المؤلفون: Venkatesan, S, Angelova, M, Puttick, C, Zhai, HR, Caswell, DR, Lu, WT, Dietzen, M, Galanos, P, Evangelou, K, Bellelli, R, Lim, EL, Watkins, TBK, Rowan, A, Teixeira, VH, Zhao, Y, Chen, HQ, Ngo, B, Zalmas, LP, Al Bakir, M, Hobor, S, Gronroos, E, Pennycuick, A, Nigro, E, Campbell, BB, Brown, WL, Akarca, AU, Marafioti, T, Wu, MY, Howell, M, Boulton, SJ, Bertoli, C, Fenton, TR, de Bruin, RAM, Maya-Mendoza, A, Santoni-Rugiu, E, Hynds, RE, Gorgoulis, VG, Jamal-Hanjani, M, McGranahan, N, Harris, RS, Janes, SM, Bartkova, J, Bakhoum, SF, Bartek, J, Kanu, N, Swanton, C

المصدر: Cancer discovery. 11(10):2456-2473

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:147835123

المؤلفون: Aktas, Y, So, E, Johnson, C, Donmez, K, Ozden, AT, Parammal Vatteri, A, O'Kane, A, Kalkan, A, Andonov, A, Verrucci, E, Cabuk, E, Opabola, E, Malcioglu, FS, Markov, HP, Giardina, G, Madabushi, G, Triantafyllou, I, Byun, J-E, Nathan, J, Asinari, M, Free, M, Bashein, M, Bektas, N, Adamidis, O, Gozenoglu, O, Milillo, P, Dede, S, Boulton, SJ, Acikgoz, S, Gokce, T, Efeoglu, T, Tetik, T, Novelli, V, Gonnuru, P, Voelker, B, Tavakkoli, A, Macchiarulo, V, Gutierrez-Urzua, F, Freddi, F, Rossetto, T

المصدر: EEFIT: London, UK.

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10186995/1/2023TurkiyeEQ_EEFIT_Report_f.pdf; https://discovery.ucl.ac.uk/id/eprint/10186995/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10186995/1/2023TurkiyeEQ_EEFIT_Report_f.pdf
https://discovery.ucl.ac.uk/id/eprint/10186995/

المؤلفون: Aktas, Y, Donmez, K, So, E, Johnson, C, Ozden, AT, Parammal Vatteri, A, O'Kane, A, Kalkan, A, Andonov, A, Verrucci, E, Cabuk, E, Opabola, E, Malcioglu, FS, Marko, HP, Giardina, G, Madabushi, G, Triantafyllou, I, Byun, J-E, Jones, JN, Asinari, M, Free, M, Bashein, M, Bektas, N, Adamidis, O, Gozenoglu, O, Milillo, P, Dede, S, Boulton, SJ, Acikgoz, S, Gokce, T, Efeoglu, T, Tetik, T, Novelli, V

المصدر: EEFIT: London, UK.

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10186996/1/Aktas_EEFIT-Turkiye_EQ_2023-TurkceGenisletilmisOzet%20%281%29.pdf; https://discovery.ucl.ac.uk/id/eprint/10186996/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10186996/1/Aktas_EEFIT-Turkiye_EQ_2023-TurkceGenisletilmisOzet%20%281%29.pdf
https://discovery.ucl.ac.uk/id/eprint/10186996/

المؤلفون: Schimmel, Joost, Muñoz-Subirana, Núria, Kool, H, van Schendel, Robin, van der Vlies, Sven, Kamp, Juliette, de Vrij, Femke, Kushner, Steven, Smith, Graeme C.M., Boulton, SJ, Tijsterman, Marcel

المصدر: Schimmel , J , Muñoz-Subirana , N , Kool , H , van Schendel , R , van der Vlies , S , Kamp , J , de Vrij , F , Kushner , S , Smith , G C M , Boulton , SJ & Tijsterman , M 2023 , ' Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways ' , Cell Reports , vol. 42 , no. 2 , 112019 . https://doi.org/10.1016/j.celrep.2023.112019

وصف الملف: application/pdf

الاتاحة: https://pure.eur.nl/en/publications/13c5895e-25ca-427c-826b-f13719a0c5e2
https://doi.org/10.1016/j.celrep.2023.112019
https://pure.eur.nl/ws/files/81366710/Modulating_mutational_outcomes_and_improving_precise_gene_editing_at_CRISPR_Cas9_induced_breaks_by_chemical_inhibition_of_end_joining_pathways.pdf
http://www.scopus.com/inward/record.url?scp=85146842806&partnerID=8YFLogxK

المؤلفون: Belan, O, Greenhough, L, Kuhlen, L, Anand, R, Kaczmarczyk, A, Gruszka, DT, Yardimci, H, Zhang, X, Rueda, DS, West, SC, Boulton, SJ

