المؤلفون: Caria, Inês, Nunes, Maria João, Ciraci, Viviana, Carvalho, Andreia Neves, Ranito, Catarina, Santos, Susana G., Gama, Maria João, Castro-Caldas, Margarida, Rodrigues, Cecília M. P., Ruas, Jorge L., Rodrigues, Elsa

المساهمون: DCV - Departamento de Ciências da Vida, UCIBIO - Applied Molecular Biosciences Unit

مصطلحات موضوعية: Brain cholesterol metabolism, Lysosomes, Mitochondria dysfunction, NPC1, Parkinson's disease, Molecular Medicine, Molecular Biology, SDG 3 - Good Health and Well-being

Relation: PURE: 81715012; PURE UUID: 6c90fd4d-1349-442e-8cf8-eaac0124a925; Scopus: 85179468022; WOS: 001139877100001; PubMed: 38061599; http://hdl.handle.net/10362/163059; https://doi.org/10.1016/j.bbadis.2023.166980

الاتاحة: http://hdl.handle.net/10362/163059
https://doi.org/10.1016/j.bbadis.2023.166980

المؤلفون: Nunes, Maria João, Carvalho, Andreia Neves, Reis, Joana, Costa, Daniela, Moutinho, Miguel, Mateus, Joana, Mendes de Almeida, Rita, Brito, Sara, Risso, Daniela, Nunes, Sofia, Castro-Caldas, Margarida, Gama, Maria João, Rodrigues, Cecília M. P., Xapelli, Sara, Diógenes, Maria José, Cartier, Nathalie, Chali, Farah, Piguet, Françoise, Rodrigues, Elsa

المساهمون: DCV - Departamento de Ciências da Vida

مصطلحات موضوعية: Brain cholesterol metabolism, CYP46A1, Gene therapy, Neurodegeneration, Niemann-Pick type C disorders, Molecular Medicine, Molecular Biology, SDG 3 - Good Health and Well-being

Relation: PURE: 81714682; PURE UUID: 76ed1a53-bb74-406b-adf9-72b0105fd2c4; Scopus: 85181842546; WOS: 001153521200001; PubMed: 38142760; http://hdl.handle.net/10362/167730; https://doi.org/10.1016/j.bbadis.2023.166993

الاتاحة: http://hdl.handle.net/10362/167730
https://doi.org/10.1016/j.bbadis.2023.166993

المؤلفون: Reis, Joana Pinheiro Leite da Anunciação

المساهمون: Nunes, Maria João de Jesus, Rodrigues, Elsa Margarida Teixeira, Repositório da Universidade de Lisboa

مصطلحات موضوعية: Niemann-Pick Type C disease (NPC), Cholesterol 24-hydroxylase (CYP46A1), Brain cholesterol metabolism, Neuroinflammation, Autophagy, Teses de mestrado - 2022, Ciências da Saúde

وصف الملف: application/pdf

الاتاحة: http://hdl.handle.net/10451/62941

المؤلفون: Paola Gamba, Serena Giannelli, Erica Staurenghi, Gabriella Testa, Barbara Sottero, Fiorella Biasi, Giuseppe Poli, Gabriella Leonarduzzi

المساهمون: Paola Gamba, Serena Giannelli, Erica Staurenghi, Gabriella Testa, Barbara Sottero, Fiorella Biasi, Giuseppe Poli, Gabriella Leonarduzzi

مصطلحات موضوعية: 24-S-hydroxycholesterol, Alzheimer’s disease, CYP46A1, brain cholesterol metabolism, cerebrosterol, neurodegeneration, neuroprotection, oxysterol, statins

Relation: info:eu-repo/semantics/altIdentifier/pmid/34067119; info:eu-repo/semantics/altIdentifier/wos/WOS:000653343200001; volume:10; firstpage:740; lastpage:758; numberofpages:19; journal:ANTIOXIDANTS; http://hdl.handle.net/2318/1792597; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85105367230

