المؤلفون: Behnam Nabet, Fleur M. Ferguson, Bo Kyung A. Seong, Miljan Kuljanin, Alan L. Leggett, Mikaela L. Mohardt, Amanda Robichaud, Amy S. Conway, Dennis L. Buckley, Joseph D. Mancias, James E. Bradner, Kimberly Stegmaier, Nathanael S. Gray

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/459b2972ed404c94bc46191739350a3c

المؤلفون: Kimberly Stegmaier, Jérôme Tamburini, Anthony Letai, Mark Wunderlich, Lynn H. Lee, Federica Piccioni, Scott T. Younger, Joseph D. Mancias, Jeremy A. Ryan, Biniam Adane, Sarah Mouche, Thelma Mashaka, Amy Saur Conway, Amanda L. Robichaud, Guillaume Kugener, Caroline S. Wechsler, Miljan Kuljanin, Neekesh V. Dharia, Bo Kyung A. Seong, Nastassja K. Scheidegger, Clément Larrue, Shan Lin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a00231f66c2f1f2d618c874e239af4
https://doi.org/10.1158/2159-8290.22540225.v1

المؤلفون: Kimberly Stegmaier, Jérôme Tamburini, Anthony Letai, Mark Wunderlich, Lynn H. Lee, Federica Piccioni, Scott T. Younger, Joseph D. Mancias, Jeremy A. Ryan, Biniam Adane, Sarah Mouche, Thelma Mashaka, Amy Saur Conway, Amanda L. Robichaud, Guillaume Kugener, Caroline S. Wechsler, Miljan Kuljanin, Neekesh V. Dharia, Bo Kyung A. Seong, Nastassja K. Scheidegger, Clément Larrue, Shan Lin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8b74c36b48f4b32ecfaef81a5921cb
https://doi.org/10.1158/2159-8290.c.6549322

المؤلفون: Meredith S. Irwin, David R. Kaplan, Alexander Gont, Lynn Kee, Yingying Wang, Teresa Adderley, Ivette Valencia-Sama, Robin Hallett, Bo Kyung Alex Seong, Yagnesh Ladumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1132604aca1d1ed3a06241b6d66260ec
https://doi.org/10.1158/1541-7786.22527933.v1

المؤلفون: Kimberly Stegmaier, Jérôme Tamburini, Anthony Letai, Mark Wunderlich, Lynn H. Lee, Federica Piccioni, Scott T. Younger, Joseph D. Mancias, Jeremy A. Ryan, Biniam Adane, Sarah Mouche, Thelma Mashaka, Amy Saur Conway, Amanda L. Robichaud, Guillaume Kugener, Caroline S. Wechsler, Miljan Kuljanin, Neekesh V. Dharia, Bo Kyung A. Seong, Nastassja K. Scheidegger, Clément Larrue, Shan Lin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d609241f021048a4e574176ba23569
https://doi.org/10.1158/2159-8290.22540234

المؤلفون: Meredith S. Irwin, David R. Kaplan, Alexander Gont, Lynn Kee, Yingying Wang, Teresa Adderley, Ivette Valencia-Sama, Robin Hallett, Bo Kyung Alex Seong, Yagnesh Ladumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6e03be192344009885f7284c55dfcf
https://doi.org/10.1158/1541-7786.22527945

المؤلفون: Eliezer M. Van Allen, Kimberly Stegmaier, James M. McFarland, Katherine A. Janeway, David Liu, Alexander Gusev, Francisca Vazquez, Jesse S. Boehm, Michael C. Bassik, Clement Ma, Alma Imamovic, Meng Xiao He, Felix Dietlein, Jihye Park, Kyuho Han, Brian J. Haas, Saif Alimohamed, Neekesh V. Dharia, Jake R. Conway, Jett Crowdis, Bo Kyung A. Seong, Riaz Gillani

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6582d2f9b2ed481c5900e48d37522e
https://doi.org/10.1158/0008-5472.c.6513471.v1

المؤلفون: Eliezer M. Van Allen, Kimberly Stegmaier, James M. McFarland, Katherine A. Janeway, David Liu, Alexander Gusev, Francisca Vazquez, Jesse S. Boehm, Michael C. Bassik, Clement Ma, Alma Imamovic, Meng Xiao He, Felix Dietlein, Jihye Park, Kyuho Han, Brian J. Haas, Saif Alimohamed, Neekesh V. Dharia, Jake R. Conway, Jett Crowdis, Bo Kyung A. Seong, Riaz Gillani

