المؤلفون: Du, Steven, Fu, Dan, A Bota, Daniela, Kong, Xiao-Tang

المصدر: CNS Oncology. 13(1)

مصطلحات موضوعية: Brutons tyrosine kinase inhibitor, diffuse large B-cell lymphoma, ibrutinib, primary CNS lymphoma, relapsed or refractory primary CNS lymphoma, whole-brain radiation therapy, Humans, Piperidines, Adenine, Female, Aged, Central Nervous System Neoplasms, Pyrazoles, Pyrimidines, Neoplasm Recurrence, Local, Salvage Therapy, Remission Induction, Lymphoma

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/84t2m1jg
https://escholarship.org/content/qt84t2m1jg/qt84t2m1jg.pdf

المؤلفون: Chari, Ajai, Cornell, Robert, Gasparetto, Cristina, Karanes, Chatchada, Matous, Jeffrey, Niesvizky, Ruben, Lunning, Matthew, Usmani, Saad, Anderson, Larry, Chhabra, Saurabh, Girnius, Saulius, Shustik, Chaim, Stuart, Robert, Lee, Yihua, Salman, Zeena, Liu, Emily, Valent, Jason

المصدر: Hematological Oncology. 38(3)

مصطلحات موضوعية: Brutons tyrosine kinase inhibitor, carfilzomib, ibrutinib, multiple myeloma, Adenine, Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, Dexamethasone, Drug Resistance, Neoplasm, Female, Follow-Up Studies, Humans, Male, Middle Aged, Multiple Myeloma, Neoplasm Recurrence, Local, Oligopeptides, Piperidines, Prognosis, Pyrazoles, Pyrimidines, Salvage Therapy, Survival Rate

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/58p9v8kz

المؤلفون: Zhang, Pengyu, Solari, Fiorella A., Heemskerk, Johan W. M., Kuijpers, Marijke J. E., Sickmann, Albert, Walter, Ulrich, Jurk, Kerstin

المصدر: Zhang , P , Solari , F A , Heemskerk , J W M , Kuijpers , M J E , Sickmann , A , Walter , U & Jurk , K 2023 , ' Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets ' , International Journal of Molecular Sciences , vol. 24 , no. 9 , 7776 . https://doi.org/10.3390/ijms24097776

مصطلحات موضوعية: thrombo-inflammation, platelets, protein kinases, Bruton's tyrosine kinase, XLA, BRUTONS TYROSINE KINASE, SRC FAMILY, PHOSPHORYLATION, PHOSPHATASES, RESIDUES

Relation: https://cris.maastrichtuniversity.nl/en/publications/725d5836-4c3f-4417-9291-57d969249190

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/725d5836-4c3f-4417-9291-57d969249190
https://doi.org/10.3390/ijms24097776

المؤلفون: Neys, Stefan F. H., Verstappen, Gwenny M., Bootsma, Hendrika, Kroese, Frans G. M., Hendriks, Rudi W., Corneth, Odilia B. J.

المصدر: Neys , S F H , Verstappen , G M , Bootsma , H , Kroese , F G M , Hendriks , R W & Corneth , O B J 2022 , ' Decreased BAFF Receptor Expression and Unaltered B Cell Receptor Signaling in Circulating B Cells from Primary Sjogren's Syndrome Patients at Diagnosis ' , International Journal of Molecular Sciences , vol. 23 , no. 9 , 5101 . https://doi.org/10.3390/ijms23095101

مصطلحات موضوعية: Bruton's tyrosine kinase (BTK), B cell receptor (BCR) signaling, B-cell activating factor receptor (BAFFR, BR3), phosphoflow cytometry, primary Sjogren's syndrome (pSS), non-Sjogren sicca, BRUTONS TYROSINE KINASE, ACTIVATING FACTOR-RECEPTOR, DISEASE-ACTIVITY, SALIVARY-GLANDS, REVEALS, MEMORY, BLYS, ASSOCIATION, LYMPHOCYTES, SURVIVAL

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/1a608df0-401d-44af-bfb5-01c856c9a527
https://research.rug.nl/en/publications/1a608df0-401d-44af-bfb5-01c856c9a527
https://doi.org/10.3390/ijms23095101
https://pure.rug.nl/ws/files/220471070/ijms_23_05101_v2.pdf

المؤلفون: Duan, R.D., Goldmann, L., Brandl, R., Spannagl, M., Weber, C., Siess, W., von Hundelshausen, P.

