المؤلفون: Fikru B. Bedada, Brian R. Thompson, Jennifer L. Mikkila, Sunny S.-K. Chan, Si Ho Choi, Erik A. Toso, Michael Kyba, Joseph M. Metzger

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/62a45a61bcc04174b4a0815bbbae4f4f

المؤلفون: Dongwoo Hahn, Joseph D. Quick, Brian R. Thompson, Adelyn Crabtree, Benjamin J. Hackel, Frank S. Bates, Joseph M. Metzger

المصدر: Skeletal Muscle, Vol 13, Iss 1, Pp 1-14 (2023)

مصطلحات موضوعية: Duchenne muscular dystrophy, Dystrophin, Skeletal muscle, Membrane stabilizing copolymer, Contractile function, Calcium handling, Diseases of the musculoskeletal system, RC925-935

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2044-5040

URL الوصول: https://doaj.org/article/da57e682a1cf408ca948d597d44b4ef7

المؤلفون: Ashley A. Martin, Brian R. Thompson, Jonathan P. Davis, Hluechy Vang, Dongwoo Hahn, Joseph M. Metzger

المصدر: Scientific Reports, Vol 12, Iss 1, Pp 1-20 (2022)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/bf804568712048748156ce414fabb013

المؤلفون: Tiffiny Rye-McCurdy, Erik D. Olson, Shuohui Liu, Christiana Binkley, Joshua-Paolo Reyes, Brian R. Thompson, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth

المصدر: Viruses, Vol 8, Iss 9, p 256 (2016)

مصطلحات موضوعية: Rous sarcoma virus (RSV), human immunodeficiency virus type 1 (HIV-1), Gag, Psi RNA (Ψ RNA), matrix (MA), nucleocapsid (NC), Microbiology, QR1-502

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1999-4915/8/9/256; https://doaj.org/toc/1999-4915

URL الوصول: https://doaj.org/article/9b7fc45d900d44db947c74bc881aebff

المؤلفون: Ashley A. Martin, Brian R. Thompson, Dongwoo Hahn, Addeli Bez Batti Angulski, Nora Hosny, Houda Cohen, Joseph M. Metzger

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 16223

مصطلحات موضوعية: cardiac muscle, troponin, myosin, myosin-binding protein c, titin, heart disease, sarcomere

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Biology; https://dx.doi.org/10.3390/ijms232416223

الاتاحة: https://doi.org/10.3390/ijms232416223

المؤلفون: Jingcheng Xiao, Jian Shi, Brian R. Thompson, David E. Smith, Tao Zhang, Hao-Jie Zhu

المصدر: Journal of Pharmaceutical Sciences. 111:2606-2613

مصطلحات موضوعية: Male, Genotype, Pharmacogenetics, Methylphenidate, Humans, Pharmaceutical Science, Drug Interactions, Female, Carboxylic Ester Hydrolases, Models, Biological

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8900fa78ed5c8963ebf56ed08b38b3
https://doi.org/10.1016/j.xphs.2022.04.019

المؤلفون: Anthony D. Vetter, Brian R. Thompson, Ashley A. Martin, Joseph M. Metzger, David D. Thomas

المصدر: J Mol Cell Cardiol

مصطلحات موضوعية: Male, Sarcomeres, 0301 basic medicine, Myofilament, Biosensing Techniques, macromolecular substances, Myosins, 030204 cardiovascular system & hematology, Ligands, Sarcomere, Article, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Myofibrils, Troponin I, Myosin, medicine, Animals, Myocytes, Cardiac, Molecular Biology, Actin, biology, Chemistry, Myocardium, Cardiac muscle, musculoskeletal system, Myocardial Contraction, Troponin, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Mutation, biology.protein, Biophysics, Female, Troponin C, Cardiology and Cardiovascular Medicine, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2605d2e703510126f7024df87b96f2
https://doi.org/10.1016/j.yjmcc.2020.07.012

المؤلفون: Fikru B. Bedada, Joseph M. Metzger, Jennifer L. Mikkila, Matthew Wheelwright, Mohammad A. Mandegar, Brian R. Thompson

المصدر: Stem Cells

مصطلحات موضوعية: Adult, 0301 basic medicine, Gene isoform, Induced Pluripotent Stem Cells, Biology, Sarcomere, Article, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Myosin, medicine, Humans, Protein Isoforms, Myocyte, Myocytes, Cardiac, Induced pluripotent stem cell, Gene Editing, Genome, Human, Myocardium, Troponin I, Cardiac muscle, Reproducibility of Results, Cell Differentiation, Cell Biology, Myocardial Contraction, Troponin, Cell biology, Phospholamban, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, cardiovascular system, biology.protein, Molecular Medicine, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07eca4aea092a8a3d78b63ad434e959e
https://doi.org/10.1002/stem.3235