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f3ac9db84540d54dc0e8ce7b523a16
https://doi.org/10.1158/0008-5472.22429869

المؤلفون: David R. Kaplan, Meredith S. Irwin, Cynthia E. Hawkins, Lynn Kee, Samar Mouaaz, Lincoln D. Stein, Christina K. Yung, Robin Hallett, Kelly E. Fathers, Bo Kyung A. Seong

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1ee57c53564def9917ee6fb51d72a21f
https://doi.org/10.1158/0008-5472.c.6509016.v1

المؤلفون: David R. Kaplan, Meredith S. Irwin, Cynthia E. Hawkins, Lynn Kee, Samar Mouaaz, Lincoln D. Stein, Christina K. Yung, Robin Hallett, Kelly E. Fathers, Bo Kyung A. Seong

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413784f8d6dec04f4d29506eb5d789e5
https://doi.org/10.1158/0008-5472.22414536

المؤلفون: David R. Kaplan, Meredith S. Irwin, Cynthia E. Hawkins, Lynn Kee, Samar Mouaaz, Lincoln D. Stein, Christina K. Yung, Robin Hallett, Kelly E. Fathers, Bo Kyung A. Seong

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261542dd37447e35c181f49df15a60e9
https://doi.org/10.1158/0008-5472.22414542.v1

المؤلفون: David R. Kaplan, Meredith S. Irwin, Cynthia E. Hawkins, Lynn Kee, Samar Mouaaz, Lincoln D. Stein, Christina K. Yung, Robin Hallett, Kelly E. Fathers, Bo Kyung A. Seong

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0029b54dba442ad7595f8d2dc83024
https://doi.org/10.1158/0008-5472.22414539.v1

المؤلفون: David R. Kaplan, Meredith S. Irwin, Cynthia E. Hawkins, Lynn Kee, Samar Mouaaz, Lincoln D. Stein, Christina K. Yung, Robin Hallett, Kelly E. Fathers, Bo Kyung A. Seong

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db66261b933412ef4220ae9d243e2cc
https://doi.org/10.1158/0008-5472.22414533.v1

المؤلفون: Yagnesh Ladumor, Bo Kyung Alex Seong, Robin Hallett, Ivette Valencia-Sama, Teresa Adderley, Yingying Wang, Lynn Kee, Alexander Gont, David R. Kaplan, Meredith S. Irwin

المصدر: Mol Cancer Res

مصطلحات موضوعية: Cancer Research, Cell Survival, YAP-Signaling Proteins, Protein Serine-Threonine Kinases, Phosphoproteins, Article, Mice, Neuroblastoma, Oncology, Animals, Humans, Receptors, Calcitriol, Hippo Signaling Pathway, Neoplasm Recurrence, Local, Molecular Biology, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfa222d89e59c5d1da7b1dc170c0cb7
https://doi.org/10.1158/1541-7786.mcr-21-0425

المؤلفون: Diana Y. Lu, Jana M. Ellegast, Kenneth N. Ross, Clare F. Malone, Shan Lin, Nathaniel W. Mabe, Neekesh V. Dharia, Ashleigh Meyer, Amy Conway, Angela H. Su, Julia Selich-Anderson, Cenny Taslim, Andrea K. Byrum, Bo Kyung A. Seong, Biniam Adane, Nathanael S. Gray, Miguel N. Rivera, Stephen L. Lessnick, Kimberly Stegmaier

المصدر: Nature Cell Biology.

مصطلحات موضوعية: Cell Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8ff525173269ba42dfa0bb2d3cd51a98
https://doi.org/10.1038/s41556-022-01059-8

المؤلفون: Amanda L. Robichaud, Mikaela L. Mohardt, Fleur M. Ferguson, Behnam Nabet, Joseph D. Mancias, James E. Bradner, Amy Saur Conway, Alan L. Leggett, Dennis L. Buckley, Nathanael S. Gray, Bo Kyung A. Seong, Miljan Kuljanin, Kimberly Stegmaier

