المؤلفون: Liam Hudson, Jeremy W. Mason, Matthias V. Westphal, Matthieu J. R. Richter, Jonathan R. Thielman, Bruce K. Hua, Christopher J. Gerry, Guoqin Xia, Heather L. Osswald, John M. Knapp, Zher Yin Tan, Praveen Kokkonda, Ben I. C. Tresco, Shuang Liu, Andrew G. Reidenbach, Katherine S. Lim, Jennifer Poirier, John Capece, Simone Bonazzi, Christian M. Gampe, Nichola J. Smith, James E. Bradner, Connor W. Coley, Paul A. Clemons, Bruno Melillo, C. Suk-Yee Hon, Johannes Ottl, Christoph E. Dumelin, Jonas V. Schaefer, Ann Marie E. Faust, Frédéric Berst, Stuart L. Schreiber, Frédéric J. Zécri, Karin Briner

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/36c9d05209eb47b1b03cc9fce00df87d

المؤلفون: Joshua B. Radke, Bruno Melillo, Payal Mittal, Manmohan Sharma, Amit Sharma, Yong Fu, Taher Uddin, Arthur Gonse, Eamon Comer, Stuart L. Schreiber, Anil K. Gupta, Arnab K. Chatterjee, L. David Sibley

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/54f3e31953f543ac83275cd23bb755ea

المؤلفون: Liam Hudson, Jeremy W. Mason, Matthias V. Westphal, Matthieu J. R. Richter, Jonathan R. Thielman, Bruce K. Hua, Christopher J. Gerry, Guoqin Xia, Heather L. Osswald, John M. Knapp, Zher Yin Tan, Praveen Kokkonda, Ben I. C. Tresco, Shuang Liu, Andrew G. Reidenbach, Katherine S. Lim, Jennifer Poirier, John Capece, Simone Bonazzi, Christian M. Gampe, Nichola J. Smith, James E. Bradner, Connor W. Coley, Paul A. Clemons, Bruno Melillo, C. Suk-Yee Hon, Johannes Ottl, Christoph E. Dumelin, Jonas V. Schaefer, Ann Marie E. Faust, Frédéric Berst, Stuart L. Schreiber, Frédéric J. Zécri, Karin Briner

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/d2f9e92baa034e31a3064fe3179e5c22

المؤلفون: Claudia A. Jette, Christopher O. Barnes, Sharon M. Kirk, Bruno Melillo, Amos B. Smith, Pamela J. Bjorkman

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/5d705e751653456d99a85bb8fb085d65

المؤلفون: Manmohan Sharma, Nipun Malhotra, Manickam Yogavel, Karl Harlos, Bruno Melillo, Eamon Comer, Arthur Gonse, Suhel Parvez, Branko Mitasev, Francis G. Fang, Stuart L. Schreiber, Amit Sharma

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/96b3e407ffe647c5b54ac432fe843d79

المؤلفون: Navid Madani, Amy M. Princiotto, Linh Mach, Shilei Ding, Jérémie Prevost, Jonathan Richard, Bhavna Hora, Laura Sutherland, Connie A. Zhao, Brandon P. Conn, Todd Bradley, M. Anthony Moody, Bruno Melillo, Andrés Finzi, Barton F. Haynes, Amos B. Smith III, Sampa Santra, Joseph Sodroski

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/ac213354426e4f05910a41474b6a0b00

المؤلفون: Todd Bradley, Ashley Trama, Nancy Tumba, Elin Gray, Xiaozhi Lu, Navid Madani, Fatemeh Jahanbakhsh, Amanda Eaton, Shi-Mao Xia, Robert Parks, Krissey E. Lloyd, Laura L. Sutherland, Richard M. Scearce, Cindy M. Bowman, Susan Barnett, Salim S. Abdool-Karim, Scott D. Boyd, Bruno Melillo, Amos B. Smith III, Joseph Sodroski, Thomas B. Kepler, S.Munir Alam, Feng Gao, Mattia Bonsignori, Hua-Xin Liao, M. Anthony Moody, David Montefiori, Sampa Santra, Lynn Morris, Barton F. Haynes

