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1Academic Journal
المؤلفون: Wigger, Leonore, Barovic, Marko, Brunner, Andreas-David, Marzetta, Flavia, Schöniger, Eyke, Mehl, Florence, Kipke, Nicole, Friedland, Daniela, Burdet, Frederic, Kessler, Camille, Lesche, Mathias, Thorens, Bernard, Bonifacio, Ezio, Legido-Quigley, Cristina, Barbier Saint Hilaire, Pierre, Delerive, Philippe, Dahl, Andreas, Klose, Christian, Gerl, Mathias J., Simons, Kai, Aust, Daniela, Weitz, Jürgen, Distler, Marius, Schulte, Anke M., Mann, Matthias, Ibberson, Mark, Solimena, Michele
مصطلحات موضوعية: lipids, type 2 diabetes (T2D), pancreatic islets, multi-omics analysis, Lipide, Typ-2-Diabetes (T2D), Pankreasinseln, Multi-omics-Analyse, info:eu-repo/classification/ddc/610, ddc:610
Relation: info:eu-repo/grantAgreement/European Commission/H2020 - IMI2-RIA/115881//Assessing risk and progression of prediabetes and type 2 diabetes to enable disease modification/RHAPSODY
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2Academic Journal
المؤلفون: Jones, Amanda K., Bajrami, Besnik, Campbell, Morgan K., Erzurumluoglu, Abdullah Mesut, Guo, Qiusha, Chen, Hongxing, Zhang, Xiaomei, Zeveleva, Svetlana, Kvaskoff, David, Brunner, Andreas-David, Muller, Stefanie, Gathey, Vasudha, Dave, Rajvee M., Tanner, James W., Rixen, Sophia, Struwe, Michel A., Phoenix, Kathryn, Klumph, Kaitlyn J., Robinson, Heather, Veyel, Daniel, Muller, Annkatrin, Noyvert, Boris, Bartholdy, Boris Alexander, Steixner-Kumar, Agnes A., Stutzki, Jan, Drichel, Dmitriy, Omland, Steffen, Sheehan, Ryan, Hill, Jon, Bretschneider, Tom, Gottschling, Dirk, Scheidig, Axel J., Clement, Bernd, Giera, Martin, Ding, Zhihao, Broadwater, John, Warren, Curtis R.
المصدر: Hepatology Communications ; volume 8, issue 5 ; ISSN 2471-254X
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3Academic Journal
المؤلفون: Neukam, Martin, Sala, Pia, Brunner, Andreas-David, Ganß, Katharina, Palladini, Alessandra, Grzybek, Michal, Topcheva, Oleksandra, Vasiljević, Jovana, Broichhagen, Johannes, Johnsson, Kai, Kurth, Thomas, Mann, Matthias, Coskun, Ünal, Solimena, Michele
المساهمون: EFPIA, German Israeli Foundation for Scientific Research and Development, Swiss State Secretariat for Education Research and Innovation
المصدر: Cell Reports ; volume 43, issue 3, page 113836 ; ISSN 2211-1247
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4Academic Journal
المؤلفون: Chen, Jin, Brunner, Andreas-David, Cogan, J Zachery, Nuñez, James K, Fields, Alexander P, Adamson, Britt, Itzhak, Daniel N, Li, Jason Y, Mann, Matthias, Leonetti, Manuel D, Weissman, Jonathan S
المصدر: Science. 367(6482)
مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, 1.1 Normal biological development and functioning, Generic health relevance, CRISPR-Cas Systems, Humans, Open Reading Frames, Operon, Peptides, Protein Biosynthesis, RNA, Messenger, Ribosomes, Transcriptome, General Science & Technology
وصف الملف: application/pdf
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5Academic Journal
المؤلفون: Mund, Andreas, Coscia, Fabian, Kriston, Andras, Hollandi, Reka, Kovacs, Ferenc, Brunner, Andreas-David, Migh, Ede, Schweizer, Lisa, Santos, Alberto, Bzorek, Michael, Naimy, Soraya, Rahbek-Gjerdrum, Lise Mette, Dyring-Andersen, Beatrice, Bulkescher, Jutta, Lukas, Claudia, Eckert, Mark Adam, Lengyel, Ernst, Gnann, Christian, Lundberg, Emma, Horvath, Peter, Mann, Matthias
المساهمون: Institute for Molecular Medicine Finland
