المؤلفون: Letha Chemmalil, Tanmay Kulkarni, Mathura Raman, Priya Singh, Yueming Qian, Chris Chumsae, Kyle McHugh, Zhuangrong Huang, Eric Hodgman, Michael C. Borys, Julia Ding, Gloria Li, Anthony Leone

المصدر: Engineering in Life Sciences, Vol 25, Iss 1, Pp n/a-n/a (2025)

مصطلحات موضوعية: µSIA, continuous bioprocessing, FIA labs, monoclonal antibody (mAb), process analytical technology (PAT), quality by design (QbD), Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1618-0240; https://doaj.org/toc/1618-2863

URL الوصول: https://doaj.org/article/a1060ecacf5942e7ad13e4f90f7f926f

المؤلفون: Adam J. Rish, Zhuangrong Huang, Khandaker Siddiquee, Jianlin Xu, Carl A. Anderson, Michael C. Borys, Anurag Khetan

المصدر: Processes; Volume 11; Issue 1; Pages: 223

مصطلحات موضوعية: partial least-squares regression (PLSR), variable importance metric, afucosylation, variable importance in projection (VIP) scores, selectivity ratio (SR), significance multivariate correlation (sMC), monoclonal antibodies, cell culture

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/pr11010223

الاتاحة: https://doi.org/10.3390/pr11010223

المؤلفون: Jianlin Xu, Jianfa Ou, Kyle P. McHugh, Michael C. Borys, Anurag Khetan

المصدر: mAbs, Vol 14, Iss 1 (2022)

مصطلحات موضوعية: Process characterization (PC), process performance qualification (PPQ), in-process control (IPC), Chinese hamster ovary (CHO) cell culture platform, scale-down model (SDM), design of experiment (DOE), Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/f6b90d57fb154df5a121da03dc249e1e

المؤلفون: Caitlin Morris, Ashli Polanco, Andrew Yongky, Jianlin Xu, Zhuangrong Huang, Jia Zhao, Kevin S. McFarland, Seoyoung Park, Bethanne Warrack, Michael Reily, Michael C. Borys, Zhengjian Li, Seongkyu Yoon

المصدر: Bioresources and Bioprocessing, Vol 7, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Metabolomics, Multivariate data analysis, Titer improvement, Feed media optimization, Technology, Chemical technology, TP1-1185, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40643-020-00318-6; https://doaj.org/toc/2197-4365

URL الوصول: https://doaj.org/article/e723f749644b4b40bb36b7119e45666a

المؤلفون: Jianlin Xu, Matthew S. Rehmann, Mengmeng Xu, Shun Zheng, Charles Hill, Qin He, Michael C. Borys, Zheng Jian Li

المصدر: Bioresources and Bioprocessing, Vol 7, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: Fed-batch platform, Process intensification, Monoclonal antibody manufacturing, Perfusion N-1, Chinese hamster ovary cells, Technology, Chemical technology, TP1-1185, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40643-020-00304-y; https://doaj.org/toc/2197-4365

URL الوصول: https://doaj.org/article/775ee38739c642cc9ba11407c734f826

المؤلفون: Emily S. C. Rittershaus, Matthew S. Rehmann, Jianlin Xu, Qin He, Charles Hill, Jeffrey Swanberg, Michael C. Borys, Zheng-Jian Li, Anurag Khetan

المصدر: Bioengineering; Volume 9; Issue 4; Pages: 128

مصطلحات موضوعية: perfusion N-1, process intensification, capacitance, process analytical technologies (PAT), cell-specific perfusion rate (CSPR), platform, scale-up, in-line probe, monoclonal antibody (mAb), Chinese hamster ovary (CHO)

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/bioengineering9040128

الاتاحة: https://doi.org/10.3390/bioengineering9040128

المؤلفون: Zhuangrong Huang, Jianlin Xu, Jun Tian, Kathryn L. Aron, Yueming Qian, Michael C. Borys, Zhengjian Li, Girish Pendse

المصدر: Processes; Volume 10; Issue 3; Pages: 533

مصطلحات موضوعية: transcriptomics, pathway analysis, rosmarinic acid, CHO cell, antioxidants, antibody titer improvement

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biological Processes and Systems; https://dx.doi.org/10.3390/pr10030533

الاتاحة: https://doi.org/10.3390/pr10030533

المؤلفون: Qin He, Matthew S. Rehmann, Jun Tian, Jianlin Xu, Luzmary Sabino, Erik Vandermark, Ziev Basson, Iris Po, Kathleen Bierilo, Gabi Tremml, Giovanni Rizzi, Erik F. Langsdorf, Nan-Xin Qian, Michael C. Borys, Anurag Khetan, Zheng-Jian Li

