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1Academic Journal
المؤلفون: Heyes, Elizabeth (University of Veterinary Medicine Vienna), Porse, Bo T. (Copenhagen University Hospital / University of Copenhagen), D'Altri, Teresa (Copenhagen University Hospital / University of Copenhagen), Pundhir, Sachin (Copenhagen University Hospital / University of Copenhagen), Rzepa, Edwin (University of Veterinary Medicine Vienna), Schuster, Mikkel B. (Copenhagen University Hospital / University of Copenhagen), Eder, Thomas (University of Veterinary Medicine Vienna), Manhart, Gabriele (University of Veterinary Medicine Vienna), Wilhelmson, Anna S. (Copenhagen University Hospital / University of Copenhagen), Wenzel, Anne (Copenhagen University Hospital / University of Copenhagen), Grebien, Florian (University of Veterinary Medicine Vienna), Haferlach, Torsten (Munich Leukemia Laboratory), Schwaller, Jürg (University Children's Hospital Basel), Meggendorfer, Manja (Munich Leukemia Laboratory), Schoof, Erwin M. (Technical University of Denmark), Woessmann, Jakob (Technical University of Denmark), Gentil, Coline (Copenhagen University Hospital / University of Copenhagen), Frank, Anne-Katrine (Copenhagen University Hospital / University of Copenhagen)
المصدر: Nature Communications 14(1) (2023)
مصطلحات موضوعية: Hematopoietic Stem, C/Ebp-Alpha, Mutations Result, Read Alignment, Gene, Evi1, Aml, Transcription, Reveals, Mouse
وصف الملف: application/pdf
Relation: isPartOf:https://phaidra.vetmeduni.ac.at/o:605[Open Access Publications]; https://phaidra.vetmeduni.ac.at/o:2621
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2Academic Journal
المؤلفون: Madsen, Maria Stahl, Broekema, Marjoleine F., Madsen, Martin Rønn, Koppen, Arjen, Borgman, Anouska, Grawe, Cathrin, Thomsen, Elisabeth G. K., Westland, Denise, Kranendonk, Mariette E. G., Koerkamp, Marian Groot, Hamers, Nicole, Bonvin, Alexandre M. J. J., Pittol, Jose M. Ramos, Natarajan, Kedar Nath, Kersten, Sander, Holstege, Frank C. P., Monajemi, Houshang, van Mil, Saskia W. C., Vermeulen, Michiel, Kragelund, Birthe B., Cassiman, David, Mandrup, Susanne, Kalkhoven, Eric
المصدر: Madsen , M S , Broekema , M F , Madsen , M R , Koppen , A , Borgman , A , Grawe , C , Thomsen , E G K , Westland , D , Kranendonk , M E G , Koerkamp , M G , Hamers , N , Bonvin , A M J J , Pittol , J M R , Natarajan , K N , Kersten , S , Holstege , F C P , Monajemi , H , van Mil , S W C , Vermeulen , M , Kragelund , B B ....
مصطلحات موضوعية: RECEPTOR-GAMMA, LIPOPROTEIN-LIPASE, GENETIC-VARIATION, ZINC-FINGER, C/EBP-ALPHA, BINDING, DNA, TRANSCRIPTION, ELEMENTS, RXR
وصف الملف: application/pdf
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3Dissertation/ Thesis
المؤلفون: Uemasu, Kiyoshi, 上桝, 潔, ウエマス, キヨシ
المساهمون: 伊達, 洋至, 萩原, 正敏, 松田, 道行
مصطلحات موضوعية: COPD, C/EBP-alpha, small airway injury, alveolar attachments, emphysema, LEKTI
وصف الملف: application/pdf; text/html
Degree: 博士(医学) -- Doctor of Medical Science -- 京都大学
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4Academic Journal
المؤلفون: Jeong, Gyeong Han, Cho, Jae-Hyeon, Jo, Cheorun, Park, Seungil, Kim, Seong Bong, Kim, Tae Hoon
المساهمون: Jo, Cheorun
مصطلحات موضوعية: SUPPRESSES ADIPOCYTE DIFFERENTIATION, ALPHA-GLUCOSIDASE, 3T3-L1 CELLS, C/EBP-ALPHA, PLASMA, OLIGOMERIZATION, POLYPHENOLS, STRATEGIES, INHIBITORS, PRODUCTS, hybrid compound, (-)-epigallocatechin gallate, phloroglucinol, dielectric barrier discharge plasma, adipogenesis
Relation: Chemical and Pharmaceutical Bulletin, Vol.68 No.12, pp.1155-1162; https://hdl.handle.net/10371/205860; 000595145900005; 2-s2.0-85097121166; 123199
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5Academic Journal
المؤلفون: Caiment, F., Wolters, J., Smit, E., Schrooders, Y., Kleinjans, J., van den Beucken, T.
