المؤلفون: Claire Marquilly, Germain U Busto, Brittany S Leger, Ana Boulanger, Edward Giniger, James A Walker, Lee G Fradkin, Jean-Maurice Dura

المصدر: PLoS Genetics, Vol 17, Iss 1, p e1009287 (2021)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/efc38108467142319cba47af0ac17410

المؤلفون: Sarah N. Wright, Brittany S. Leger, Sara Brin Rosenthal, Sophie N. Liu, Tongqiu Jia, Apurva S. Chitre, Oksana Polesskaya, Katie Holl, Jianjun Gao, Riyan Cheng, Angel Garcia Martinez, Anthony George, Alexander F. Gileta, Wenyan Han, Alesa H. Netzley, Christopher P. King, Alexander Lamparelli, Connor Martin, Celine L. St. Pierre, Tengfei Wang, Hannah Bimschleger, Jerry Richards, Keita Ishiwari, Hao Chen, Shelly B. Flagel, Paul Meyer, Terry E. Robinson, Leah C. Solberg Woods, Jason F. Kreisberg, Trey Ideker, Abraham A. Palmer

المصدر: Cell Reports, Vol 42, Iss 8, Pp 112873- (2023)

مصطلحات موضوعية: CP: Genomics, Biology (General), QH301-705.5

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723008847; https://doaj.org/toc/2211-1247; https://doaj.org/article/40d23e0993024b1ea31e653650c9f892

الاتاحة: https://doi.org/10.1016/j.celrep.2023.112873
https://doaj.org/article/40d23e0993024b1ea31e653650c9f892

المؤلفون: Vedagopuram Sreekanth, Qingxuan Zhou, Praveen Kokkonda, Heysol C. Bermudez-Cabrera, Donghyun Lim, Benjamin K. Law, Benjamin R. Holmes, Santosh K. Chaudhary, Rajaiah Pergu, Brittany S. Leger, James A. Walker, David K. Gifford, Richard I. Sherwood, Amit Choudhary

المصدر: ACS Central Science, Vol 6, Iss 12, Pp 2228-2237 (2020)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2374-7951

URL الوصول: https://doaj.org/article/f59a8cf4db8b44faa234b0cf6a54c506

المؤلفون: Víctor López Del Amo, Brittany S. Leger, Kurt J. Cox, Shubhroz Gill, Alena L. Bishop, Garrett D. Scanlon, James A. Walker, Valentino M. Gantz, Amit Choudhary

المصدر: Cell Reports, Vol 31, Iss 13, Pp 107841- (2020)

مصطلحات موضوعية: gene drive, split gene drive, CopyCat, super-Mendelian, small molecule, drug control, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720308226; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/df15ab12cf9c4df997f1b386eee938d8

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/Structure_and_overexpression_of_the_Abl_protein_/13610272

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.s002

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/The_loss_of_i_htt_i_rescues_the_i_Appl_i_sup_i_d_i_sup_MB_axon_outgrowth_mutant_phenotype_/13610284

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g001

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/_i_htt_i_interaction_with_i_Abl_i_/13610278

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.s004

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/_i_Abl_i_loss_of_function_in_MBs_/13610275

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.s003

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/The_overexpression_of_i_Abl_i_rescues_the_i_Appl_i_sup_i_d_i_sup_and_the_i_dsh_i_sup_i_1_i_sup_mutant_phenotypes_/13610269

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.s001

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/The_loss_of_i_htt_i_rescues_the_i_dsh_i_sup_i_1_i_sup_MB_axon_outgrowth_mutant_phenotype_/13610287

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g002

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/Detection_of_the_Abl-FRET_biosensor_in_the_MBs_/13610281

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.s005

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/Either_loss_or_overexpression_of_i_Abl_i_affect_MB_neuron_morphology_/13610290

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g003

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/Reducing_i_htt_i_expression_increases_i_Abl_i_-FRET_biosensor_phosphorylation_state_during_MB_development_/13610296

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g005

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/_i_htt_i_does_not_seem_to_affect_the_quantity_of_ABL_in_the_MBs_or_the_total_levels_of_neuronal_Abl_in_i_Drosophila_i_/13610299

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g006

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/dataset/_i_Abl_i_mutant_MARCM_clones_/13610305

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.t001

المؤلفون: Claire Marquilly (10005217), Germain U. Busto (10005220), Brittany S. Leger (9656144), Ana Boulanger (154429), Edward Giniger (33714), James A. Walker (173225), Lee G. Fradkin (8790848), Jean-Maurice Dura (154438)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, vivo FRET-based measurements, axon outgrowth defects, htt, Appl, Abl kinase activity, Abl tyrosine kinase, modulates axon outgrowth, Drosophila APP ortholog, Abl activity, MB αβ neurons, Amyloid precursor protein

