نتائج البحث - "Braggio, Simone"

1

Book

Discovery Toxicology in Lead Optimization

المؤلفون: Fontana, Stefano, Braggio, Simone, Corsi, Mauro, Riley, Rob, Strock, Chris, Bradley, Jenifer, Virginio, Caterina, Walker, Paul

المصدر: The Handbook of Medicinal Chemistry ; page 533-596 ; ISBN 9781788018982 9781788018982 9781839165887 9781837671076

الاتاحة: http://dx.doi.org/10.1039/9781788018982-00533
https://books.rsc.org/books/edited-volume/chapter-pdf/1494983/bk9781788018982-00533.pdf

View record in BASE

2

Academic Journal

1,2,4-Triazolyl 5-Azaspiro[2.4]heptanes: Lead Identification and Early Lead Optimization of a New Series of Potent and Selective Dopamine D3 Receptor Antagonists

المساهمون: Micheli, Fabrizio, Bacchi, Alessia, Braggio, Simone, Castelletti, Laura, Cavallini, Palmina, Cavanni, Paolo, Cremonesi, Susanna, Dal Cin, Michele, Feriani, Aldo, Gehanne, Sylvie, Kajbaf, Mahmud, Marchio', Luciano, Nola, Selena, Oliosi, Beatrice, Pellacani, Annalisa, Perdonà, Elisabetta, Sava, Anna, Semeraro, Teresa, Tarsi, Luca, Tomelleri, Silvia, Wong, Andrea, Visentini, Filippo, Zonzini, Laura, Heidbreder, Christian

مصطلحات موضوعية: Molecular Medicine, Drug Discovery3003 Pharmaceutical Science

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000384035300025; volume:59; issue:18; firstpage:8549; lastpage:8576; numberofpages:28; journal:JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11381/2817890; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84988719550

الاتاحة: http://hdl.handle.net/11381/2817890
https://doi.org/10.1021/acs.jmedchem.6b00972
http://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.6b00972

View record in BASE

3

Academic Journal

New fused benzazepine as selective D3 receptor antagonists. Synthesis and biological evaluation. Part 2: [g]-Fused and hetero-fused systems

المؤلفون: Micheli, Fabrizio, Bonanomi, Giorgio, Braggio, Simone, Capelli, Anna Maria, Damiani, Federica, Di Fabio, Romano, Donati, Daniele, Gentile, Gabriella, Hamprecht, Dieter, Perini, Ornella, Petrone, Marcella, Tedesco, Giovanna, Terreni, Silvia, Worby, Angela, Heidbreder, Christian

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 18, issue 3, page 908-912 ; ISSN 0960-894X

الاتاحة: https://doi.org/10.1016/j.bmcl.2007.12.042
https://api.elsevier.com/content/article/PII:S0960894X07015004?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X07015004?httpAccept=text/plain

View record in BASE

4

Academic Journal

New fused benzazepine as selective D3 receptor antagonists. Synthesis and biological evaluation. Part one: [h]-fused tricyclic systems

المؤلفون: Micheli, Fabrizio, Bonanomi, Giorgio, Braggio, Simone, Capelli, Anna Maria, Celestini, Paolo, Damiani, Federica, Fabio, Romano Di, Donati, Daniele, Gagliardi, Stefania, Gentile, Gabriella, Hamprecht, Dieter, Petrone, Marcella, Radaelli, Stefano, Tedesco, Giovanna, Terreni, Silvia, Worby, Angela, Heidbreder, Christian

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 18, issue 3, page 901-907 ; ISSN 0960-894X

الاتاحة: https://doi.org/10.1016/j.bmcl.2007.12.066
https://api.elsevier.com/content/article/PII:S0960894X07015016?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X07015016?httpAccept=text/plain

View record in BASE

5

Academic Journal

1,2,4-Triazol-3-yl-thiopropyl-tetrahydrobenzazepines: A Series of Potent and Selective Dopamine D 3 Receptor Antagonists

المصدر: Journal of Medicinal Chemistry ; volume 50, issue 21, page 5076-5089 ; ISSN 0022-2623 1520-4804

الاتاحة: https://doi.org/10.1021/jm0705612
https://pubs.acs.org/doi/pdf/10.1021/jm0705612

View record in BASE

6

Academic Journal

In Vitro and In Vivo Pharmacokinetics-Pharmacodynamics of GV143253A, a Novel Trinem

المؤلفون: Ferrari, Livia, Iavarone, Laura, Braggio, Simone, Di Modugno, Enza

المصدر: Antimicrobial Agents and Chemotherapy ; volume 47, issue 2, page 770-776 ; ISSN 0066-4804 1098-6596

الاتاحة: http://dx.doi.org/10.1128/aac.47.2.770-776.2003
https://journals.asm.org/doi/pdf/10.1128/AAC.47.2.770-776.2003

View record in BASE

7

Book

CHAPTER 15. Discovery Toxicology In Lead Optimisation

المؤلفون: Braggio, Simone, Corsi, Mauro, Feriani, Aldo, Fontana, Stefano, Marocchio, Luciana, Virginio, Caterina

المصدر: The Handbook of Medicinal Chemistry ; page 364-412 ; ISBN 9781849736251

الاتاحة: http://dx.doi.org/10.1039/9781782621836-00364

View record in BASE

8

Academic Journal

1,2,4-Triazolyl octahydropyrrolo[2,3-b]pyrroles: A new series of potent and selective dopamine D3 receptor antagonists