المصدر: EBioMedicine, Vol 12, Iss C, Pp 196-207 (2016)

مصطلحات موضوعية: Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396416304029; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/70ba80d336514e81baec839d541fe0d3

المؤلفون: Jonathan Richard, Beatriz Pacheco, Neelakshi Gohain, Maxime Veillette, Shilei Ding, Nirmin Alsahafi, William D. Tolbert, Jérémie Prévost, Jean-Philippe Chapleau, Mathieu Coutu, Manxue Jia, Nathalie Brassard, Jongwoo Park, Joel R. Courter, Bruno Melillo, Loïc Martin, Cécile Tremblay, Beatrice H. Hahn, Daniel E. Kaufmann, Xueling Wu, Amos B. Smith III, Joseph Sodroski, Marzena Pazgier, Andrés Finzi

المصدر: EBioMedicine, Vol 12, Iss C, Pp 208-218 (2016)

مصطلحات موضوعية: HIV-1, Envelope glycoproteins, CD4, Non-neutralizing antibodies, ADCC, CD4-mimetics, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396416304121; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/ee6c30dcd51740f589ceca78a336e2ea

المؤلفون: Guillaume Beaudoin-Bussières, Jérémie Prévost, Gabrielle Gendron-Lepage, Bruno Melillo, Junhua Chen, Amos B. Smith III, Marzena Pazgier, Andrés Finzi

المصدر: Microorganisms, Vol 8, Iss 5, p 710 (2020)

مصطلحات موضوعية: HIV-1, ADCC, cluster A, coreceptor binding site, guinea pigs, small CD4 mimetics, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2076-2607/8/5/710; https://doaj.org/toc/2076-2607

URL الوصول: https://doaj.org/article/0c75b452eb3e4759b4ce066bfa207b29

المؤلفون: Jonathan Richard, Maxime Veillette, Shilei Ding, Daria Zoubchenok, Nirmin Alsahafi, Mathieu Coutu, Nathalie Brassard, Jongwoo Park, Joel R. Courter, Bruno Melillo, Amos B. Smith III, George M. Shaw, Beatrice H. Hahn, Joseph Sodroski, Daniel E. Kaufmann, Andrés Finzi

المصدر: EBioMedicine, Vol 3, Iss C, Pp 122-134 (2016)

مصطلحات موضوعية: HIV-1, Envelope glycoproteins, gp120, CD4, CD4-bound conformation, Non-neutralizing antibodies, ADCC, CD4-mimetics, Bystander killing, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396415302383; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/cfaf156d6da54776b9c398895534db11

المؤلفون: Alon Herschhorn, Xiaochu Ma, Christopher Gu, John D. Ventura, Luis Castillo-Menendez, Bruno Melillo, Daniel S. Terry, Amos B. Smith, Scott C. Blanchard, James B. Munro, Walther Mothes, Andrés Finzi, Joseph Sodroski

المصدر: mBio, Vol 7, Iss 5 (2016)

مصطلحات موضوعية: Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/554073aa2fb04b81baef67f9a2afc910

المؤلفون: Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D. Rosarda, Thu Nguyen, Chloris Li-Ma, Evert Njomen, Bruno Melillo, Sergei Kutseikin, Enrique Saez, Benjamin F. Cravatt, John R. Teijaro, R. Luke Wiseman, Michael J. Bollong

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Pharmacology, Immunology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, develop pharmacologic approaches, numerous covalent molecules, profile inflammasome inhibition, numerous inflammatory disorders, compound allows covalent, important inflammatory complex, inhibit inflammasome assembly, inflammatory complex, inflammasome assembly, covalent targeting, inflammatory cytokines, compound vlx1570, nlrp3 inflammasome, recent identification, intermolecular cross, electrophilic compounds, continued development, common mechanism, aberrant overactivation

Relation: https://figshare.com/articles/journal_contribution/Covalent_Targeting_As_a_Common_Mechanism_for_Inhibiting_NLRP3_Inflammasome_Assembly/24977306

