المؤلفون: Alissandra de Moura Gomes, Terri L. Petkau, Andrea J. Korecki, Oriol Fornes, Adriana Galvan, Ge Lu, Austin M. Hill, Siu Ling Lam, Anqi Yao, Rachelle A. Farkas, Wyeth W. Wasserman, Yoland Smith, Elizabeth M. Simpson, Blair R. Leavitt

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)

مصطلحات موضوعية: MiniPromoters, Gene therapy, Striatum, Medium spiny neurons, ADORA2A, rAAV, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/ccbb413e18624dfaadafe59f90e06ce7

المؤلفون: Nicholas S. Caron, Lauren M. Byrne, Fanny L. Lemarié, Jeffrey N. Bone, Amirah E.-E. Aly, Seunghyun Ko, Christine Anderson, Lorenzo L. Casal, Austin M. Hill, David J. Hawellek, Peter McColgan, Edward J. Wild, Blair R. Leavitt, Michael R. Hayden

المصدر: Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-22 (2024)

مصطلحات موضوعية: Neurofilament light chain, Response biomarker, Huntington's disease, Huntingtin lowering, Antisense oligonucleotide, Cerebrospinal fluid, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2047-9158

URL الوصول: https://doaj.org/article/89b2e043ae1a4ef094cfbb9512ed2741

المؤلفون: Bethany A. Adair, Andrea J. Korecki, Diana Djaksigulova, Pamela K. Wagner, Nina Y. Chiu, Siu Ling Lam, Tess C. Lengyell, Blair R. Leavitt, Elizabeth M. Simpson

المصدر: Ophthalmology and Therapy, Vol 12, Iss 4, Pp 2049-2068 (2023)

مصطلحات موضوعية: Adenine base editor, Aniridia, CRISPR gene therapy, Humanization, Lipid nanoparticles, Mouse embryonic stem cells, Ophthalmology, RE1-994

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2193-8245; https://doaj.org/toc/2193-6528

URL الوصول: https://doaj.org/article/236a9d7004ac47589a17158051a80833

المؤلفون: Benjamin Life, Terri L. Petkau, Giuliano N.F. Cruz, Erick I. Navarro-Delgado, Ning Shen, Keegan Korthauer, Blair R. Leavitt

المصدر: Neurobiology of Disease, Vol 182, Iss , Pp 106138- (2023)

مصطلحات موضوعية: Progranulin, Frontotemporal dementia, Humanized mice, Preclinical model, RNAseq, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996123001523; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/14216bfcd001432dbedbf9abe076de7e

المؤلفون: Carlos Estevez‐Fraga, Michael S. Elmalem, Marina Papoutsi, Alexandra Durr, Elin M. Rees, Nicola Z. Hobbs, Raymund A. C. Roos, Bernhard Landwehrmeyer, Blair R. Leavitt, Douglas R. Langbehn, Rachael I. Scahill, Geraint Rees, Sarah J. Tabrizi, Sarah Gregory

المصدر: Brain and Behavior, Vol 13, Iss 4, Pp n/a-n/a (2023)

مصطلحات موضوعية: diffusion tensor imaging, Huntington's disease, longitudinal, presymptomatic, symptomatic, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2162-3279

URL الوصول: https://doaj.org/article/14760f7b295f464cbc8b231b3d170168

المؤلفون: Benjamin Life, Luis E.B. Bettio, Ilse Gantois, Brian R. Christie, Blair R. Leavitt

المصدر: Current Research in Neurobiology, Vol 5, Iss , Pp 100094- (2023)

مصطلحات موضوعية: Progranulin, Fragile X Syndrome, Autism spectrum disorder, Neurodevelopment, Mouse models, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2665945X23000220; https://doaj.org/toc/2665-945X

URL الوصول: https://doaj.org/article/3f8d6fe70d1643a18042d4f2ae19847b

المؤلفون: Kristina Bečanović, Asghar Muhammad, Izabella Gadawska, Shiny Sachdeva, David Walker, Eduardo. R. Lazarowski, Sonia Franciosi, Kevin H. J. Park, Hélène C. F. Côté, Blair R. Leavitt