المؤلفون: Ashley A. Martin, Brian R. Thompson, Joseph M. Metzger

المصدر: Biophysical Journal. 122:28a

مصطلحات موضوعية: Biophysics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e3154a9f3cae6ae23ac2a006cd47a359
https://doi.org/10.1016/j.bpj.2022.11.372

المؤلفون: Brian R. Thompson, Joseph M. Metzger, Ashley A. Martin

المصدر: Circulation Research. 129

مصطلحات موضوعية: Myosin-binding protein C, Physiology, Chemistry, Structure function, Biophysics, Cardiology and Cardiovascular Medicine, Biosensor, Sarcomere

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::88783fabe5b201bd1ac91869b7e3946d
https://doi.org/10.1161/res.129.suppl_1.123

المؤلفون: David Smith, Yongjun Hu, Brian R. Thompson

المصدر: Biochem Pharmacol

مصطلحات موضوعية: Male, 0301 basic medicine, Cell Membrane Permeability, Enterocyte, Administration, Oral, Pharmacology, Deoxycytidine, Oral Mucosal Absorption, Biochemistry, Article, Inhibitory Concentration 50, Mice, 03 medical and health sciences, 0302 clinical medicine, Equilibrative Nucleoside Transport Proteins, medicine, Animals, Mice, Inbred BALB C, Intestinal permeability, Dilazep, Chemistry, Cell Membrane, Membrane Transport Proteins, Apical membrane, medicine.disease, Gemcitabine, Bioavailability, Mice, Inbred C57BL, Perfusion, 030104 developmental biology, medicine.anatomical_structure, Intestinal Absorption, 030220 oncology & carcinogenesis, Female, Efflux, Nucleoside, Thymidine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c33e43284e692facd7a9ba82cde0e4
https://doi.org/10.1016/j.bcp.2019.06.013

المؤلفون: Jing Yang, Gianluigi Veglia, Joseph M. Metzger, Kailey J. Soller, Anthony D. Vetter, Brian R. Thompson, Michael T. Bowser

المصدر: Journal of Molecular and Cellular Cardiology. 130:1-9

مصطلحات موضوعية: 0301 basic medicine, Chemistry, Cell, RNA, 030204 cardiovascular system & hematology, Cell biology, Protein–protein interaction, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Cytoplasm, Nucleic acid, medicine, Myocyte, Cardiology and Cardiovascular Medicine, Molecular Biology, Intracellular, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::53ffa678cbada7dc27c7179125f28e00
https://doi.org/10.1016/j.yjmcc.2019.02.016

المؤلفون: Melissa K. Gardner, Hluechy X. Vang, Cody R. Hou, Rebecca R. Goldblum, Brian R. Thompson, Houda Cohen, Mark McClellan, Joseph M. Metzger, Kyle White

مصطلحات موضوعية: Contractility, Chemistry, Acetylation, Microtubule, Heart failure, Cardiac myocyte, medicine, Myocyte, Cytoskeleton, medicine.disease, medicine.disease_cause, Oxidative stress, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d9fe41126df468c15abb0b160b244d66
https://doi.org/10.1101/2020.06.30.174532

المؤلفون: David Smith, Jian Shi, Brian R. Thompson, Hao Jie Zhu

المصدر: Biochem Pharmacol

مصطلحات موضوعية: 0301 basic medicine, Antimetabolites, Antineoplastic, endocrine system diseases, Administration, Oral, Biological Availability, Pharmacology, Biochemistry, Deoxycytidine, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Pharmacokinetics, Drug Stability, In vivo, Oral administration, medicine, Animals, Prodrugs, Amino Acids, Nucleoside analogue, Molecular Structure, Chemistry, Esters, Prodrug, Gemcitabine, Bioavailability, Mice, Inbred C57BL, 030104 developmental biology, Jejunum, 030220 oncology & carcinogenesis, Injections, Intravenous, Nucleoside, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1466ae514336c0cbe7b1ea9244e3c3a5
https://pubmed.ncbi.nlm.nih.gov/32603666

المؤلفون: Brian R. Thompson, Gordon L. Amidon, Hao Jie Zhu, Jian Shi, Vikram M Shenoy, David Smith

المصدر: Molecular pharmaceutics. 17(5)