المصدر: Caiment , F , Wolters , J , Smit , E , Schrooders , Y , Kleinjans , J & van den Beucken , T 2020 , ' Valproic acid promotes mitochondrial dysfunction in primary human hepatocytes in vitro; impact of C/EBPα-controlled gene expression ' , Archives of Toxicology , vol. 94 , no. 10 , pp. 3463-3473 . https://doi.org/10.1007/s00204-020-02835-x
مصطلحات موضوعية: ccaat/enhancer-binding protein alpha (c/ebp alpha), exposure, glutathione, hepatotoxicity, homeostasis, induced liver steatosis, lentiviral shrna, mechanisms, oxygen consumption, phosphorylation, primary human hepatocytes, rna interference, steatosis, transcription factors, transcriptomics, valproic acid
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6Academic Journal
المؤلفون: Jang, Min Kyung, Kim, Cho Hee, Seong, Je Kyung, Jung, Myeong Ho
المساهمون: Seong, Je Kyung
مصطلحات موضوعية: TRANSCRIPTION FACTORS, GENE-EXPRESSION, ADIPOGENESIS, HYPOXIA, BINDING, FAMILY, Adipocyte differentiation, Activating transcription factor 3 (ATF3), CCAAT/enhancer-binding proteins alpha (C/EBP alpha), Promoter
Relation: Biochemical and Biophysical Research Communications, Vol.421 No.1, pp.38-43; https://hdl.handle.net/10371/207865; 000304501400008; 2-s2.0-84860330664; 116685
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7
المؤلفون: Reckzeh, Kristian, Cammenga, Jörg
المصدر: International Journal of Hematology. 91(4):557-568
مصطلحات موضوعية: differentiation, Myeloid, C/EBP alpha, Transcription factor, AML, Leukemia, Bi-allelic mutation, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Cell- och molekylärbiologi, Medical and Health Sciences, Basic Medicine, Cell and Molecular Biology
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8Academic Journal
المؤلفون: Bradford, Stephen T., Nair, Shalima S., Statham, Aaron L., van Dijk, Susan J., Peters, Timothy J., Anwar, Firoz, French, Hugh J., von Martels, Julius Z. H., Sutcliffe, Brodie, Maddugoda, Madhavi P., Peranec, Michelle, Varinli, Hilal, Arnoldy, Rosanna, Buckley, Michael, Ross, Jason P., Zotenko, Elena, Song, Jenny Z., Stirzaker, Clare, Bauer, Denis C., Qu, Wenjia, Swarbrick, Michael M., Lutgers, Helen L., Lord, Reginald V., Samaras, Katherine, Molloy, Peter L., Clark, Susan J.
المصدر: Bradford , S T , Nair , S S , Statham , A L , van Dijk , S J , Peters , T J , Anwar , F , French , H J , von Martels , J Z H , Sutcliffe , B , Maddugoda , M P , Peranec , M , Varinli , H , Arnoldy , R , Buckley , M , Ross , J P , Zotenko , E , Song , J Z , Stirzaker , C , Bauer , D C , Qu , W , Swarbrick , M M , ....
