المؤلفون: Arpita Deb, Brian D. Tow, Jie Hao, Branden L. Nguyen, Valeria Gomez, James A. Stewart, Jr, Ashley J. Smuder, Bjorn C. Knollmann, Ying Wang, Bin Liu

المصدر: Journal of Molecular and Cellular Cardiology Plus, Vol 10, Iss , Pp 100093- (2024)

مصطلحات موضوعية: RyR2 leak, Ca2+-dependent cardiomyopathy, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772976124000333; https://doaj.org/toc/2772-9761

URL الوصول: https://doaj.org/article/0d1bf4464fc44ee5952fe594a9b9b7b8

المؤلفون: Vasco Sequeira, Lili Wang, Paul J.M. Wijnker, Kyungsoo Kim, Jose R. Pinto, Cris dos Remedios, Charles Redwood, Bjorn C. Knollmann, Jolanda van der Velden

المصدر: Journal of Molecular and Cellular Cardiology Plus, Vol 1, Iss , Pp 100007- (2022)

مصطلحات موضوعية: Hypertrophic cardiomyopathy, Troponin T, Protein toxic threshold, Myofilament Ca2+-sensitivity, hiPSC-CM, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772976122000010; https://doaj.org/toc/2772-9761

URL الوصول: https://doaj.org/article/b360c922580f4c239424f598c7d8a20a

المؤلفون: Daniel J. Blackwell, Michela Faggioni, Matthew J. Wleklinski, Nieves Gomez-Hurtado, Raghav Venkataraman, Chelsea E. Gibbs, Franz J. Baudenbacher, Shiaoching Gong, Glenn I. Fishman, Patrick M. Boyle, Karl Pfeifer, Bjorn C. Knollmann

المصدر: JCI Insight, Vol 7, Iss 3 (2022)

مصطلحات موضوعية: Cardiology, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2379-3708

URL الوصول: https://doaj.org/article/2aa7c799ff5c4e1e88cbf5f6f46506a5

المؤلفون: Megan L. Rasmussen, Nilay Taneja, Abigail C. Neininger, Lili Wang, Gabriella L. Robertson, Stellan N. Riffle, Linzheng Shi, Bjorn C. Knollmann, Dylan T. Burnette, Vivian Gama

المصدر: iScience, Vol 23, Iss 4, Pp - (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004220301991; https://doaj.org/toc/2589-0042

URL الوصول: https://doaj.org/article/f025503b66d744dcac900c61af8b2bcc

المؤلفون: Natalia R. Barbaro, Jason D. Foss, Dmytro O. Kryshtal, Nikita Tsyba, Shivani Kumaresan, Liang Xiao, Raymond L. Mernaugh, Hana A. Itani, Roxana Loperena, Wei Chen, Sergey Dikalov, Jens M. Titze, Bjorn C. Knollmann, David G. Harrison, Annet Kirabo

المصدر: Cell Reports, Vol 21, Iss 4, Pp 1009-1020 (2017)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717314195; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/d1235ed70c9742e59a814cf1462c6cee

المؤلفون: James D. West, Cristi L. Galindo, Kyungsoo Kim, John Jonghyun Shin, James B. Atkinson, Ines Macias‐Perez, Leo Pavliv, Bjorn C. Knollmann, Jonathan H. Soslow, Larry W. Markham, Erica J. Carrier

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 21 (2019)

مصطلحات موضوعية: Duchenne muscular dystrophy cardiomyopathy, receptor blocker, TC receptor, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2047-9980

URL الوصول: https://doaj.org/article/95214a90e2ad4dbbb0a6b21eedf73060

المؤلفون: Hyun Seok Hwang, Marcelo P. Baldo, Jose Pindado Rodriguez, Michela Faggioni, Bjorn C. Knollmann

المصدر: Frontiers in Physiology, Vol 10 (2019)

مصطلحات موضوعية: catecholaminergic polymorphic ventricular tachycardia, flecainide, calcium overload, calsequestrin (Casq2), cardiac ryanodine receptor (RyR2), Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphys.2019.00992/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/7a8cdd7d12e6422da437a496cba011b3

