المؤلفون: Bierlaagh, Marlou C., Ramalho, Anabela S., Silva, Iris A.L., Vonk, Annelotte M., van den Bor, Rutger M., van Mourik, Peter, Pott, Johanna, Suen, Sylvia W.F., Boj, Sylvia F., Vries, Robert G.J., Lammertyn, Elise, Vermeulen, François, Amaral, Margarida D., de Boeck, Kris, van der Ent, Cornelis K., Beekman, Jeffrey M.

المساهمون: Longziekten onderzoek 1, Regenerative Medicine and Stem Cells, Beleid & Communicatie, CTM & Statistical consultation, Circulatory Health, JC onderzoeksprogramma Methodologie, Arts Assistenten Longziekten, Longziekten patientenzorg, Speerpunt Child Health, Child Health, Infection & Immunity, Longziekten onderzoek 2, Onderzoek

مصطلحات موضوعية: Cystic fibrosis, Forskolin-induced swelling assay, Patient-derived intestinal organoids, Precision medicine, Repeatability, Reproducibility, Pediatrics, Perinatology, and Child Health, Pulmonary and Respiratory Medicine

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/455667

الاتاحة: https://dspace.library.uu.nl/handle/1874/455667

المؤلفون: Smabers, Lidwien P, Wensink, Emerens, Verissimo, Carla S, Koedoot, Esmee, Pitsa, Katerina-Chara, Huismans, Maarten A, Higuera Barón, Celia, Doorn, Mayke, Valkenburg-van Iersel, Liselot B, Cirkel, Geert A, Brousali, Anneta, Overmeer, René, Koopman, Miriam, Braat, Manon N, Penning de Vries, Bas, Elias, Sjoerd G, Vries, Robert G, Kranenburg, Onno, Boj, Sylvia F, Roodhart, Jeanine M

المساهمون: Onderzoek Medische Oncologie, Cancer, Unit Opleiding Aios, CMM Groep Snippert, MS Hematologie, MS Medische Oncologie, MS CGO, CMM Groep Bos, MS Radiologie, Epi Kanker Team C, JC onderzoeksprogramma Kanker, Hubrecht Institute with UMC

مصطلحات موضوعية: Cancer, Chemotherapy, Colorectal cancer, Drug screening, Oncology, Organoids, Precision medicine, Cancer Research

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/453394

الاتاحة: https://dspace.library.uu.nl/handle/1874/453394

المؤلفون: Smabers, Lidwien P, Wensink, Emerens, Verissimo, Carla S, Koedoot, Esmee, Pitsa, Katerina-Chara, Huismans, Maarten A, Higuera Barón, Celia, Doorn, Mayke, Valkenburg-van Iersel, Liselot B, Cirkel, Geert A, Brousali, Anneta, Overmeer, René, Koopman, Miriam, Braat, Manon N, Penning de Vries, Bas, Elias, Sjoerd G, Vries, Robert G, Kranenburg, Onno, Boj, Sylvia F, Roodhart, Jeanine M

المصدر: Smabers , L P , Wensink , E , Verissimo , C S , Koedoot , E , Pitsa , K-C , Huismans , M A , Higuera Barón , C , Doorn , M , Valkenburg-van Iersel , L B , Cirkel , G A , Brousali , A , Overmeer , R , Koopman , M , Braat , M N , Penning de Vries , B , Elias , S G , Vries , R G , Kranenburg , O , Boj , S F & Roodhart , J M 2024 , ' Organoids as a ....

مصطلحات موضوعية: Cancer, Chemotherapy, Colorectal cancer, Drug screening, Oncology, Organoids, Precision medicine, Humans, Irinotecan/pharmacology therapeutic use, Oxaliplatin/pharmacology therapeutic use, Colorectal Neoplasms/drug therapy genetics, Acetylcysteine/therapeutic use, Fluorouracil/pharmacology therapeutic use, Colonic Neoplasms/drug therapy, Antineoplastic Combined Chemotherapy Protocols/adverse effects

Relation: https://cris.maastrichtuniversity.nl/en/publications/8bfe0b17-e7ae-48ee-b21f-f9d5074cf3d1

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/8bfe0b17-e7ae-48ee-b21f-f9d5074cf3d1
https://doi.org/10.1186/s13046-024-02980-6