المصدر: npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2056-3973

URL الوصول: https://doaj.org/article/9ed44fa1c2f0480fb9c59de967a2f4ca

المؤلفون: Jack Wuyang Jin, Xuelai Fan, Esther del Cid-Pellitero, Xing-Xing Liu, Limin Zhou, Chunfang Dai, Ebrima Gibbs, Wenting He, Hongjie Li, Xiaobin Wu, Austin Hill, Blair R. Leavitt, Neil Cashman, Lidong Liu, Jie Lu, Thomas M. Durcan, Zhifang Dong, Edward A. Fon, Yu Tian Wang

المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/63d676340fd343489fc159532b920ece

المؤلفون: Marc Ciosi, Alastair Maxwell, Sarah A. Cumming, Davina J. Hensman Moss, Asma M. Alshammari, Michael D. Flower, Alexandra Durr, Blair R. Leavitt, Raymund A.C. Roos, Peter Holmans, Lesley Jones, Douglas R. Langbehn, Seung Kwak, Sarah J. Tabrizi, Darren G. Monckton

المصدر: EBioMedicine, Vol 48, Iss , Pp 568-580 (2019)

مصطلحات موضوعية: Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396419306243; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/e8c098c00c394408a8d5c2c5d49ab489

المؤلفون: Daisy Abreu, Jennifer Ware, Nellie Georgiou-Karistianis, Blair R. Leavitt, Cheryl J. Fitzer-Attas, Raquel Lobo, Ana Raquel Fernandes, Olivia Handley, Karen E. Anderson, Julie C. Stout, Cristina Sampaio

المصدر: Frontiers in Neurology, Vol 12 (2021)

مصطلحات موضوعية: Huntington's disease, clinimetrics properties, utility of measurements, clinical assessments, Enroll-HD, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2021.595679/full; https://doaj.org/toc/1664-2295

URL الوصول: https://doaj.org/article/4af292b6ce0a4ba7b3b03db1ac9ee739

المؤلفون: Terri L. Petkau, Benjamin Life, Ge Lu, Jasmine Yang, Oriol Fornes, Wyeth Wasserman, Elizabeth M. Simpson, Blair R. Leavitt

المصدر: Neurobiology of Disease, Vol 153, Iss , Pp 105314- (2021)

مصطلحات موضوعية: Progranulin, Frontotemporal dementia, Transgenic mice, Progranulin over-expression, Bacterial artificial chromosome, Hprt-targeted mice, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996121000632; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/a805011b199a45218a7ae5bae9f66a93

المؤلفون: Kristina Bečanović, Muhammad Asghar, Izabella Gadawska, Shiny Sachdeva, David Walker, Eduardo. R. Lazarowski, Sonia Franciosi, Kevin H. J. Park, Hélène C. F. Côté, Blair R. Leavitt

المصدر: npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-1 (2021)

مصطلحات موضوعية: Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2056-3973

URL الوصول: https://doaj.org/article/5efe5a202d054666aa22337aa09ee23d

المؤلفون: Lora Minkova, Sarah Gregory, Rachael I. Scahill, Ahmed Abdulkadir, Christoph P. Kaller, Jessica Peter, Jeffrey D. Long, Julie C. Stout, Ralf Reilmann, Raymund A. Roos, Alexandra Durr, Blair R. Leavitt, Sarah J. Tabrizi, Stefan Klöppel

المصدر: NeuroImage: Clinical, Vol 17, Iss , Pp 312-324 (2018)

مصطلحات موضوعية: Computer applications to medicine. Medical informatics, R858-859.7, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213158217302632; https://doaj.org/toc/2213-1582

URL الوصول: https://doaj.org/article/b4308c9929ef4302b37f33f5c7d08710

المؤلفون: Terri L. Petkau, Natalia Kosior, Kathleen de Asis, Colúm Connolly, Blair R. Leavitt

