المؤلفون: Hao Xu, Kyler Pugh, Brian S. J. Blagg

المصدر: ACS Omega, Vol 10, Iss 1, Pp 449-455 (2025)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2470-1343

URL الوصول: https://doaj.org/article/675191a575744023a9df46e46959c268

المؤلفون: David I. Duron, Parthasaradhireddy Tanguturi, Christopher S. Campbell, Kerry Chou, Paul Bejarano, Katherin A. Gabriel, Jessica L. Bowden, Sanket Mishra, Christopher Brackett, Deborah Barlow, Karen L. Houseknecht, Brian S. J. Blagg, John M. Streicher

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)

مصطلحات موضوعية: Heat shock protein 90, Opioid, Anti-nociception, Reward, Constipation, Tolerance, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/224dd647f0154ca4bb4c8f2811b73164

المؤلفون: Amanda G. Smith, Valentin M. Kliebe, Sanket Mishra, Ryan P. McCall, Megan M. Irvine, Brian S. J. Blagg, Wei Lei

المصدر: Frontiers in Molecular Biosciences, Vol 11 (2024)

مصطلحات موضوعية: heat shock protein 90, microglial cell, inflammation, pain, LPS, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2024.1405339/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/086fa855d2da4cde8523b71a382fcb37

المؤلفون: Ranu Pal, Dongwei Hui, Heather Menchen, Huiping Zhao, Olivier Mozziconacci, Heather Wilkins, Brian S. J. Blagg, Christian Schöneich, Russell H. Swerdlow, Mary L. Michaelis, Elias K. Michaelis

المصدر: Frontiers in Aging Neuroscience, Vol 15 (2023)

مصطلحات موضوعية: Novobiocin analog, superoxide, mitochondria, complex I, pyruvate dehydrogenase kinase, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1282855/full; https://doaj.org/toc/1663-4365

URL الوصول: https://doaj.org/article/5aeb2462e3fd4a9d87dd8dfe62c1225c

المؤلفون: Sharif Rahmy, Sanket J. Mishra, Sean Murphy, Brian S. J. Blagg, Xin Lu

المصدر: Frontiers in Immunology, Vol 13 (2022)

مصطلحات موضوعية: heat shock protein 90 (hsp90), isoform-selective inhibitor, immune checkpoint blockade (ICB), prostate cancer, breast cancer, CDK4/6, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1005045/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/6beeabc616a9462799decbd31aa4768c

المؤلفون: Chitra Subramanian, Patrick T. Grogan, Ton Wang, Joseph Bazzill, Ang Zuo, Peter T. White, Avinaash Kalidindi, Dawn Kuszynski, Grace Wang, Brian S. J. Blagg, Mark S. Cohen

المصدر: Molecular Oncology, Vol 14, Iss 9, Pp 2058-2068 (2020)

مصطلحات موضوعية: heat shock protein 90 inhibitor, triple‐negative breast cancer, tumor‐initiating cells, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

URL الوصول: https://doaj.org/article/b903ea765283488cbf81ea52f406e330

المؤلفون: Margaret J. Hilton, Christopher M. Brackett, Brandon Q. Mercado, Brian S. J. Blagg, Scott J. Miller

المصدر: ACS Central Science, Vol 6, Iss 3, Pp 426-435 (2020)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2374-7951

URL الوصول: https://doaj.org/article/986b843fd1014d7e9f8d040931a52f63

المؤلفون: Anuj Khandelwal, Caitlin N. Kent, Maurie Balch, Shuxia Peng, Sanket J. Mishra, Junpeng Deng, Victor W. Day, Weiya Liu, Chitra Subramanian, Mark Cohen, Jeffery M. Holzbeierlein, Robert Matts, Brian S. J. Blagg

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/22d6d57dbf0548efa5ef84106a4676a4

المؤلفون: Wei Lei, David I. Duron, Carrie Stine, Sanket Mishra, Brian S. J. Blagg, John M. Streicher

المصدر: Frontiers in Molecular Neuroscience, Vol 12 (2019)

مصطلحات موضوعية: heat shock protein 90 (Hsp90), p23, Cdc37, opioid, pain, anti-nociception, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnmol.2019.00294/full; https://doaj.org/toc/1662-5099

URL الوصول: https://doaj.org/article/9fc67b842b574c10b83d599bf299a5bc

المؤلفون: Jason Davenport, Maurie Balch, Lakshmi Galam, Antwan Girgis, Jessica Hall, Brian S. J. Blagg, Robert L. Matts

المصدر: Biology, Vol 3, Iss 1, Pp 101-138 (2014)