المؤلفون: Miao, Yi, Ha, Andrew, de Lau, Wim, Yuki, Kanako, Santos, António JM, You, Changjiang, Geurts, Maarten H, Puschhof, Jens, Pleguezuelos-Manzano, Cayetano, Peng, Weng Chuan, Senlice, Ramazan, Piani, Carol, Buikema, Jan W, Gbenedio, Oghenekevwe M, Vallon, Mario, Yuan, Jenny, de Haan, Sanne, Hemrika, Wieger, Rösch, Kathrin, Dang, Luke T, Baker, David, Ott, Melanie, Depeille, Philippe, Wu, Sean M, Drost, Jarno, Nusse, Roeland, Roose, Jeroen P, Piehler, Jacob, Boj, Sylvia F, Janda, Claudia Y, Clevers, Hans, Kuo, Calvin J, Garcia, K Christopher

المصدر: Cell Stem Cell. 27(5)

مصطلحات موضوعية: Biotechnology, Digestive Diseases, Regenerative Medicine, Frizzled Receptors, Hepatocytes, Organoids, Stem Cells, Wnt Signaling Pathway, DARPin, Frizzled, Wnt, canonical Wnt signaling, organoids, protein engineering, regenerative medicine, stem cell, surrogate Wnt, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9852f8p2

المؤلفون: Mertens, Sander, Huismans, Maarten A, Verissimo, Carla S, Ponsioen, Bas, Overmeer, Rene, Proost, Natalie, van Tellingen, Olaf, van de Ven, Marieke, Begthel, Harry, Boj, Sylvia F, Clevers, Hans, Roodhart, Jeanine M L, Bos, Johannes L, Snippert, Hugo J G

المساهمون: CMM Groep Snippert, Cancer, CMM Groep Bos, Hubrecht Institute with UMC, CMM, MS Medische Oncologie, CMM Groep Van Mil

مصطلحات موضوعية: colorectal cancer, CP: Cancer, CP: Stem cell research, image-based drug screening, microtubule-targeting agents, organoids, targeted therapy, General Biochemistry,Genetics and Molecular Biology, Journal Article

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/449102

الاتاحة: https://dspace.library.uu.nl/handle/1874/449102

المؤلفون: Jelinsky, Scott A, Derksen, Merel, Bauman, Eric, Verissimo, Carla S, van Dooremalen, Wies T M, Roos, Jamie Lee, Higuera Barón, Celia, Caballero-Franco, Celia, Johnson, Bryce G, Rooks, Michelle G, Pott, Johanna, Oldenburg, Bas, Vries, Robert G J, Boj, Sylvia F, Kasaian, Marion T, Pourfarzad, Farzin, Rosadini, Charles V

المساهمون: MS MDL 1, Infection & Immunity

مصطلحات موضوعية: Cytokines/metabolism, Epithelial Cells/metabolism, Humans, Inflammatory Bowel Diseases/pathology, Intestinal Mucosa/pathology, Intestines/physiology, Organoids/metabolism, Tumor Necrosis Factor-alpha/pharmacology, barrier function, cell differentiation, organoids, tofacitinib, Gastroenterology, Immunology and Allergy, Journal Article

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/447481

الاتاحة: https://dspace.library.uu.nl/handle/1874/447481

المؤلفون: Kourula, Stephanie, Derksen, Merel, Jardi, Ferran, Jonkers, Sophie, van Heerden, Marjolein, Verboven, Peter, Theuns, Veronique, Van Asten, Stijn, Huybrechts, Tinne, Kunze, Annett, Frazer-Mendelewska, Ewa, Lai, Ka Wai, Overmeer, René, Roos, Jamie Lee, Vries, Robert G.J., Boj, Sylvia F., Monshouwer, Mario, Pourfarzad, Farzin, Snoeys, Jan

المصدر: European Journal of Pharmaceutical Sciences ; volume 188, page 106481 ; ISSN 0928-0987

الاتاحة: http://dx.doi.org/10.1016/j.ejps.2023.106481
https://api.elsevier.com/content/article/PII:S0928098723001112?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0928098723001112?httpAccept=text/plain

المؤلفون: Boj, Sylvia F, Hwang, Chang-Il, Baker, Lindsey A, Engle, Dannielle D, Tuveson, David A, Clevers, Hans

المصدر: Molecular & Cellular Oncology. 3(1)