المؤلفون: Micheli, Fabrizio, Bernardelli, Andrea, Bianchi, Federica, Braggio, Simone, Castelletti, Laura, Cavallini, Palmina, Cavanni, Paolo, Cremonesi, Susanna, Cin, Michele Dal, Feriani, Aldo, Oliosi, Beatrice, Semeraro, Teresa, Tarsi, Luca, Tomelleri, Silvia, Wong, Andrea, Visentini, Filippo, Zonzini, Laura, Heidbreder, Christian

المصدر: Bioorganic & Medicinal Chemistry ; volume 24, issue 8, page 1619-1636 ; ISSN 0968-0896

الاتاحة: http://dx.doi.org/10.1016/j.bmc.2016.02.031
https://api.elsevier.com/content/article/PII:S0968089616301225?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0968089616301225?httpAccept=text/plain

View record in BASE

9

Academic Journal

Novel morpholine scaffolds as selective dopamine (DA) D3 receptor antagonists

المؤلفون: Micheli, Fabrizio, Cremonesi, Susanna, Semeraro, Teresa, Tarsi, Luca, Tomelleri, Silvia, Cavanni, Paolo, Oliosi, Beatrice, Perdonà, Elisabetta, Sava, Anna, Zonzini, Laura, Feriani, Aldo, Braggio, Simone, Heidbreder, Christian

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 26, issue 4, page 1329-1332 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2015.12.081
https://api.elsevier.com/content/article/PII:S0960894X15303954?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0960894X15303954?httpAccept=text/xml

View record in BASE

10

Academic Journal

Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate

المؤلفون: Di Fabio, Romano, Alvaro, Giuseppe, Braggio, Simone, Carletti, Renzo, Gerrard, Philip A., Griffante, Cristiana, Marchioro, Carla, Pozzan, Alfonso, Melotto, Sergio, Poffe, Alessandro, Piccoli, Laura, Ratti, Emiliangelo, Tranquillini, Elvira, Trower, Michael, Spada, Simone, Corsi, Mauro

المصدر: Bioorganic & Medicinal Chemistry ; volume 21, issue 21, page 6264-6273 ; ISSN 0968-0896

الاتاحة: http://dx.doi.org/10.1016/j.bmc.2013.09.001
https://api.elsevier.com/content/article/PII:S0968089613007724?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0968089613007724?httpAccept=text/plain

View record in BASE

11

Academic Journal

Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 21, issue 18, page 5562-5567 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2011.06.086
https://api.elsevier.com/content/article/PII:S0960894X11008699?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X11008699?httpAccept=text/plain

View record in BASE

12

Academic Journal

Quality by Design in lead optimization: a new strategy to address productivity in drug discovery

المؤلفون: Rossi, Tino, Braggio, Simone

المصدر: Current Opinion in Pharmacology ; volume 11, issue 5, page 515-520 ; ISSN 1471-4892

الاتاحة: http://dx.doi.org/10.1016/j.coph.2011.05.004
https://api.elsevier.com/content/article/PII:S1471489211000695?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1471489211000695?httpAccept=text/plain

View record in BASE

13

Academic Journal

1-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes:a new series of potent and selective triple reuptake inhibitors

المصدر: Micheli , F , Cavanni , P , Arban , R , Benedetti , R , Bertani , B , Bettati , M , Bettelini , L , Bonanomi , G , Braggio , S , Checchia , A , Davalli , S , Di Fabio , R , Fazzolari , E , Fontana , S , Marchioro , C , Minick , D , Negri , M , Oliosi , B , Read , K D , Sartori , I , Tedesco , G , Tarsi , L , Terreni , S , Visentini , F , Zocchi ....

الاتاحة: https://discovery.dundee.ac.uk/en/publications/4cc02521-7380-499b-a0fe-d43e8ef06eb7
https://doi.org/10.1021/jm901818u

View record in BASE

14

Academic Journal

6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane:a new potent and selective triple reuptake inhibitor

المصدر: Micheli , F , Cavanni , P , Andreotti , D , Arban , R , Benedetti , R , Bertani , B , Bettati , M , Bettelini , L , Bonanomi , G , Braggio , S , Carletti , R , Checchia , A , Corsi , M , Fazzolari , E , Fontana , S , Marchioro , C , Merlo-Pich , E , Negri , M , Oliosi , B , Ratti , E , Read , K D , Roscic , M , Sartori , I , Spada , S , Tedesco , ....

Relation: https://discovery.dundee.ac.uk/en/publications/b1476fe9-1d2f-4ec4-a1d0-c14b60720aae

الاتاحة: https://discovery.dundee.ac.uk/en/publications/b1476fe9-1d2f-4ec4-a1d0-c14b60720aae
https://doi.org/10.1021/jm100481d

View record in BASE

15

Academic Journal

Assessing brain free fraction in early drug discovery

المؤلفون: Read, Kevin D., Braggio, Simone

المصدر: Read , K D & Braggio , S 2010 , ' Assessing brain free fraction in early drug discovery ' , Expert Opinion on Drug Metabolism and Toxicology , vol. 6 , no. 3 , pp. 337-344 . https://doi.org/10.1517/17425250903559873

Relation: https://discovery.dundee.ac.uk/en/publications/1a1243f5-8b22-47b9-a554-ff6e4704a555

الاتاحة: https://discovery.dundee.ac.uk/en/publications/1a1243f5-8b22-47b9-a554-ff6e4704a555
https://doi.org/10.1517/17425250903559873

View record in BASE