مصطلحات موضوعية: Extraction, Melanoma, Mutations, Nucleus segmentation, Package, Peptide identification, Biomedicine
وصف الملف: application/pdf
Relation: The authors thank M. Ryk ae r, J. Madsen (NNF CPR Mass Spectrometry Platform, University of Copenhagen) and L. Drici (NNF CPR Proteomics Program) as well as J. Mueller (MPIB Munich) for technical assistance. We acknowledge F. Hoffmann, C. Greb and F. Schlaudraff from Leica for technical support; T. Danka and M. Kovacs for fruitful scientific discussions; and T. Hartig Braunstein, P. Hernandez-Varas and C. Prats from the Core Facility of Integrated Microscopy for microscopy support. We thank J. Lukas for scientific support and guidance and J. Percival for the scientific illustrations (Illustration Ltd.). This work was supported by grants from the Novo Nordisk Foundation (grant agreements NNF14CC0001 and NNF15CC0001) and the Max Planck Society for the Advancement of Science and by the Chan Zuckerberg Initiative for partial funding of the cell cycle work (grant CZF2019-002448) to E. Lundberg, M.M. and P.H. F.C. acknowledges the European Union's Horizon 2020 Research and Innovation Programme under grant agreement 846795 (Marie Skodowska-Curie grant) and the German Ministry of Education and Research (BMBF), as part of the National Research Node 'Mass Spectrometry in Systems Medicine' (MSCoreSys), under grant agreement 161L0222. B.D.A. acknowledges support from the Lundbeck Foundation (R252-2017-1414) and the Novo Nordisk Foundation (NNF20OC0065720). P.H., R.H., F.K., E.M. and A.K. acknowledge support from the LENDULET-BIOMAG Grant (2018-342), European Regional Development Funds (GINOP-2.2.1-15-2017-00072), H2020 (ERAPERMED-COMPASS, ERAPERMED-SYMMETRY, DiscovAIR, FAIR-CHARM), OTKA-SNN, TKP2021-EGA09 and ELKH-Excellence grants. E. Lengyel is supported by NIH R35CA264619 and the Chan Zuckerberg Initiative (CZIF2019-002435). We acknowledge S. Ito and H. Masai (Tokyo Metropolitan Institute of Medical Science) for providing the stable U2OS FUCCI cell line. The LCK-GFP plasmid was a gift from S. Green (Addgene, plasmid 61099).; Mund , A , Coscia , F , Kriston , A , Hollandi , R , Kovacs , F , Brunner , A-D , Migh , E , Schweizer , L , Santos , A , Bzorek , M , Naimy , S , Rahbek-Gjerdrum , L M , Dyring-Andersen , B , Bulkescher , J , Lukas , C , Eckert , M A , Lengyel , E , Gnann , C , Lundberg , E , Horvath , P & Mann , M 2022 , ' Deep Visual Proteomics defines single-cell identity and heterogeneity ' , Nature Biotechnology , vol. 40 , no. 8 , pp. 1231–1240 . https://doi.org/10.1038/s41587-022-01302-5; http://hdl.handle.net/10138/354951; e4d67b5c-8197-480f-9696-3ab7ecb6c143; 85130484429; 000798052500002
الاتاحة: http://hdl.handle.net/10138/354951
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6Academic Journal
المؤلفون: Thielert, Marvin, Itang, Ericka C.M., Ammar, Constantin, Rosenberger, Florian A., Bludau, Isabell, Schweizer, Lisa, Nordmann, Thierry M., Skowronek, Patricia, Wahle, Maria, Zeng, Wen Feng, Zhou, Xie Xuan, Brunner, Andreas David, Richter, Sabrina, Levesque, Mitchell P., Theis, Fabian J., Steger, Martin, Mann, Matthias
المصدر: Thielert , M , Itang , E C M , Ammar , C , Rosenberger , F A , Bludau , I , Schweizer , L , Nordmann , T M , Skowronek , P , Wahle , M , Zeng , W F , Zhou , X X , Brunner , A D , Richter , S , Levesque , M P , Theis , F J , Steger , M & Mann , M 2023 , ' Robust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel ' , Molecular Systems Biology , vol. 19 , ....