مصطلحات موضوعية: Digestive Diseases, Rare Diseases, Cancer, Diabetes, Pancreatic Cancer, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being, cancer, pancreatic ductal adenocarcinoma, organoids, preclinical models

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7tt256mg

المؤلفون: Hwang, Chang-Il, Boj, Sylvia F, Clevers, Hans, Tuveson, David A

المصدر: The Journal of Pathology. 238(2)

مصطلحات موضوعية: Cancer, Pancreatic Cancer, Biotechnology, Rare Diseases, Digestive Diseases, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Animals, Carcinoma, Pancreatic Ductal, Cell Culture Techniques, Cell Line, Tumor, Disease Models, Animal, Drug Evaluation, Preclinical, Humans, Mice, Neoplasm Transplantation, Pancreatic Neoplasms, Transplantation, Heterologous, pancreatic cancer, organoid, preclinical model, patient-derived tumour xenograft, Clinical Sciences, Pathology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3tk1h7cd

المؤلفون: Onderzoek Medische Oncologie, Cancer, Unit Opleiding Aios, CMM Groep Snippert, MS Hematologie, MS Medische Oncologie, MS CGO, CMM Groep Bos, MS Radiologie, Epi Kanker Team C, JC onderzoeksprogramma Kanker, Hubrecht Institute with UMC, Smabers, Lidwien P, Wensink, Emerens, Verissimo, Carla S, Koedoot, Esmee, Pitsa, Katerina-Chara, Huismans, Maarten A, Higuera Barón, Celia, Doorn, Mayke, Valkenburg-van Iersel, Liselot B, Cirkel, Geert A, Brousali, Anneta, Overmeer, René, Koopman, Miriam, Braat, Manon N, Penning de Vries, Bas, Elias, Sjoerd G, Vries, Robert G, Kranenburg, Onno, Boj, Sylvia F, Roodhart, Jeanine M

URL: https://doi.org/10.1186/s13046-024-02980-6
http://hdl.handle.net/1874/453394
https://dspace.library.uu.nl/handle/1874/453394
http://www.scopus.com/inward/record.url?scp=85186227487&partnerID=8YFLogxK
1756-9966
Journal of experimental & clinical cancer research
43
1
1
16
61

المؤلفون: Longziekten onderzoek 1, Regenerative Medicine and Stem Cells, Beleid & Communicatie, CTM & Statistical consultation, Circulatory Health, JC onderzoeksprogramma Methodologie, Arts Assistenten Longziekten, Longziekten patientenzorg, Speerpunt Child Health, Child Health, Infection & Immunity, Longziekten onderzoek 2, Onderzoek, Bierlaagh, Marlou C., Ramalho, Anabela S., Silva, Iris A.L., Vonk, Annelotte M., van den Bor, Rutger M., van Mourik, Peter, Pott, Johanna, Suen, Sylvia W.F., Boj, Sylvia F., Vries, Robert G.J., Lammertyn, Elise, Vermeulen, François, Amaral, Margarida D., de Boeck, Kris, van der Ent, Cornelis K., Beekman, Jeffrey M.

URL: https://doi.org/10.1016/j.jcf.2024.04.014
http://hdl.handle.net/1874/455667
https://dspace.library.uu.nl/handle/1874/455667
http://www.scopus.com/inward/record.url?scp=85192789662&partnerID=8YFLogxK
1569-1993
Journal of Cystic Fibrosis
23
4
693
702

المؤلفون: Küçükköse, Emre, Heesters, Balthasar A, Villaudy, Julien, Verheem, André, Cercel, Madalina, van Hal, Susan, Boj, Sylvia F, Borel Rinkes, Inne H M, Punt, Cornelis J A, Roodhart, Jeanine M L, Laoukili, Jamila, Koopman, Miriam, Spits, Hergen, Kranenburg, Onno

المساهمون: Lab Translational Oncology, Cancer, Hubrecht Institute with UMC, MS CGO, Regenerative Medicine and Stem Cells, Epi Kanker Team B, MS Medische Oncologie

مصطلحات موضوعية: Animals, Ascites, Colorectal Neoplasms/drug therapy, Cytokines/metabolism, Immune Checkpoint Inhibitors/pharmacology, Liver Neoplasms, Mice, Peritoneal Neoplasms/drug therapy, Peritoneum/metabolism, Transforming Growth Factor beta3, Molecular Medicine, Oncology, Cancer Research, Immunology and Allergy, Pharmacology, Immunology, Journal Article