الاتاحة: https://doi.org/10.1021/acschembio.3c00330.s001
https://figshare.com/articles/journal_contribution/Covalent_Targeting_As_a_Common_Mechanism_for_Inhibiting_NLRP3_Inflammasome_Assembly/24977306

المؤلفون: Kevin A. Scott, Nathalie Ropek, Bruno Melillo, Stuart L. Schreiber, Benjamin F. Cravatt, Ekaterina V. Vinogradova

المصدر: Current Research in Chemical Biology, Vol 2, Iss , Pp 100028- (2022)

مصطلحات موضوعية: Biochemistry, QD415-436

Relation: http://www.sciencedirect.com/science/article/pii/S2666246922000106; https://doaj.org/toc/2666-2469; https://doaj.org/article/008f49b19aa54f3a96b80cb71a2a6cb0

الاتاحة: https://doi.org/10.1016/j.crchbi.2022.100028
https://doaj.org/article/008f49b19aa54f3a96b80cb71a2a6cb0

المؤلفون: Branko Mitasev (2260015), Jiong Yang (82529), Fabian Gusovsky (6755774), Dixit Girish (11436246), Anil Shahaji Khile (11436249), Venkata Sasidhar Balla (11436252), Venugopalarao Vikram (11436255), Anand Vaddi (11436258), Srikanth Bathula (11436261), Srinivasa Rao Sugandham (11436264), Chiranjeevi Terli (11436267), Vijay Kalla (11436270), Pavan Kumar Rayaprolu (11436273), Ravi Kumar Talabhakthula (11436276), Masaharu Gotoda (11436279), Bruno Melillo (1378404), Stuart L. Schreiber (189260), Francis G. Fang (4540849)

مصطلحات موضوعية: Biochemistry, Genetics, Evolutionary Biology, Developmental Biology, Marine Biology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, substantially reduced cost, proper ancillary functionality, planned reductive amination, early quantitative installation, diastereomeric salt resolution, conveniently differentiated vicinal, based synthetic route, tandem aziridine ring, membered diazocene ring, >- diol suitable, trisubstituted azetidine scaffold, antimalarial agent brd5018, antimalarial brd5018, azetidine ring, diol template, wittig sequence, wittig reaction, waste generation, synthesis resulting, syn <, stage reaction, sonogashira coupling, quality control

Relation: https://figshare.com/articles/journal_contribution/Crystallization-Based_Synthetic_Route_to_Antimalarial_Agent_BRD5018_Diazocene_Ring_Formation_via_a_Staudinger-aza-Wittig_Reaction_on_an_Azetidine-Ribose_Template/16622490

الاتاحة: https://doi.org/10.1021/acs.oprd.1c00225.s001

المؤلفون: Hannah C. Feldman, Elisa Merlini, Carlos Guijas, Kristen E. DeMeester, Evert Njomen, Ellen M. Kozina, Minoru Yokoyama, Ekaterina Vinogradova, Holly T. Reardon, Bruno Melillo, Stuart L. Schreiber, Andrea Loreto, Jacqueline L. Blankman, Benjamin F. Cravatt

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(35)

مصطلحات موضوعية: Armadillo Domain Proteins, Proteomics, Cytoskeletal Proteins, Multidisciplinary, NAD+ Nucleosidase, Homeostasis, Cysteine, Axons

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2677a7e30b0fa14c560e8dc1e85639b4
https://pubmed.ncbi.nlm.nih.gov/35994671

المؤلفون: Michael R. Lazear, Jarrett R. Remsberg, Martin G. Jaeger, Katherine Rothamel, Hsuan-lin Her, Kristen E. DeMeester, Evert Njomen, Simon J. Hogg, Jahan Rahman, Landon R. Whitby, Sang Joon Won, Michael A. Schafroth, Daisuke Ogasawara, Minoru Yokoyama, Garrett L. Lindsey, Haoxin Li, Jason Germain, Sabrina Barbas, Joan Vaughan, Thomas W. Hanigan, Vincent F. Vartabedian, Christopher J. Reinhardt, Melissa M. Dix, Seong Joo Koo, Inha Heo, John R. Teijaro, Gabriel M. Simon, Brahma Ghosh, Omar Abdel-Wahab, Kay Ahn, Alan Saghatelian, Bruno Melillo, Stuart L. Schreiber, Gene W. Yeo, Benjamin F. Cravatt

