Sites, 030306 microbiology, neutralization, CD4, gp120, HEK293 Cells, Biophysics, HIV-1, Glycoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e825cfe423142340faf17093660b6d65
http://europepmc.org/articles/PMC7251204

المؤلفون: Pawa, Rahul

المصدر: Electronic Thesis and Dissertation Repository

مصطلحات موضوعية: TNF-, Bioinformatics, broadly neutralizing antibodies, transmission, Immunity, Envelope glycoprotein, CD4 binding site, pro-inflammatory, Immunology of Infectious Disease, vaccine, Virology, HIV-1, Transmitted/founder virus, Immunotherapy

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1548::661b9694a2b82337360867ee1d818853
https://ir.lib.uwo.ca/etd/6993

المؤلفون: YASUHIRO eNISHIYAMA, Stephanie A. Planque, Carl V. Hanson, Richard J. Massey, Sudhir ePaul

المصدر: Frontiers in Immunology, Vol 3 (2012)

مصطلحات موضوعية: Vaccine, human immunodeficiency virus, B cell superantigen, catalytic antibody, CD4 binding determinant, neutralizing antibody, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00383/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/7aab7bba8cf649c7bf9f021153ab1e52

المؤلفون: Zhuang Ke, Finzi Andres, Toma Jonathan, Frantzell Arne, Huang Wei, Sodroski Joseph, Cheng-Mayer Cecilia

المصدر: Retrovirology, Vol 9, Iss 1, p 106 (2012)

مصطلحات موضوعية: R5 SHIV, Coreceptor switch, CD4 binding, Macrophage infection, Immunologic diseases. Allergy, RC581-607

Relation: http://www.retrovirology.com/content/9/1/106; https://doaj.org/toc/1742-4690; https://doaj.org/article/4a8264aa043d46fcbca2231ab049786f

الاتاحة: https://doi.org/10.1186/1742-4690-9-106
https://doaj.org/article/4a8264aa043d46fcbca2231ab049786f

المؤلفون: Grupping Katrijn, Selhorst Philippe, Michiels Johan, Vereecken Katleen, Heyndrickx Leo, Kessler Pascal, Vanham Guido, Martin Loïc, Ariën Kevin K

المصدر: Retrovirology, Vol 9, Iss 1, p 36 (2012)

مصطلحات موضوعية: HIV-1, Resistance, Entry inhibitors, CD4 binding site, Entry efficiency, Immunologic diseases. Allergy, RC581-607

Relation: http://www.retrovirology.com/content/9/1/36; https://doaj.org/toc/1742-4690; https://doaj.org/article/715706bc0ca24b4d993f2aea4bc2a0ad

الاتاحة: https://doi.org/10.1186/1742-4690-9-36
https://doaj.org/article/715706bc0ca24b4d993f2aea4bc2a0ad

المؤلفون: Dueñas-Decamp Maria J, O'Connell Olivia J, Corti Davide, Zolla-Pazner Susan, Clapham Paul R

المصدر: Retrovirology, Vol 9, Iss 1, p 9 (2012)

مصطلحات موضوعية: HIV, envelope, gp120, CD4 binding site, neutralization, Immunologic diseases. Allergy, RC581-607

Relation: http://www.retrovirology.com/content/9/1/9; https://doaj.org/toc/1742-4690; https://doaj.org/article/99d2d90bc0f240bb94e3e4e965a8fb46

الاتاحة: https://doi.org/10.1186/1742-4690-9-9
https://doaj.org/article/99d2d90bc0f240bb94e3e4e965a8fb46

المؤلفون: Richards, KH, Aasa-Chapman, MMI, McKnight, A, Clapham, PR

المصدر: Retrovirology , 7 , Article 48. (2010)

مصطلحات موضوعية: Immunodeficiency-virus Type-1, Monocyte-derived macrophages, Central-nervous-system, CD4 binding loop, Lymphoid-tissues, Brain, Infection, CCR5, Sensitivity, Blood

وصف الملف: application/pdf

Relation: https://discovery.ucl.ac.uk/id/eprint/123210/1/Richards_Modulation_of_HIV1_2010_1742-4690-7-48.pdf; https://discovery.ucl.ac.uk/id/eprint/123210/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/123210/1/Richards_Modulation_of_HIV1_2010_1742-4690-7-48.pdf
https://discovery.ucl.ac.uk/id/eprint/123210/

المؤلفون: Hinz, A, Hulsik, DL, Forsman, A, Koh, WWL, Belrhali, H, Gorlani, A, de Haard, H, Weiss, RA, Verrips, T, Weissenhorn, W

المصدر: PLOS ONE , 5 (5) , Article e10482. (2010)

مصطلحات موضوعية: IMMUNODEFICIENCY-VIRUS TYPE-1, HUMAN MONOCLONAL-ANTIBODY, CD4 BINDING-SITE, PROXIMAL EXTERNAL REGION, FUSION INHIBITOR T-20, ENVELOPE GLYCOPROTEIN, SACCHAROMYCES-CEREVISIAE, MEMBRANE-FUSION, HEAVY-CHAIN, GP41

وصف الملف: application/pdf

Relation: https://discovery.ucl.ac.uk/id/eprint/92971/1/92971.pdf; https://discovery.ucl.ac.uk/id/eprint/92971/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/92971/1/92971.pdf
https://discovery.ucl.ac.uk/id/eprint/92971/

المؤلفون: Arnold, Philipp, Himmels, Patricia, Weiß, Svenja, Decker, Tim-Michael, Markl, Jürgen, Gatterdam, Volker, Tampé, Robert, Bartholomäus, Patrick, Dietrich, Ursula, Dürr, Ralf

مصطلحات موضوعية: HIV-1, Soluble gp140 Env, CXCR4, CCR5, Tropism, V3 loop, 3D EM, Single particle analysis, CD4 binding site, Open structure

Relation: http://www.retrovirology.com/content/11/1/42

الاتاحة: http://www.retrovirology.com/content/11/1/42