مصطلحات موضوعية: HUMAN ADIPOSE-TISSUE, BODY-MASS INDEX, EPIGENOMIC ANALYSIS, C/EBP-ALPHA, FAT, OBESITY, METHYLATION, CTBP2, RISK, MECHANISMS
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/b3ee8d95-8caf-4e20-86f2-813af45c6669
https://research.rug.nl/en/publications/b3ee8d95-8caf-4e20-86f2-813af45c6669
https://doi.org/10.1038/s41598-019-45777-w
https://pure.rug.nl/ws/files/91113176/Methylome_and_transcriptome_maps_of_human_visceral_and_subcutaneous_adipocytes_reveal_key_epigenetic_differences_at_developmental_genes.pdf -
9Academic Journal
المؤلفون: Zhou, J, Li, H, Xia, X, Herrera, A, Pollock, N, Reebye, V, Sodergren, MH, Dorman, S, Littman, BH, Doogan, D, Huang, K-W, Habib, R, Blakey, D, Habib, NA, Rossi, JJ
المصدر: 1016 ; 999
مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Biotechnology & Applied Microbiology, Genetics & Heredity, Medicine, Research & Experimental, Research & Experimental Medicine, BINDING-PROTEIN-ALPHA, RAW 264.7 CELLS, NF-KAPPA-B, C/EBP-ALPHA, HEPATOCELLULAR-CARCINOMA, RHEUMATOID-ARTHRITIS, DOWN-REGULATION, EXPRESSION, INFLAMMATION, MOUSE, MTL-CEBPA, anti-inflammation, humanized mice, monocytes, saRNA, small activating RNA, Animals, Anti-Inflammatory Agents, CCAAT-Enhancer-Binding Proteins
Relation: Molecular Therapy; http://hdl.handle.net/10044/1/80680
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10Academic Journal
المؤلفون: Jiazhen Wang, Peipei Wang, Tiantian Zhang, Zhuying Gao, Jing Wang, Mengdie Feng, Rong Yin, Haojian Zhang
مصطلحات موضوعية: ACUTE MYELOGENOUS LEUKEMIA, Acute myeloid leukemia, C/EBP-ALPHA, DNMT3A, GENE-EXPRESSION, Hematology, HEMATOPOIETIC-STEM, INTERLEUKIN-3 RECEPTOR, Leukemia stem cell, Life Sciences & Biomedicine, Maintenance, Molecular mechanisms, OXIDATIVE-PHOSPHORYLATION, RECEPTOR-ALPHA CHAIN, Science & Technology, SELF-RENEWAL, Stemness, TRANSCRIPTION FACTORS
Relation: http://hdl.handle.net/10779/DRO/DU:23797029.v2; https://figshare.com/articles/journal_contribution/Molecular_mechanisms_for_stemness_maintenance_of_acute_myeloid_leukemia_stem_cells/23797029
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11Academic Journal
المؤلفون: Guo, Michael H., Nandakumar, Satish K., Ulirsch, Jacob C., Zekavat, Seyedeh M., Buenrostro, Jason D., Natarajan, Pradeep, Salem, Rany M., Chiarle, Roberto, Mitt, Mario, Kals, Mart, Pärn, Kalle, Fischer, Krista, Milani, Lili, Magi, Reedik, Palta, Priit, Gabriel, Stacey B., Metspalu, Andres, Lander, Eric S., Kathiresan, Sekar, Hirschhorn, Joel N., Esko, Tonu, Sankaran, Vijay G.
