المؤلفون: Ulven, Elisabeth Rexen, Quon, Tezz, Sergeev, Eugenia, Barki, Natasja, Brvar, Matjaz, Hudson, Brian D., Dutta, Palash, Hansen, Anders Højgaard, Bielefeldt, Line, Tobin, Andrew B., McKenzie, Christine J., Milligan, Graeme, Ulven, Trond

المصدر: Ulven , E R , Quon , T , Sergeev , E , Barki , N , Brvar , M , Hudson , B D , Dutta , P , Hansen , A H , Bielefeldt , L , Tobin , A B , McKenzie , C J , Milligan , G & Ulven , T 2020 , ' Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators ' , Journal of Medicinal Chemistry , vol. 63 , no. 7 , pp. 3577-3595 . https://doi.org/10.1021/acs.jmedchem.9b02036

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/ee444bec-e44b-451d-8e39-19ef3a09a966

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/ee444bec-e44b-451d-8e39-19ef3a09a966
https://doi.org/10.1021/acs.jmedchem.9b02036
https://findresearcher.sdu.dk/ws/files/170028447/Structure_activity_relationship_studies_of_tetrahydroquinolone_free_fatty_acid_receptor_3_modulators.pdf

المؤلفون: Lückmann, Michael, van der Velden, Wijnand Jacobus C, Oliva-Santiago, Marta, Brvar, Matjaz, Ulven, Trond, Frimurer, Thomas Michael, Karlshøj, Stefanie, Rosenkilde, Mette Marie, Larsen, Olav Ditlevsen

المصدر: Lückmann , M , van der Velden , W J C , Oliva-Santiago , M , Brvar , M , Ulven , T , Frimurer , T M , Karlshøj , S , Rosenkilde , M M & Larsen , O D 2019 , ' Selective Allosteric Modulation of N‑Terminally Cleaved, but Not Full Length CCL3 in CCR1 ' , ACS Pharmacology & Translational Science , vol. 2 , no. 6 , pp. 429-441 . https://doi.org/10.1021/acsptsci.9b00059

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/0e8fc46e-60fc-417e-9482-264fe9d9d409

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/0e8fc46e-60fc-417e-9482-264fe9d9d409
https://doi.org/10.1021/acsptsci.9b00059
https://findresearcher.sdu.dk/ws/files/170261280/Selective_allosteric_modulation_of_N_terminally_cleaved_but_not_full_length_CCL3_in_CCR1.pdf

المؤلفون: Rexen Ulven, Elisabeth, Trauelsen, Mette, Brvar, Matjaz, Lückmann, Michael, Bielefeldt, Line, Jensen, Lisa K.I., Schwartz, Thue W., Frimurer, Thomas M.

المصدر: Rexen Ulven , E , Trauelsen , M , Brvar , M , Lückmann , M , Bielefeldt , L , Jensen , L K I , Schwartz , T W & Frimurer , T M 2018 , ' Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1 ' , Scientific Reports , vol. 8 , 10010 . https://doi.org/10.1038/s41598-018-28263-7

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/7bff92c3-16f7-41ed-b18c-06ed946c71f3

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/7bff92c3-16f7-41ed-b18c-06ed946c71f3
https://doi.org/10.1038/s41598-018-28263-7
https://findresearcher.sdu.dk/ws/files/141831374/Structure_Activity_Investigations_and_Optimisations_of_Non_metabolite_Agonists_for_the_Succinate_Receptor_1.pdf

المؤلفون: Trauelsen, Mette, Rexen Ulven, Elisabeth, Hjorth, Siv A, Brvar, Matjaz, Monaco, Claudia, Frimurer, Thomas M, Schwartz, Thue W

المصدر: Trauelsen , M , Rexen Ulven , E , Hjorth , S A , Brvar , M , Monaco , C , Frimurer , T M & Schwartz , T W 2017 , ' Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91 ' , Cell Metabolism , vol. 6 , no. 12 , pp. 1585-1596 . https://doi.org/10.1016/j.molmet.2017.09.005

