المؤلفون: Grzegorz A. Czapski, Marta Matuszewska, Magdalena Cieślik, Joanna B. Strosznajder

المصدر: Folia Neuropathologica, Vol 62, Iss 2, Pp 127-135 (2024)

مصطلحات موضوعية: alzheimer’s disease, systemic inflammatory response, endotoxin, bromodomain and extraterminal domain proteins, hippocampus, microglia, Medicine

وصف الملف: electronic resource

Relation: https://www.termedia.pl/Inhibitor-of-bromodomain-and-extraterminal-domain-proteins-decreases-transcription-of-Cd33-in-the-brain-of-mice-subjected-to-systemic-inflammation-a-promising-strategy-r-nfor-neuroprotection,20,53626,1,1.html; https://doaj.org/toc/1641-4640; https://doaj.org/toc/1509-572X

URL الوصول: https://doaj.org/article/62011e42640a4bb9963f78cda100833b

المؤلفون: Sears, Thomas K, Woolard, Kevin D

المصدر: Journal of Cancer Research and Clinical Oncology. 148(9)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Genetics, Orphan Drug, Cancer, Clinical Research, Brain Disorders, Neurosciences, Brain Cancer, 2.1 Biological and endogenous factors, Aetiology, Animals, Brain Neoplasms, Glioma, Isocitrate Dehydrogenase, Mutation, Nuclear Proteins, Transcription Factors, Bromodomain and extraterminal, Bromodomain inhibition, JQ1, Mutant isocitrate dehydrogenase 1/2, Oncology & Carcinogenesis, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6tz012gj
https://escholarship.org/content/qt6tz012gj/qt6tz012gj.pdf

المؤلفون: Toth, Peter P, Schwartz, Gregory G, Nicholls, Stephen J, Khan, Aziz, Szarek, Michael, Ginsberg, Henry N, Johansson, Jan O, Kalantar-Zadeh, Kamyar, Kulikowski, Ewelina, Lebioda, Ken, Wong, Norman CW, Sweeney, Michael, Ray, Kausik K, Investigators, BETonMACE

مصطلحات موضوعية: Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Cardiovascular, Chronic Liver Disease and Cirrhosis, Prevention, Liver Disease, Heart Disease, Clinical Trials and Supportive Activities, Clinical Research, Heart Disease - Coronary Heart Disease, Digestive Diseases, Atherosclerosis, Diabetes, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Good Health and Well Being, Apabetalone, Cardiovascular events, Fibrosis, Nonalcoholic fatty liver disease, BETonMACE Investigators, ACS, Acute coronary syndrome, ALP, Alkaline Phosphatase, ALT, Alanine aminotransferase, APR, Acute phase reactant, AST, Aspartate aminotransferase, ApoAI, Aproprotein-AI, BD, Bromodoamin, BET, Bromodomain and extraterminal proteinfamily, BMI, Body mass index, CV, Cardiovascular, CVD, Cardiovascular Disease, FS, Fibrosis score, HDL-C, High density lipoprotein cholesterol, HHF, Hospitalization for heart Failure, HR, Hazard ratio, MACE, Major acute coronary event, NAFLD, Nonalcoholic fatty liver disease, T2DM, Type 2 diabetes mellitus, Cardiovascular medicine and haematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7199f3f1

المؤلفون: Borthakur, Gautam, Odenike, Olatoyosi, Aldoss, Ibrahim, Rizzieri, David A, Prebet, Thomas, Chen, Chris, Popovic, Relja, Modi, Dimple A, Joshi, Rujuta H, Wolff, Johannes E, Jonas, Brian A

المصدر: Cancer. 127(16)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Clinical Research, Cancer, Orphan Drug, Pediatric Cancer, Hematology, Pediatric, Rare Diseases, Childhood Leukemia, 6.1 Pharmaceuticals, 5.1 Pharmaceuticals, Good Health and Well Being, Antineoplastic Combined Chemotherapy Protocols, Bridged Bicyclo Compounds, Heterocyclic, Humans, Leukemia, Myeloid, Acute, Pyridones, Sulfonamides, ABBV‐, 075, acute myeloid leukemia, bromodomain and extraterminal domain protein, mivebresib, phase 1 clinical trial, ABBV-075, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis, Public health

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1kf2n130
https://escholarship.org/content/qt1kf2n130/qt1kf2n130.pdf