مصطلحات موضوعية: DIA, dimethyl labeling, multiplexing, single cells, spatial proteomics
وصف الملف: application/pdf
الاتاحة: https://researchprofiles.ku.dk/da/publications/robust-dimethylbased-multiplexdia-doubles-singlecell-proteome-depth-via-a-reference-channel(5fe3a36c-ffb6-4c07-a789-6a1022d2917d).html
https://doi.org/10.15252/msb.202211503
https://curis.ku.dk/ws/files/380155826/thielert_et_al_2023_robust_dimethyl_based_multiplex_dia_doubles_single_cell_proteome_depth_via_a_reference_channel.pdf -
7Academic Journal
المؤلفون: Michaelis, André C, Brunner, Andreas-David, Zwiebel, Maximilian, Meier, Florian, Strauss, Maximilian T, Bludau, Isabell, Mann, Matthias
المصدر: Michaelis , A C , Brunner , A-D , Zwiebel , M , Meier , F , Strauss , M T , Bludau , I & Mann , M 2023 , ' The social and structural architecture of the yeast protein interactome ' , Nature , vol. 624 , no. 7990 , pp. 192-200 . https://doi.org/10.1038/s41586-023-06739-5
مصطلحات موضوعية: Mass Spectrometry, Protein Interaction Mapping/methods, Proteome/chemistry, Reproducibility of Results, Saccharomyces cerevisiae/chemistry, Protein Interaction Maps, Saccharomyces cerevisiae Proteins/chemistry, Epigenesis, Genetic, Databases, Factual
وصف الملف: application/pdf
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8Academic Journal
المؤلفون: Skowronek, Patricia, Thielert, Marvin, Voytik, Eugenia, Tanzer, Maria C, Hansen, Fynn M, Willems, Sander, Karayel, Ozge, Brunner, Andreas-David, Meier, Florian, Mann, Matthias
المصدر: Skowronek , P , Thielert , M , Voytik , E , Tanzer , M C , Hansen , F M , Willems , S , Karayel , O , Brunner , A-D , Meier , F & Mann , M 2022 , ' Rapid and In-Depth Coverage of the (Phospho-)Proteome With Deep Libraries and Optimal Window Design for dia-PASEF ' , Molecular and Cellular Proteomics , vol. 21 , no. 9 , 100279 . https://doi.org/10.1016/j.mcpro.2022.100279
مصطلحات موضوعية: Animals, Chromatography, Liquid/methods, Epidermal Growth Factor, Humans, Mammals/metabolism, Proteome/metabolism, Proteomics/methods, Tandem Mass Spectrometry/methods
وصف الملف: application/pdf
الاتاحة: https://researchprofiles.ku.dk/da/publications/rapid-and-indepth-coverage-of-the-phosphoproteome-with-deep-libraries-and-optimal-window-design-for-diapasef(a22049b2-a4ed-47d2-b7b2-ad7dad512b71).html
https://doi.org/10.1016/j.mcpro.2022.100279
https://curis.ku.dk/ws/files/321962504/1_s2.0_S1535947622000871_main.pdf -
9Academic Journal
المؤلفون: Mund, Andreas, Coscia, Fabian, Kriston, András, Hollandi, Réka, Kovács, Ferenc, Brunner, Andreas-David, Migh, Ede, Schweizer, Lisa, Santos, Alberto, Bzorek, Michael, Naimy, Soraya, Rahbek-Gjerdrum, Lise Mette, Dyring-Andersen, Beatrice, Bulkescher, Jutta, Lukas, Claudia, Eckert, Mark Adam, Lengyel, Ernst, Gnann, Christian, Lundberg, Emma, Horvath, Peter, Mann, Matthias
المصدر: Mund , A , Coscia , F , Kriston , A , Hollandi , R , Kovács , F , Brunner , A-D , Migh , E , Schweizer , L , Santos , A , Bzorek , M , Naimy , S , Rahbek-Gjerdrum , L M , Dyring-Andersen , B , Bulkescher , J , Lukas , C , Eckert , M A , Lengyel , E , Gnann , C , Lundberg , E , Horvath , P & Mann , M 2022 , ' Deep Visual Proteomics defines single-cell identity and heterogeneity ' , Nature ....
