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1
المؤلفون: Leandro de Souza Silva, Yen Anh H. Nguyen, Brian G. Monks, Catherine S. Forconi, Juliet N. Crabtree, Tomás Rodriguez, Nelsy De Paula Tamburro, Erik J. Sontheimer, Gabor L. Horvath, Zeinab Abdullah, Eicke Latz, Daniel R. Caffrey, Evelyn A. Kurt-Jones, Ricardo T. Gazzinelli, Katherine A. Fitzgerald, Douglas T. Golenbock
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2Academic Journal
المؤلفون: Cd-deficient Murine Macrophages, Kathryn J. Moore, Lorna P. Andersson, Robin R. Ingalls, Mason W. Freeman, Murine Macrophages, Brian G. Monks, Rui Li, M. Amin Arnaout, Douglas T. Golenbock
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.8970; http://www.jimmunol.org/content/165/8/4272.full.pdf
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3Academic Journal
المؤلفون: Cutting Edge, Cells That Carry, A Null Allele, Holger Heine, Carsten J. Kirschning, Egil Lien, Brian G, Mike Rothe, Douglas T. Golenbock, Brian G. Monks
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.328.2911; http://www.jimmunol.org/content/162/12/6971.full.pdf
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4Academic Journal
المؤلفون: Andra B. Schromm, Egil Lien, Jesse C. Chow, Atsutoshi Yoshimura, Holger Heine, Eicke Latz, Brian G. Monks, David A. Schwartz, Kensuke Miyake, Douglas T. Golenbock
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/fc/d9/J_Exp_Med_2001_Jul_2_194(1)_79-88.tar.gz
وصف الملف: application/zip
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5Academic Journal
المؤلفون: Sanjay Ram, Meabh Cullinane, Anna M. Blom, Sunita Gulati, Daniel P. Mcquillen, Brian G. Monks, Ryan Boden, Christopher Elkins, Michael K. Pangburn, Björn Dahlbäck, Peter A. Rice
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/d2/37/J_Exp_Med_2001_Feb_5_193(3)_281-296.tar.gz
وصف الملف: application/zip
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6Academic Journal
المؤلفون: Robin R. Ingalls, Brian G. Monks, Ricardo Savedra, William J. Christ
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.627.1147; http://folk.ntnu.no/terjee/im229805413o.pdf
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7
المؤلفون: Brian G. Monks, Katherine A. Fitzgerald, Te-Chen Tzeng, Anna M. Cerny, Donghai Wang, Stefan A. Schattgen, Eicke Latz, Douglas T. Golenbock
المصدر: Cell Reports, Vol 16, Iss 2, Pp 571-582 (2016)
مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Male, Stromal cell, Inflammasomes, Population, Gene Expression, Mice, Transgenic, Peritonitis, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Orthomyxoviridae Infections, Genes, Reporter, Streptococcal Infections, medicine, Animals, education, lcsh:QH301-705.5, Caspase, education.field_of_study, biology, Pyroptosis, Signal transducing adaptor protein, Inflammasome, Virology, Cell biology, CARD Signaling Adaptor Proteins, Mice, Inbred C57BL, 030104 developmental biology, lcsh:Biology (General), biology.protein, Female, Protein Multimerization, Inflammasome complex, 030215 immunology, medicine.drug
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8
المؤلفون: Alberto Visintin, Lisa A. Lewis, Makoto Ohnishi, Peter A. Rice, Jutamas Shaughnessy, George W. Reed, Magnus Unemo, Guillermo Madico, Xia-Hong Su, Douglas T. Golenbock, Brian G. Monks, Sarika Agarwal, Sunita Gulati, Sanjay Ram
المصدر: The Journal of Immunology. 196:1732-1740
مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Recombinant Fusion Proteins, Immunology, Antibiotics, Mutant, Biology, medicine.disease_cause, Article, Microbiology, Gonorrhea, Mice, 03 medical and health sciences, Complement inhibitor, 0302 clinical medicine, In vivo, Atypical hemolytic uremic syndrome, medicine, Animals, Humans, Immunology and Allergy, Mice, Inbred BALB C, Mutation, Flow Cytometry, medicine.disease, Virology, Neisseria gonorrhoeae, Immunoglobulin Fc Fragments, Complement system, Disease Models, Animal, 030104 developmental biology, Complement Factor H, Female, Immunotherapy, 030215 immunology
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9
المؤلفون: Simone Hornemann, Gudrun Engels, Philip M. Hansbro, Matthew Mangan, Christoph Brenker, Terje Espevik, Martin Fricke, Ashraf Al-Amoudi, Bernardo S. Franklin, Andrew G. Jarnicki, Dominic De Nardo, Adriano Aguzzi, Bernadette Jones, Ann Marshak-Rothstein, Patricia Busto, Eicke Latz, Brian G. Monks, Sandra R Mirandola, Lukas Bossaller, Sebastian Zimmer, Andrea Stutz, Mark Nordhoff, Wolfgang Kastenmüller, Jacqueline M Ratter, Reinhold E. Schmidt
المساهمون: University of Zurich, Latz, Eicke
المصدر: NATURE IMMUNOLOGY
Nature Immunology
Nature immunology 15(8), 727-737 (2014). doi:10.1038/ni.2913مصطلحات موضوعية: Inflammasomes, animal diseases, Interleukin-1beta, immunology [Signal Transduction], Apoptosis, immunology [Phagocytosis], Cell Communication, genetics [Carrier Proteins], Amino Acid Chloromethyl Ketones, immunology [Antibodies], Mice, immunology [Inflammation], Immunology and Allergy, genetics [Caspase 1], immunology [Interleukin-1beta], Mice, Knockout, Mice, Inbred BALB C, pharmacology [Amino Acid Chloromethyl Ketones], Caspase 1, Pyroptosis, hemic and immune systems, Inflammasome, immunology [Apoptosis], immunology [Cytoskeletal Proteins], immunology [Macrophages], Caspase Inhibitors, immunology [Caspase 1], Cell biology, Pseudomonas aeruginosa, 2723 Immunology and Allergy, immunology [Cell Communication], Signal transduction, medicine.symptom, tissues, Signal Transduction, medicine.drug, endocrine system, benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone, immunology [Pseudomonas Infections], Prions, Immunology, Nlrp3 protein, mouse, 10208 Institute of Neuropathology, 610 Medicine & health, Inflammation, Biology, pharmacology [Caspase Inhibitors], immunology [Pseudomonas aeruginosa], Antibodies, Autoimmune Diseases, AIM2, immunology [Autoimmune Diseases], Phagocytosis, NLR Family, Pyrin Domain-Containing 3 Protein, immunology [Autoantibodies], Extracellular, medicine, Animals, Humans, Pseudomonas Infections, ddc:610, genetics [Cytoskeletal Proteins], Autoantibodies, 2403 Immunology, Innate immune system, Macrophages, chemistry [Prions], eye diseases, immunology [Inflammasomes], Mice, Inbred C57BL, CARD Signaling Adaptor Proteins, Cytoskeletal Proteins, Pycard protein, mouse, 570 Life sciences, biology, Lysosomes, Carrier Proteins, Apoptosis Regulatory Proteins, pathology [Lysosomes]
وصف الملف: Franklin_NatureImm_2014.pdf - application/pdf; application/pdf
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10
المؤلفون: Andrea Stutz, Erik C. Hett, Kevin G. Mark, Deborah T. Hung, Louise H. Slater, Brian G. Monks, Eicke Latz, Tomohiko Kawate
المصدر: Nature chemical biology 9(6), 398-405 (2013). doi:10.1038/nchembio.1236
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Programmed cell death, Protein Conformation, Enzyme-Linked Immunosorbent Assay, enzymology [Bacillus anthracis], metabolism [Peptide Hydrolases], Biology, Models, Biological, Article, Cell Line, Mice, eIF-2 Kinase, RNA interference, ddc:570, Catalytic Domain, medicine, Animals, metabolism [Proteasome Endopeptidase Complex], HSP90 Heat-Shock Proteins, Kinase activity, Molecular Biology, Inflammation, Mice, Inbred BALB C, Cell Death, metabolism [HSP90 Heat-Shock Proteins], Kinase, Macrophages, metabolism [Caspase 1], Caspase 1, Pyroptosis, Inflammasome, Cell Biology, Hydrogen-Ion Concentration, Molecular biology, Protein kinase R, Cell biology, Bacillus anthracis, metabolism [Macrophages], chemistry [eIF-2 Kinase], Chemical genetics, Peptide Hydrolases, medicine.drug
