المؤلفون: Horak, Peter, Uhrig, Sebastian, Witzel, Maximilian, Gil-Farina, Irene, Hutter, Barbara, Rath, Tim, Gieldon, Laura, Balasubramanian, Gnana Prakash, Pastor, Xavier, Heilig, Christoph E., Richter, Daniela, Schröck, Evelin, Ball, Claudia R., Brors, Benedikt, Braun, Christian Joerg, Albert, Michael H., Scholl, Claudia, von Kalle, Christof, Schmidt, Manfred, Fröhling, Stefan, Klein, Christoph, Glimm, Hanno

المصدر: http://lobid.org/resources/99370672770606441#!, 34(10):2785-2789.

مصطلحات موضوعية: Letter, Polymorphism, Single Nucleotide [MeSH], Humans [MeSH], Genetic Therapy/adverse effects [MeSH], Neoplasms, Second Primary/diagnosis [MeSH], Whole Exome Sequencing [MeSH], Genomics/methods [MeSH], Translational research, Genetic Testing [MeSH], Wiskott-Aldrich Syndrome/complications [MeSH], Wiskott-Aldrich Syndrome/therapy [MeSH], Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/diagnosis [MeSH], Immunophenotyping [MeSH], Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/etiology [MeSH], Genetic Therapy/methods [MeSH], Wiskott-Aldrich Syndrome/genetics [MeSH], Biomarkers, Tumor [MeSH], Gene Expression Profiling [MeSH], Second Primary/etiology [MeSH], Cancer genomics

Relation: https://repository.publisso.de/resource/frl:6471046; https://doi.org/10.1038/s41375-020-0779-z; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321895/

الاتاحة: https://repository.publisso.de/resource/frl:6471046
https://doi.org/10.1038/s41375-020-0779-z
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321895/

المؤلفون: Kauke, Monique Jacqueline, Tisdale, Alison W., Kelly, Ryan Lewis, Hemann, Michael, Wittrup, Karl Dane, Braun, Christian Joerg

المساهمون: Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Chemical Engineering, Koch Institute for Integrative Cancer Research at MIT, Kauke, Monique Jacqueline, Tisdale, Alison W., Kelly, Ryan Lewis, Braun, Christian Jorg, Hemann, Michael, Wittrup, Karl Dane

المصدر: American Association for Cancer Research

مصطلحات موضوعية: Ras, targeted therapy, competitive inhibitor, cell signaling, mathematical modeling

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1158/1535-7163.MCT-17-0645; Molecular Cancer Therapeutics; http://hdl.handle.net/1721.1/116547; Kauke, Monique J., Alison W. Tisdale, Ryan L. Kelly, Christian J. Braun, Michael T. Hemann, and K. Dane Wittrup. “A Raf-Competitive K-Ras Binder Can Fail to Functionally Antagonize Signaling.” Molecular Cancer Therapeutics (May 2, 2018):.; orcid:0000-0002-0013-3941; orcid:0000-0002-3161-2785; orcid:0000-0001-5003-9104; orcid:0000-0002-5229-8748; orcid:0000-0003-2398-5896

الاتاحة: http://hdl.handle.net/1721.1/116547

المؤلفون: Pallasch, Christian, Braun, Christian Joerg, Hemann, Michael, Pavlova, Natalya N., Elia, Andrew E. H., Westbrook, Thomas F., Elledge, Stephen J.

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Pallasch, Christian, Braun, Christian Joerg, Hemann, Michael

المصدر: PMC

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.7554/eLife.00358; eLife; http://hdl.handle.net/1721.1/84514; Pavlova, N. N., C. Pallasch, A. E. Elia, C. J. Braun, T. F. Westbrook, M. Hemann, and S. J. Elledge. “A role for PVRL4-driven cell-cell interactions in tumorigenesis.” eLife 2, no. 0 (January 8, 2013): e00358-e00358.; orcid:0000-0002-5229-8748

الاتاحة: http://hdl.handle.net/1721.1/84514

المؤلفون: Grant, Robert A., Tsao, Ming-Sound, Cannell, Ian Gordon, Merrick, Karl Andrew, Morandell, Sandra M., Grant, Robert A, Cameron, Eleanor Ruth, Hemann, Michael, Yaffe, Michael B, Braun, Christian Joerg

المساهمون: Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Cannell, Ian Gordon, Merrick, Karl Andrew, Morandell, Sandra M., Braun, Christian Jorg, Grant, Robert A, Cameron, Eleanor Ruth, Hemann, Michael, Yaffe, Michael B

المصدر: PMC

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1016/j.ccell.2015.09.009; Cancer Cell; http://hdl.handle.net/1721.1/105498; Cannell, Ian G. et al. “A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy.” Cancer Cell 28.5 (2015): 623–637.; orcid:0000-0003-4082-0292; orcid:0000-0002-5229-8748; orcid:0000-0003-0179-9216; orcid:0000-0002-9547-3251

الاتاحة: http://hdl.handle.net/1721.1/105498

المؤلفون: Sangaraju, D., Tretyakova, N., McFaline, Jose Luis, Stanciu, Monica, Nagel, Zachary D., Mazzucato, Patrizia, Cerniauskas, Edvinas, Barford, Kelly, Vargas, Amanda, Chen, Yimin, Lees, Jacqueline, Hemann, Michael, Samson, Leona D, Braun, Christian Joerg, White, Forest M.