وصف الملف: application/pdf
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10Academic Journal
المؤلفون: Brunner, Andreas-David, Thielert, Marvin, Vasilopoulou, Catherine, Ammar, Constantin, Coscia, Fabian, Mund, Andreas, Hoerning, Ole B, Bache, Nicolai, Apalategui, Amalia, Lubeck, Markus, Richter, Sabrina, Fischer, David S, Raether, Oliver, Park, Melvin A, Meier, Florian, Theis, Fabian J, Mann, Matthias
المصدر: Brunner , A-D , Thielert , M , Vasilopoulou , C , Ammar , C , Coscia , F , Mund , A , Hoerning , O B , Bache , N , Apalategui , A , Lubeck , M , Richter , S , Fischer , D S , Raether , O , Park , M A , Meier , F , Theis , F J & Mann , M 2022 , ' Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation ' , Molecular Systems Biology , vol. 18 , no. 3 , e10798 . https://doi.org/10.15252/msb.202110798
وصف الملف: application/pdf
الاتاحة: https://researchprofiles.ku.dk/da/publications/ultrahigh-sensitivity-mass-spectrometry-quantifies-singlecell-proteome-changes-upon-perturbation(8df9085f-3dce-47d6-9ac7-d2f8f489d459).html
https://doi.org/10.15252/msb.202110798
https://curis.ku.dk/ws/files/303803791/Molecular_Systems_Biology_2022_Brunner_Ultra_u2010high_sensitivity_mass_spectrometry_quantifies_single_u2010cell_proteome.pdf -
11Academic Journal
المؤلفون: Cho, Nathan H., Cheveralls, Keith C., Brunner, Andreas David, Kim, Kibeom, Michaelis, André C., Raghavan, Preethi, Kobayashi, Hirofumi, Savy, Laura, Li, Jason Y., Canaj, Hera, Kim, James Y.S., Stewart, Edna M., Gnann, Christian, McCarthy, Frank, Cabrera, Joana P., Brunetti, Rachel M., Chhun, Bryant B., Dingle, Greg, Hein, Marco Y., Huang, Bo, Mehta, Shalin B., Weissman, Jonathan S., Gómez-Sjöberg, Rafael, Itzhak, Daniel N., Royer, Loïc A., Mann, Matthias, Leonetti, Manuel D.
المصدر: Cho , N H , Cheveralls , K C , Brunner , A D , Kim , K , Michaelis , A C , Raghavan , P , Kobayashi , H , Savy , L , Li , J Y , Canaj , H , Kim , J Y S , Stewart , E M , Gnann , C , McCarthy , F , Cabrera , J P , Brunetti , R M , Chhun , B B , Dingle , G , Hein , M Y , Huang , B , Mehta , S B , Weissman , ....