المساهمون: Institute for Molecular Medicine Finland, Genomics of Neurological and Neuropsychiatric Disorders
مصطلحات موضوعية: genome sequencing, GWAS, basophils, hematopoiesis, CEBPA, INFLAMMATORY-BOWEL-DISEASE, RARE-VARIANT ASSOCIATION, FETAL-HEMOGLOBIN LEVELS, COPY NUMBER VARIATIONS, BLOOD-CELL TRAITS, WIDE ASSOCIATION, MAST-CELL, GENETIC-VARIATION, C/EBP-ALPHA, PARTITIONING HERITABILITY, Biomedicine
وصف الملف: application/pdf
Relation: We thank members of the V.G.S. and J.N.H. Laboratories, as well as the Estonian Genome Center, and numerous colleagues for valuable comments and discussions. This work was supported by National Institutes of Health Grants R01 DK103794, R33 HL120791 (to V.G.S.), and R01 DK075787 (to J.N.H.). P.P. was funded by the Nordic Information for Action eScience Center by NordForsk (Project 62721). The Estonian Genome Center was supported by the Estonian Research Council (PerMed I; IUT20-60); European Union H2020 Grants 692145, 676550, and 654248; and the European Union through the European Regional Development Fund (GENTRANSMED).; Guo , M H , Nandakumar , S K , Ulirsch , J C , Zekavat , S M , Buenrostro , J D , Natarajan , P , Salem , R M , Chiarle , R , Mitt , M , Kals , M , Pärn , K , Fischer , K , Milani , L , Magi , R , Palta , P , Gabriel , S B , Metspalu , A , Lander , E S , Kathiresan , S , Hirschhorn , J N , Esko , T & Sankaran , V G 2017 , ' Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 114 , no. 3 , pp. E327-E336 . https://doi.org/10.1073/pnas.1619052114; ORCID: /0000-0001-9320-7008/work/30434482; http://hdl.handle.net/10138/232542; 61ab282e-bfde-410f-970c-2208c642a2d4; 85009756476; 000392095800009
الاتاحة: http://hdl.handle.net/10138/232542
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12Academic Journal
المؤلفون: Langabeer, Stephen E., Preston, Lisa, Kelly, Johanna, Goodyer, Matt, Elhassadi, Ezzat, Hayat, Amjad
مصطلحات موضوعية: acute myeloid-leukemia, trans-retinoic acid, complete remission, c/ebp-alpha, mutations, disease, rearrangements, patient, genes, cells
Relation: Case Reports in Hematology; Langabeer, Stephen E. Preston, Lisa; Kelly, Johanna; Goodyer, Matt; Elhassadi, Ezzat; Hayat, Amjad (2017). Molecular profiling: a case of zbtb16-rara acute promyelocytic leukemia. Case Reports in Hematology; 2090-6560,2090-6579; http://hdl.handle.net/10379/12375
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13
المؤلفون: J.C.S. (Jos) Kleinjans, E. Smit, T. van den Beucken, Jarno E J Wolters, Yannick Schrooders, Florian Caiment
المساهمون: RS: GROW - R1 - Prevention, Toxicogenomics, RS: MHeNs - R3 - Neuroscience, Oogheelkunde
المصدر: Archives of Toxicology, 94(10), 3463-3473. Springer
Archives of Toxicologyمصطلحات موضوعية: 0301 basic medicine, HOMEOSTASIS, Steatosis, Health, Toxicology and Mutagenesis, Pharmacology, Toxicology, Transcriptome, rna interference, transcriptomics, 0302 clinical medicine, RNA interference, Gene expression, GLUTATHIONE, Primary human hepatocytes, RNA-Seq, PHOSPHORYLATION, Cells, Cultured, Valproic Acid, General Medicine, Ccaat/enhancer-binding protein alpha (C/EBPα), Mitochondria, Liver, Gene Knockdown Techniques, Phosphorylation, lipids (amino acids, peptides, and proteins), Anticonvulsants, medicine.drug, hepatotoxicity, Oxygen consumption, Lentiviral shRNA, MECHANISMS, 03 medical and health sciences, Molecular Toxicology, valproic acid, transcription factors, medicine, CCAAT-Enhancer-Binding Protein-alpha, Humans, EXPOSURE, INDUCED LIVER STEATOSIS, Transcription factor, Ccaat/enhancer-binding protein alpha (C/EBP alpha), business.industry, medicine.disease, Fatty Liver, Oxygen, 030104 developmental biology, Gene Expression Regulation, Hepatocytes, business, 030217 neurology & neurosurgery, Homeostasis, Biomarkers