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11
المؤلفون: Arnab Bhattacharjee, Gabor Horvath, Brian G. Monks, Joana Pedrosa, Connie Tran, Peter A. Rice, Jutamas Shaughnessy, Sanjay Ram, T. Sakari Jokiranta, Alberto Visintin
المصدر: Journal of Biological Chemistry. 286:22235-22242
مصطلحات موضوعية: Models, Molecular, Pan troglodytes, Molecular Sequence Data, Biology, Arginine, medicine.disease_cause, Microbiology, Biochemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Species Specificity, medicine, Animals, Humans, Amino Acid Sequence, Binding site, Molecular Biology, Peptide sequence, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Binding Sites, Heparin, Immunoglobulin Fc Fragments, Cell Biology, Fragment crystallizable region, Molecular biology, N-Acetylneuraminic Acid, Neisseria gonorrhoeae, Protein Structure, Tertiary, 3. Good health, Amino acid, Amino Acid Substitution, chemistry, Complement Factor H, Factor H, Mutation, Alternative complement pathway, Protein Binding, 030215 immunology
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12
المؤلفون: Lisa Waggoner, Leah E. Cole, Zhaozhao Jiang, Veit Hornung, Sivapriya Kailasan Vanaja, Katherine A. Fitzgerald, Vijay A. K. Rathinam, Stefanie N. Vogel, Brian G. Monks, Shrutie Sharma, Eva Szomolanyi-Tsuda, Sandhya Ganesan, Stephen N. Waggoner, Eicke Latz
المصدر: Nature immunology
مصطلحات موضوعية: Immunology, Caspase 1, Biology, Lymphocyte Activation, Virus, Article, Microbiology, Cell Line, 03 medical and health sciences, AIM2, Mice, 0302 clinical medicine, medicine, Immunology and Allergy, Animals, Humans, Listeriosis, Francisella tularensis, Tularemia, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Innate immune system, IFI16, Macrophages, Pyroptosis, DNA Viruses, Nuclear Proteins, Inflammasome, DNA, Viral Load, DNA Virus Infections, Immunity, Innate, 3. Good health, CARD Signaling Adaptor Proteins, DNA-Binding Proteins, Killer Cells, Natural, Mice, Inbred C57BL, Cytoskeletal Proteins, Viral replication, Multiprotein Complexes, Cytokines, Apoptosis Regulatory Proteins, 030215 immunology, medicine.drug, Signal Transduction, Transcription Factors
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13
المؤلفون: Jutamas Ngampasutadol, Brian G. Monks, Alberto Visintin, Sunita Gulati, Chongqing Li, Sarika Agarwal, Sanjay Ram, Peter A. Rice, Guillermo Madico
المصدر: The Journal of Immunology. 180:3426-3435
مصطلحات موضوعية: Lipopolysaccharides, Blood Bactericidal Activity, Pan troglodytes, Amino Acid Motifs, Immunology, Oligosaccharides, Porins, medicine.disease_cause, Microbiology, Mice, Classical complement pathway, Species Specificity, medicine, Animals, Humans, Immunology and Allergy, Complement Pathway, Classical, Complement Inactivator Proteins, Innate immune system, biology, CD46, Macaca mulatta, Virology, Neisseria gonorrhoeae, Peptide Fragments, Complement system, Complement Factor H, Factor H, Host-Pathogen Interactions, Alternative complement pathway, biology.protein, Papio, Protein Binding, Complement control protein
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14
المؤلفون: Michael J. Primiano, Andrea G Bree, Paul D. Bonin, Aiping Jiao, Stephen W. J. Wang, J. Perry Hall, David Hepworth, Ken Dower, Julia A. Guzova, Bruce Allen Lefker, Cedric Hubeau, Eicke Latz, Leah Cushing, Brian G. Monks, Lih-Ling Lin, Michael R. Bowman, Matthew Mangan
المصدر: The journal of immunology 197(6), 2421-2433 (2016). doi:10.4049/jimmunol.1600035