المؤلفون: Goldin, Amanda N, Singh, Alok, Joshi, Shweta, Jamieson, Christina, Durden, Donald L

المصدر: Journal of Pediatric Hematology/Oncology. 43(3)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Pediatric Research Initiative, Pediatric, Pediatric Cancer, Stem Cell Research, Rare Diseases, Cancer, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Animals, Antineoplastic Agents, Cell Cycle Proteins, Cell Line, Tumor, Cell Survival, Chromones, Humans, Mice, Morpholines, Oligopeptides, Phosphoinositide-3 Kinase Inhibitors, Phosphorylation, Pyrans, Sarcoma, Ewing, Transcription Factors, Ewing sarcoma, dual inhibition, phosphoinositide-3 kinase (PI3K) pathway, bromodomain and extraterminal domain (BET) proteins, SF1126, SF2523, Cardiorespiratory Medicine and Haematology, Oncology & Carcinogenesis, Cardiovascular medicine and haematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5vm2r5rx

المؤلفون: Haarhaus, Mathias, Gilham, Dean, Kulikowski, Ewelina, Magnusson, Per, Kalantar-Zadeh, Kamyar

المصدر: Current opinion in nephrology and hypertension. 29(1)

مصطلحات موضوعية: Humans, Cardiovascular Diseases, Alkaline Phosphatase, Epigenesis, Genetic, Gene Expression Regulation, Enzymologic, Renal Insufficiency, Chronic, Quinazolinones, Cardiovascular, Genetics, Kidney Disease, Clinical Research, Heart Disease, Renal and urogenital, Good Health and Well Being, alkaline phosphatase, apabetalone, bromodomain and extraterminal inhibition, chronic kidney disease, epigenetic, microRNA, vascular calcification, Clinical Sciences, Urology & Nephrology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/62170585

المؤلفون: Chris Corton, Jie Liu, Andrew Williams, Eunnara Cho, Carole Yauk

مصطلحات موضوعية: Toxicology (incl. clinical toxicology), epigenome, microarray, histone deacetylase, bromodomain and extraterminal family proteins

Relation: https://figshare.com/articles/presentation/A_Gene_Expression_Biomarker_Identifies_Inhibitors_of_Two_Classes_of_Epigenome_Effectors_in_a_Human_Microarray_Compendium/23280269

الاتاحة: https://doi.org/10.23645/epacomptox.23280269.v1
https://figshare.com/articles/presentation/A_Gene_Expression_Biomarker_Identifies_Inhibitors_of_Two_Classes_of_Epigenome_Effectors_in_a_Human_Microarray_Compendium/23280269

المؤلفون: Hua Yang, Li Wei, Yang Xun, Anping Yang, Hua You

المصدر: Molecular Therapy: Oncolytics, Vol 21, Iss , Pp 1-14 (2021)

مصطلحات موضوعية: glioma, bromodomain and extraterminal protein family, BRD4, small molecular inhibitors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770521000371; https://doaj.org/toc/2372-7705

URL الوصول: https://doaj.org/article/300fb4c22d8040d388e408f08050f6d3

المؤلفون: Martin V. Nguyen, Lydia Loof, Gerald S. Falchook

المصدر: Journal of Immunotherapy and Precision Oncology, Pp 16-22 (2020)

مصطلحات موضوعية: bromodomain and extraterminal domain, bromodomain and extraterminal inhibitor, cancer, clinical trial, review, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2666-2345; https://doaj.org/toc/2590-017X

URL الوصول: https://doaj.org/article/953c704e02074f5595cc1efcdade115b

المؤلفون: DoYeong Jeon, Nackhyoung Kim, Soo-Jong Um

المصدر: Biological and Pharmaceutical Bulletin. 2023, 46(1):12

المؤلفون: Fengchen Shen, Shougang Zhuang

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: histone acetylation, histone acetyltransferases, histone deacetylases, bromodomain and extraterminal proteins, renal fibrosis, epithelial-mesenchymal transition, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.760308/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/d6057582fad847759123626466b7680b

المؤلفون: Jessica Sriha, Caroline Louis-Brennetot, Cécile Pierre-Eugène, Sylvain Baulande, Virginie Raynal, Amira Kramdi, Igor Adameyko, Uwe Ernsberger, Thomas Deller, Olivier Delattre, Isabelle Janoueix-Lerosey, Hermann Rohrer