Relation: https://figshare.com/articles/figure/Htt_is_a_repressor_of_Abl_activity_required_for_Appl-induced_axonal_growth_/13610302

الاتاحة: https://doi.org/10.1371/journal.pgen.1009287.g007

المؤلفون: Lee G. Fradkin, Jean-Maurice Dura, Brittany S. Leger, Ana Boulanger, Germain U. Busto, Claire Marquilly, James A. Walker, Edward Giniger

المساهمون: Institut de génétique humaine (IGH), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), St James University Hospital, Massachusetts General Hospital [Boston], Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], University of Massachusetts Medical School [Worcester] (UMASS), University of Massachusetts System (UMASS), ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010)

المصدر: PLoS Genetics
PLoS Genetics, Public Library of Science, 2021, 17 (1), pp.e1009287. ⟨10.1371/journal.pgen.1009287⟩
PLoS Genetics, Vol 17, Iss 1, p e1009287 (2021)

مصطلحات موضوعية: Huntingtin, Mutant, Axonal Transport, 0302 clinical medicine, Animal Cells, Fluorescence Resonance Energy Transfer, Amyloid precursor protein, Axon, [SDV.BDD]Life Sciences [q-bio]/Development Biology, Neurons, Huntingtin Protein, 0303 health sciences, ABL, Effector, Drosophila Melanogaster, Eukaryota, Polyglutamine tract, 3. Good health, Cell biology, Phenotypes, Huntington Disease, Spectrophotometry, Hyperexpression Techniques, Cellular Types, HTT, Embryonic Development, Repressor, 03 medical and health sciences, Alzheimer Disease, Memory, Genetics, Humans, Molecular Biology Techniques, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Mushroom Bodies, Molecular Biology Assays and Analysis Techniques, fungi, Organisms, Biology and Life Sciences, Invertebrates, nervous system, Mutation, Nerve Degeneration, Animal Studies, FRET, Acyltransferases, 030217 neurology & neurosurgery, Appl signaling, Neuroscience, Cloning, Developmental Biology, Cancer Research, Life Cycles, [SDV]Life Sciences [q-bio], QH426-470, Fluorophotometry, axonal growth, Amyloid beta-Protein Precursor, Nerve Fibers, Spectrum Analysis Techniques, Larvae, hemic and lymphatic diseases, Drosophila Proteins, Genetics (clinical), biology, Chemistry, Animal Models, Insects, medicine.anatomical_structure, Experimental Organism Systems, Mushroom bodies, Drosophila, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Drosophila melanogaster, Signal transduction, Signal Transduction, Research Article, congenital, hereditary, and neonatal diseases and abnormalities, animal structures, Arthropoda, Research and Analysis Methods, Model Organisms, mental disorders, Gene Expression and Vector Techniques, medicine, Animals, Learning, Kinase activity, 030304 developmental biology, Cell Biology, biology.organism_classification, mushroom body, Axons, Cellular Neuroscience, biology.protein, Zoology, Entomology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64396ad1ad999b4c6e36846bd94293a
https://hal.archives-ouvertes.fr/hal-02401010/document

المؤلفون: Alena L. Bishop, Valentino M. Gantz, Garrett D. Scanlon, James A. Walker, Víctor López del Amo, Amit Choudhary, Shubhroz Gill, Brittany S. Leger, Kurt J. Cox

المصدر: Cell Reports, Vol 31, Iss 13, Pp 107841-(2020)
Cell reports

مصطلحات موضوعية: 0301 basic medicine, Computer science, Population, Inheritance Patterns, CopyCat, small molecule, Computational biology, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Animals, Genetically Modified, Small Molecule Libraries, 03 medical and health sciences, symbols.namesake, 0302 clinical medicine, Drug control, CRISPR-Associated Protein 9, Animals, CRISPR, education, Control (linguistics), lcsh:QH301-705.5, Gene, 030304 developmental biology, education.field_of_study, super-Mendelian, 0303 health sciences, drug control, Cas9, Gene Drive Technology, Inheritance (genetic algorithm), Gene drive, Small molecule, Drosophila melanogaster, 030104 developmental biology, Pharmaceutical Preparations, lcsh:Biology (General), Mendelian inheritance, symbols, gene drive, Chemical control, split gene drive, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2849d5ebc21e377da23d3037cb7eff7e
https://doi.org/10.1101/665620