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14Academic Journal
المؤلفون: Bachas, Costa, Schuurhuls, Gerrit Jan, Zwaan, C. Michel, van den Heuvel-Eibrink, Marry M., den Boer, Monique L., de Bont, Eveline S. J. M., Kwidama, Zinia J., Reinhardt, Dirk, Creutzig, Ursula, de Haas, Valerie, Kaspers, Gertjan J. L., Cloos, Jacqueline
المصدر: Bachas , C , Schuurhuls , G J , Zwaan , C M , van den Heuvel-Eibrink , M M , den Boer , M L , de Bont , E S J M , Kwidama , Z J , Reinhardt , D , Creutzig , U , de Haas , V , Kaspers , G J L & Cloos , J 2015 , ' Gene Expression Profiles Associated with Pediatric Relapsed AML ' , PLoS ONE , vol. 10 , no. 4 , e0121730 . https://doi.org/10.1371/journal.pone.0121730
مصطلحات موضوعية: ACUTE MYELOID-LEUKEMIA, INTERNATIONAL EXPERT PANEL, C/EBP-ALPHA, INTEGRATIVE ANALYSIS, CLONAL EVOLUTION, DRUG-RESISTANCE, CEBPA MUTATIONS, HIGH-FREQUENCY, 1ST RELAPSE, 10 TRIAL
وصف الملف: application/pdf
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15
المؤلفون: Roya Gasimli, Sunde Yilmaz Susluer, Güray Saydam, Fatma Sogutlu, Tugce Balci Okcanoglu, Cagla Kayabasi, Cigir Biray Avci, Aycan Asik, Cumhur Gündüz, Besra Ozmen Yelken
المصدر: European journal of pharmacology. 910
مصطلحات موضوعية: mTOR inhibitor, Stem-Cells, Resistance, Apoptosis, PI3K, chemistry.chemical_compound, Phosphatidylinositol 3-Kinases, Antineoplastic Combined Chemotherapy Protocols, Kinase Inhibitor, Phosphoinositide-3 Kinase Inhibitors, Stem Cells, TOR Serine-Threonine Kinases, Ponatinib, Chronic myeloid leukemia, Imidazoles, NF-kappa B, Myeloid leukemia, Drug Synergism, Pyridazines, Leukemia, STAT Transcription Factors, Differentiation, Combination, Stem cell, Mitogen-Activated Protein Kinases, Bcr-Abl, Signal Transduction, Cell Survival, Mtor, Morpholines, Leukemia stem cell, Antineoplastic Agents, Inhibitory Concentration 50, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, medicine, Humans, Viability assay, Protein kinase B, Biology, PI3K/AKT/mTOR pathway, Janus Kinases, Pharmacology, medicine.disease, G1 Phase Cell Cycle Checkpoints, chemistry, C/Ebp-Alpha, Purines, Imatinib, Cancer research, K562 Cells, Proto-Oncogene Proteins c-akt, Transcription Factors
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16Academic Journal
المؤلفون: Yelken, Besra Ozmen, Kayabasi, Cagla, Asik, Aycan, Okcanoglu, Tugce Balci, Sogutlu, Fatma, Gasimli, Roya, Susluer, Sunde Yilmaz
مصطلحات موضوعية: Leukemia stem cell, Chronic myeloid leukemia, Ponatinib, PI3K, mTOR inhibitor, C/Ebp-Alpha, Bcr-Abl, Kinase Inhibitor, Stem-Cells, Imatinib, Differentiation, Resistance, Biology, Mtor, Combination
Relation: European Journal Of Pharmacology; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11454/76520; https://doi.org/10.1016/j.ejphar.2021.174446; GASIMLI, Roya/0000-0002-6760-8921; Gunduz, Cumhur/0000-0002-6593-3237; 910
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17Academic Journal
المؤلفون: Keglowich, Laura, Roth, Michael, Philippova, Maria, Resink, Therese, Tjin, Gavin, Oliver, Brian, Lardinois, Didier, Dessus-Babus, Sophie, Gosens, Reinoud, Haack, Katrin Hostettler, Tamm, Michael, Borger, Peter
المصدر: Keglowich , L , Roth , M , Philippova , M , Resink , T , Tjin , G , Oliver , B , Lardinois , D , Dessus-Babus , S , Gosens , R , Haack , K H , Tamm , M & Borger , P 2013 , ' Bronchial smooth muscle cells of asthmatics promote angiogenesis through elevated secretion of CXC-chemokines (ENA-78, GRO-α, and IL-8) ' , PLoS ONE , vol. 8 , no. 12 , e81494 . https://doi.org/10.1371/journal.pone.0081494