المصدر: Bioengineering; Volume 9; Issue 4; Pages: 173

مصطلحات موضوعية: re-cloning, titer, biologics manufacturing, Chinese hamster ovary cells, cell culture platform

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/bioengineering9040173

الاتاحة: https://doi.org/10.3390/bioengineering9040173

المؤلفون: Qin He, Jianlin Xu, Erik Vandermark, Jun Tian, Yueming Qian, Cynthia Chelius, Jongchan Lee, Michael C. Borys, Zheng Jian Li, Girish Pendse

المصدر: Data in Brief, Vol 39, Iss , Pp 107491- (2021)

مصطلحات موضوعية: CHO cell culture, High-throughput screening, Rosmarinic acid, Monoclonal antibody titer, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352340921007721; https://doaj.org/toc/2352-3409

URL الوصول: https://doaj.org/article/0d07d6fd26134ab696ee55df8a686e52

المؤلفون: Steven W. Sowa, Yueming Qian, Kathryn L. Aron, Ping Xu, Erik Langsdorf, Bethanne Warrack, Nelly Aranibar, Gabi Tremml, Jianlin Xu, Duncan McVey, Michael Reily, Anurag Khetan, Michael C. Borys, Zheng Jian Li

المصدر: Data in Brief, Vol 33, Iss , Pp 106591- (2020)

مصطلحات موضوعية: CHO cells, Metabolomics, Cell aging, Genetic instability, Antibody Production, Product quality, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352340920314724; https://doaj.org/toc/2352-3409

URL الوصول: https://doaj.org/article/542fd1b1e063445a8be941eb848a5c5d

المؤلفون: Jianlin Xu, Xuankuo Xu, Chao Huang, James Angelo, Christopher L. Oliveira, Mengmeng Xu, Xia Xu, Deniz Temel, Julia Ding, Sanchayita Ghose, Michael C. Borys, Zheng Jian Li

المصدر: mAbs, Vol 12, Iss 1 (2020)

مصطلحات موضوعية: Process intensification, N-1 perfusion, multi-column chromatography, integrated pool-less polishing, cost of goods, biomanufacturing, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/a3ee1083918640cc8d2da6b5af970e46

المؤلفون: Adam J. Rish, Khandaker Siddiquee, Zhuangrong Huang, Jianlin Xu, Carl A. Anderson, Michael C. Borys, Anurag Khetan

المصدر: Biotechnology Journal.

مصطلحات موضوعية: Molecular Medicine, General Medicine, Applied Microbiology and Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fe67afe68e9992e5d377b56d51efd36e
https://doi.org/10.1002/biot.202200604

المؤلفون: Jianlin Xu, Johanna Santos, Nadine S. Anderson, Michael C. Borys, Girish Pendse, Zheng Jian Li

المصدر: Biotechnology Progress. 38

مصطلحات موضوعية: Cricetulus, Polysaccharides, Cricetinae, Lysine, Cell Culture Techniques, Animals, Antibodies, Monoclonal, CHO Cells, Carboxypeptidase B, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7651626e0b8645903e811779e9d3c6
https://doi.org/10.1002/btpr.3268

المؤلفون: Amanda M Lewis, William D Croughan, Nelly Aranibar, Alison G Lee, Bethanne Warrack, Nicholas R Abu-Absi, Rutva Patel, Barry Drew, Michael C Borys, Michael D Reily, Zheng Jian Li

المصدر: PLoS ONE, Vol 11, Iss 6, p e0157111 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4911072?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/f7824c128d3c42edbdc25a3852fe8552

المؤلفون: Erik Langsdorf, Yueming Qian, Michael D. Reily, Jianlin Xu, Nan-xin Qian, Nelly Aranibar, Zheng Jian Li, Christopher Oliveira, Qin He, Susan Egan, Michael C. Borys, Jun Tian, Bethanne M. Warrack

المصدر: Engineering in Life Sciences

مصطلحات موضوعية: 0106 biological sciences, Environmental Engineering, Research groups, Bioengineering, 01 natural sciences, law.invention, 03 medical and health sciences, law, 010608 biotechnology, Glutamine synthetase, specific productivity, Bioreactor, Gene, Research Articles, 030304 developmental biology, 0303 health sciences, Chemistry, Chinese hamster ovary cell, bioprocessing, methionine sulfoximine (MSX), Robustness (evolution), Cell biology, Cell culture, monoclonal antibody, Recombinant DNA, biologics manufacturing, Biotechnology, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0197726f18c706e85674a324c515ae53
http://europepmc.org/articles/PMC7447880

