المؤلفون: Ashutosh ePudasaini, Kaley K. El-Arab, Brian D. Zoltowski

المصدر: Frontiers in Molecular Biosciences, Vol 2 (2015)

مصطلحات موضوعية: Photobiology, Protein Engineering, optogenetics, photosensors, LOV domain, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00018/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/b7cbc09839fd4e4392018982f849a118

المؤلفون: Tingting Zhao, Nischal Karki, Brian D Zoltowski, Devin A Matthews

المصدر: PLoS Computational Biology, Vol 18, Iss 12, p e1010794 (2022)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/9330d525e6bc44c6a2c8c7a083cb93b1

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/journal_contribution/RMSD_and_RMSF_analysis_/21766182

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s001

المؤلفون: Francesco Trozzi, Feng Wang, Gennady Verkhivker, Brian D Zoltowski, Peng Tao

المصدر: PLoS Computational Biology, Vol 17, Iss 7, p e1009168 (2021)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/103680ec68754de2bfdd65f598f5b53f

المؤلفون: Francesco Trozzi (10782804), Feng Wang (44414), Gennady Verkhivker (265906), Brian D. Zoltowski (733287), Peng Tao (1338780)

مصطلحات موضوعية: Biophysics, Medicine, Cell Biology, Genetics, Physiology, Plant Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Information Systems not elsewhere classified, Dimeric allostery mechanism, plant circadian clock photoreceptor., ZTL allosteric mechanisms, allosteric mechanism, dynamics-driven allosteric pathways, residues G 46, LOV, protein, allosteric mechanism hinges

Relation: https://figshare.com/articles/journal_contribution/Protein_Stability_Analysis_/15056792

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009168.s024

المؤلفون: Francesco Trozzi, Nischal Karki, Zilin Song, Niraj Verma, Elfi Kraka, Brian D. Zoltowski, Peng Tao

المصدر: Org Biomol Chem

مصطلحات موضوعية: Binding Sites, Protein Domains, SARS-CoV-2, Organic Chemistry, Spike Glycoprotein, Coronavirus, COVID-19, Humans, Angiotensin-Converting Enzyme 2, Physical and Theoretical Chemistry, Molecular Dynamics Simulation, Biochemistry, Article, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b045a3e2ec4c4d18e1d18f5b60e7d69b
https://pubmed.ncbi.nlm.nih.gov/35420112

المؤلفون: Hongyu Zhou, Zheng Dong, Gennady Verkhivker, Brian D Zoltowski, Peng Tao

المصدر: PLoS Computational Biology, Vol 15, Iss 2, p e1006801 (2019)

مصطلحات موضوعية: Biology (General), QH301-705.5

Relation: https://doi.org/10.1371/journal.pcbi.1006801; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358; https://doaj.org/article/3e099f4a208b4e7394a468f0a9c7f785

الاتاحة: https://doi.org/10.1371/journal.pcbi.1006801
https://doaj.org/article/3e099f4a208b4e7394a468f0a9c7f785

المؤلفون: Ashutosh Pudasaini, Jae Sung Shim, Young Hun Song, Hua Shi, Takatoshi Kiba, David E Somers, Takato Imaizumi, Brian D Zoltowski

المصدر: eLife, Vol 6 (2017)

مصطلحات موضوعية: circadian clock, allostery, LOV domain, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/21646; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/63df3c18425d46d2ad0ec1a914335ec3

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/Secondary_structure_assigned_by_the_UniProt_database_by_compiling_structure_information_from_multiple_x-ray_crystal_structures_/21766185

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s002

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/Characterization_of_CCD_using_pair_C_i_i_distances_/21766194

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s005

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/Pair_C_i_i_distance_distribution_between_Q644_and_Y657_Q644_and_E638_of_6_replicas_for_wild_type_and_D170A_variant_/21766191

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s004

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/The_PCA_analysis_of_pair_distances_of_rigid_core_without_residue_562_residues_240_252_474_479_511_546_549_550_564_568_610_611_/21766200

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s007

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/CCD_i_i_3_global_tilt_angle_distribution_/21766203

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s008

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/Additional_REDAN_analysis_results_/21766209

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s009

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/The_mean_RMSF_of_six_replicates_was_plotted_with_the_RMSF_values_for_each_residue_separated_by_domain_/21766212

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s010

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/S11_Fig_-/21766224

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s013

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/Proposed_specific_mechanism_/21766215

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s011

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/Figure_depicting_the_simulation_system_generated_by_VMD_/21766227

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s014

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/Root_Mean_Square_Deviation_RMSD_analysis_/21766233

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.s015

المؤلفون: Tingting Zhao (1295883), Nischal Karki (9874044), Brian D. Zoltowski (733287), Devin A. Matthews (1359477)

مصطلحات موضوعية: Biophysics, Biochemistry, Cancer, Biological Sciences not elsewhere classified, transmits conformational changes, potential pharmaceutical control, molecular dynamics simulations, explore conformational space, delineate mechanistic differences, propose allosteric pathways, modulate sh2 binding, two stat3 domains, several ccd effectors, sh2 domains via, sh2 domain regulation, allosteric regulation, sh2 via, sh2 domain, wild type, viable target, transcription 3, therapeutic drugs, stat3 interdomains, stat3 functions, rigid core, range interactions, poorly understood, pharmacologic efficacy, linker domain, key target

Relation: https://figshare.com/articles/figure/STAT3_structure_/21766236

الاتاحة: https://doi.org/10.1371/journal.pcbi.1010794.g001