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Nature Communications

مصطلحات موضوعية: Male, Proteomics, 0301 basic medicine, Science, Direct control, Chemical biology, General Physics and Astronomy, Tacrolimus Binding Protein 1A, Protein Homeostasis, 01 natural sciences, Article, General Biochemistry, Genetics and Molecular Biology, Target validation, Proto-Oncogene Proteins p21(ras), Tacrolimus Binding Proteins, Gene Knockout Techniques, Mice, 03 medical and health sciences, Mice, Inbred NOD, Animals, Humans, Molecule, lcsh:Science, Mice, Knockout, Protein function, Multidisciplinary, 010405 organic chemistry, Chemistry, HEK 293 cells, Proteins, General Chemistry, Small molecule, 0104 chemical sciences, Cell biology, Mice, Inbred C57BL, HEK293 Cells, 030104 developmental biology, Von Hippel-Lindau Tumor Suppressor Protein, Models, Animal, Proteolysis, Female, lcsh:Q, Target protein, Chemical tools, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c94cdbfd9c597da926943a6f6caa324
https://doaj.org/article/459b2972ed404c94bc46191739350a3c

المؤلفون: Joseph D. Mancias, Amanda L. Robichaud, Jerome Tamburini, Clément Larrue, Federica Piccioni, Lynn Lee, Anthony Letai, Jeremy Ryan, Shan Lin, Amy Saur Conway, Nastassja K. Scheidegger, Mark Wunderlich, Scott T. Younger, Biniam Adane, Sarah Mouche, Neekesh V. Dharia, Guillaume Kugener, Bo Kyung A. Seong, Thelma Mashaka, Kimberly Stegmaier, Miljan Kuljanin, Caroline Wechsler

المساهمون: University of Zurich, Stegmaier, Kimberly

المصدر: Cancer Discov

مصطلحات موضوعية: Cell, 610 Medicine & health, Antineoplastic Agents, Computational biology, Article, chemistry.chemical_compound, Genome editing, In vivo, hemic and lymphatic diseases, medicine, CRISPR, Animals, Humans, Precision Medicine, neoplasms, Venetoclax, business.industry, Myeloid leukemia, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Leukemia, Myeloid, Acute, medicine.anatomical_structure, Oncology, chemistry, 10036 Medical Clinic, 2730 Oncology, CRISPR-Cas Systems, business, Genetic screen

وصف الملف: 432.pdf - application/pdf; nihms_1742496.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c56bc6680b50eddcd2ed9826b4c7ab

المؤلفون: Bo Kyung Alex Seong, Kimberly Stegmaier, Jennifer A. Perry

المصدر: Annual Review of Cancer Biology. 3:299-321

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Fusion, Chromosomal translocation, Cell Biology, Biology, medicine.disease, Fusion protein, Cell biology, Chromatin, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, medicine, Sarcoma, Epigenetics, Transcription factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4cbf3b9d97b4f41ac958bc70563a6006
https://doi.org/10.1146/annurev-cancerbio-030518-055710

المؤلفون: Eliezer M. Van Allen, Michael C. Bassik, Katherine A. Janeway, Meng Xiao He, Felix Dietlein, Neekesh V. Dharia, Clement Ma, David Liu, Jesse S. Boehm, Kyuho Han, Jett Crowdis, Jake Conway, Brian J. Haas, Francisca Vazquez, Kimberly Stegmaier, James M. McFarland, Alexander Gusev, Alma Imamovic, Bo Kyung A. Seong, Saif Alimohamed, Jihye Park, Riaz Gillani

المصدر: Cancer Res

مصطلحات موضوعية: Cancer Research, Dependency (UML), Cell Survival, Cancer, Computational biology, Biology, medicine.disease_cause, medicine.disease, Genome, Article, Oncology, Neoplasms, Cancer cell, medicine, Humans, Gene Fusion, Functional dependency, Carcinogenesis, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84c3066586a3ca26b2bda39f0d736b0
https://europepmc.org/articles/PMC8338889/

المؤلفون: Amy Saur Conway, Miljan Kuljanin, Joseph D. Mancias, Sarah Mouche, Shan Lin, Scott T. Younger, Biniam Adane, Lynn Lee, Mark Wunderlich, Federica Piccioni, Amanda L. Robichaud, Jerome Tamburini, Guillaume Kugener, Bo Kyung A. Seong, Anthony Letai, Clement Larrue, Caroline Wechsler, Thelma Mashaka, Jeremy Ryan, Neekesh V. Dharia, Kimberly Stegmaier

مصطلحات موضوعية: Venetoclax, business.industry, Apoptosis Regulator, Myeloid leukemia, Computational biology, Unmet needs, chemistry.chemical_compound, Genome editing, chemistry, In vivo, hemic and lymphatic diseases, Medicine, CRISPR, business, Genetic screen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ea3b4a8acc172ebb9484c620b520f391
https://doi.org/10.1101/2020.12.28.424340