مصطلحات موضوعية: Journal Article

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/4a58bffe-5e7d-46f7-b710-1ec8c51a1c4a

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/4a58bffe-5e7d-46f7-b710-1ec8c51a1c4a
https://doi.org/10.1016/j.molmet.2017.09.005
https://findresearcher.sdu.dk/ws/files/134171413/Receptor_structure_based_discovery_of_non_metabolite_agonists_for_the_succinate_receptor_GPR91.pdf

المؤلفون: Karlshøj, Stefanie, Amarandi, Roxana Maria, Larsen, Olav, Daugvilaite, Viktorija, Steen, Anne, Brvar, Matjaz, Pui, Aurel, Frimurer, Thomas Michael, Ulven, Trond, Rosenkilde, Mette Marie

المصدر: Karlshøj , S , Amarandi , R M , Larsen , O , Daugvilaite , V , Steen , A , Brvar , M , Pui , A , Frimurer , T M , Ulven , T & Rosenkilde , M M 2016 , ' Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5) ' , Journal of Biological Chemistry , vol. 291 , no. 52 , pp. 26860-26874 . https://doi.org/10.1074/jbc.M116.740183

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/74fbb963-0295-4684-9280-5eaf001fa42e

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/74fbb963-0295-4684-9280-5eaf001fa42e
https://doi.org/10.1074/jbc.M116.740183
https://findresearcher.sdu.dk/ws/files/124859084/Molecular_Mechanism_of_Action_for_Allosteric_Modulators_and_Agonists_in_CC_chemokine_Receptor_5_CCR5_.pdf

المؤلفون: Jakopin, Ziga, Ilas, Janez, Barancokova, Michaela, Brvar, Matjaz, Tammela, Paivi, Dolenc, Marija Sollner, Tomasic, Tihomir, Kikelj, Danijel

المساهمون: Faculty of Pharmacy, Bioactivity Screening Group, Division of Pharmaceutical Biosciences, Drug Research Program

مصطلحات موضوعية: 1,2,4-Oxadiazoles, DNA gyrase inhibition, Topoisomerase IV inhibition, Antibacterial screening, Computer-aided drug design, ATP-BINDING SITE, TOPOISOMERASE-IV, ANTIBACTERIAL ACTIVITY, PYRROLOPYRIMIDINE INHIBITORS, STAPHYLOCOCCUS-AUREUS, N-PHENYLINDOLAMIDES, IIA TOPOISOMERASES, BUILDING-BLOCKS, BROAD-SPECTRUM, B GYRB, Pharmacy

وصف الملف: application/pdf

Relation: SUOMEN AKATEMIA; 277001; This work was supported by the Slovenian Research Agency (Grant No. P1-0208), by the Academy of Finland (Grant No. 277001 and 284477) and by the EU FP7 Project MAREX: Exploring Marine Resources for Bioactive Compounds: from Discovery to Sustainable Production and Industrial Applications (Project No. FP7-KBBE2009-3-245137). The authors thank Dr. Dusan Zigon (Mass Spectrometry Center, Jozef Stefan Institute, Ljubljana, Slovenia) for recording mass spectra. The authors thank Prof. Roger Pain for proofreading the manuscript.; Jakopin , Z , Ilas , J , Barancokova , M , Brvar , M , Tammela , P , Dolenc , M S , Tomasic , T & Kikelj , D 2017 , ' Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors ' , European Journal of Medicinal Chemistry , vol. 130 , pp. 171-184 . https://doi.org/10.1016/j.ejmech.2017.02.046; ORCID: /0000-0003-4697-8066/work/39203651; http://hdl.handle.net/10138/301097; cd5932fb-a6dd-400a-a601-6dd5575f3c7c; 85013785684; 000397180900013

الاتاحة: http://hdl.handle.net/10138/301097

المؤلفون: Larsen, Olav, Lückmann, Michael, van der Velden, Wijnand J.C., Oliva-Santiago, Marta, Brvar, Matjaz, Ulven, Trond, Frimurer, Thomas M, Karlshøj, Stefanie, Rosenkilde, Mette M

المصدر: Larsen , O , Lückmann , M , van der Velden , W J C , Oliva-Santiago , M , Brvar , M , Ulven , T , Frimurer , T M , Karlshøj , S & Rosenkilde , M M 2019 , ' Selective Allosteric Modulation of N-Terminally Cleaved, but Not Full Length CCL3 in CCR1 ' , ACS Pharmacology & Translational Science , vol. 2 , no. 6 , pp. 429-441 .