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/448076

الاتاحة: https://dspace.library.uu.nl/handle/1874/448076

المؤلفون: Herpers, Bram, Eppink, Berina, James, Mark I., Cortina, Carme, Cañellas Socias, Adrià, Boj, Sylvia F., Hernando Momblona, Xavier, Glodzik, Dominik, Roovers, Rob C., Wetering, Marc van de, Bartelink Clements, Carina, Zondag van der Zande, Vanessa, García Mateos, Jara, Yan, Kuan, Salinaro, Lucia, Basmeleh, Abdoul, Fatrai, Szabolc, Maussang, David, Lammerts van Bueren, Jeroen J., Chicote, Irene, Serna, Garazi, Cabellos, Laia, Ramírez, Lorena, Nuciforo, Paolo, Salazar Soler, Ramón, Santos, Cristina, Villanueva Garatachea, Alberto, Attolini, Stephan-Otto, Sancho, Elena, Palmer, Hector G., Tabernero Caturla, Josep, Stratton, Michael R., Kruif, John de, Logtenberg, Ton, Clevers, Hans, Price, Leo S., Vries, Robert, Batlle, Eduard, Throsby, Mark

المصدر: Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))

مصطلحات موضوعية: Càncer colorectal, Desenvolupament de medicaments, Colorectal cancer, Drug development

وصف الملف: 36 p.; application/pdf

Relation: Postprint del document publicat a: https://doi.org/10.1038/s43018-022-00359-0; Nature Cancer, 2022, num. 3, p. 418–436; https://doi.org/10.1038/s43018-022-00359-0; http://hdl.handle.net/2445/191089; 6549334

الاتاحة: http://hdl.handle.net/2445/191089

المؤلفون: Jelinsky, Scott A, Derksen, Merel, Bauman, Eric, Verissimo, Carla S, van Dooremalen, Wies T M, Roos, Jamie Lee, Higuera Barón, Celia, Caballero-Franco, Celia, Johnson, Bryce G, Rooks, Michelle G, Pott, Johanna, Oldenburg, Bas, Vries, Robert G J, Boj, Sylvia F, Kasaian, Marion T, Pourfarzad, Farzin, Rosadini, Charles V

المصدر: Inflammatory Bowel Diseases ; volume 29, issue 2, page 195-206 ; ISSN 1078-0998 1536-4844

الاتاحة: http://dx.doi.org/10.1093/ibd/izac212
https://academic.oup.com/ibdjournal/advance-article-pdf/doi/10.1093/ibd/izac212/46950126/izac212.pdf
https://academic.oup.com/ibdjournal/article-pdf/29/2/195/49005760/izac212.pdf

المؤلفون: Boj, Sylvia F, Hwang, Chang-Il, Baker, Lindsey A, Chio, Iok In Christine, Engle, Dannielle D, Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano, Tiriac, Hervé, Spector, Mona S, Gracanin, Ana, Oni, Tobiloba, Yu, Kenneth H, van Boxtel, Ruben, Huch, Meritxell, Rivera, Keith D, Wilson, John P, Feigin, Michael E, Öhlund, Daniel, Handly-Santana, Abram, Ardito-Abraham, Christine M, Ludwig, Michael, Elyada, Ela, Alagesan, Brinda, Biffi, Giulia, Yordanov, Georgi N, Delcuze, Bethany, Creighton, Brianna, Wright, Kevin, Park, Youngkyu, Morsink, Folkert HM, Molenaar, I Quintus, Borel Rinkes, Inne H, Cuppen, Edwin, Hao, Yuan, Jin, Ying, Nijman, Isaac J, Iacobuzio-Donahue, Christine, Leach, Steven D, Pappin, Darryl J, Hammell, Molly, Klimstra, David S, Basturk, Olca, Hruban, Ralph H, Offerhaus, George Johan, Vries, Robert GJ, Clevers, Hans, Tuveson, David A

المصدر: Cell. 160(1-2)

مصطلحات موضوعية: Pancreas, Organoids, Animals, Mice, Inbred C57BL, Humans, Mice, Mice, Nude, Carcinoma, Pancreatic Ductal, Pancreatic Neoplasms, Organ Culture Techniques, Models, Biological, Cancer, Pancreatic Cancer, Rare Diseases, Biotechnology, Digestive Diseases, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0x22s042