الاتاحة: http://hdl.handle.net/2318/1792597

المؤلفون: Michelle Flores Domingues, Natalia Callai-Silva, Angela Regina Piovesan, Celia Regina Carlini

المصدر: Frontiers in Molecular Neuroscience, Vol 12 (2020)

مصطلحات موضوعية: soluble epoxide hydrolase, N-terminal domain, phosphatase activity, brain cholesterol metabolism, Alzheimer’s disease, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnmol.2019.00325/full; https://doaj.org/toc/1662-5099

URL الوصول: https://doaj.org/article/0e8363aa65394b1abc5fc26b225a4559

المؤلفون: Ferris, Heather A., Perry, Rachel J., Moreira, Gabriela V., Shulman, Gerald I., Horton, Jay D., Kahn, C. Ronald

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2017 Jan . 114(5), 1189-1194.

URL الوصول: https://www.jstor.org/stable/26479157

المؤلفون: Ahmed A. Saeed, Erik Edström, Irina Pikuleva, Gösta Eggertsen, Ingemar Björkhem

المصدر: Journal of Lipid Research, Vol 58, Iss 2, Pp 455-459 (2017)

مصطلحات موضوعية: steroid acid, blood-brain barrier, subdural hematoma, subarachnoidal bleeding, brain cholesterol metabolism, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520314267; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/b9a3f79858e14db88ea92533aa574d91

المؤلفون: Joanna M. Karasinska, Willeke de Haan, Sonia Franciosi, Piers Ruddle, Jianjia Fan, Janine K. Kruit, Sophie Stukas, Dieter Lütjohann, David H. Gutmann, Cheryl L. Wellington, Michael R. Hayden

المصدر: Neurobiology of Disease, Vol 54, Iss , Pp 445-455 (2013)

مصطلحات موضوعية: Brain cholesterol metabolism, ABCA1, Apolipoproteins, Neuroinflammation, Neurodegeneration, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996113000429; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/3dc3c252ec2147fcbb40237917fdac8e

المؤلفون: Maria João Nunes, Miguel Moutinho, Inês Milagre, Maria João Gama, Elsa Rodrigues

المصدر: Journal of Lipid Research, Vol 53, Iss 9, Pp 1910-1919 (2012)

مصطلحات موضوعية: gene regulation, cytochrome P450, brain cholesterol metabolism, SP transcription factors, HDAC inhibitors, MAPK signaling pathway and protein phosphatase inhibition, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520418334; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/654dece0d74146a5ac2f0d72e8af744b

المؤلفون: Dieter Lütjohann, Andreas Brzezinka, Esther Barth, Dorothee Abramowski, Matthias Staufenbiel, Klaus von Bergmann, Konrad Beyreuther, Gerd Multhaup, Thomas A. Bayer

المصدر: Journal of Lipid Research, Vol 43, Iss 7, Pp 1078-1085 (2002)

مصطلحات موضوعية: Alzheimer disease, brain cholesterol metabolism, neurodegeneration, oxysterols, plant sterols, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S002222752031470X; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/a4e0bffcac134473b2790d13b6d0fde3

المؤلفون: Barbara Sottero, Fiorella Biasi, Paola Gamba, Erica Staurenghi, Gabriella Leonarduzzi, Gabriella Testa, Giuseppe Poli, Serena Giannelli

المصدر: Antioxidants, Vol 10, Iss 740, p 740 (2021)
Antioxidants

مصطلحات موضوعية: 0301 basic medicine, cerebrosterol, Oxysterol, Physiology, Clinical Biochemistry, Review, Disease, RM1-950, medicine.disease_cause, Biochemistry, Neuroprotection, statins, Pathogenesis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, 24-S-hydroxycholesterol, medicine, Molecular Biology, Neuroinflammation, brain cholesterol metabolism, business.industry, Cholesterol, Neurodegeneration, neurodegeneration, Cell Biology, Alzheimer’s disease, CYP46A1, neuroprotection, oxysterol, medicine.disease, 030104 developmental biology, chemistry, lipids (amino acids, peptides, and proteins), Therapeutics. Pharmacology, business, Neuroscience, 030217 neurology & neurosurgery, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2cdc4156497213fa25decb046c6698
https://www.mdpi.com/2076-3921/10/5/740

المؤلفون: Jahn, T., Clark, C., Kerksiek, A., Lewczuk, P., Lütjohann, D., Popp, J.

