المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899920

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s001

المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/dataset/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899923

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s002

المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/dataset/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899926

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s003

المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/dataset/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899929

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s004

المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/dataset/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899932

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s005

المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/dataset/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899935

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s006