Relation: https://ora.ox.ac.uk/objects/uuid:bc04db79-b22e-4eb5-a958-cef2ed2d23ed; https://doi.org/10.1016/j.molcel.2023.06.031

الاتاحة: https://doi.org/10.1016/j.molcel.2023.06.031
https://ora.ox.ac.uk/objects/uuid:bc04db79-b22e-4eb5-a958-cef2ed2d23ed

المؤلفون: Rodriguez-Berriguete, G, Ranzani, M, Prevo, R, Puliyadi, R, Machado, N, Bolland, HR, Millar, V, Ebner, D, Boursier, M, Cerutti, A, Cicconi, A, Galbiati, A, Grande, D, Grinkevich, V, Majithiya, J, Piscitello, D, Rajendra, E, Stockley, M, Boulton, SJ, Heald, R, Hammond, EM, Smith, GCM, Robinson, H, Higgins, GS

Relation: https://ora.ox.ac.uk/objects/uuid:82663df8-f5e9-4433-80bd-20a96271b182; https://doi.org/10.1158/1078-0432.ccr-22-2977

الاتاحة: https://doi.org/10.1158/1078-0432.ccr-22-2977
https://ora.ox.ac.uk/objects/uuid:82663df8-f5e9-4433-80bd-20a96271b182

المؤلفون: Newton, MD, Losito, M, Smith, QM, Parnandi, N, Taylor, BJ, Akcakaya, P, Maresca, M, van Eijk, P, Reed, SH, Boulton, SJ, King, GA, Cuomo, ME, Rueda, DS

المصدر: Molecular Cell , 83 (19) 3533-3545.e5. (2023)

مصطلحات موضوعية: CRISPR/Cas9, Gene editing, DNA topology, Genome-wide off-target, Single-molecule microscopy, Optical-tweezers, Negative supercoiling, Next Generation Sequencing, Cell editing, Transcription-coupled off-targets

وصف الملف: application/pdf

Relation: https://discovery.ucl.ac.uk/id/eprint/10178647/1/King_Negative%20DNA%20supercoiling%20induces%20genome-wide%20Cas9%20off-target%20activity_VoR.pdf; https://discovery.ucl.ac.uk/id/eprint/10178647/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10178647/1/King_Negative%20DNA%20supercoiling%20induces%20genome-wide%20Cas9%20off-target%20activity_VoR.pdf
https://discovery.ucl.ac.uk/id/eprint/10178647/

المؤلفون: Zatreanu, DA, Robinson, HMR, Alkhatib, O, Boursier, M, Finch, H, Geo, L, Grande, D, Grinkevich, V, Heald, R, Langdon, S, Majithiya, J, McWhirter, C, Martin, NMB, Moore, S, Neves, J, Rajendra, E, Ranzani, M, Schaedler, T, Stockley, M, Wiggins, K, Brough, R, Sridhar, S, Gulati, A, Shao, N, Badder, LM, Novo, D, Knight, EG, Marlow, R, Haider, S, Callen, E, Hewitt, G, Schimmel, J, Prevo, R, Alli, C, Ferdinand, A, Bell, C, Blencowe, P, Calder, M, Charles, M, Curry, J, Ekwuru, T, Ewings, K, Nussenzweig, A, Tijsterman, M, Tutt, A, Boulton, SJ, Higgins, GS, Pettitt, S, Smith, GCM, Lord, CJ

المساهمون: Haider, Syed

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Oncology

وصف الملف: ? (3); application/pdf

Relation: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000776028100106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4b848928d1c3e5c86d298abb68475f9; MOLECULAR CANCER THERAPEUTICS, 2021, 20 (12), pp. ? - ? (3); https://repository.icr.ac.uk/handle/internal/5106

الاتاحة: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000776028100106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4b848928d1c3e5c86d298abb68475f9
https://repository.icr.ac.uk/handle/internal/5106
https://doi.org/10.1158/1535-7163.TARG-21-P056

المؤلفون: Aktas, Yasemin, So, E, Johnson, C, Cabuk, E, Malcioglu, FS, Donmez, K, Asinari, M, Adamidis, O, Milillo, P, Tetik, T, Novelli, V, Parammal Vatteri, A, O'Kane, A, Kalkan, A, Ozden, AT, Andonov, A, Verrucci, E, Opabola, E, Markov, HP, Giardina, G, Madabhushi, G, Triantafyllou, I, Byun, J-E, Jones, JN, Free, M, Bektas, N, Gozenoglu, O, Dede, S, Boulton, SJ, Acikgoz, S, Gokce, T, Efeoglu, T

