المؤلفون: Evans, Caryl, Howells, Kathryn, Suzuki, Rie, Brown, Alastair J.H., Cox, Helen M.

المصدر: European Journal of Pharmacology ; volume 954, page 175897 ; ISSN 0014-2999

الاتاحة: http://dx.doi.org/10.1016/j.ejphar.2023.175897
https://api.elsevier.com/content/article/PII:S0014299923004089?httpAccept=text/xml
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المؤلفون: Nathan, Pradeep J., Millais, S. Babli, Godwood, Alex, Dewit, Odile, Cross, David M., Liptrot, Janet, Ruparelia, Bharat, Jones, Stephen Paul, Bakker, Geor, Maruff, Paul T., Light, Gregory A., Brown, Alastair J.H., Weir, Malcolm Peter, Congreve, Miles, Tasker, Tim

المصدر: Alzheimer's & Dementia: Translational Research & Clinical Interventions ; volume 8, issue 1 ; ISSN 2352-8737 2352-8737

الاتاحة: https://doi.org/10.1002/trc2.12273
https://onlinelibrary.wiley.com/doi/pdf/10.1002/trc2.12273
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المؤلفون: Nyimanu, Duuamene, Kay, Richard G., Kuc, Rhoda E., Brown, Alastair J.H., Gribble, Fiona M., Maguire, Janet J., Davenport, Anthony P.

المساهمون: Wellcome Trust, British Heart Foundation, University of Cambridge, UCLH Biomedical Research Centre

المصدر: Peptides ; volume 145, page 170642 ; ISSN 0196-9781

الاتاحة: http://dx.doi.org/10.1016/j.peptides.2021.170642
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المؤلفون: Brown, Alastair J.H., Bradley, Sophie J., Marshall, Fiona H., Brown, Giles A., Bennett, Kirstie A., Brown, Jason, Cansfield, Julie E., Cross, David M., de Graaf, Chris, Hudson, Brian D., Dwomoh, Louis, Dias, João M., Errey, James C., Hurrell, Edward, Liptrot, Jan, Mattedi, Giulio, Molloy, Colin, Nathan, Pradeep J., Okrasa, Krzysztof, Osborne, Greg, Patel, Jayesh C., Pickworth, Mark, Robertson, Nathan, Shahabi, Shahram, Bundgaard, Christoffer, Phillips, Keith, Broad, Lisa M., Goonawardena, Anushka V., Morairty, Stephen R., Browning, Michael, Perini, Francesca, Dawson, Gerard R., Deakin, John F.W., Smith, Robert T., Sexton, Patrick M., Warneck, Julie, Vinson, Mary, Tasker, Tim, Tehan, Benjamin G., Teobald, Barry, Christopoulos, Arthur, Langmead, Christopher J., Jazayeri, Ali, Cooke, Robert M., Rucktooa, Prakash, Congreve, Miles S., Weir, Malcolm, Tobin, Andrew B.

المصدر: Cell ; volume 184, issue 24, page 5886-5901.e22 ; ISSN 0092-8674

الاتاحة: http://dx.doi.org/10.1016/j.cell.2021.11.001
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المؤلفون: Soave, Mark, Cseke, Gabriella, Hutchings, Catherine J., Brown, Alastair J.H., Woolard, Jeanette, Hill, Stephen J.

المساهمون: Medical Research Council, Heptares Therapeutics Ltd., University of Nottingham

المصدر: Biochemical Pharmacology ; volume 147, page 38-54 ; ISSN 0006-2952

الاتاحة: http://dx.doi.org/10.1016/j.bcp.2017.10.015
https://api.elsevier.com/content/article/PII:S0006295217306469?httpAccept=text/xml
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المؤلفون: Graaf, Chris de, Donnelly, Dan, Wootten, Denise, Lau, Jesper, Sexton, Patrick M., Miller, Laurence J., Ahn, Jung-Mo, Liao, Jiayu, Fletcher, Madeleine M., Yang, Dehua, Brown, Alastair J.H., Zhou, Caihong, Deng, Jiejie, Wang, Ming-Wei

المصدر: Pharmacological Reviews ; volume 68, issue 4, page 954-1013 ; ISSN 0031-6997

