المؤلفون: Daniel W. Robbins, Mark A. Noviski, Ying Siow Tan, Zef A. Konst, Aileen Kelly, Paul Auger, Nivetha Brathaban, Robert Cass, Ming Liang Chan, Ganesh Cherala, Matthew C. Clifton, Stefan Gajewski, Timothy G. Ingallinera, Dane Karr, Daisuke Kato, Jun Ma, Jenny McKinnell, Joel McIntosh, Jeff Mihalic, Brent Murphy, Jaipal Reddy Panga, Ge Peng, Janine Powers, Luz Perez, Ryan Rountree, Austin Tenn-McClellan, Arthur T. Sands, Dahlia R. Weiss, Jeffrey Wu, Jordan Ye, Cristiana Guiducci, Gwenn Hansen, Frederick Cohen

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Cancer, Hematology, Infectious Diseases, Virology, Computational Biology, Chemical Sciences not elsewhere classified, transcription factors ikzf1, molecular glue interactions, human clinical trials, attractive therapeutic target, preclinical oncology models, many hematological malignancies, degradation across species, concomitant immunomodulatory activity, btk enzymatic function, orally bioavailable degrader, mediated bcr signaling, orally bioavailable, immunomodulatory activity, preclinical pharmacology, btk degrader, vivo <, tyrosine kinase

Relation: https://figshare.com/articles/journal_contribution/Discovery_and_Preclinical_Pharmacology_of_NX-2127_an_Orally_Bioavailable_Degrader_of_Bruton_s_Tyrosine_Kinase_with_Immunomodulatory_Activity_for_the_Treatment_of_Patients_with_B_Cell_Malignancies/25130114

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01007.s001
https://figshare.com/articles/journal_contribution/Discovery_and_Preclinical_Pharmacology_of_NX-2127_an_Orally_Bioavailable_Degrader_of_Bruton_s_Tyrosine_Kinase_with_Immunomodulatory_Activity_for_the_Treatment_of_Patients_with_B_Cell_Malignancies/25130114

المؤلفون: Hefei Liu, Praveen Nuksani, Malolan Rajagopalan, Mangesh Patil, Krishna Komanduri, Brent Murphy, Deepak Khuntia, Sushil Beriwal

المصدر: Medical Dosimetry. 48:51-54

مصطلحات موضوعية: Oncology, Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e147d81ca6ee0205235b45509772fea3
https://doi.org/10.1016/j.meddos.2022.10.003

المؤلفون: Matheus M. Noguera, Aimone Porri, Isabel S. Werle, James Heiser, Frank Brändle, Jens Lerchl, Brent Murphy, Michael Betz, Fanny Gatzmann, Martin Penkert, Clara Tuerk, Lucie Meyer, Nilda Roma-Burgos

المصدر: Planta. 256(3)

مصطلحات موضوعية: Amaranthus, Ammonia, Glutamate-Ammonia Ligase, Herbicides, Aminobutyrates, Genetics, Plant Science, Herbicide Resistance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8689d26ee5b57b31a5c732d49697e7
https://pubmed.ncbi.nlm.nih.gov/35960361

المؤلفون: Genevieve Hartley, Leone S. Hopkins, Steven W. Dow, Amanda Guth, Brent Murphy, Robyn E. Elmslie

المصدر: Veterinary and Comparative Oncology. 17:69-79

مصطلحات موضوعية: Male, Lymphoma, 040301 veterinary sciences, medicine.medical_treatment, Antineoplastic Agents, CHOP, Article, Metastasis, 0403 veterinary science, 03 medical and health sciences, Dogs, 0302 clinical medicine, Recurrence, Cancer stem cell, Cell Line, Tumor, Biomarkers, Tumor, medicine, Animals, Dog Diseases, Chemotherapy, General Veterinary, business.industry, 04 agricultural and veterinary sciences, medicine.disease, In vitro, Gene Expression Regulation, Neoplastic, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Cancer research, Female, Lymph, Stem cell, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17051acec4c3c211e6b07c8bd1f11739
https://doi.org/10.1111/vco.12447

المؤلفون: Mandana Amir Shaghaghi, Peter Eck, Brent Murphy

المصدر: Biochemistry and Cell Biology. 94:331-335

مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Genetics, Genome, Human, Alternative splicing, Glucose Transport Proteins, Facilitative, Glucose transporter, Genetic Variation, Locus (genetics), Genomics, Cell Biology, Biology, Subcellular localization, Biochemistry, Alternative Splicing, 03 medical and health sciences, Exon, 030104 developmental biology, Humans, Protein Isoforms, Tissue Distribution, Human genome, Molecular Biology, Gene, Subcellular Fractions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ddbbb42ba44a0c78904e1753cf7cef
https://doi.org/10.1139/bcb-2015-0089

المؤلفون: Brent Murphy, Wolfgang Goetzinger, Manuel Ventura

المصدر: Journal of Chromatography A. 1220:147-155

مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Diethylamines, Pyridines, Evaporation, Biochemistry, Analytical Chemistry, Ammonia, chemistry.chemical_compound, Phase (matter), Ethylamines, Organic chemistry, Diethylamine, Chromatography, Aqueous solution, Chemistry, Methanol, Organic Chemistry, Chromatography, Supercritical Fluid, Stereoisomerism, General Medicine, Silicon Dioxide, Pharmaceutical Preparations, Supercritical fluid chromatography, Amine gas treating

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dacd29e7580cff77aeda6383774f910
https://doi.org/10.1016/j.chroma.2011.11.052

المؤلفون: Marcus F, Keep, Lois, Mastrofrancesco, Daniel, Erdman, Brent, Murphy, Lynn S, Ashby

المصدر: Journal of Neurosurgery. 97:592-599

مصطلحات موضوعية: Subthalamic Nucleus, Humans, Female, Parkinson Disease, Radiosurgery, Magnetic Resonance Imaging, Aged, nervous system diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ca4a73d6bb61f687ffbf0a66f13b98
https://doi.org/10.3171/jns.2002.97.supplement_5.0592

المؤلفون: Lewis R. Groden, Brent Murphy, Judith Rodnite, Gail I. Genvert

المصدر: Cornea. 10:50-53

مصطلحات موضوعية: Ophthalmology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c8b7f04ceeae7073686acb16719e4b04
https://doi.org/10.1097/00003226-199110010-00010

المؤلفون: Emily Goers, Rozalyn Simon, Nagamani Dendukuri, Laura A. Schuresko, and Brent Murphy, R. Scott Lokey

المصدر: Journal of combinatorial chemistry. 7(5)

مصطلحات موضوعية: Sulfonamides, Membrane permeability, Microchemistry, Microfluidics, General Chemistry, Nuclear magnetic resonance spectroscopy, Dipeptides, Mass spectrometry, Aminoimidazole Carboxamide, Combinatorial chemistry, Small molecule, chemistry.chemical_compound, chemistry, Peptide Library, Polystyrenes, Polystyrene, Deconvolution, Nuclear Magnetic Resonance, Biomolecular, One bead one compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fce72645df78db9a97230823bb0968
https://pubmed.ncbi.nlm.nih.gov/16153064

المؤلفون: R Brent, Murphy

المصدر: The Southern medical record. 29(1)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::465193b15969ead1031c54805939eaed
https://pubmed.ncbi.nlm.nih.gov/36024684