المصدر: In: Proceedings of the SECED 2023 Conference Earthquake Engineering & Dynamics for a Sustainable Future. Society for Earthquake and Civil Engineering Dynamics (SECED): Cambridge, UK. (2023)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10179056/1/seced_f_rev2.pdf; https://discovery.ucl.ac.uk/id/eprint/10179056/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10179056/1/seced_f_rev2.pdf
https://discovery.ucl.ac.uk/id/eprint/10179056/

المؤلفون: Zondervan, J, Stokes, M, Boulton, SJ, Telfer, MW, Mather, AE

وصف الملف: application/octet-stream

Relation: https://pearl.plymouth.ac.uk/handle/10026.1/22480

الاتاحة: https://pearl.plymouth.ac.uk/handle/10026.1/22480
https://doi.org/10.1130/abs/2022pr-376063

المؤلفون: Silva, N, Castellano-Pozo, M, Matsuzaki, K, Barroso, C, Roman-Trufero, M, Craig, H, Brooks, DR, Isaac, RE, Boulton, SJ, Martinez-Perez, E

وصف الملف: application/pdf

Relation: http://usir.salford.ac.uk/id/eprint/63107/1/pgen.1010025.pdf; Silva, N orcid:0000-0001-5406-2280 , Castellano-Pozo, M orcid:0000-0003-4134-9025 , Matsuzaki, K, Barroso, C orcid:0000-0002-0661-3460 , Roman-Trufero, M, Craig, H orcid:0000-0003-0405-5300 , Brooks, DR orcid:0000-0001-7123-5649 , Isaac, RE orcid:0000-0003-4792-6559 , Boulton, SJ orcid:0000-0001-6936-6834 and Martinez-Perez, E orcid:0000-0001-5813-0383 2022, 'Proline-specific aminopeptidase P prevents replication-associated genome instability' , PLOS Genetics, 18 (1) , e1010025.

الاتاحة: http://usir.salford.ac.uk/id/eprint/63107/
http://usir.salford.ac.uk/id/eprint/63107/1/pgen.1010025.pdf
https://doi.org/10.1371/journal.pgen.1010025

المؤلفون: Kaczmarczyk, AP, Déclais, A-C, Newton, MD, Boulton, SJ, Lilley, DMJ, Rueda, DS

المساهمون: Medical Research Council, Wellcome Trust

المصدر: 13 ; 1

Relation: Nature Communications; http://hdl.handle.net/10044/1/100020; MC_UP_1102/5; 206292/C/17/Z

الاتاحة: http://hdl.handle.net/10044/1/100020
https://doi.org/10.1038/s41467-022-33503-6

المؤلفون: Novo, CL, Wong, E, Hockings, C, Poudel, C, Sheekey, E, Wiese, M, Okkenhaug, H, Boulton, SJ, Basu, S, Walker, S, Schierle, GSK, Narlikar, GJ, Rugg-Gunn, PJ

المصدر: 16 ; 1

Relation: Nature Communications; http://hdl.handle.net/10044/1/101827

الاتاحة: http://hdl.handle.net/10044/1/101827
https://doi.org/10.1038/s41467-022-31198-3

المؤلفون: Hewitt, G, Borel, V, Segura-Bayona, S, Takaki, T, Ruis, P, Bellelli, R, Lehmann, LC, Sommerova, L, Vancevska, A, Tomas-Loba, A, Zhu, K, Cooper, C, Fugger, K, Patel, H, Goldstone, R, Schneider-Luftman, D, Herbert, E, Stamp, G, Brough, R, Pettitt, S, Lord, CJ, West, SC, Ahel, I, Ahel, D, Chapman, JR, Deindl, S, Boulton, SJ

Relation: https://ora.ox.ac.uk/objects/uuid:a1913c02-da1f-4399-85e8-d5d2cf2265d3; https://doi.org/10.1016/j.molcel.2020.12.006

الاتاحة: https://doi.org/10.1016/j.molcel.2020.12.006
https://ora.ox.ac.uk/objects/uuid:a1913c02-da1f-4399-85e8-d5d2cf2265d3

المؤلفون: Zatreanu, D, Robinson, HMR, Alkhatib, O, Boursier, M, Finch, H, Geo, L, Grande, D, Grinkevich, V, Heald, RA, Langdon, S, Majithiya, J, McWhirter, C, Martin, NMB, Moore, S, Neves, J, Rajendra, E, Ranzani, M, Schaedler, T, Stockley, M, Wiggins, K, Brough, R, Sridhar, S, Gulati, A, Shao, N, Badder, LM, Novo, D, Knight, EG, Marlow, R, Haider, S, Callen, E, Hewitt, G, Schimmel, J, Prevo, R, Alli, C, Ferdinand, A, Bell, C, Blencowe, P, Bot, C, Calder, M, Charles, M, Curry, J, Ekwuru, T, Ewings, K, Krajewski, W, MacDonald, E, McCarron, H, Pang, L, Pedder, C, Rigoreau, L, Swarbrick, M, Wheatley, E, Willis, S, Wong, AC, Nussenzweig, A, Tijsterman, M, Tutt, A, Boulton, SJ, Higgins, GS, Pettitt, SJ, Smith, GCM, Lord, CJ