مصطلحات موضوعية: Hsp90, Hsp90 inhibitors, high-throughput screen, natural products libraries, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.mdpi.com/2079-7737/3/1/101; https://doaj.org/toc/2079-7737

URL الوصول: https://doaj.org/article/1350f5985b8c413d9b00515bd4cba1f8

المؤلفون: Johannes Buchner, Milad J Alasady, Sarah J Backe, Brian S J Blagg, Richard L Carpenter, Giorgio Colombo, Ioannis Gelis, Daniel T Gewirth, Lila M Gierasch, Walid A Houry, Chrisostomos Prodromou

مصطلحات موضوعية: Biological sciences, Biochemistry and cell biology, 3101 Biochemistry and Cell Biology, 31 Biological Sciences, 0601 Biochemistry and Cell Biology, Biochemistry & Molecular Biology

Relation: 10779/uos.26385451.v1; https://figshare.com/articles/journal_contribution/_Editorial_Second_international_symposium_on_the_chaperone_code_2023/26385451

الاتاحة: https://figshare.com/articles/journal_contribution/_Editorial_Second_international_symposium_on_the_chaperone_code_2023/26385451

المؤلفون: Verodia Charlestin, Elijah Tan, Carlos Eduardo Arias-Matus, Junmin Wu, Maria Cristina Miranda-Vergara, Mijoon Lee, Man Wang, Dharma T. Nannapaneni, Parinda Tennakoon, Brian S. J. Blagg, Brandon L. Ashfeld, William Kaliney, Jun Li, Laurie E. Littlepage

المصدر: Cancers, Vol 16, Iss 15, p 2714 (2024)

مصطلحات موضوعية: aquaporin, breast cancer, inhibitor, Auphen, Z433927330, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: https://www.mdpi.com/2072-6694/16/15/2714; https://doaj.org/toc/2072-6694; https://doaj.org/article/dfcefb0001684cc0b5e9f3e73a405eb3

الاتاحة: https://doi.org/10.3390/cancers16152714
https://doaj.org/article/dfcefb0001684cc0b5e9f3e73a405eb3

المؤلفون: Michael A. Serwetnyk, Vincent M. Crowley, Christopher M. Brackett, Trever R. Carter, Asif Elahi, Vamsi Krishna Kommalapati, Ahmed Chadli, Brian S. J. Blagg

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, numerous oncogenic pathways, biologically active conformation, novel hsp90 inhibitors, negative breast cancer, various toxicities, structural modifications, structural features, simultaneously shut, nascent polypeptides, molecular chaperone, modulate triple, hsp90 inhibition, failed due, client substrates, branching moieties, alternative way, adverse events, 90 kilo

Relation: https://figshare.com/articles/journal_contribution/Enniatin_A_Analogues_as_Novel_Hsp90_Inhibitors_that_Modulate_Triple-Negative_Breast_Cancer/24582212

الاتاحة: https://doi.org/10.1021/acsmedchemlett.3c00423.s001
https://figshare.com/articles/journal_contribution/Enniatin_A_Analogues_as_Novel_Hsp90_Inhibitors_that_Modulate_Triple-Negative_Breast_Cancer/24582212

المؤلفون: Yini Zhu, Yun Zhao, Jiling Wen, Sheng Liu, Tianhe Huang, Ishita Hatial, Xiaoxia Peng, Hawraa Al Janabi, Gang Huang, Jackson Mittlesteadt, Michael Cheng, Atul Bhardwaj, Brandon L. Ashfeld, Kenneth R. Kao, Dean Y. Maeda, Xing Dai, Olaf Wiest, Brian S. J. Blagg, Xuemin Lu, Liang Cheng, Jun Wan, Xin Lu

مصطلحات موضوعية: Biological sciences, A1R confocal laser microscope, Immunohistochemistry (IHC) and Immunofluorescence (IF), cryosection, FFPE section, Prostate cancer, Animals, CD8-Positive T-Lymphocytes, Chromatin / metabolism, Humans, Immunotherapy, Intracellular Signaling Peptides and Protiens / genetics, Male, Mice, Transgenic, Prostatic Neoplasms* / genetics, Prostatic Neoplasms* / metabolism, Prostatic Neoplasms* / pathology, T-Lymphocytes, Cytotoxic, Tumor Microenvironment

Relation: https://figshare.com/articles/journal_contribution/Targeting_the_chromatin_effector_Pygo2_promotes_cytotoxic_T_cell_responses_and_overcomes_immunotherapyresistance_in_prostate_cancer_/24974952