المصدر: Duan , R D , Goldmann , L , Brandl , R , Spannagl , M , Weber , C , Siess , W & von Hundelshausen , P 2021 , ' Effects of the Btk-Inhibitors Remibrutinib (LOU064) and Rilzabrutinib (PRN1008) With Varying Btk Selectivity Over Tec on Platelet Aggregation and in vitro Bleeding Time ' , Frontiers in Cardiovascular Medicine , vol. 8 , 749022 . https://doi.org/10.3389/fcvm.2021.749022

مصطلحات موضوعية: atherothrombosis, platelet-aggregation, bleeding, PFA, MEA, BRUTONS TYROSINE KINASE, X-LINKED AGAMMAGLOBULINEMIA, THROMBUS FORMATION, CLOSURE TIME, ACTIVATION, ASPIRIN, PFA-100(TM), IBRUTINIB, ABSENCE, TRIAL

Relation: https://cris.maastrichtuniversity.nl/en/publications/9fda1fab-85f2-49c2-a935-6604d103d004

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/9fda1fab-85f2-49c2-a935-6604d103d004
https://doi.org/10.3389/fcvm.2021.749022

المؤلفون: Visser, Annie, Verstappen, Gwenny M, van der Vegt, Bert, Vissink, Arjan, Bende, Richard J, Bootsma, Hendrika, Bos, Nicolaas A, Kroese, Frans G M

المصدر: Visser , A , Verstappen , G M , van der Vegt , B , Vissink , A , Bende , R J , Bootsma , H , Bos , N A & Kroese , F G M 2020 , ' Repertoire Analysis of B-Cells Located in Striated Ducts of Salivary Glands of Patients With Sjogren's Syndrome ' , Frontiers in Immunology , vol. 11 , 1486 . https://doi.org/10.3389/fimmu.2020.01486

مصطلحات موضوعية: Sjogren's syndrome, B-cells, FcRL4, IGHV repertoire, rheumatoid factor, salivary gland, parotid gland, MALT lymphoma, BRUTONS TYROSINE KINASE, SOMATIC HYPERMUTATION, RHEUMATOID-FACTOR, DISEASE-ACTIVITY, IMMUNOGLOBULIN, RECEPTOR, LYMPHOMA, ACTIVATION, EXPRESSION, MEMORY

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/d6b5e0ab-8aa0-4006-bdff-51070de3f671
https://research.rug.nl/en/publications/d6b5e0ab-8aa0-4006-bdff-51070de3f671
https://doi.org/10.3389/fimmu.2020.01486
https://pure.rug.nl/ws/files/131454352/fimmu_11_01486.pdf

المؤلفون: Pengyu Zhang, Fiorella A. Solari, Johan W. M. Heemskerk, Marijke J. E. Kuijpers, Albert Sickmann, Ulrich Walter, Kerstin Jurk

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 7776

مصطلحات موضوعية: BRUTONS TYROSINE KINASE, protein kinases, XLA, Organic Chemistry, General Medicine, Catalysis, Computer Science Applications, Inorganic Chemistry, Bruton's tyrosine kinase, thrombo-inflammation, SRC FAMILY, platelets, Bruton’s tyrosine kinase, RESIDUES, PHOSPHATASES, Physical and Theoretical Chemistry, PHOSPHORYLATION, Molecular Biology, Spectroscopy