الاتاحة: https://doi.org/10.1124/pr.115.011395
https://api.elsevier.com/content/article/PII:S0031699724012018?httpAccept=text/xml
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المؤلفون: Brown, Alastair J.H., Bradley, Sophie J., Marshall, Fiona H., Brown, Giles A., Bennett, Kirstie A., Brown, Jason, Cansfield, Julie E., Cross, David M., de Graaf, Chris, Hudson, Brian D., Dwomoh, Louis, Dias, João M., Errey, James C., Hurrell, Edward, Liptrot, Jan, Mattedi, Giulio, Molloy, Colin, Nathan, Pradeep J., Okrasa, Krzysztof, Osborne, Greg, Patel, Jayesh C., Pickworth, Mark, Robertson, Nathan, Shahabi, Shahram, Bundgaard, Christoffer, Phillips, Keith, Broad, Lisa M., Goonawardena, Anushka V., Morairty, Stephen R., Browning, Michael, Perini, Francesca, Dawson, Gerard R., Deakin, John F.W., Smith, Robert T., Sexton, Patrick M., Warneck, Julie, Vinson, Mary, Tasker, Tim, Tehan, Benjamin G., Teobald, Barry, Christopoulos, Arthur, Langmead, Christopher J., Jazayeri, Ali, Cooke, Robert M., Rucktooa, Prakash, Congreve, Miles S., Weir, Malcolm, Tobin, Andrew B.

Relation: Brown, A. J.H. et al. (2021) From structure to clinic: design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer’s disease. Cell , 184(24), 5886-5901.e22. (doi:10.1016/j.cell.2021.11.001 ) (PMID:34822784)

الاتاحة: https://eprints.gla.ac.uk/259498/

المؤلفون: Zaibi, Mohamed S., Stocker, Claire J., O'Dowd, Jacqueline, Davies, Alison, Bellahcene, Mohamed, Cawthorne, Michael A., Brown, Alastair J.H., Smith, David M., Arch, Jonathan R.S.

المصدر: FEBS Letters ; volume 584, issue 11, page 2381-2386 ; ISSN 0014-5793 1873-3468

الاتاحة: http://dx.doi.org/10.1016/j.febslet.2010.04.027
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المؤلفون: Brown, Alastair J.H., Perry, Stephen J., Saunders, Susan E., Burke, Julian F.

المصدر: BioTechniques ; volume 26, issue 5, page 804-806 ; ISSN 0736-6205 1940-9818

الاتاحة: http://dx.doi.org/10.2144/99265bm01
https://www.tandfonline.com/doi/pdf/10.2144/99265bm01

المؤلفون: O'Brien, Alistair, Andrews, Stephen P., Baig, Asma H., Bortolato, Andrea, Brown, Alastair J.H., Brown, Giles A., Brown, Sue H., Christopher, John A., Congreve, Miles, Cooke, Robert M., De Graaf, Chris, Errey, James C., Fieldhouse, Charlotte, Jazayeri, Ali, Marshall, Fiona H., Mason, Jonathan S., Mobarec, Juan Carlos, Okrasa, Krzysztof, Steele, Kelly N., Southall, Stacey M., Teobald, Iryna, Watson, Steve P., Weir, Malcolm

المساهمون: Biomedical Catalyst Award from Innovate

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 29, issue 20, page 126611 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2019.08.015
https://api.elsevier.com/content/article/PII:S0960894X19305426?httpAccept=text/xml
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المؤلفون: Erskine, Daniel, Taylor, John-Paul, Bakker, Geor, Brown, Alastair J.H., Tasker, Tim, Nathan, Pradeep J.

المساهمون: Alzheimer's Research UK, National Institute for Health Research

المصدر: Drug Discovery Today ; volume 24, issue 12, page 2307-2314 ; ISSN 1359-6446

الاتاحة: http://dx.doi.org/10.1016/j.drudis.2019.08.009
https://api.elsevier.com/content/article/PII:S1359644619303381?httpAccept=text/xml
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المؤلفون: Soave, Mark, Cseke, Gabriella, Hutchings, Catherine J., Brown, Alastair J.H., Woolard, Jeanette, Hill, Stephen J.

مصطلحات موضوعية: Monoclonal antibody, GPCR, Allosterism, Extracellular loop 2

وصف الملف: PDF

URL الوصول: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c1d11a4c0c43c09ee1135690f3667d84

المؤلفون: Cooke, Robert M., Brown, Alastair J.H., Marshall, Fiona H., Mason, Jonathan S.

المصدر: Drug Discovery Today ; volume 20, issue 11, page 1355-1364 ; ISSN 1359-6446

الاتاحة: http://dx.doi.org/10.1016/j.drudis.2015.08.003
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المؤلفون: Brown, Alastair J.H., Hutchings, Catherine, Burke, Julian F., Mayne, Lynne V.

المصدر: Methods in Enzymology ; cDNA Preparation and Characterization ; page 392-408 ; ISSN 0076-6879

الاتاحة: http://dx.doi.org/10.1016/s0076-6879(99)03024-4

المؤلفون: Sanganee, Hitesh J., Baxter, Andrew, Barber, Simon, Brown, Alastair J.H., Grice, Denise, Hunt, Fraser, King, Sarah, Laughton, David, Pairaudeau, Garry, Thong, Bob, Weaver, Richard, Unitt, John

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 19, issue 4, page 1143-1147 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2008.12.104
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