مصطلحات الفهرس: article

المؤلفون: Janežič, Matej, Pogorelčnik, Barbara, Brvar, Matjaž, Solmajer, Tom, Perdih, Andrej

المصدر: ChemistrySelect ; volume 2, issue 1, page 480-488 ; ISSN 2365-6549 2365-6549

الاتاحة: http://dx.doi.org/10.1002/slct.201601554
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fslct.201601554
https://onlinelibrary.wiley.com/doi/full/10.1002/slct.201601554

المؤلفون: Cotman, Andrej E., Trampuž, Marko, Brvar, Matjaž, Kikelj, Danijel, Ilaš, Janez, Peterlin‐Mašič, Lucija, Montalvão, Sofia, Tammela, Päivi, Frlan, Rok

المساهمون: Suomen Akatemia, Javna Agencija za Raziskovalno Dejavnost RS

المصدر: Archiv der Pharmazie ; volume 350, issue 8 ; ISSN 0365-6233 1521-4184

الاتاحة: http://dx.doi.org/10.1002/ardp.201700087
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fardp.201700087
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ardp.201700087

المؤلفون: Jakopin, Žiga, Ilaš, Janez, Barančoková, Michaela, Brvar, Matjaž, Tammela, Päivi, Sollner Dolenc, Marija, Tomašič, Tihomir, Kikelj, Danijel

المساهمون: Slovenian Research Agency, Academy of Finland, EU FP7 Project

المصدر: European Journal of Medicinal Chemistry ; volume 130, page 171-184 ; ISSN 0223-5234

الاتاحة: http://dx.doi.org/10.1016/j.ejmech.2017.02.046
https://api.elsevier.com/content/article/PII:S0223523417301198?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0223523417301198?httpAccept=text/xml

المؤلفون: Jukič, Marko, Ilaš, Janez, Brvar, Matjaž, Kikelj, Danijel, Cesar, Jožko, Anderluh, Marko

المساهمون: Slovenian Research Agency, EU FP7 Integrated Project MAREX

المصدر: European Journal of Medicinal Chemistry ; volume 125, page 500-514 ; ISSN 0223-5234

الاتاحة: http://dx.doi.org/10.1016/j.ejmech.2016.09.040
https://api.elsevier.com/content/article/PII:S022352341630770X?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S022352341630770X?httpAccept=text/xml

المؤلفون: Brown, Jane, Connolly, Stephen, Hansen, Steffen V. F., Milne, Gavin, Shimpukade, Bharat, Smyth, Don, Thomas, Gerard, Ulven, Trond, Brvar, Matjaz, Rigby, Aaron.

المصدر: Brown , J , Connolly , S , Hansen , S V F , Milne , G , Shimpukade , B , Smyth , D , Thomas , G , Ulven , T , Brvar , M & Rigby , A Sep. 27 2018 , Preparation of tetrahydroisoquinoline and tetrahydrobenzoazepine derivatives for use as GPR120 modulators. , Patent No. WO2018172727A1 .