وصف الملف: application/pdf
الاتاحة: https://researchprofiles.ku.dk/da/publications/opencell(54ba0e5b-3940-45f1-83ff-c8e223705e5a).html
https://doi.org/10.1126/science.abi6983
https://curis.ku.dk/ws/files/358458245/nihms_1799003.pdf -
12Academic Journal
المؤلفون: Voytik, Eugenia, Bludau, Isabell, Willems, Sander, Hansen, Fynn M., Brunner, Andreas-David, Strauss, Maximilian T., Mann, Matthias
المصدر: Voytik , E , Bludau , I , Willems , S , Hansen , F M , Brunner , A-D , Strauss , M T & Mann , M 2022 , ' AlphaMap : an open-source Python package for the visual annotation of proteomics data with sequence-specific knowledge ' , Bioinformatics , vol. 38 , no. 3 , pp. 849-852 . https://doi.org/10.1093/bioinformatics/btab674
وصف الملف: application/pdf
الاتاحة: https://researchprofiles.ku.dk/da/publications/alphamap(d93e75ad-c786-4b56-8f4b-6e1d03af0ce8).html
https://doi.org/10.1093/bioinformatics/btab674
https://curis.ku.dk/ws/files/291300923/btab674.pdf -
13Academic Journal
المؤلفون: Mund, Andreas, Brunner, Andreas-David, Mann, Matthias
المساهمون: Novo Nordisk Fonden, Chan Zuckerberg Initiative, Max-Planck-Gesellschaft
المصدر: Molecular Cell ; volume 82, issue 12, page 2335-2349 ; ISSN 1097-2765
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14Academic Journal
المؤلفون: Bhatia, Harsharan Singh, Brunner, Andreas-David, Öztürk, Furkan, Kapoor, Saketh, Rong, Zhouyi, Mai, Hongcheng, Thielert, Marvin, Ali, Mayar, Al-Maskari, Rami, Paetzold, Johannes Christian, Kofler, Florian, Todorov, Mihail Ivilinov, Molbay, Muge, Kolabas, Zeynep Ilgin, Negwer, Moritz, Hoeher, Luciano, Steinke, Hanno, Dima, Alina, Gupta, Basavdatta, Kaltenecker, Doris, Caliskan, Özüm Sehnaz, Brandt, Daniel, Krahmer, Natalie, Müller, Stephan, Lichtenthaler, Stefan Frieder, Hellal, Farida, Bechmann, Ingo, Menze, Bjoern, Theis, Fabian, Mann, Matthias, Ertürk, Ali
المصدر: Cell ; volume 185, issue 26, page 5040-5058.e19 ; ISSN 0092-8674
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15Academic Journal
المؤلفون: Dietmann, Anelia, Wenz, Elena, van der Meer, Julia, Ringli, Maya, Warncke, Jan D, Edwards, Ellen, Schmidt, Markus H, Bernasconi, Corrado A, Nirkko, Arto, Strub, Mathias, Miano, Silvia, Manconi, Mauro, Acker, Jens, von Manitius, Sigrid, Baumann, Christian R, Valko, Philip O, Yilmaz, Bahtiyar, Brunner, Andreas-David, Tzovara, Athina, Zhang, Zhongxing, Largiadèr, Carlo R, Tafti, Mehdi, Latorre, Daniela, Sallusto, Federica, Khatami, Ramin, Bassetti, Claudio L A
المصدر: Dietmann, Anelia; Wenz, Elena; van der Meer, Julia; Ringli, Maya; Warncke, Jan D; Edwards, Ellen; Schmidt, Markus H; Bernasconi, Corrado A; Nirkko, Arto; Strub, Mathias; Miano, Silvia; Manconi, Mauro; Acker, Jens; von Manitius, Sigrid; Baumann, Christian R; Valko, Philip O; Yilmaz, Bahtiyar; Brunner, Andreas-David; Tzovara, Athina; Zhang, Zhongxing; Largiadèr, Carlo R; Tafti, Mehdi; Latorre, Daniela; Sallusto, Federica; Khatami, Ramin; Bassetti, Claudio L A (2021). The Swiss Primary Hypersomnolence and Narcolepsy Cohort study (SPHYNCS): Study protocol for a prospective, multicentre cohort observational study. Journal of Sleep Research, 30(5):e13296.