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cd3e5db1f4b649577e8bf6c96e739d
https://cris.maastrichtuniversity.nl/en/publications/725d5836-4c3f-4417-9291-57d969249190

المؤلفون: Busygina, Kristina, Denzinger, Viola, Bernlochner, Isabell, Weber, Christian, Lorenz, Reinhard, Siess, Wolfgang

المصدر: Busygina , K , Denzinger , V , Bernlochner , I , Weber , C , Lorenz , R & Siess , W 2019 , ' Btk Inhibitors as First Oral Atherothrombosis-Selective Antiplatelet Drugs? ' , Thrombosis and Haemostasis , vol. 119 , no. 8 , pp. 1212-1221 . https://doi.org/10.1055/s-0039-1687877

مصطلحات موضوعية: ACALABRUTINIB ACP-196, BRUTONS TYROSINE KINASE, Btk inhibitor, CA2+ ENTRY, COMPLEMENTARY ROLES, GLYCOPROTEIN-VI, GPIb, GPVI, GPVI-FC, PLATELET THROMBUS FORMATION, SRC FAMILY, TERM-FOLLOW-UP, X-LINKED AGAMMAGLOBULINEMIA, bleeding, platelet, IBRUTINIB TREATMENT

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/13352cac-75cf-4892-b996-1c7e5f2c817f
https://doi.org/10.1055/s-0039-1687877

المؤلفون: El-Sayed, Zeinab A., Abramova, Irina, Carlos Aldave, Juan, Al-Herz, Waleed, Bezrodnik, Liliana, Boukari, Rachida, Bousfiha, Ahmed Aziz, Cancrini, Caterina, Condino-Neto, Antonio, Dbaibo, Ghassan, Derfalvi, Beata, Dogu, Figen, Edgar, J. David M., Eley, Brian, El-Owaidy, Rasha Hasan, Elva Espinosa-Padilla, Sara, Galal, Nermeen, Haerynck, Filomeen, Hanna-Wakim, Rima, Hossny, Elham, Ikinciogullari, Aydan, Kamal, Ebtihal, Kanegane, Hirokazu, Kechout, Nadia, Lau, Yu Lung, Morio, Tomohiro, Moschese, Viviana, Neves, Joao Farela, Ouederni, Monia, Paganelli, Roberto, Paris, Kenneth, Pignata, Claudio, Plebani, Alessandro, Qamar, Farah Naz, Qureshi, Sonia, Radhakrishnan, Nita, Rezaei, Nima, Rosario, Nelson, Routes, John, Sanchez, Berta, Sediva, Anna, Seppänen, Mikko R. J., Serrano, Edith Gonzalez, Shcherbina, Anna, Singh, Surjit, Siniah, Sangeetha, Spadaro, Guiseppe, Tang, Mimi, Maria Vinet, Ana, Volokha, Alla, Sullivan, Kathleen E.

المساهمون: Children's Hospital, HUS Children and Adolescents, Clinicum, Department of Medicine, University Management, HUS Inflammation Center, Infektiosairauksien yksikkö