المصدر: The Journal of steroid biochemistry and molecular biology, vol. 205, pp. 105785

مصطلحات موضوعية: Alzheimer’s disease, brain cholesterol metabolism, cerebrospinal fluid, cholesterol synthesis, lipids, neurodegeneration, oxysterols

Relation: info:eu-repo/semantics/altIdentifier/pmid/33171206; info:eu-repo/semantics/altIdentifier/eissn/1879-1220; https://serval.unil.ch/notice/serval:BIB_7CB2F980F7D1

الاتاحة: https://serval.unil.ch/notice/serval:BIB_7CB2F980F7D1
https://doi.org/10.1016/j.jsbmb.2020.105785

المؤلفون: Reis, Joana Pinheiro Leite da Anunciação

المساهمون: Nunes, Maria João de Jesus, Rodrigues, Elsa Margarida Teixeira

مصطلحات موضوعية: Niemann-Pick Type C disease (NPC), Cholesterol 24-hydroxylase (CYP46A1), Brain cholesterol metabolism, Neuroinflammation, Autophagy, Teses de mestrado - 2022, Ciências da Saúde

Relation: info:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FMED-NEU%2F29455%2F2017/PT; http://hdl.handle.net/10451/62941; 203198689

الاتاحة: http://hdl.handle.net/10451/62941

المؤلفون: Mehak Agarwal, Safeera Khan

المصدر: Cureus

مصطلحات موضوعية: Apolipoprotein E, medicine.medical_specialty, plasma lipid biomarkers, Apolipoprotein B, 030204 cardiovascular system & hematology, Presenilin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, PSEN2, PSEN1, medicine, Internal Medicine, Dementia, alzheimers disease, cognitive impairment, brain cholesterol metabolism, Psychiatry, biology, Cholesterol, business.industry, General Engineering, cholesterol, medicine.disease, Endocrinology, chemistry, Neurology, ABCA1, biology.protein, lipids (amino acids, peptides, and proteins), business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b54298d58bc834d42f0ed24cd05f49
https://pubmed.ncbi.nlm.nih.gov/33457117

المؤلفون: Folkert Kuipers, Leonie C. van Vark-van der Zee, Eric J.G. Sijbrands, Tim Vanmierlo, Kris Rutten, Vincent W. Bloks, Dieter Luetjohann, Harry W.M. Steinbusch, Monique T. Mulder, Anja Kerksiek, Silvia Friedrichs

المساهمون: Center for Liver, Digestive and Metabolic Diseases (CLDM), Psychiatrie & Neuropsychologie, RS: MHeNs School for Mental Health and Neuroscience, Internal Medicine

المصدر: Journal of alzheimers disease, 19(1), 117-127. IOS Press
Journal of Alzheimer's Disease, 19(1), 117-127. IOS Press
Journal of Alzheimers Disease, 19(1), 117-127. IOS Press BV

مصطلحات موضوعية: GAMMA-SECRETASE, Hippocampus, A-BETA GENERATION, seladin, ACTIVATION, Amyloid beta-Protein Precursor, Mice, chemistry.chemical_compound, 0302 clinical medicine, Desmosterol, Amyloid precursor protein, NEURONS, APPSLxPS1mut, brain cholesterol metabolism, TRANSGENIC MICE, 0303 health sciences, biology, General Neuroscience, Age Factors, Brain, General Medicine, Alzheimer's disease, AMYLOID PRECURSOR PROTEIN, Psychiatry and Mental health, Clinical Psychology, Cholesterol, 24S-HYDROXYCHOLESTEROL, oxysterols, LXR, lipids (amino acids, peptides, and proteins), Oxidoreductases Acting on CH-CH Group Donors, medicine.medical_specialty, Mice, Transgenic, Nerve Tissue Proteins, Presenilin, Mice, Neurologic Mutants, 03 medical and health sciences, CEREBROSPINAL-FLUID, Alzheimer Disease, Internal medicine, Presenilin-1, medicine, Animals, Liver X receptor, 030304 developmental biology, medicine.disease, GENE, Mice, Inbred C57BL, Disease Models, Animal, Endocrinology, chemistry, ABCA1, biology.protein, Geriatrics and Gerontology, LIVER-X-RECEPTOR, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc9a4d8aaf1710f320cb834d537efa3
https://doi.org/10.3233/jad-2010-1209

