نتائج البحث - "C A, Broomfield"

1

A Novel Tertiary Pyridostigmine Derivative [3-N,N-Dimethylcarbamyloxy)-1-Methyl-Δ3-Tetrahydropyridine]: Anticholinesterase Properties and Efficacy against Soman

المؤلفون: R. RAY, O. E. CLARK, K. W. FORD, K. R. KNIGHT, L. W. HARRIS, C. A. BROOMFIELD

المصدر: Toxicological Sciences. 16:267-274

مصطلحات موضوعية: Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::423f94c94a360a94305781471d9397d5
https://doi.org/10.1093/toxsci/16.2.267

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2

Suppression of sulfur mustard-increased IL-8 in human keratinocyte cell cultures by serine protease inhibitors: implications for toxicity and medical countermeasures

المؤلفون: F M, Cowan, C A, Broomfield, W J, Smith

المصدر: Cell biology and toxicology. 18(3)

مصطلحات موضوعية: Keratinocytes, Serine Proteinase Inhibitors, Interleukin-8, Mustard Gas, Humans, Chemical Warfare Agents, Animal Testing Alternatives, Tosyllysine Chloromethyl Ketone, Cells, Cultured

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e45f8bc45a8fcf246f786ec3e6f345df
https://pubmed.ncbi.nlm.nih.gov/12083423

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3

Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality

المؤلفون: E G, Duysen, B, Li, W, Xie, L M, Schopfer, R S, Anderson, C A, Broomfield, O, Lockridge

المصدر: The Journal of pharmacology and experimental therapeutics. 299(2)

مصطلحات موضوعية: Atropine, Mice, Knockout, Aging, Behavior, Animal, Hand Strength, Organothiophosphorus Compounds, Muscarinic Antagonists, Motor Activity, Body Temperature, Lethal Dose 50, Vasodilation, Mice, Tremor, Acetylcholinesterase, Animals, Cholinesterases, Tissue Distribution, Chemical Warfare Agents, Cholinesterase Inhibitors, Hair

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::78165ccd4bcb314a39c9a9d89591832c
https://pubmed.ncbi.nlm.nih.gov/11602663

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4

Exposure of human epidermal keratinocyte cell cultures to sulfur mustard promotes binding of complement C1q: implications for toxicity and medical countermeasures

المؤلفون: F M, Cowan, C A, Broomfield, W J, Smith

المصدر: Journal of applied toxicology : JAT. 20

مصطلحات موضوعية: Inflammation, Keratinocytes, Binding Sites, Membrane Glycoproteins, Complement C1q, Cell Culture Techniques, Apoptosis, Receptors, Fc, Receptors, Complement, Mitochondrial Proteins, Blister, Hyaluronan Receptors, Antigens, Surface, Mustard Gas, Humans, Dermatologic Agents, Carrier Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e90c68b2365474c9ef2e3b9d13707aef
https://pubmed.ncbi.nlm.nih.gov/11428648

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5

Response of normal human keratinocytes to sulfur mustard: cytokine release

المؤلفون: C M, Arroyo, R J, Schafer, E M, Kurt, C A, Broomfield, A J, Carmichael

المصدر: Journal of applied toxicology : JAT. 20

مصطلحات موضوعية: Inflammation, Keratinocytes, Blister, Mustard Gas, Cell Culture Techniques, Cytokines, Humans, Enzyme-Linked Immunosorbent Assay, Dermatologic Agents, Biomarkers, Skin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::0bc19c276dd74a8e6afd80f652602b62
https://pubmed.ncbi.nlm.nih.gov/11428645

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6

Sulfur mustard exposure enhances Fc receptor expression on human epidermal keratinocytes in cell culture: implications for toxicity and medical countermeasures

المؤلفون: F M, Cowan, C A, Broomfield, W J, Smith

المصدر: Cell biology and toxicology. 14(4)

مصطلحات موضوعية: Keratinocytes, Epidermal Cells, Mustard Gas, Receptors, IgG, Humans, Chemical Warfare Agents, Cells, Cultured

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::24904940414cfbf473067333898e1c89
https://pubmed.ncbi.nlm.nih.gov/9733281

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7

Temperature effects in cyanolysis using elemental sulfur

المؤلفون: C N, Lieske, C R, Clark, L D, Zoeffel, R L, von Tersch, J R, Lowe, C D, Smith, C A, Broomfield, S I, Baskin, D M, Maxwell