المصدر: Cancers; Volume 14; Issue 11; Pages: 2755

مصطلحات موضوعية: chromaffin cell, sympathetic, neuroblast, bromodomain and extraterminal (BET) protein, transcriptional cyclin-dependent kinase

وصف الملف: application/pdf

Relation: Pediatric Oncology; https://dx.doi.org/10.3390/cancers14112755

الاتاحة: https://doi.org/10.3390/cancers14112755

المؤلفون: Bagley, Joshua, Yan, Zhiqiang, Zhang, Wei, Wildonger, Jill, Jan, Lily, Jan, Yuh

المصدر: Genes & Development. 28(17)

مصطلحات موضوعية: dendrite morphogenesis, double bromodomain and extraterminal, epigenetics, female sterile 1 homeotic, histone acetylation, mechanosensory function, Animals, Dendrites, Drosophila Proteins, Drosophila melanogaster, Epigenesis, Genetic, Gene Expression Regulation, Developmental, Homeodomain Proteins, Humans, Mutation, Nuclear Proteins, Protein Binding, Protein Structure, Tertiary, Sensory Receptor Cells, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/57s6x8rt

المؤلفون: Mills, Richard J, Humphrey, Sean J, Fortuna, Patrick RJ, Lor, Mary, Foster, Simon R, Quaife-Ryan, Gregory A, Johnston, Rebecca L, Dumenil, Troy, Bishop, Cameron, Rudraraju, Rajeev, Rawle, Daniel J, Le, Thuy, Zhao, Wei, Engwerda, Christian R

مصطلحات موضوعية: Biological sciences, Biomedical and clinical sciences, Bromodomain and extraterminal family inhibitors, COVID-19, drug discovery, heart, inflammation

Relation: Cell; Mills, RJ; Humphrey, SJ; Fortuna, PRJ; Lor, M; Foster, SR; Quaife-Ryan, GA; Johnston, RL; Dumenil, T; Bishop, C; Rudraraju, R; Rawle, DJ; Le, T; Zhao, W; Engwerda, CR; et al., BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection., Cell, 2021, 184 (8), pp. 2167-2182.e22; http://hdl.handle.net/10072/404132

الاتاحة: http://hdl.handle.net/10072/404132
https://doi.org/10.1016/j.cell.2021.03.026

المؤلفون: Rosemarie Tremblay-LeMay, Nasrin Rastgoo, Hong Chang

المصدر: Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-16 (2018)

مصطلحات موضوعية: Immune checkpoint inhibitors, PD-L1, PD-1, Multiple myeloma, Histone deacetylase, Bromodomain and extraterminal inhibitors, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13045-018-0589-1; https://doaj.org/toc/1756-8722

URL الوصول: https://doaj.org/article/9742b974e87f424e9309268b742a91ad

المؤلفون: Hu, Xiao, Schewitz-Bowers, Lauren, Lait, Philippa, Copland, Dave, Stimpson, Madeleine, Li, Jing Jing, Liu, Yizhi, Dick, Andrew, Lee, Richard, Wei, Lai

المصدر: Hu , X , Schewitz-Bowers , L , Lait , P , Copland , D , Stimpson , M , Li , J J , Liu , Y , Dick , A , Lee , R & Wei , L 2019 , ' The Bromodomain and Extra-Terminal Protein Inhibitor OTX015 Suppresses T Helper Cell Proliferation and Differentiation ' , Current Molecular Medicine , vol. 18 , no. 9 , pp. 594-601 . https://doi.org/10.2174/1566524019666190126112238

مصطلحات موضوعية: antiproliferation, Autoimmune disease, bromodomain and extraterminal domain (BET) inhibitors, CD4+ T cells, epigenetics, immunosuppression., OTX015

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/1983/04683b91-2893-448a-b201-173d44468e33
https://research-information.bris.ac.uk/en/publications/04683b91-2893-448a-b201-173d44468e33
https://doi.org/10.2174/1566524019666190126112238
https://research-information.bris.ac.uk/ws/files/186880601/Lai_MS_text_RL.pdf
https://research-information.bris.ac.uk/ws/files/186880602/Lai_supple_figures.pdf
https://research-information.bris.ac.uk/ws/files/186880603/Lai_figures.pdf
http://www.scopus.com/inward/record.url?scp=85062195212&partnerID=8YFLogxK