المؤلفون: Przemysław B. Radwański, PharmD, PhD, Hsiang-Ting Ho, PhD, Rengasayee Veeraraghavan, PhD, Lucia Brunello, PhD, Bin Liu, PhD, Andriy E. Belevych, PhD, Sathya D. Unudurthi, PhD, Michael A. Makara, PhD, Silvia G. Priori, MD, PhD, Pompeo Volpe, PhD, Antonis A. Armoundas, PhD, Wolfgang H. Dillmann, MD, Bjorn C. Knollmann, MD, PhD, Peter J. Mohler, PhD, Thomas J. Hund, PhD, Sándor Györke, PhD

المصدر: JACC: Basic to Translational Science, Vol 1, Iss 4, Pp 251-266 (2016)

مصطلحات موضوعية: β-adrenergic receptor, diastolic Ca2+ release, neuronal Na+ channels, ventricular arrhythmias, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452302X16300250; https://doaj.org/toc/2452-302X

URL الوصول: https://doaj.org/article/14f969abcf034b40ad9a83088e11255d

المؤلفون: Bin Liu, Shane D. Walton, Hsiang‐Ting Ho, Andriy E. Belevych, Svetlana B. Tikunova, Ingrid Bonilla, Vikram Shettigar, Bjorn C. Knollmann, Silvia G. Priori, Pompeo Volpe, Przemysław B. Radwański, Jonathan P. Davis, Sándor Györke

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 10 (2018)

مصطلحات موضوعية: arrhythmia (mechanisms), calcium channel, calcium signaling, calmodulin, gene therapy, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2047-9980

URL الوصول: https://doaj.org/article/17b2d1203c6b4fb18ec412e87dd32e52

المؤلفون: Björn C. Knollmann, Kenji Suita, Masanari Umemura, Rajesh Prajapati, Satoshi Okumura, Takashi Nakamura, Takayuki Fujita, Utako Yokoyama, Wenqian Cai, Yoshihiro Ishikawa, Yuko Hidaka

المصدر: Circulation Journal. 2019, 83(2):295

المؤلفون: Dina Myers Stroud, Tao Yang, Kevin Bersell, Dymtro O. Kryshtal, Satomi Nagao, Christian Shaffer, Laura Short, Lynn Hall, Thomas C. Atack, Wei Zhang, Bjorn C. Knollmann, Franz Baudenbacher, Dan M. Roden

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 11 (2016)

مصطلحات موضوعية: sodium channels, transgenic mice, ventricular arrhythmia, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2047-9980

URL الوصول: https://doaj.org/article/96d4eb6c34384766b19fc6f104706092

المؤلفون: Pooja Joshi, Shanea Estes, Deeptankar DeMazumder, Bjorn C Knollmann, Swati Dey

المصدر: eLife, Vol 12 (2023)

مصطلحات موضوعية: guinea pig, cavia porcellus, murine, Medicine, Science, Biology (General), QH301-705.5

Relation: https://elifesciences.org/articles/88638; https://doaj.org/toc/2050-084X; RP88638; https://doaj.org/article/7ab20141589e45118ed66b0577d066e3

الاتاحة: https://doi.org/10.7554/eLife.88638
https://doaj.org/article/7ab20141589e45118ed66b0577d066e3

المؤلفون: Daniel J. Clemens, Dan Ye, Lili Wang, C.S. John Kim, Wei Zhou, Steven M. Dotzler, David J. Tester, Isabelle Marty, Bjorn C. Knollmann, Michael J. Ackerman

المصدر: Stem Cell Reports. 18:1075-1089

مصطلحات موضوعية: Genetics, Cell Biology, Biochemistry, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8ef33b0b7f0f0400f4f4453c33d81af7
https://doi.org/10.1016/j.stemcr.2023.04.005

المؤلفون: Daniel J. Blackwell, Abigail N. Smith, Tri Do, Aaron Gochman, Jeffrey Schmeckpeper, Corey R. Hopkins, Wendell S. Akers, Jeffrey N. Johnston, Bjorn C. Knollmann

المصدر: Journal of Pharmacology and Experimental Therapeutics. 385:205-213

مصطلحات موضوعية: Pharmacology, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::073231b528eb2db647e4ec425d76b31d
https://doi.org/10.1124/jpet.122.001455