مصطلحات موضوعية: XLA, Agammaglobulinemia, Infection, Autoimmunity, Outcomes, Immunoglobulin, Therapy, PRIMARY IMMUNODEFICIENCY DISEASES, BRUTONS TYROSINE KINASE, PRIMARY HYPOGAMMAGLOBULINEMIA, INTRAVENOUS IMMUNOGLOBULIN, REPLACEMENT THERAPY, CLINICAL-FEATURES, NATIONAL-REGISTRY, BTK, EXPERIENCE, GENE, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: El-Sayed , Z A , Abramova , I , Carlos Aldave , J , Al-Herz , W , Bezrodnik , L , Boukari , R , Bousfiha , A A , Cancrini , C , Condino-Neto , A , Dbaibo , G , Derfalvi , B , Dogu , F , Edgar , J D M , Eley , B , El-Owaidy , R H , Elva Espinosa-Padilla , S , Galal , N , Haerynck , F , Hanna-Wakim , R , Hossny , E , Ikinciogullari , A , Kamal , E , Kanegane , H , Kechout , N , Lau , Y L , Morio , T , Moschese , V , Neves , J F , Ouederni , M , Paganelli , R , Paris , K , Pignata , C , Plebani , A , Qamar , F N , Qureshi , S , Radhakrishnan , N , Rezaei , N , Rosario , N , Routes , J , Sanchez , B , Sediva , A , Seppänen , M R J , Serrano , E G , Shcherbina , A , Singh , S , Siniah , S , Spadaro , G , Tang , M , Maria Vinet , A , Volokha , A & Sullivan , K E 2019 , ' X-linked agammaglobulinemia (XLA) : Phenotype, diagnosis, and therapeutic challenges around the world ' , World Allergy Organization journal , vol. 12 , no. 3 , 100018 . https://doi.org/10.1016/j.waojou.2019.100018; ORCID: /0000-0001-9733-3650/work/66034520; http://hdl.handle.net/10138/308183; 1b6c5c40-4231-4dc6-9219-75963b8682d4; 000497735900002

الاتاحة: http://hdl.handle.net/10138/308183

المؤلفون: Muftuoglu, Can, Erdem, Sevgi, Sadiqova, Aygul, Toz, Seray, Ozbel, Yusuf, Mert, Ufuk, Caner, Ayse

مصطلحات موضوعية: Ibrutinib, Leishmania infantum, BTK, Macrophage, Brutons Tyrosine Kinase, Drug Discovery, Visceral Leishmaniasis, Cells

Relation: Acta Parasitologica; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11454/76212; https://doi.org/10.1007/s11686-022-00630-5; mert, ufuk/0000-0001-8162-5325; 67; 1732; 1739

الاتاحة: https://hdl.handle.net/11454/76212
https://doi.org/10.1007/s11686-022-00630-5

المؤلفون: Lim, Ye Seul, Yoo, Sun-Mi, Patil, Vineet, Kim, Han Wool, Kim, Hyun-Hwi, Suh, Beomseon, Park, Ji Youn, Jeong, Na-rae, Park, Chi Hoon, Ryu, Je Ho, Lee, Byung-Hoon, Kim, Pilho, Lee, Song Hee

مصطلحات موضوعية: BRUTONS TYROSINE KINASE, TARGETED PROTEIN-DEGRADATION, NF-KAPPA-B, RECEPTOR, ACTIVATION, RESISTANCE, IBRUTINIB, DESIGN, INHIBITION, COMPLEX

وصف الملف: application/pdf

Relation: Hematology; http://hdl.handle.net/20.500.11750/17242; 000919671900001; 2-s2.0-85146458437; Blood Advances, v.7, no.1, pp.92 - 105

الاتاحة: https://hdl.handle.net/20.500.11750/17242
https://doi.org/10.1182/bloodadvances.2022008121

المؤلفون: Ufuk Mert, Can Müftüoğlu, Sevgi Erdem, Aygül Sadıqova, Seray Toz, Yusuf Ozbel, Ayse Caner

مصطلحات موضوعية: Visceral Leishmaniasis, Macrophage, Cells, Ibrutinib, Antiprotozoal Agents, Brutons Tyrosine Kinase, BTK, Drug Discovery, Humans, Leishmaniasis, Visceral, Parasitology, Leishmania infantum, Leishmaniasis, Leishmania donovani

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0ce4f7cb545f36c283a725c192969c
https://hdl.handle.net/11454/76212

المصدر: Frontiers in cardiovascular medicine. 8

مصطلحات موضوعية: BRUTONS TYROSINE KINASE, CLOSURE TIME, MEA, PFA, X-LINKED AGAMMAGLOBULINEMIA, PFA-100(TM), platelet-aggregation, bleeding, ABSENCE, THROMBUS FORMATION, ACTIVATION, ASPIRIN, atherothrombosis, TRIAL, IBRUTINIB