المؤلفون: Zheng Jian Li, Jianlin Xu, Sanchayita Ghose, Cheng Du, Hangtian Song, Angela Lewandowski, Li Tao, Michael C. Borys

المصدر: Process Biochemistry. 86:127-135

مصطلحات موضوعية: 0106 biological sciences, Drug, 0303 health sciences, genetic structures, Manufacturing process, business.industry, Chemistry, media_common.quotation_subject, Bioengineering, 01 natural sciences, Applied Microbiology and Biotechnology, Biochemistry, Biotechnology, 03 medical and health sciences, Cell culture, 010608 biotechnology, Quality (business), Color formation, business, 030304 developmental biology, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::83efbf67983e49b57bd83a49e171bde2
https://doi.org/10.1016/j.procbio.2019.08.013

المؤلفون: Xuankuo Xu, Anthony J. Cura, Seo-Young Park, Susan Egan, Sanchayita Ghose, Kyongbum Lee, Zheng Jian Li, Michael C. Borys, Mengyuan Zheng, Kathryn L. Aron

المصدر: mAbs
article-version (VoR) Version of Record

مصطلحات موضوعية: 0106 biological sciences, Proteomics, Monoclonal antibody, Proteome, Immunology, CHO Cells, 01 natural sciences, disulfide bond reduction, 03 medical and health sciences, Bioreactors, Cricetulus, Downregulation and upregulation, Stress, Physiological, 010608 biotechnology, Heat shock protein, Cellular stress response, Report, Immunology and Allergy, Animals, Disulfides, Protein Interaction Maps, Heat-Shock Proteins, CHO cell culture, 030304 developmental biology, cellular stress response, 0303 health sciences, Chemistry, Endoplasmic reticulum, Chinese hamster ovary cell, Antibodies, Monoclonal, Endoplasmic Reticulum Stress, Cell biology, Oxidative Stress, Cell culture, heat shock proteins, Glycolysis, Reports

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18682e308bebfc430ff2a3cd021ea6f
https://pubmed.ncbi.nlm.nih.gov/34424810

المؤلفون: Yueming Qian, Erik Vandermark, Qin He, Girish Pendse, Jongchan Lee, Cynthia Chelius, Michael C. Borys, Jun Tian, Zheng Jian Li, Jianlin Xu

المصدر: Data in Brief
Data in Brief, Vol 39, Iss, Pp 107491-(2021)

مصطلحات موضوعية: Science (General), Multidisciplinary, medicine.drug_class, Monoclonal antibody titer, Chinese hamster ovary cell, Rosmarinic acid, High-throughput screening, Computer applications to medicine. Medical informatics, R858-859.7, Monoclonal antibody, Hydrolysate, Q1-390, chemistry.chemical_compound, Chemically defined medium, Titer, chemistry, Cell culture, medicine, Food science, CHO cell culture, Data Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de0372cfa37b29d09557bc9365ae38d
https://pubmed.ncbi.nlm.nih.gov/34712760

المؤلفون: Jianfa Ou, Wanyue Cui, Yuxiang Zhao, Yawen Tang, Alexander Williams, Dhanuka Wasalathanthri, Jianlin Xu, Jongchan Lee, Michael C. Borys, Anurag Khetan

الاتاحة: http://dx.doi.org/10.1002/btpr.3477/v2/response1

المؤلفون: Sen Xu, Itzcoatl A. Pla, Michael C. Borys, Anurag Khetan

المصدر: Biotechnology Progress. 36

مصطلحات موضوعية: 0106 biological sciences, Glycosylation, Cell Culture Techniques, CHO Cells, 01 natural sciences, chemistry.chemical_compound, Cricetulus, N-Glycolylneuraminic acid, Cricetinae, 010608 biotechnology, Animals, Humans, Glycoproteins, chemistry.chemical_classification, Chemistry, Chinese hamster ovary cell, Cell Membrane, Osmolar Concentration, 010401 analytical chemistry, N-Acetylneuraminic Acid, Recombinant Proteins, 0104 chemical sciences, Sialic acid, Cell biology, Cytosol, Cell culture, Neuraminic Acids, Glycoprotein, N-Acetylneuraminic acid, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c43388a69e8bc527e2db25ddeb69cfd
https://doi.org/10.1002/btpr.3038