المساهمون: Haider, Syed, Pettitt, Stephen, Lord, Christopher

مصطلحات موضوعية: Organoids, Cell Line, Tumor, Animals, Humans, Mice, Rats, Ovarian Neoplasms, DNA Damage, Deoxyribonucleases, DNA-Directed DNA Polymerase, Cell Cycle Proteins, DNA-Binding Proteins, BRCA1 Protein, BRCA2 Protein, Nucleic Acid Synthesis Inhibitors, Drug Screening Assays, Antitumor, Inhibitory Concentration 50, Apoptosis, Cell Proliferation, Cell Survival, DNA Repair, Allosteric Regulation, Drug Resistance, Neoplasm, Female, Homologous Recombination, Poly(ADP-ribose) Polymerase Inhibitors, Tumor Suppressor p53-Binding Protein 1

وصف الملف: Electronic; ?; application/pdf

Relation: Nature communications, 2021, 12 (1), pp. 3636 - ?; https://repository.icr.ac.uk/handle/internal/4762

الاتاحة: https://repository.icr.ac.uk/handle/internal/4762
https://doi.org/10.1038/s41467-021-23463-8

المؤلفون: Belan, O, Moore, G, Kaczmarczyk, A, Newton, MD, Anand, R, Boulton, SJ, Rueda, DS

المصدر: 18 ; 1

مصطلحات موضوعية: Microscopy, Molecular/Chemical Probes, Single-molecule Assays

جغرافية الموضوع: United States

Relation: STAR Protocols; http://hdl.handle.net/10044/1/93360

الاتاحة: http://hdl.handle.net/10044/1/93360
https://doi.org/10.1016/j.xpro.2021.100588

المؤلفون: Anand, R, Buechelmaier, E, Belan, O, Newton, M, Vancevska, A, Kaczmarczyk, A, Takaki, T, Rueda, DS, Powell, SN, Boulton, SJ

المصدر: 273 ; 268

Relation: Nature; http://hdl.handle.net/10044/1/101021

الاتاحة: http://hdl.handle.net/10044/1/101021
https://doi.org/10.1038/s41586-021-04261-0

المؤلفون: Zondervan, JR, Stokes, M, Boulton, SJ, Telfer, MW, Mather, AE

مصطلحات موضوعية: collisional mountain belt, drainage divide, rock strength, erodibility, High Atlas

وصف الملف: 0-0; application/pdf

Relation: E-ISSN:1385-013X; 116221; http://hdl.handle.net/10026.1/15474

الاتاحة: http://hdl.handle.net/10026.1/15474
https://doi.org/10.1016/j.epsl.2020.116221

المؤلفون: Bellelli, R, Boulton, SJ

مصطلحات موضوعية: DNA replication, genome stability, human genetic disease, replisome

Relation: Trends in Genetics; Roberto Bellelli, Simon J. Boulton, Spotlight on the Replisome: Aetiology of DNA Replication-Associated Genetic Diseases, Trends in Genetics, 2020, https://doi.org/10.1016/j.tig.2020.09.008.; https://qmro.qmul.ac.uk/xmlui/handle/123456789/68640

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/68640
https://doi.org/10.1016/j.tig.2020.09.008

المؤلفون: Belan, O, Barroso, C, Kaczmarczyk, A, Anand, R, Federico, S, O’Reilly, N, Newton, MD, Maeots, E, Enchev, RI, Martinez-Perez, E, Rueda, DS, Boulton, SJ

المساهمون: Medical Research Council, Wellcome Trust

المصدر: 1073.e7 ; 1058

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, Cell Biology, BRCA2, DNA repair, Rad51 nucleoprotein filaments, Rad51 paralogs, homologous recombination, single molecule approaches, Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Carrier Proteins, DNA Breaks, Double-Stranded, DNA, Helminth, DNA-Binding Proteins, Gene Expression Regulation, Molecular Chaperones, Mutation, Protein Binding, Rad51 Recombinase, Recombinational DNA Repair, Replication Protein A, Signal Transduction, Single Molecule Imaging, 06 Biological Sciences, 11 Medical and Health Sciences

Relation: Molecular Cell; http://hdl.handle.net/10044/1/87782; MC_UP_1102/5; 206292/C/17/Z

الاتاحة: http://hdl.handle.net/10044/1/87782
https://doi.org/10.1016/j.molcel.2020.12.020