مصطلحات موضوعية: 0301 basic medicine, Inflammasomes, Interleukin-1beta, Dermatitis, Pharmacology, Pathogenesis, Mice, immunology [Inflammation], Interleukin-1alpha, administration & dosage [Heterocyclic Compounds, 4 or More Rings], Immunology and Allergy, Medicine, metabolism [Interleukin-1alpha], therapeutic use [Sulfones], Sulfones, immunology [Interleukin-1beta], Sulfonamides, integumentary system, Interleukin-18, Inflammasome, administration & dosage [Sulfones], immunology [Pneumonia], Indenes, Cytokines, medicine.symptom, Signal transduction, pharmacology [Sulfones], medicine.drug, Signal Transduction, antagonists & inhibitors [Inflammasomes], Immunology, drug effects [Immunity, Innate], Inflammation, Heterocyclic Compounds, 4 or More Rings, Proinflammatory cytokine, physiopathology [Dermatitis], 03 medical and health sciences, In vivo, Immunity, antagonists & inhibitors [Interleukin-1alpha], drug therapy [Pneumonia], NLR Family, Pyrin Domain-Containing 3 Protein, Animals, Humans, ddc:610, Furans, antagonists & inhibitors [NLR Family, Pyrin Domain-Containing 3 Protein], Innate immune system, antagonists & inhibitors [Cytokines], business.industry, MCC-950, antagonists & inhibitors [Interleukin-1beta], drug therapy [Inflammation], Pneumonia, drug therapy [Dermatitis], therapeutic use [Heterocyclic Compounds, 4 or More Rings], physiopathology [Pneumonia], antagonists & inhibitors [Interleukin-18], Immunity, Innate, Disease Models, Animal, 030104 developmental biology, immunology [Cytokines], immunology [Dermatitis], metabolism [Interleukin-18], physiopathology [Inflammation], business, pharmacology [Heterocyclic Compounds, 4 or More Rings]
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15
المؤلفون: C. James McKnight, Terje Espevik, Dionne C.G. Klein, Alberto Visintin, Mei Gong, Anjali Verma, Cherilyn M. Sirois, W. Paul Duprex, Douglas T. Golenbock, Marc Lamphier, Brian G. Monks, Eicke Latz
المصدر: Nature Immunology. 8:772-779
مصطلحات موضوعية: Protein Conformation, Endosome, Immunology, Allosteric regulation, chemical and pharmacologic phenomena, Biology, Ligands, Cell Line, chemistry.chemical_compound, Allosteric Regulation, immune system diseases, parasitic diseases, Humans, Immunology and Allergy, TLR9, hemic and immune systems, Ligand (biochemistry), Cell biology, Toll-Like Receptor 9, Oligodeoxyribonucleotides, Ectodomain, Biochemistry, CpG site, chemistry, CpG Islands, sense organs, DNA, Protein Binding
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16
المؤلفون: Kristen A. Halmen, Alberto Visintin, Brian G. Monks, Naseema N. Khan, Egil Lien, Douglas T. Golenbock
المصدر: Journal of Leukocyte Biology. 80:1584-1592
مصطلحات موضوعية: Lipopolysaccharides, Immunology, Cell, Lymphocyte Antigen 96, Biology, Cell Line, Mice, Cell surface receptor, medicine, Animals, Humans, Immunology and Allergy, Mice, Knockout, Regulation of gene expression, Toll-like receptor, Innate immune system, Cell Biology, Molecular biology, Cell biology, Toll-Like Receptor 4, medicine.anatomical_structure, Gene Expression Regulation, Cell culture, Knockout mouse, TLR4, lipids (amino acids, peptides, and proteins)
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17Pharmacological Inhibition of Endotoxin Responses Is Achieved by Targeting the TLR4 Coreceptor, MD-2
المصدر: The Journal of Immunology. 175:6465-6472
مصطلحات موضوعية: Lipopolysaccharides, Receptor complex, Recombinant Fusion Proteins, Immunology, Lymphocyte Antigen 96, Endogeny, Stimulation, Biology, Molecular biology, Fusion protein, Cell Line, Protein Structure, Tertiary, Toll-Like Receptor 4, Kinetics, Lipid A, Solubility, Cell culture, TLR4, Humans, Immunology and Allergy, lipids (amino acids, peptides, and proteins), Avidity, Signal transduction, Protein Binding, Signal Transduction