المؤلفون: Kevin R. Bersell, Tao Yang, Jonathan D. Mosley, Andrew M. Glazer, Andrew T. Hale, Dmytro O. Kryshtal, Kyungsoo Kim, Jeffrey D. Steimle, Jonathan D. Brown, Joe-Elie Salem, Courtney C. Campbell, Charles C. Hong, Quinn S. Wells, Amanda N. Johnson, Laura Short, Marcia A. Blair, Elijah R. Behr, Evmorfia Petropoulou, Yalda Jamshidi, Mark D. Benson, Michelle J. Keyes, Debby Ngo, Ramachandran S. Vasan, Qiong Yang, Robert E. Gerszten, Christian Shaffer, Shan Parikh, Quanhu Sheng, Prince J. Kannankeril, Ivan P. Moskowitz, John D. York, Thomas J. Wang, Bjorn C. Knollmann, Dan M. Roden

المصدر: Circulation. 147:824-840

مصطلحات موضوعية: Physiology (medical), Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcdd1ac34ae82ff8a9ad6eaf1e5d9d09
https://doi.org/10.1161/circulationaha.122.062193

المؤلفون: Abigail N. Smith (10936236), Daniel J. Blackwell (10130838), Bjorn C. Knollmann (6834848), Jeffrey N. Johnston (1321833)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, submicromolar potency provided, selectivity characteristics necessary, hydrogen bond contacts, functional group changes, dramatically affect potency, dimensional space occupied, cyclic oligomeric depsipeptide, lead studies employ, achieve robust binding, explore ring size, critical independent variable, ring size, optimize binding, lead compound, traditional approaches, symmetry required, small molecule, rarely able, powerful strategy, medicinal chemistry, independent variable, hits lack, ent <

Relation: https://figshare.com/articles/journal_contribution/Ring_Size_as_an_Independent_Variable_in_Cyclooligomeric_Depsipeptide_Antiarrhythmic_Activity/17069760

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00508.s001

المؤلفون: Crystal M. Ripplinger, Alexey V. Glukhov, Matthew W. Kay, Bastiaan J. Boukens, Nipavan Chiamvimonvat, Brian P. Delisle, Larissa Fabritz, Thomas J. Hund, Bjorn C. Knollmann, Na Li, Katherine T. Murray, Steven Poelzing, T. Alexander Quinn, Carol Ann Remme, Stacey L. Rentschler, Robert A. Rose, Nikki G. Posnack

المصدر: American journal of physiology. Heart and circulatory physiology. 323(6):H1137-H1166

مصطلحات موضوعية: Physiology, ECG, small animals, Induced Pluripotent Stem Cells, Arrhythmias, Cardiac, arrhythmia, Cardiovascular Diseases, Physiology (medical), Animals, Humans, Myocytes, Cardiac, guidelines, Electrophysiologic Techniques, Cardiac, Cardiology and Cardiovascular Medicine, cardiac electrophysiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f634ea199ebedbe0ad732ee2517bfaf2
https://doi.org/10.1152/ajpheart.00439.2022

المؤلفون: Abigail N. Smith, Madelaine P. Thorpe, Daniel J. Blackwell, Suzanne M. Batiste, Corey R. Hopkins, Nathan D. Schley, Bjorn C. Knollmann, Jeffrey N. Johnston

المصدر: ACS Medicinal Chemistry Letters. 13:1755-1762

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0fc3e144be299f5130f430d9bee85ab0
https://doi.org/10.1021/acsmedchemlett.2c00377

المؤلفون: John A. Oates, Pierre P. Massion, Lawrence J. Marnett, Philip E. Lammers, Bjorn C. Knollmann, Megan Hoeksema, Bradford K. Harris, Ginger Milne, Brenda C. Crews, Hyun S. Hwang, David Adler, Denise Oram, Taneem Amin, I. Romina Sosa, Olivier Boutaud

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0ef6b76fa74c21e969ad45ff040932
https://doi.org/10.1158/1940-6207.22534747

المؤلفون: James P. Allison, Javid J. Moslehi, Justin M. Balko, Joe-Elie Salem, Padmanee Sharma, Lauren I.R. Ehrlich, Jing Wang, Yang Zhao, Xiayu Rao, Oluwatomisin T. Atolagbe, Yu Li, Jayashree Srinivasan, Bjorn C. Knollmann, Matthew J. Wleklinski, Benedicte Lebrun-Vignes, Lauren E. Himmel, James J. Mancuso, Pierre-Yves Courand, Lorenz Lehmann, Elizabeth Whitley, Douglas B. Johnson, Elizabeth C. Wescott, Elles M. Screever, Nana-Ama A.S. Anang, Margaret L. Axelrod, Wouter C. Meijers, Spencer C. Wei

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ac086af2e9029b3bb7219798b72ea281
https://doi.org/10.1158/2159-8290.c.6547996.v1