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1
المؤلفون: Eric M. Sandberg, Raymond Dingledine, Thanh N. Doan, Amy L. Rubinstein, Timothy C. Baranowski, Temitope Aiyejorun, Audrey White, Delali Blavo, Jamil Haider, Blossom Sneed, T. Cameron Tran
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2
المؤلفون: Eric M. Sandberg, Raymond Dingledine, Thanh N. Doan, Amy L. Rubinstein, Timothy C. Baranowski, Temitope Aiyejorun, Audrey White, Delali Blavo, Jamil Haider, Blossom Sneed, T. Cameron Tran
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3
المؤلفون: Dennis C. Liotta, Iestyn Lewis, Jaeki Min, Serdar Kurtkaya, Raymond Dingledine, Lian Li, Aiming Sun, Richard K. Plemper, Yuhong Du, Blossom Sneed, Andrew Prussia, Pahk Thepchatri, James P. Snyder, Thota Ganesh, Haian Fu
المصدر: Current Topics in Medicinal Chemistry. 9:1159-1171
مصطلحات موضوعية: Virtual screening, Databases, Factual, biology, Chemistry, Pharmaceutical, Drug Evaluation, Preclinical, Cancer, General Medicine, Computational biology, biology.organism_classification, Bioinformatics, medicine.disease, Small molecule, Article, Virus, Measles virus, Drug Design, Molecular Probes, Neoplasms, Transgenic zebrafish, Viruses, Drug Discovery, medicine, Animals, Data Mining, Chemical design
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4
المؤلفون: Jamil Haider, Raymond Dingledine, Eric M. Sandberg, T. Cameron Tran, Amy L. Rubinstein, Audrey White, Delali Blavo, Thanh Doan, Timothy C. Baranowski, Blossom Sneed, Temitope Aiyejorun
المصدر: Cancer Research. 67:11386-11392
مصطلحات موضوعية: Umbilical Veins, Cancer Research, Embryo, Nonmammalian, Indoles, animal structures, Endothelium, Angiogenesis, Drug Evaluation, Preclinical, Neovascularization, Physiologic, Angiogenesis Inhibitors, Biology, Animals, Genetically Modified, Neovascularization, Automation, Cell Movement, Oximes, medicine, Animals, Humans, Zebrafish, Cell Proliferation, Tube formation, Drug discovery, biology.organism_classification, Molecular biology, Endothelial stem cell, medicine.anatomical_structure, Oncology, Blood Vessels, Human umbilical vein endothelial cell, Endothelium, Vascular, medicine.symptom, Algorithms, Thymidine
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5
المؤلفون: Kevin M. Walton, Jeff Ohren, John D. Knafels, Amy Rosado, Travis T. Wager, Butler Todd W, Andy N. Mead, Blossom Sneed, Katherine Fisher, David Horton, Shenping Liu, George J DeMarco, Scot Richard Mente, Helen Berke, Angela C. Doran, Cheng Chang, Jenifer Bradley, Michael Marconi, Ramalakshmi Yegna Chandrasekaran, David M. Rubitski
المصدر: ACS chemical neuroscience. 5(12)
مصطلحات موضوعية: Time Factors, Physiology, Cognitive Neuroscience, Drug-Seeking Behavior, Self Administration, Biology, Pharmacology, Biochemistry, Rats, Sprague-Dawley, Mice, In vivo, Casein Kinase I, medicine, Potency, Animals, Humans, Kinome, Enzyme Inhibitors, IC50, Analysis of Variance, Cross-Over Studies, Dose-Response Relationship, Drug, Kinase, Cell Biology, General Medicine, Isoxazoles, Circadian Rhythm, Rats, Analgesics, Opioid, Fentanyl, Mice, Inbred C57BL, Macaca fascicularis, Protein Transport, Pyrimidines, Opioid, Conditioning, Operant, Casein kinase 1, Reinforcement, Psychology, medicine.drug
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6
المؤلفون: John M. Humphrey, Shenping Liu, Jeff Ohren, Katherine Fisher, Ramalakshmi Yegna Chandrasekaran, Kevin M. Walton, Kevin Cherry, Butler Todd W, W. Scott McDonald, Eric P. Arnold, Jianke Li, Ken Dirico, Angela C. Doran, Blossom Sneed, Travis T. Wager, Subramanyam Chakrapani, Michael Eric Green, Scot Richard Mente, John D. Knafels, Matthew Merrill Hayward, Paul Galatsis, Vanessa Paradis, Michael Marconi
المصدر: Journal of medicinal chemistry. 56(17)
مصطلحات موضوعية: Gene isoform, chemistry.chemical_classification, Models, Molecular, Magnetic Resonance Spectroscopy, p38 mitogen-activated protein kinases, Circadian clock, Proteins, Ligands, Mass Spectrometry, Enzyme, Biochemistry, chemistry, In vivo, Casein Kinase Idelta, Drug Discovery, Molecular Medicine, Casein kinase 1, Circadian rhythm, Protein Kinase Inhibitors