مصطلحات موضوعية: Proteomics, Pharmaceutical Science, Cell Cycle Proteins, 02 engineering and technology, 030226 pharmacology & pharmacy, Activation, Metabolic, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Drug Discovery, Animals, Humans, Prodrugs, Enzyme kinetics, Shotgun proteomics, chemistry.chemical_classification, Activity-based proteomics, Intracellular Signaling Peptides and Proteins, Serine hydrolase, Prodrug, 021001 nanoscience & nanotechnology, Neoplasm Proteins, Mice, Inbred C57BL, Enzyme, chemistry, Biochemistry, Caco-2, Valacyclovir, Molecular Medicine, Caco-2 Cells, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d01e323e196e5ba6d35d087c730bf6
https://pubmed.ncbi.nlm.nih.gov/32196348

المؤلفون: Joseph M. Metzger, Kyle White, Hluechy X. Vang, Samuel J. Gonzalez, Todd W. Markowski, LeeAnn Higgins, Rebecca R. Goldblum, Houda Cohen, Mark McClellan, Tzu Yi Yang, Brian R. Thompson, Melissa K. Gardner

المصدر: Dev Cell

مصطلحات موضوعية: Biology, medicine.disease_cause, Microtubules, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, Tubulin, Microtubule, Fluorescence microscope, medicine, Animals, Myocyte, Myocytes, Cardiac, Cysteine, Cytoskeleton, Molecular Biology, Heart Failure, Cardiac myocyte, Cell Biology, medicine.disease, Rats, Cell biology, Oxidative Stress, Microscopy, Fluorescence, Heart failure, biology.protein, Guanosine Triphosphate, Oxidation-Reduction, Oxidative stress, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6287bc0ea5b0135edd79e22c8c7132
https://doi.org/10.1016/j.devcel.2021.07.004

المؤلفون: Houda Cohen, Brian R. Thompson, Addeli Bez Batti Angulski, Joseph M. Metzger

المصدر: Methods in Molecular Biology ISBN: 9781493990290

مصطلحات موضوعية: Adult, 0301 basic medicine, Gene isoform, medicine.medical_specialty, Heart Ventricles, Parvalbumins, Genetic Vectors, Models, Biological, Article, Adenoviridae, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Calcium imaging, Calcium-binding protein, Internal medicine, medicine, Animals, Humans, Myocyte, Myocytes, Cardiac, Heart Failure, biology, business.industry, Calcium-Binding Proteins, Gene Transfer Techniques, Diastolic heart failure, medicine.disease, 030104 developmental biology, 030220 oncology & carcinogenesis, Heart failure, Mutation, biology.protein, Cardiology, Calcium, Female, business, Parvalbumin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6a62ee395671d39b2a5b900ca49811
https://doi.org/10.1007/978-1-4939-9030-6_12

المؤلفون: Brian R, Thompson, Kailey J, Soller, Anthony, Vetter, Jing, Yang, Gianluigi, Veglia, Michael T, Bowser, Joseph M, Metzger

المصدر: J Mol Cell Cardiol

مصطلحات موضوعية: Sarcomeres, Cytoplasm, RNA, Untranslated, Animals, Calcium, Myocytes, Cardiac, DNA, Myocardial Contraction, Article, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b6c6cd25abe326bfb1f55723c5c0e2a0
https://pubmed.ncbi.nlm.nih.gov/30849419

المؤلفون: Brian R. Thompson, Anthony D. Vetter, Jordan Sell, Yuk Y. Sham, Evelyne M. Houang, Joseph M. Metzger

مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Protein Conformation, alpha-Helical, Biophysics, macromolecular substances, Molecular Dynamics Simulation, Sarcomere, Cardiac Troponin complex, Contractility, Rats, Sprague-Dawley, 03 medical and health sciences, Protein structure, Heterotrimeric G protein, Troponin I, Myocyte, Animals, Humans, Molecular Machines, Motors, and Nanoscale Biophysics, Chemistry, musculoskeletal system, Myocardial Contraction, Rats, 030104 developmental biology, HEK293 Cells, cardiovascular system, Female, Troponin C, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c3f7172091c1b592fa5ac2d0add78c
https://europepmc.org/articles/PMC5954295/

المؤلفون: Joseph M. Metzger, Brian R. Thompson, Ashley A. Martin

المصدر: Biophysical Journal. 118:278a

مصطلحات موضوعية: Förster resonance energy transfer, medicine.anatomical_structure, Chemistry, Structure function, Biophysics, medicine, Skeletal muscle, Sarcomere

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5ca13ad1f147e7fcde075c0efb60c38b
https://doi.org/10.1016/j.bpj.2019.11.1592