المصدر: Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)

مصطلحات موضوعية: Frontotemporal lobar degeneration, Neuronal ceroid lipofuscinosis, Progranulin, Conditional knockout mice, Neuropathology, Lysozyme promotor, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12974-017-1000-9; https://doaj.org/toc/1742-2094

URL الوصول: https://doaj.org/article/e14ab9dbd07c41d986a4400b1c13cce6

المؤلفون: Terri L. Petkau, Jake Blanco, Blair R. Leavitt

المصدر: Neurobiology of Disease, Vol 106, Iss , Pp 14-22 (2017)

مصطلحات موضوعية: Frontotemporal lobar degeneration, Neuronal ceroid lipofuscinosis, Progranulin, Conditional knockout mice, Neuropathology, Nestin, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996117301390; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/b00339e7963d4138a9e031445fd2f9ea

المؤلفون: Christopher D. Rowley, Sarah J. Tabrizi, Rachael I. Scahill, Blair R. Leavitt, Raymund A. C. Roos, Alexandra Durr, Nicholas A. Bock

المصدر: Frontiers in Neuroscience, Vol 12 (2018)

مصطلحات موضوعية: Huntington’s disease, MRI, cerebral cortex, myelin, neurodegeneration, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnins.2018.00805/full; https://doaj.org/toc/1662-453X

URL الوصول: https://doaj.org/article/5dec07ffb63d49aab552aecab8b726ca

المؤلفون: Stefan Klöppel, Sarah Gregory, Elisa Scheller, Lora Minkova, Adeel Razi, Alexandra Durr, Raymund A.C. Roos, Blair R. Leavitt, Marina Papoutsi, G. Bernhard Landwehrmeyer, Ralf Reilmann, Beth Borowsky, Hans Johnson, James A. Mills, Gail Owen, Julie Stout, Rachael I. Scahill, Jeffrey D. Long, Geraint Rees, Sarah J. Tabrizi

المصدر: EBioMedicine, Vol 2, Iss 10, Pp 1420-1429 (2015)

مصطلحات موضوعية: Huntington's disease, Preclinical, Neural compensation, MRI, Cognitive, Motor, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396415300967; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/6473b4fa7ed74c708218c20ead8cb358

المؤلفون: Ulrike Träger, Ralph Andre, Anna Magnusson-Lind, James R.C. Miller, Colúm Connolly, Andreas Weiss, Stephan Grueninger, Edina Silajdžić, Donna L. Smith, Blair R. Leavitt, Gillian P. Bates, Maria Björkqvist, Sarah J. Tabrizi

المصدر: Neurobiology of Disease, Vol 73, Iss , Pp 388-398 (2015)

مصطلحات موضوعية: Huntington's disease, Neurodegeneration, Neuroinflammation, Innate immune system, Myeloid cells, Cytokines, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996114003258; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/2bb72a14457c461b9f15b194b9926f85

المؤلفون: Eileanoir B. Johnson, Sarah Gregory, Hans J. Johnson, Alexandra Durr, Blair R. Leavitt, Raymund A. Roos, Geraint Rees, Sarah J. Tabrizi, Rachael I. Scahill

المصدر: Frontiers in Neurology, Vol 8 (2017)

مصطلحات موضوعية: gray matter, segmentation, Huntington’s disease, FreeSurfer, statistical parametric mapping, advanced normalization tools, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fneur.2017.00519/full; https://doaj.org/toc/1664-2295

URL الوصول: https://doaj.org/article/8dae0efc8f2d41bba4ec7177b690208f

المؤلفون: Jeffrey D. Long, Wayne R. Matson, Andrew R. Juhl, Blair R. Leavitt, Jane S. Paulsen

المصدر: Neurobiology of Disease, Vol 46, Iss 3, Pp 625-634 (2012)

مصطلحات موضوعية: 8OHdG, Huntington disease, Biomarker, Oxidative stress, Mitochondrial dysfunction, PREDICT-HD, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996112000678; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/b09bc08097be42ff85acabc950445403