الاتاحة: https://doi.org/10.7274/24974952.v1
https://figshare.com/articles/journal_contribution/Targeting_the_chromatin_effector_Pygo2_promotes_cytotoxic_T_cell_responses_and_overcomes_immunotherapyresistance_in_prostate_cancer_/24974952

المؤلفون: Yssa A. Rodriguez (11224111), Sukmanjit Kaur (11224114), Erika Nolte (11224117), Zhang Zheng (10491440), Brian S. J. Blagg (8480076), Rick T. Dobrowsky (1353135)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Marine Biology, Science Policy, Chemical Sciences not elsewhere classified, nerve conduction dysfunctions, MQC, mitophagy, mCherry-GFP fusion protein, KU -596 therapy, mtBE, Diabetic Sensory Neurons Diabetic, heat shock protein 70, KU -596 treatment, Hsp 70-, mitochondrial, Txnip-dependent manner, KU -596, KO, decrease mitophagic clearance, Novologue Therapy Requires Heat Sho., DPN, diabetes

Relation: https://figshare.com/articles/journal_contribution/Novologue_Therapy_Requires_Heat_Shock_Protein_70_and_Thioredoxin-Interacting_Protein_to_Improve_Mitochondrial_Bioenergetics_and_Decrease_Mitophagy_in_Diabetic_Sensory_Neurons/15097135

الاتاحة: https://doi.org/10.1021/acschemneuro.1c00340.s001

المؤلفون: Dilip K. Tosh (1668115), Christopher M. Brackett (6640094), Young-Hwan Jung (3908977), Zhan-Guo Gao (117989), Monimoy Banerjee (2048698), Brian S. J. Blagg (8480076), Kenneth A. Jacobson (117993)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, exhibit isoform selectivity, ATP binding site, Grp 94-Selective Inhibitors, adenosine receptor agonist, heat shock protein 90 kDa, inhibitor, NECA scaffold, Grp 94

Relation: https://figshare.com/articles/journal_contribution/Biological_Evaluation_of_5_i_N_i_Ethylcarboxamido_adenosine_Analogues_as_Grp94-Selective_Inhibitors/14135472

الاتاحة: https://doi.org/10.1021/acsmedchemlett.0c00509.s001

المؤلفون: Amanda G. Smith, Valentin M. Kliebe, Sanket Mishra, Ryan P. McCall, Megan M. Irvine, Brian S. J. Blagg, Wei Lei

مصطلحات موضوعية: Biochemistry, Molecular Biology, Structural Biology, Enzymes, Protein Trafficking, Proteomics and Intermolecular Interactions (excl. Medical Proteomics), Receptors and Membrane Biology, Signal Transduction, Structural Biology (incl. Macromolecular Modelling), Synthetic Biology, heat shock protein 90, microglial cell, inflammation, pain, LPS

Relation: https://figshare.com/articles/figure/Image2_Anti-inflammatory_activities_of_novel_heat_shock_protein_90_isoform_selective_inhibitors_in_BV-2_microglial_cells_tif/25734726

الاتاحة: https://doi.org/10.3389/fmolb.2024.1405339.s002
https://figshare.com/articles/figure/Image2_Anti-inflammatory_activities_of_novel_heat_shock_protein_90_isoform_selective_inhibitors_in_BV-2_microglial_cells_tif/25734726

المؤلفون: Bradley M. Keegan, Brian S. J. Blagg

المصدر: ACS Chemical Biology. 18:184-192

مصطلحات موضوعية: Molecular Medicine, General Medicine, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0fe5f91c1e754670210aa1eec3a31e4d
https://doi.org/10.1021/acschembio.2c00854

المؤلفون: Sanket J. Mishra, Tyelor S. Reynolds, Taylor Merfeld, Maurie Balch, Shuxia Peng, Junpeng Deng, Robert Matts, Brian S. J. Blagg

المصدر: ACS Medicinal Chemistry Letters. 13:1870-1878

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1786b217d1aa75daf743896d3e39a5
https://doi.org/10.1021/acsmedchemlett.2c00327

المؤلفون: Tihomir Tomašič, Martina Durcik, Bradley M. Keegan, Darja Gramec Skledar, Živa Zajec, Brian S. J. Blagg, Sharon D. Bryant

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 18; Pages: 6898

مصطلحات موضوعية: allosteric, cancer, Hsp90, inhibitor, molecular dynamics, pharmacophores, virtual screening

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Informatics; https://dx.doi.org/10.3390/ijms21186898

الاتاحة: https://doi.org/10.3390/ijms21186898