مصطلحات الفهرس: tetrahydrobenzoazepine prepn GPR120 modulator, tetrahydroisoquinoline prepn GPR120 modulator, patent

URL: https://curis.ku.dk/portal/da/publications/preparation-of-tetrahydroisoquinoline-and-tetrahydrobenzoazepine-derivatives-for-use-as-gpr120-modulators(edf537ff-abd1-4d12-93a5-88621ab4c78e).html

المؤلفون: Zidar, Nace, Tomašič, Tihomir, Macut, Helena, Sirc, Anja, Brvar, Matjaž, Montalvão, Sofia, Tammela, Päivi, Ilaš, Janez, Kikelj, Danijel

المساهمون: Slovenian Research Agency, Academy of Finland

المصدر: European Journal of Medicinal Chemistry ; volume 117, page 197-211 ; ISSN 0223-5234

الاتاحة: http://dx.doi.org/10.1016/j.ejmech.2016.03.079
https://api.elsevier.com/content/article/PII:S022352341630263X?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S022352341630263X?httpAccept=text/xml

المؤلفون: Zidar, Nace, Macut, Helena, Tomašič, Tihomir, Brvar, Matjaž, Montalvão, Sofia, Tammela, Päivi, Solmajer, Tom, Peterlin Mašič, Lucija, Ilaš, Janez, Kikelj, Danijel

المساهمون: EU FP7 Integrated Project MAREX, Slovenian Research Agency

المصدر: Journal of Medicinal Chemistry ; volume 58, issue 15, page 6179-6194 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.5b00775
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00775

المؤلفون: Tomašič, Tihomir, Katsamakas, Sotirios, Hodnik, Žiga, Ilaš, Janez, Brvar, Matjaž, Solmajer, Tom, Montalvão, Sofia, Tammela, Päivi, Banjanac, Mihailo, Ergović, Gabrijela, Anderluh, Marko, Mašič, Lucija Peterlin, Kikelj, Danijel

المساهمون: A.G. Leventis Foundation, Seventh Framework Programme, Javna Agencija za Raziskovalno Dejavnost RS

المصدر: Journal of Medicinal Chemistry ; volume 58, issue 14, page 5501-5521 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.5b00489
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00489

المؤلفون: Pogorelčnik, Barbara, Brvar, Matjaž, Žegura, Bojana, Filipič, Metka, Solmajer, Tom, Perdih, Andrej

المصدر: ChemMedChem ; volume 10, issue 2, page 345-359 ; ISSN 1860-7179 1860-7187

الاتاحة: http://dx.doi.org/10.1002/cmdc.201402459
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcmdc.201402459
https://onlinelibrary.wiley.com/doi/full/10.1002/cmdc.201402459

المؤلفون: Pogorelčnik, Barbara, Brvar, Matjaž, Zajc, Irena, Filipič, Metka, Solmajer, Tom, Perdih, Andrej

المساهمون: Ministrstvo za Izobraževanje, Znanost in Šport

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 24, issue 24, page 5762-5768 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2014.10.042
https://api.elsevier.com/content/article/PII:S0960894X14011020?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X14011020?httpAccept=text/plain

المؤلفون: Brvar, Matjaž, Perdih, Andrej, Hodnik, Vesna, Renko, Miha, Anderluh, Gregor, Jerala, Roman, Solmajer, Tom

المصدر: Bioorganic & Medicinal Chemistry ; volume 20, issue 8, page 2572-2580 ; ISSN 0968-0896

الاتاحة: http://dx.doi.org/10.1016/j.bmc.2012.02.052
https://api.elsevier.com/content/article/PII:S096808961200154X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S096808961200154X?httpAccept=text/plain

المؤلفون: Brvar, Matjaž, Perdih, Andrej, Renko, Miha, Anderluh, Gregor, Turk, Dušan, Solmajer, Tom

المصدر: Journal of Medicinal Chemistry ; volume 55, issue 14, page 6413-6426 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/jm300395d
https://pubs.acs.org/doi/pdf/10.1021/jm300395d

المؤلفون: Brvar, Matjaž, Perdih, Andrej, Oblak, Marko, Mašič, Lucija Peterlin, Solmajer, Tom

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 20, issue 3, page 958-962 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2009.12.060
https://api.elsevier.com/content/article/PII:S0960894X09017831?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X09017831?httpAccept=text/plain