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18
المؤلفون: Brian G. Monks, Alberto Visintin, Douglas T. Golenbock, Nadra J. Nilsen, Terje Espevik, Catherine F. Knetter, Egil Lien, Eicke Latz, Katherine A. Fitzgerald, Annett Schoenemeyer
المصدر: Nature Immunology. 5:190-198
مصطلحات موضوعية: Endosome, CpG Oligodeoxynucleotide, Recombinant Fusion Proteins, Immunology, Biological Transport, Active, Receptors, Cell Surface, chemical and pharmacologic phenomena, In Vitro Techniques, Biology, Endoplasmic Reticulum, Cell Line, Mice, immune system diseases, Lysosome, parasitic diseases, medicine, Animals, Humans, Immunology and Allergy, Receptors, Immunologic, Adaptor Proteins, Signal Transducing, Mice, Knockout, Membrane Glycoproteins, Endoplasmic reticulum, Toll-Like Receptors, TLR9, hemic and immune systems, Dendritic Cells, Antigens, Differentiation, Molecular biology, Toll-Like Receptor 9, DNA-Binding Proteins, Mice, Inbred C57BL, Luminescent Proteins, medicine.anatomical_structure, CpG site, Myeloid Differentiation Factor 88, CpG Islands, Signal transduction, Lysosomes, Signal Transduction
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19
المصدر: Journal of Biological Chemistry. 278:48313-48320
مصطلحات موضوعية: Lipopolysaccharides, Lymphocyte antigen 96, Blotting, Western, Molecular Sequence Data, Lipopolysaccharide Receptors, Lymphocyte Antigen 96, Receptors, Cell Surface, Biology, Transfection, Biochemistry, Cell Line, Humans, Biotinylation, Amino Acid Sequence, Cysteine, Receptor, Molecular Biology, Toll-like receptor, Membrane Glycoproteins, Sequence Homology, Amino Acid, Lysine, Cell Membrane, Toll-Like Receptors, Signal transducing adaptor protein, Cell Biology, Precipitin Tests, Recombinant Proteins, Protein Structure, Tertiary, Lipopolysaccharide binding, Cell biology, Toll-Like Receptor 4, Microscopy, Fluorescence, Antigens, Surface, Microscopy, Electron, Scanning, TLR4, Tyrosine, lipids (amino acids, peptides, and proteins), Signal transduction, Intracellular, Protein Binding, Signal Transduction
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20
المؤلفون: Luke A. J. O'Neill, Seth L. Masters, Kingston H. G. Mills, Jae Jin Chae, Mark S. Butler, Avril A. B. Robertson, Caroline E. Sutton, Raúl Muñoz-Planillo, Brian G. Monks, Gabriel Núñez, Daniel L. Kastner, Marco Inserra, Lara S. Dungan, Daniel E. Croker, Andrea Stutz, Rebecca C. Coll, Irina Vetter, Mark E. Cooper, Eicke Latz, Sarah C. Higgins, Moritz Haneklaus, Kate Schroder
المصدر: Nature medicine 21(3), 248-255 (2015). doi:10.1038/nm.3806
مصطلحات موضوعية: Multiple Sclerosis, antagonists & inhibitors [Inflammasomes], Inflammasomes, Interleukin-1beta, Nlrp3 protein, mouse, NALP3, Pyrin domain, Heterocyclic Compounds, 4 or More Rings, General Biochemistry, Genetics and Molecular Biology, AIM2, Mice, NLRC4, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, NLRP3 protein, human, Animals, Humans, therapeutic use [Sulfones], ddc:610, Sulfones, Furans, drug therapy [Cryopyrin-Associated Periodic Syndromes], Inflammation, Sulfonamides, integumentary system, biology, drug effects [Interleukin-1beta], Experimental autoimmune encephalomyelitis, MCC-950, Cryopyrin-associated periodic syndrome, Inflammasome, General Medicine, therapeutic use [Heterocyclic Compounds, 4 or More Rings], medicine.disease, Disease Models, Animal, Indenes, Immunology, IL1B protein, mouse, biology.protein, antagonists & inhibitors [Carrier Proteins], drug therapy [Encephalomyelitis, Autoimmune, Experimental], pharmacology [Sulfones], Carrier Proteins, NLRP3 inflammasome complex, pharmacology [Heterocyclic Compounds, 4 or More Rings], medicine.drug