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7
المؤلفون: Karki Kapil Kumar, Theresa J. O’Sullivan, Kenneth J. DiRico, Jason K. Dutra, Evelyn Sibley, Charles E. Nolan, Leslie R. Pustilnik, Chakrapani Subramanyam, Stacey L. Becker, Christine E. Oborski, Andrew J. Hallgren, Christopher J. O’Donnell, Yasong Lu, Bethany L. Kormos, W. Scott McDonald, Kevin Atchison, Michael Eric Green, Dorff Peter H, Steven Capetta, Annie Won, Liming Zhang, Ivan Viktorovich Efremov, Blossom Sneed, Ashley Robshaw, Antonia F. Stepan, Gregory W. Kauffman, David Riddell
المصدر: Journal of medicinal chemistry. 55(7)
مصطلحات موضوعية: Stereochemistry, Administration, Oral, Biological Availability, Stereoisomerism, Cell Line, chemistry.chemical_compound, Bridged Bicyclo Compounds, Mice, Structure-Activity Relationship, Dogs, Pentanes, Drug Discovery, Structure–activity relationship, Phenyl group, Moiety, Animals, Humans, Tissue Distribution, Oxadiazoles, Sulfonamides, biology, Bicyclic molecule, Brain, Rats, Pentane, chemistry, Enzyme inhibitor, biology.protein, Microsomes, Liver, Molecular Medicine, Female, Bioisostere, Amyloid Precursor Protein Secretases
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8
المؤلفون: Stacey L. Becker, Chakrapani Subramanyam, Hao Sun, Blossom Sneed, Ivan Viktorovich Efremov, Karki Kapil Kumar, Antonia F. Stepan, Emily Miller, Kenneth J. DiRico, R. Scott Obach, Kevin Atchison, David Riddell, W. Scott McDonald, Anthony Wood, Charles E. Nolan, Dorff Peter H, Ashley Robshaw, Evelyn Sibley, Theresa J. O’Sullivan, Leslie R. Pustilnik, Christopher J. O’Donnell, Yasong Lu, Andrew J. Hallgren, Steven Capetta, Annie Won, Jason K. Dutra
المصدر: Journal of medicinal chemistry. 54(22)
مصطلحات موضوعية: Stereochemistry, Stereoisomerism, In Vitro Techniques, Oxetane, Crystallography, X-Ray, Cell Line, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Dogs, Ethers, Cyclic, Drug Discovery, Structure–activity relationship, Animals, Humans, Tissue Distribution, Sulfonamides, Amyloid beta-Peptides, CYP3A4, biology, Receptors, Notch, Chemistry, Active site, Brain, Tetrahydropyran, Metabolism, Drug Design, Lipophilicity, biology.protein, Microsomes, Liver, Molecular Medicine, Amyloid Precursor Protein Secretases, Oxidation-Reduction
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9
المؤلفون: Sandrine M. Dupre, Andrew S. I. Loudon, Elizabeth S. Maywood, Michael H. Hastings, Travis T. Wager, Francis Rajamohan, John D. Knafels, Jeffrey F. Ohren, Jian Li, Johanna E. Chesham, Laura E. Zawadzke, Wei Qun Lu, David A. Bechtold, Kevin M. Walton, Julie E. Gibbs, Blossom Sneed, Qing-Jun Meng
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 107(34)
مصطلحات موضوعية: medicine.medical_specialty, Casein Kinase 1 epsilon, Circadian clock, Mice, Transgenic, Biology, In Vitro Techniques, Mice, Internal medicine, medicine, Animals, Circadian rhythm, Casein Kinase Idelta, RNA, Small Interfering, Protein Kinase Inhibitors, Mice, Knockout, Multidisciplinary, Base Sequence, Suprachiasmatic nucleus, Period Circadian Proteins, Casein Kinase Iepsilon, Biological Sciences, Cell biology, Circadian Rhythm, PER2, Endocrinology, Pyrimidines, Gene Knockdown Techniques, Receptors, Vasoactive Intestinal Peptide, Type II, Suprachiasmatic Nucleus, Casein kinase 1
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10Academic Journal
المؤلفون: Antonia F. Stepan, Kapil Karki, W. Scott McDonald, PeterH. Dorff, Jason K. Dutra, Kenneth J. DiRico, Annie Won, Chakrapani Subramanyam, Ivan V. Efremov, Christopher J. OâDonnell, Charles E. Nolan, Stacey L. Becker, Leslie R. Pustilnik, Blossom Sneed, Hao Sun, Yasong Lu, Ashley E. Robshaw, David Riddell, Theresa J. O'Sullivan, Evelyn Sibley
المصدر: Journal of Medicinal Chemistry; Nov2011, Vol. 54 Issue 22, p7772-7783, 12p