المساهمون: Massachusetts Institute of Technology. Center for Environmental Health Sciences, Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, McFaline, Jose Luis, Braun, Christian Jorg, Stanciu, Monica, Nagel, Zachary D., Mazzucato, Patrizia, Cerniauskas, Edvinas, Barford, Kelly, Vargas, Amanda, Chen, Yimin, Lees, Jacqueline, Hemann, Michael, White, Forest M, Samson, Leona D

المصدر: PMC

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1158/0008-5472.can-14-3616; Cancer Research; http://hdl.handle.net/1721.1/106346; McFaline-Figueroa, J. L. et al. “Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide.” Cancer Research 75.15 (2015): 3127–3138.; orcid:0000-0002-5229-8748; orcid:0000-0002-7221-6041; orcid:0000-0001-9451-2194; orcid:0000-0002-1545-1651; orcid:0000-0002-7112-1454

الاتاحة: http://hdl.handle.net/1721.1/106346

المؤلفون: Braun, Christian Joerg, Witzel, Maximilian, Paruzynski, Anna, Boztug, Kaan, Kalle, Christof von, Schmidt, Manfred, Klein, Christoph

المصدر: Rare Diseases ; volume 2, issue 1, page e947749 ; ISSN 2167-5511

الاتاحة: http://dx.doi.org/10.4161/21675511.2014.947749
http://www.tandfonline.com/doi/pdf/10.4161/21675511.2014.947749

المؤلفون: Horlbeck, Max A., Gilbert, Luke A., Weissman, Jonathan S., Bruno, Peter Michael, Hemann, Michael, Braun, Christian Joerg

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Braun, Christian Jorg, Bruno, Peter Michael, Hemann, Michael

المصدر: National Academy of Sciences

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1073/PNAS.1600582113; Proceedings of the National Academy of Sciences; http://hdl.handle.net/1721.1/114928; Braun, Christian J. et al. “Versatile in Vivo Regulation of Tumor Phenotypes by dCas9-Mediated Transcriptional Perturbation.” Proceedings of the National Academy of Sciences 113, 27 (June 2016): E3892–E3900 © 2016 The Authors; orcid:0000-0002-5229-8748; orcid:0000-0003-3383-0118

الاتاحة: http://hdl.handle.net/1721.1/114928

المؤلفون: Pallasch, Christian, Leskov, Ilya B., Vorholt, Daniela, Drake, Adam, Bent, Eric H., Schwamb, Janine, Iliopoulou, Bettina P., Kutsch, Nadine, van Rooijen, Nico, Frenzel, Lukas P., Wendtner, Clemens M., Heukamp, Lukas, Kreuzer, Karl Anton, Hallek, Michael, Chen, Jianzhu, Braun, Christian Joerg, Soto Feliciano, Yadira Marie, Hemann, Michael

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Pallasch, Christian, Leskov, Ilya B., Braun, Christian Joerg, Drake, Adam, Soto Feliciano, Yadira Marie, Bent, Eric H., Iliopoulou, Bettina P., Chen, Jianzhu, Hemann, Michael

المصدر: Elsevier Open Archive

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1016/j.cell.2013.12.041; Cell; http://hdl.handle.net/1721.1/96265; Pallasch, Christian P., Ilya Leskov, Christian J. Braun, Daniela Vorholt, Adam Drake, Yadira M. Soto-Feliciano, Eric H. Bent, et al. “Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy.” Cell 156, no. 3 (January 2014): 590–602. © 2014 Elsevier Inc.; orcid:0000-0001-5118-8478; orcid:0000-0002-5229-8748; orcid:0000-0002-5687-6154; orcid:0000-0002-6604-2129

الاتاحة: http://hdl.handle.net/1721.1/96265

المؤلفون: Braun, Christian Joerg, Hemann, Michael

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Braun, Christian Joerg, Hemann, Michael

المصدر: Elsevier Open Archive

وصف الملف: application/pdf

Relation: http://dx.doi.org/10.1016/j.stem.2013.05.020; Cell Stem Cell; http://hdl.handle.net/1721.1/96413; Braun, Christian J., and Michael T. Hemann. “Unraveling Tumor Suppressor Networks with In Vivo RNAi.” Cell Stem Cell 12, no. 6 (June 2013): 639–641. © 2013 Elsevier Inc.; orcid:0000-0002-5229-8748

الاتاحة: http://hdl.handle.net/1721.1/96413

المؤلفون: Braun, Christian Jörg, Boztug, Kaan, Paruzynski, Anna, Witzel, Maximilian, Schwarzer, Adrian, Rothe, Michael, Modlich, Ute, Beier, Rita, Göhring, Gudrun, Steinemann, Doris, Fronza, Raffaele, Ball, Claudia Regina, Haemmerle, Reinhard, Naundorf, Sonja, Kühlcke, Klaus, Rose, Martina, Fraser, Chris, Mathias, Liesl, Ferrari, Rudolf, Abboud, Miguel R., Al-Herz, Waleed, Kondratenko, Irina, Maródi, László, Glimm, Hanno, Schlegelberger, Brigitte, Schambach, Axel, Albert, Michael Heinrich, Schmidt, Manfred, von Kalle, Christof, Klein, Christoph

المصدر: Science Translational Medicine ; volume 6, issue 227 ; ISSN 1946-6234 1946-6242

الاتاحة: http://dx.doi.org/10.1126/scitranslmed.3007280
https://www.science.org/doi/pdf/10.1126/scitranslmed.3007280

المؤلفون: Witzel, Maximilian Georg Wolfgang, Braun, Christian Joerg, Boztug, Kaan, Klein, Christoph

المصدر: Expert Opinion on Orphan Drugs ; volume 1, issue 9, page 705-715 ; ISSN 2167-8707

الاتاحة: http://dx.doi.org/10.1517/21678707.2013.830068
https://www.tandfonline.com/doi/pdf/10.1517/21678707.2013.830068