المصدر: Journal of applied toxicology : JAT. 16(2)

مصطلحات موضوعية: Sodium Cyanide, Temperature, Serum Albumin, Bovine, Colloids, Sulfur, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::60a544b918b40c2fcfbcdff031866694
https://pubmed.ncbi.nlm.nih.gov/8935794

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8

Hypothesis for synergistic toxicity of organophosphorus poisoning-induced cholinergic crisis and anaphylactoid reactions

المؤلفون: F M, Cowan, T M, Shih, D E, Lenz, J M, Madsen, C A, Broomfield

المصدر: Journal of applied toxicology : JAT. 16(1)

مصطلحات موضوعية: Organophosphate Poisoning, Organophosphorus Compounds, Autonomic Nervous System Diseases, Parasympathetic Nervous System, Cricetinae, Animals, Drug Synergism, Anaphylaxis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::cc7bc001f86c9ba923958ba3f75f301d
https://pubmed.ncbi.nlm.nih.gov/8821672

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9

Protection by butyrylcholinesterase against organophosphorus poisoning in nonhuman primates

المؤلفون: C A, Broomfield, D M, Maxwell, R P, Solana, C A, Castro, A V, Finger, D E, Lenz

المصدر: The Journal of pharmacology and experimental therapeutics. 259(2)

مصطلحات موضوعية: Lethal Dose 50, Male, Organophosphate Poisoning, Behavior, Animal, Butyrylcholinesterase, Poisoning, Soman, Animals, Learning, Macaca mulatta, Sarin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f8c982f64914c0e5d37e22ff87b65cc6
https://pubmed.ncbi.nlm.nih.gov/1941611

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10

Effect of sulfur exposure on protease activity in human peripheral blood lymphocytes

المؤلفون: F M, Cowan, C A, Broomfield, W J, Smith

المصدر: Cell biology and toxicology. 7(3)

مصطلحات موضوعية: Alkylating Agents, Endopeptidases, Mustard Gas, Humans, Protease Inhibitors, Lymphocytes, DNA Damage, Substrate Specificity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::4545d2f2977ae3af5dca4f767a4cfdb2
https://pubmed.ncbi.nlm.nih.gov/1933515

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11

A novel tertiary pyridostigmine derivative [3-(N,N-dimethylcarbamyloxy)-1-methyl-delta 3-tetrahydropyridine]: anticholinesterase properties and efficacy against soman

المؤلفون: R, Ray, O E, Clark, K W, Ford, K R, Knight, L W, Harris, C A, Broomfield

المصدر: Fundamental and applied toxicology : official journal of the Society of Toxicology. 16(2)

مصطلحات موضوعية: Male, Molecular Structure, Antidotes, Guinea Pigs, Soman, Brain, Rats, Inbred Strains, Rats, Blood-Brain Barrier, Acetylcholinesterase, Animals, Cholinesterase Inhibitors, Rabbits, Pyridostigmine Bromide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e7463bb8a754651e1197fbd0128ddb86
https://pubmed.ncbi.nlm.nih.gov/2055358

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12

Academic Journal

TNF-a expression patterns as potential molecular biomarker for human skin cells exposed to vesicant chemical warfare agents: sulfur mustard (HD) and Lewisite (L).

المؤلفون: C. M. Arroyo, D. L. Burman, D. W. Kahler, M. R. Nelson, C. M. Corun, J. J. Guzman, M. A. Smith, E. D. Purcell, B. E. Hackley, S.-D. Soni, C. A. Broomfield

المصدر: Cell Biology & Toxicology; Nov2004, Vol. 20 Issue 6, p345-359, 15p

مصطلحات موضوعية: CHEMICAL warfare, CELLS, GENE expression, CYTOKINES

13

Academic Journal

Putative role of proteolysis and in³ammatory response in the toxicity of nerve and blister chemical warfare agents: implications for multi-threat medical countermeasures (This article is a U.S. government work and is in the public domain in the U.S.A.)The opinions or assertions contained herein are the private views of the authors and are not to be construed as of¯cial or as re³ecting the views of the Department of the Army or the Department of Defense.)

المؤلفون: F. M. Cowan, C. A. Broomﬁeld, D. E. Lenz, W. J. Smith

المصدر: Journal of Applied Toxicology; May2003, Vol. 23 Issue 3, p177-186, 10p

مصطلحات موضوعية: CHEMICAL warfare agents, PROTEOLYSIS, CHEMICAL warfare, TOXICOLOGY

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