مصطلحات موضوعية: Clinic for Neurology, 610 Medicine & health
وصف الملف: application/pdf
Relation: https://www.zora.uzh.ch/id/eprint/209446/1/jsr.13296.pdf; info:pmid/33813771; urn:issn:0962-1105
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16Academic Journal
المؤلفون: Meier, Florian, Köhler, Niklas D., Brunner, Andreas-David, Wanka, Jean-Marc H., Voytik, Eugenia, Strauss, Maximilian T., Theis, Fabian J., Mann, Matthias
مصطلحات موضوعية: article, ScholarlyArticle, ddc:500, Machine learning, Mass spectrometry, Proteomics
وصف الملف: 12 Seiten
Relation: Nature Communications -- 2041-1723 -- http://uri.gbv.de/document/gvk:ppn:626457688 -- 2553671-0 -- http://www.nature.com/ncomms/ -- http://www.bibliothek.uni-regensburg.de/ezeit/?2553671 -- http://d-nb.info/1002399459
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17Academic Journal
المؤلفون: Vasilopoulou, Catherine G., Sulek, Karolina, Brunner, Andreas-David, Meitei, Ningombam Sanjib, Schweiger-Hufnagel, Ulrike, Meyer, Sven W., Barsch, Aiko, Mann, Matthias, Meier, Florian
المصدر: Nature Communications ; volume 12, issue 1 ; ISSN 2041-1723
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18Academic Journal
المؤلفون: Meier, Florian, Brunner, Andreas-David, Frank, Max, Ha, Annie, Bludau, Isabell, Voytik, Eugenia, Kaspar-Schoenefeld, Stephanie, Lubeck, Markus, Raether, Oliver, Bache, Nicolai, Aebersold, Ruedi, Collins, Ben C., Röst, Hannes L., Mann, Matthias
المصدر: Meier , F , Brunner , A-D , Frank , M , Ha , A , Bludau , I , Voytik , E , Kaspar-Schoenefeld , S , Lubeck , M , Raether , O , Bache , N , Aebersold , R , Collins , B C , Röst , H L & Mann , M 2020 , ' diaPASEF: parallel accumulation–serial fragmentation combined with data-independent acquisition ' , Nature Methods , vol. 17 , pp. 1229-1236 . https://doi.org/10.1038/s41592-020-00998-0
وصف الملف: application/pdf
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19Academic Journal
المؤلفون: Vasilopoulou, Catherine G, Sulek, Karolina, Brunner, Andreas-David, Meitei, Ningombam Sanjib, Schweiger-Hufnagel, Ulrike, Meyer, Sven W, Barsch, Aiko, Mann, Matthias, Meier, Florian
المصدر: Vasilopoulou , C G , Sulek , K , Brunner , A-D , Meitei , N S , Schweiger-Hufnagel , U , Meyer , S W , Barsch , A , Mann , M & Meier , F 2020 , ' Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts ' , Nature Communications , vol. 11 , no. 1 , 331 . https://doi.org/10.1038/s41467-019-14044-x
وصف الملف: application/pdf
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20Report
المؤلفون: Bhatia, Harsharan Singh, Brunner, Andreas-David, Rong, Zhouyi, Mai, Hongcheng, Thielert, Marvin, Al-Maskari, Rami, Paetzold, Johannes Christian, Kofler, Florian, Todorov, Mihail Ivilinov, Ali, Mayar, Molbay, Muge, Kolabas, Zeynep Ilgin, Kaltenecker, Doris, Müller, Stephan, Lichtenthaler, Stefan F, Menze, Bjoern H, Theis, Fabian J, Mann, Matthias, Ertürk, Ali
المصدر: Bhatia, Harsharan Singh; Brunner, Andreas-David; Rong, Zhouyi; Mai, Hongcheng; Thielert, Marvin; Al-Maskari, Rami; Paetzold, Johannes Christian; Kofler, Florian; Todorov, Mihail Ivilinov; Ali, Mayar; Molbay, Muge; Kolabas, Zeynep Ilgin; Kaltenecker, Doris; Müller, Stephan; Lichtenthaler, Stefan F; Menze, Bjoern H; Theis, Fabian J; Mann, Matthias; Ertürk, Ali (2021). Proteomics of spatially identified tissues in whole organs. bioRxiv 466753, Cold Spring Harbor Laboratory.
مصطلحات موضوعية: Department of Quantitative Biomedicine, 610 Medicine & health
وصف الملف: application/pdf
Relation: https://www.zora.uzh.ch/id/eprint/220107/1/2021_preprint_Proteomics.pdf; urn:issn:2164-7844