المؤلفون: Thao N.D. Pham, Sophie Stempel, Mario A. Shields, Christina Spaulding, Krishan Kumar, David J. Bentrem, Maria Matsangou, Hidayatullah G. Munshi

المصدر: International Journal of Molecular Sciences; Volume 20; Issue 17; Pages: 4293

مصطلحات موضوعية: flavonoids, quercetin, bromodomain and extraterminal domain (BET) inhibitors, combination therapy, pancreatic cancer, thyroid cancer, heterogeneous nuclear nucleoprotein A1 (hnRNPA1), survivin

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Bioactives and Nutraceuticals; https://dx.doi.org/10.3390/ijms20174293

الاتاحة: https://doi.org/10.3390/ijms20174293

المؤلفون: Jaydeep Bhat, Léonce Kouakanou, Christian Peters, Zhinan Yin, Dieter Kabelitz

المصدر: Frontiers in Immunology, Vol 9 (2018)

مصطلحات موضوعية: Bromodomain and ExtraTerminal domain, checkpoint inhibitors, DNA methylation, gamma delta T cells, histone acetylation, immunotherapy, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2018.00512/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/1e7112c05d814756a1c87538cc9c87c1

المؤلفون: Hu, X, Schewitz-Bowers, LP, Lait, PJP, Copland, DA, Stimpson, ML, Li, JJ, Liu, Y, Dick, AD, Lee, RWJ, Wei, L

المصدر: Current Molecular Medicine , 18 (9) pp. 594-601. (2018)

مصطلحات موضوعية: Autoimmune disease, CD4+ T cells, OTX015, antiproliferation, bromodomain and extraterminal domain (BET) inhibitors, epigenetics, immunosuppression

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10068127/1/Dick%20Lai%20MS%20text_RL.pdf; https://discovery.ucl.ac.uk/id/eprint/10068127/7/Dick%20Lai%20supple%20figures.pdf; https://discovery.ucl.ac.uk/id/eprint/10068127/13/Dick%20Lai%20figures.pdf; https://discovery.ucl.ac.uk/id/eprint/10068127/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10068127/1/Dick%20Lai%20MS%20text_RL.pdf
https://discovery.ucl.ac.uk/id/eprint/10068127/7/Dick%20Lai%20supple%20figures.pdf
https://discovery.ucl.ac.uk/id/eprint/10068127/13/Dick%20Lai%20figures.pdf
https://discovery.ucl.ac.uk/id/eprint/10068127/

المؤلفون: Ehrenhofer-Wolfer, K., Puchner, T., Schwarz, C., Rippka, J., Blaha-Ostermann, S., Strobl, U., Hormann, A., Bader, G., Kornigg, S., Zahn, S., Sommergruber, W., Schweifer, N., Zichner, T., Schlattl, A., Neumuller, R. A., Shi, J., Vakoc, C. R., Kogl, M., Petronczki, M., Kraut, N., Pearson, M. A., Wohrle, S.

مصطلحات موضوعية: bioinformatics, cancer, DNA, RNA structure, function, modification, diseases & disorders, genetics & nucleic acid processing, genomics and proteomics, Investigative techniques and equipment, neoplasms, protein structure, bromodomain and extraterminal protein, cell line, cell types, cell types and functions, CRISPR-Cas9, enzymes, gene expression, genes, structure and function, helicase, organs, tissues, organelles, protein types, transcription factor

وصف الملف: application/pdf

Relation: https://repository.cshl.edu/id/eprint/38301/1/2019.Ehrenhofer.SMARCA2.pdf; Ehrenhofer-Wolfer, K., Puchner, T., Schwarz, C., Rippka, J., Blaha-Ostermann, S., Strobl, U., Hormann, A., Bader, G., Kornigg, S., Zahn, S., Sommergruber, W., Schweifer, N., Zichner, T., Schlattl, A., Neumuller, R. A., Shi, J., Vakoc, C. R., Kogl, M., Petronczki, M., Kraut, N., Pearson, M. A., Wohrle, S. (August 2019) SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines. Sci Rep, 9 (1). p. 11661. ISSN 2045-2322

الاتاحة: https://repository.cshl.edu/id/eprint/38301/
https://repository.cshl.edu/id/eprint/38301/1/2019.Ehrenhofer.SMARCA2.pdf
https://www.ncbi.nlm.nih.gov/pubmed/31406271
https://doi.org/10.1038/s41598-019-48152-x