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od________83::fb332a991eac81790f500b2e5042e94b
https://cris.maastrichtuniversity.nl/en/publications/9fda1fab-85f2-49c2-a935-6604d103d004

المؤلفون: Zarrinpashneh, E, Poggioli, T, Sarathchandra, P, Lexow, J, Monassier, L, Terracciano, C, Lang, F, Damilano, F, Zhou, JQ, Rosenzweig, A, Rosenthal, N, Santini, MP

المساهمون: British Heart Foundation

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, KAPPA-B ACTIVATION, BRUTONS TYROSINE KINASE, SERUM, FAMILY, GROWTH, CANCER, METASTASIS, MECHANISMS, EXPRESSION, LETHALITY, Animals, Cell Cycle Proteins, Cell Movement, Cell Size, Disease Models, Animal, Endothelial Cells, Fibrosis, Immediate-Early Proteins, Intracellular Signaling Peptides and Proteins, Mice, Knockout, Myocardial Infarction, Myocardial Ischemia, Myocytes, Cardiac, NF-kappa B

Relation: PLoS ONE; http://hdl.handle.net/10044/1/69200; https://doi.org/10.1371/journal.pone.0080268; PG/08/111/26226

الاتاحة: http://hdl.handle.net/10044/1/69200
https://doi.org/10.1371/journal.pone.0080268

المؤلفون: Richard J Bende, Hendrika Bootsma, Gwenny M Verstappen, Nicolaas A. Bos, Bert van der Vegt, Annie Visser, Frans G. M. Kroese, Arjan Vissink

المساهمون: Personalized Healthcare Technology (PHT), Translational Immunology Groningen (TRIGR), Lifelong Learning, Education & Assessment Research Network (LEARN), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Pathology

المصدر: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, 11:1486. Frontiers Media SA
Frontiers in Immunology
Frontiers in immunology, 11:1486. Frontiers Media S.A.

مصطلحات موضوعية: 0301 basic medicine, Pathology, Clone (cell biology), Receptors, Fc, Lymphocyte Activation, IGHV repertoire, DISEASE-ACTIVITY, Salivary Glands, rheumatoid factor, ACTIVATION, 0302 clinical medicine, LYMPHOMA, Immunology and Allergy, Salivary Ducts, Gene Rearrangement, B-Lymphocyte, MALT lymphoma, Original Research, B-Lymphocytes, FcRL4, Salivary gland, Middle Aged, Parotid gland, medicine.anatomical_structure, Sjogren's syndrome, Female, Sjögren's syndrome, IGHV@, Immunoglobulin Heavy Chains, Adult, lcsh:Immunologic diseases. Allergy, EXPRESSION, medicine.medical_specialty, Immunology, B-cells, Somatic hypermutation, salivary gland, Biology, 03 medical and health sciences, RHEUMATOID-FACTOR, medicine, SOMATIC HYPERMUTATION, Humans, Aged, BRUTONS TYROSINE KINASE, RECEPTOR, MEMORY, Lymphoma, B-Cell, Marginal Zone, medicine.disease, Lymphoma, Clone Cells, 030104 developmental biology, IMMUNOGLOBULIN, lcsh:RC581-607, parotid gland, Mucosa-associated lymphoid tissue, 030215 immunology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf012f0bf48f61ee657148b3c12d530
https://research.rug.nl/en/publications/d6b5e0ab-8aa0-4006-bdff-51070de3f671

المؤلفون: Xiaowei, Wu, Mengdi, Dai, Rongrong, Cui, Yulan, Wang, Chunpu, Li, Xia, Peng, Jihui, Zhao, Bao, Wang, Yang, Dai, Dan, Feng, Tianbiao, Yang, Hualiang, Jiang, Meiyu, Geng, Jing, Ai, Mingyue, Zheng, Hong, Liu