المؤلفون: Smiljanic, Kosara, VANMIERLO, Tim, Djordjevic, Aleksandra Mladenovic, Perovic, Milka, Ivkovic, Sanja, Luetjohann, Dieter, Kanazir, Selma

مصطلحات موضوعية: Dietary restriction, Brain cholesterol metabolism, 24S-hydroxycholesterol, Phytosterols, Rat cortex, Hippocampus

وصف الملف: application/pdf

Relation: AGE, 36 (3), p. 1303-1314; http://hdl.handle.net/1942/17689; 1314; 1303; 36; 000342142300022

الاتاحة: http://hdl.handle.net/1942/17689
https://doi.org/10.1007/s11357-014-9654-z

المؤلفون: Vanmierlo, Tim, Bloks, Vincent W., van Vark-van der Zee, Leonie C., Rutten, Kris, Kerksiek, Anja, Friedrichs, Silvia, Sijbrands, Eric J. G., Steinbusch, Harry W., Kuipers, Folkert, Luetjohann, Dieter, Mulder, Monique

المصدر: Vanmierlo , T , Bloks , V W , van Vark-van der Zee , L C , Rutten , K , Kerksiek , A , Friedrichs , S , Sijbrands , E J G , Steinbusch , H W , Kuipers , F , Luetjohann , D & Mulder , M 2010 , ' Alterations in Brain Cholesterol Metabolism in the APPSLxPS1mut mouse, a Model for Alzheimer's Disease ' , Journal of Alzheimer's Disease , vol. 19 , no. 1 , pp. 117-127 . https://doi.org/10.3233/JAD-2010-1209

مصطلحات موضوعية: APPSLxPS1mut, Alzheimer's disease, brain cholesterol metabolism, LXR, oxysterols, seladin

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/1f9beaf3-f7f1-4868-8ee4-61b70795ceb5
https://doi.org/10.3233/JAD-2010-1209

المؤلفون: Miguel Moutinho, Maria João Nunes, Elsa Rodrigues, Inês Milagre, Maria João Gama

المصدر: Journal of Lipid Research, Vol 53, Iss 9, Pp 1910-1919 (2012)

مصطلحات موضوعية: Time Factors, Transcription, Genetic, cytochrome P450, MAP Kinase Kinase 1, QD415-436, Biology, Hydroxamic Acids, MAPK signaling pathway and protein phosphatase inhibition, Biochemistry, Gene Expression Regulation, Enzymologic, chemistry.chemical_compound, Endocrinology, Sp3 transcription factor, SP transcription factors, HDAC inhibitors, Cell Line, Tumor, Okadaic Acid, medicine, Cholesterol 24-Hydroxylase, Homeostasis, Humans, Phosphorylation, Promoter Regions, Genetic, Research Articles, brain cholesterol metabolism, Regulation of gene expression, Mitogen-Activated Protein Kinase 1, Neurons, Mitogen-Activated Protein Kinase 3, Kinase, Brain, Cell Biology, Okadaic acid, Phosphoproteins, Molecular biology, Trichostatin A, Cholesterol, Sp3 Transcription Factor, chemistry, Organ Specificity, Enzyme Induction, Steroid Hydroxylases, Histone deacetylase, Signal transduction, gene regulation, Chromatin immunoprecipitation, medicine.drug, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62efeb76deb250f8dd3fb616dd96e228
https://pubmed.ncbi.nlm.nih.gov/22693257