مصطلحات موضوعية: IDIOPATHIC PULMONARY-FIBROSIS, INDUCED SPUTUM, HUMAN AIRWAY, C/EBP-ALPHA, EXPRESSION, RECEPTOR, DISEASE, VEGF, RESPONSIVENESS, PROLIFERATION
وصف الملف: application/pdf
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18Academic Journal
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19
المؤلفون: Uemasu, Kiyoshi
المساهمون: 伊達, 洋至, 萩原, 正敏, 松田, 道行
مصطلحات موضوعية: emphysema, LEKTI, small airway injury, COPD, alveolar attachments, C/EBP-alpha
وصف الملف: application/pdf
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20
المؤلفون: Alice P. Sowton, Andrew J. Murray, Simon James Tunster, Erica D. Watson, Ben D. McNally, Nisha Padmanabhan, Julian L. Griffin, Antonio Murgia, Aisha Yusuf
المساهمون: Medical Research Council, Medical Research Council (MRC), Sowton, Alice [0000-0002-3718-7783], Tunster, Simon [0000-0002-2242-9452], Murray, Andrew [0000-0002-0929-9315], Watson, Erica [0000-0003-4496-2271], Apollo - University of Cambridge Repository, Watson, Erica D [0000-0003-4496-2271]
المصدر: Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 23, Iss, Pp-(2020)مصطلحات موضوعية: CE, cholesteryl-ester, LC-MS, liquid chromatography-mass spectrometry, 5-methyl-THF, 5-methyltetrahydofolate, OXPHOS, oxidative phosphorylation, G6pc, glucose 6-phophastase gene, PG, phosphatidylglycerol, 0601 Biochemistry and Cell Biology, Gyg, glycogenin gene, PIP, phosphatidylinositol phosphate(s), Cebpa, CCAAT/enhancer binding protein (C/EBP), alpha gene, chemistry.chemical_compound, Isca1, iron‑sulfur cluster assembly 1 gene, PC, phosphatidylcholine, 0302 clinical medicine, Endocrinology, Nonalcoholic fatty liver disease, One‑carbon metabolism, PA, phosphatidic acid, lcsh:QH301-705.5, 0303 health sciences, lcsh:R5-920, biology, Glycogen, FCCP, p-trifluoromethoxyphenyl hydrazine, 030305 genetics & heredity, SAM, S-adenosylmethionine, Mthfr, methylenetetrahydrofolate reductase gene, Mtr, methionine synthase gene (also MS), PS, phosphatidylserine, 3. Good health, PL, phospholipid, Gsk3, glycogen synthase kinase gene, RIPA, Radioimmunoprecipitation assay, Agl, amylo-alpha-1,6-glucosidase,4-alpha-glucanotransferase gene, Ndufs, NADH:ubiquinone oxidoreductase core subunit (ETS complex I) gene, Liver metabolism, Bhmt, betaine-homocysteine S-methyltransferase gene, Hepatic fuel storage, lcsh:Medicine (General), Gbe1, glycogen branching enzyme 1 gene, Research Paper, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, TAG, triacylglycerol, NASH, non-alcoholic steatohepatitis, Cer, ceramide, PE, phosphatidylethanolamine, PI, phosphatidylinositol, 03 medical and health sciences, Internal medicine, FFA, free fatty acid, Genetics, medicine, JO2, oxygen flux, Glycogen synthase, GSK3A, Molecular Biology, Myc, myelocytomatosis oncogene, 0604 Genetics, Methionine, LPC, lysophosphatidylcholine, SM, sphingomyelin, Ddit3, DNA damage inducible transcript 3 gene, SAH, S-adenosylhomocysteine, Lipid metabolism, (Methionine synthase) reductase, Gys2, glycogen synthase 2 gene, Ugp2, UDP-glucose pyrophophorylase 2 gene, medicine.disease, MTRR, HOAD, 3-hydoxyacyl-CoA dehydrogenase, BCA, bicinchoninic acid, Mtrr, methionine synthase reductase gene (also MSR), chemistry, lcsh:Biology (General), gt, gene-trap, Lipidomics, biology.protein, Mitochondrial function, PAS, periodic acid Schiff, DAG, diacylglycerol, 030217 neurology & neurosurgery, ETS, electron transport system
وصف الملف: application/pdf