المؤلفون: Ponsioen, Bas, Post, Jasmin B., Buissant des Amorie, Julian R., Laskaris, Dimitrios, van Ineveld, Ravian L., Kersten, Simone, Bertotti, Andrea, Sassi, Francesco, Sipieter, François, Cappe, Benjamin, Mertens, Sander, VerlaanKlink, Ingrid, Boj, Sylvia F., Vries, Rob G.J., Rehmann, Holger, Vandenabeele, Peter, Riquet, Franck B., Trusolino, Livio, Bos, Johannes L., Snippert, Hugo J.G.

مصطلحات موضوعية: Colorectal cancer, patient-derived organoids, FRET biosensors, cell-to-cell heterogeneity, ERK oscillations, oncogenic signaling, pan-HER inhibition, EGFR

Relation: https://zenodo.org/communities/colossusprojecteu; https://zenodo.org/communities/eu; oai:zenodo.org:7801498

الاتاحة: https://doi.org/10.1038/s41556-021-00654-5

المؤلفون: De Crignis, Elisa, Hossain, Tanvir, Romal, Shahla, Carofiglio, Fabrizia, Moulos, Panagiotis, Khalid, Mir Mubashir, Rao, Shringar, Bazrafshan, Ameneh, Verstegen, Monique M.A., Pourfarzad, Farzin, Koutsothanassis, Christina, Gehart, Helmuth, Kan, Tsung Wai, Palstra, Robert Jan, Boucher, Charles, Ijzermans, Jan M.N., Huch, Meritxell, Boj, Sylvia F., Vries, Robert, Clevers, Hans, van der Laan, Luc, Hatzis, Pantelis, Mahmoudi, Tokameh

المساهمون: Hubrecht Institute with UMC

مصطلحات موضوعية: General Neuroscience, General Biochemistry,Genetics and Molecular Biology, General Immunology and Microbiology

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/445573

الاتاحة: https://dspace.library.uu.nl/handle/1874/445573

المؤلفون: de Poel, Eyleen, Spelier, Sacha, Korporaal, Ricardo, Lai, Ka Wai, Boj, Sylvia F., Conrath, Katja, van der Ent, Cornelis K., Beekman, Jeffrey M.

المساهمون: Longziekten onderzoek 2, Hubrecht Institute with UMC, Longziekten patientenzorg, Speerpunt Child Health, Child Health, Infection & Immunity, Onderzoek, Regenerative Medicine and Stem Cells

مصطلحات موضوعية: CFTR, CFTR modulator therapy, cystic fibrosis, F508del, forskolin induced swelling assay, intestinal organoids, personalized medicine, Biochemistry, Genetics and Molecular Biology (miscellaneous), Molecular Biology

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/445352

الاتاحة: https://dspace.library.uu.nl/handle/1874/445352

المؤلفون: Küçükköse, Emre, Wensink, G. Emerens, Roelse, Celine M., van Schelven, Susanne J., Raats, Daniëlle A.E., Boj, Sylvia F., Koopman, Miriam, Laoukili, Jamila, Roodhart, Jeanine M.L., Kranenburg, Onno

المساهمون: Lab Translational Oncology, Cancer, Onderzoek Medische Oncologie, Hubrecht Institute with UMC, MS Medische Oncologie, Regenerative Medicine and Stem Cells

مصطلحات موضوعية: Colorectal cancer, Deficient mismatch repair, Drug screens, Mutation, Organoids, Oncology, Cancer Research

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/444199

الاتاحة: https://dspace.library.uu.nl/handle/1874/444199

المؤلفون: Wensink, G Emerens, Elias, Sjoerd G, Mullenders, Jasper, Koopman, Miriam, Boj, Sylvia F, Kranenburg, Onno W, Roodhart, Jeanine M L

المساهمون: Onderzoek Medische Oncologie, Cancer, Epi Kanker Team A, JC onderzoeksprogramma Kanker, MS Medische Oncologie, Hubrecht Institute with UMC, Lab Translational Oncology, Regenerative Medicine and Stem Cells

مصطلحات موضوعية: Oncology, Cancer Research, Review, Journal Article

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/442626

الاتاحة: https://dspace.library.uu.nl/handle/1874/442626