مصطلحات موضوعية: Cell Biology, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07f22999c7fd8b3058ebc700cdfeab3
https://doi.org/10.1101/2022.12.12.520090

المؤلفون: Francis G. Fang, Fabian Gusovsky, Vijay Kalla, Venkata Sasidhar Balla, Dixit Girish, Chiranjeevi Terli, Branko Mitasev, Ravi Kumar Talabhakthula, Venugopalarao Vikram, Srinivasa Rao Sugandham, Bruno Melillo, Anand Vaddi, Jiong Yang, Stuart L. Schreiber, Srikanth Bathula, Pavan Kumar Rayaprolu, Anil Shahaji Khile, Masaharu Gotoda

المصدر: Organic Process Research & Development. 26:817-831

مصطلحات موضوعية: chemistry.chemical_compound, law, Chemistry, Stereochemistry, Organic Chemistry, Wittig reaction, Azetidine, Ribose, Antimalarial Agent, Physical and Theoretical Chemistry, Crystallization, Ring (chemistry), law.invention

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::555e4ce3e36547f4ee636a2b8a25c676
https://doi.org/10.1021/acs.oprd.1c00225

المؤلفون: Liam Hudson, Jeremy W. Mason, Matthias V. Westphal, Matthieu J. R. Richter, Jonathan R. Thielman, Bruce K. Hua, Christopher J. Gerry, Guoqin Xia, Heather L. Osswald, John M. Knapp, Zher Yin Tan, Praveen Kokkonda, Ben I. C. Tresco, Shuang Liu, Andrew G. Reidenbach, Katherine S. Lim, Jennifer Poirier, John Capece, Simone Bonazzi, Christian M. Gampe, Nichola J. Smith, James E. Bradner, Connor W. Coley, Paul A. Clemons, Bruno Melillo, C. Suk-Yee Hon, Johannes Ottl, Christoph E. Dumelin, Jonas V. Schaefer, Ann Marie E. Faust, Frédéric Berst, Stuart L. Schreiber, Frédéric J. Zécri, Karin Briner

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ea89009e90b9f024b527255fb7155d39
https://doi.org/10.1101/2022.10.16.512431

المؤلفون: Yongfeng Tao, David Remillard, Ekaterina V. Vinogradova, Minoru Yokoyama, Sofia Banchenko, David Schwefel, Bruno Melillo, Stuart L. Schreiber, Xiaoyu Zhang, Benjamin F. Cravatt

المصدر: Journal of the American Chemical Society. 144(40)

مصطلحات موضوعية: Proteomics, Acrylamide, Chimera, Ubiquitin-Protein Ligases, General Chemistry, Ligands, Biochemistry, Catalysis, Colloid and Surface Chemistry, Proteolysis, Azetidines, Humans, Intercellular Signaling Peptides and Proteins, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96aee16143c172b53e7aabc1498ccc9f
https://pubmed.ncbi.nlm.nih.gov/36170674

المؤلفون: Alex Reed, Taka-Aki Ichu, Natalia Milosevich, Bruno Melillo, Michael A. Schafroth, Yuka Otsuka, Louis Scampavia, Timothy P. Spicer, Benjamin F. Cravatt

المصدر: ACS chemical biology. 17(6)

مصطلحات موضوعية: Mice, Intestinal Absorption, Liver, Molecular Medicine, 1-Acylglycerophosphocholine O-Acyltransferase, Animals, Ferroptosis, Humans, General Medicine, Biochemistry, Phospholipids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60907f7c14595d43ee81b6c6fbe50da
https://pubmed.ncbi.nlm.nih.gov/35658397