المصدر: Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Virtual screening, SAR, structure−activity relationship, FGFR, fibroblast growth factor receptor, CADD, computer-aided drug design, EGFR, epidermal growth factor receptor, Structure−activity relationships, Antitumor efficacy, RTKs, receptor tyrosine kinases, PLCγ, phospholipase Cγ, GSH, glutathione, PK, pharmacokinetics, Original Article, Tyrosine kinase, Covalent FGFR inhibitors, MAPK, mitogen-activated protein kinase, PI3K, phosphoinositide 3-kinase, Pyrazolo[3,4-d]pyridazinone, BTK, brutons tyrosine kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::3e09b8bc56e0515d0a69dda60f23b51d
https://pubmed.ncbi.nlm.nih.gov/33777682

المؤلفون: Peirce, MJ, Brook, M, Morrice, N, Snelgrove, R, Begum, S, Lanfrancotti, A, Notley, C, Hussell, T, Cope, AP, Wait, R

المصدر: PLOS ONE , 5 (7) , Article e11465. (2010)

مصطلحات موضوعية: TUMOR-NECROSIS-FACTOR, ACTIVATED PROTEIN-KINASE, BRUTONS TYROSINE KINASE, MESSENGER-RNA STABILITY, TNF-ALPHA PRODUCTION, CANCER CELL-LINES, NF-KAPPA-B, RICH ELEMENT, POSITIVE SELECTION, MEMBRANE-PROTEINS

وصف الملف: application/pdf

Relation: https://discovery.ucl.ac.uk/id/eprint/116291/1/116291.pdf; https://discovery.ucl.ac.uk/id/eprint/116291/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/116291/1/116291.pdf
https://discovery.ucl.ac.uk/id/eprint/116291/

المؤلفون: Vargas-Vallejo, Leonardo

المساهمون: Karolinska Institutet, Clinical Research Center, Publisher, Karolinska Institutet, Kliniskt forskningscentrum, Publisher

مصطلحات موضوعية: MEDICAL AND HEALTH SCIENCES, MEDICIN OCH HÄLSOVETENSKAP, B-cells, Brutons tyrosine kinase, X-linked agammaglobulinemia, pleckstrin homology domain, cytoskeleton, nucleocytoplasmic shuttling, caveolin-1, ubiquitin, SUMO-1.

وصف الملف: electronic

URL الوصول: http://hdl.handle.net/10616/39455

المصدر: Arthritis & Rheumatology. 69(9):1850-1861

مصطلحات موضوعية: musculoskeletal diseases, BRUTONS TYROSINE KINASE, ANTIBODY-RESPONSES, DIFFERENTIATION, ICOS, PLASMA-CELLS, BONE-MARROW, ANTIGEN, DISEASE-ACTIVITY, LYMPHOCYTES, RHEUMATOID-ARTHRITIS

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___00893::b149027787292a5a321e17eabfd4544e
https://doi.org/10.1002/art.40165

المؤلفون: Tam, Constantine S., Trotman, Judith, Opat, Stephen, Burger, Jan A., Cull, Gavin, Gottlieb, David, Harrup, Rosemary, Johnston, Patrick B., Marlton, Paula, Munoz, Javier, Seymour, John F., Simpson, David, Tedeschi, Alessandra, Elstrom, Rebecca, Yu, Yiling, Tang, Zhiyu, Han, Lynn, Huang, Jane, Novotny, William, Wang, Lai, Roberts, Andrew W.

مصطلحات موضوعية: Chronic Lymphocytic-Leukemia, Brutons Tyrosine Kinase, Atrial-Fibrillation, Treated Patients, Ibrutinib, Pci-32765, Lymphoma, Collagen, Receptor, Therapy, 1303 Biochemistry, 1307 Cell Biology, 2403 Immunology, 2720 Hematology

Relation: Not set

الاتاحة: https://espace.library.uq.edu.au/view/UQ:cb37ed6