المؤلفون: Leist, Marcel, Ghallab, Ahmed, Graepel, Rabea, Marchan, Rosemarie, Hassan, Reham, Bennekou, Susanne Hougaard, Limonciel, Alice, Vinken, Mathieu, Schildknecht, Stefan, Waldmann, Tanja, Danen, Erik, van Ravenzwaay, Ben, Kamp, Hennicke, Gardner, Iain, Godoy, Patricio, Bois, Frederic Y., Braeuning, Albert, Reif, Raymond, Oesch, Franz, Drasdo, Dirk, Hoehme, Stefan, Schwarz, Michael, Hartung, Thomas, Braunbeck, Thomas, Beltman, Joost, Vrieling, Harry, Sanz, Ferran, Forsby, Anna, Gadaleta, Domenico, Fisher, Ciaran, Kelm, Jens, Fluri, David, Ecker, Gerhard, Zdrazil, Barbara, Terron, Andrea, Jennings, Paul, van der Burg, Bart, Dooley, Steven, Meijer, Annemarie H., Willighagen, Egon, Martens, Marvin, Evelo, Chris, Mombelli, Enrico, Taboureau, Olivier, Mantovani, Alberto, Hardy, Barry, Koch, Bjorn, Escher, Sylvia, van Thriel, Christoph, Cadenas, Cristina, Kroese, D., van de Water, Bob, Hengstler, Jan G.

المصدر: Leist , M , Ghallab , A , Graepel , R , Marchan , R , Hassan , R , Bennekou , S H , Limonciel , A , Vinken , M , Schildknecht , S , Waldmann , T , Danen , E , van Ravenzwaay , B , Kamp , H , Gardner , I , Godoy , P , Bois , F Y , Braeuning , A , Reif , R , Oesch , F , Drasdo , D , Hoehme , S , Schwarz , M , Hartung , T , Braunbeck , T , ....

مصطلحات موضوعية: Regulatory toxicology, Systems biology, Multi-scale integration, Computational toxicology, Interspecies extrapolation, Metabolism, Pathway unidirectionality, Liver fibrosis, Paracetamol, CCl4, Vinyl acetate, Tumor promotion, Binning of events, Multiple hit events Proof of non-toxicity, Prioritization of compounds, TUMOR-NECROSIS-FACTOR, EVIDENCE-BASED TOXICOLOGY, ACTIVATED STELLATE CELLS, NATURAL-KILLER-CELLS, DEVELOPMENTAL NEUROTOXICITY, RISK-ASSESSMENT, READ-ACROSS, ENVIRONMENTAL CHEMICALS, SYSTEMS TOXICOLOGY

وصف الملف: application/pdf

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/7bb2620a-5147-46d8-8a23-cd39eb2f2471
https://doi.org/10.1007/s00204-017-2045-3
https://cris.maastrichtuniversity.nl/ws/files/34655726/Willighagen_2017_Adverse_Outcome_Pathways.pdf

مصطلحات موضوعية: CCl4, Interspecies extrapolation, Proof of non-toxicity, Liver fibrosis, Multiple hit events, Binning of events, Multi-scale integration, Prioritization of compounds, Metabolism, Paracetamol, Vinyl acetate, Tumor promotion, Computational toxicology, Regulatory toxicology, Systems biology, Pathway unidirectionality

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______202::758f31e38a062edf3a5bf6488bb76326

المؤلفون: Leist, M., Ghallab, A., Graepel, R., Marchan, R., Hassan, R., Bennekou, S.H., Limonciel, A., Vinken, M., Schildknecht, S., Waldmann, T., Danen, E., Ravenzwaay, B. van, Kamp, H., Gardner, I., Godoy, P., Bois, F.Y., Braeuning, A., Reif, R., Oesch, F., Drasdo, D., Höhme, S., Schwarz, M., Hartung, T., Braunbeck, T., Beltman, J., Vrieling, H., Sanz, F., Forsby, A., Gadaleta, D., Fisher, C., Kelm, J., Fluri, D., Ecker, G., Zdrazil, B., Terron, A., Jennings, P., Burg, B. van der, Dooley, S., Meijer, A.H., Willighagen, E., Martens, M., Evelo, C., Mombelli, E., Taboureau, O., Mantovani, A., Hardy, B., Koch, B., Escher, S., van Thriel, C., Cadenas, C., Kroese, D., Water, B. van de, Hengstler, J.G.

المصدر: Archives of Toxicology, 11, 91, 3477-3505

مصطلحات موضوعية: Biology, Binning of events, CCl4, Computational toxicology, Interspecies extrapolation, Liver fibrosis, Metabolism, Multi-scale integration, Multiple hit events, Paracetamol, Pathway unidirectionality, Prioritization of compounds, Proof of non-toxicity, Regulatory toxicology, Systems biology, Tumor promotion, Vinyl acetate, Adverse outcome, Adverse outcome pathway, Ecotoxicology, Epidemiological data, Human, Nonhuman, Plasticity, Risk assessment, Signal transduction, Toxicity assay, Toxicokinetics, Biomedical Innovation, Healthy Living

Relation: uuid:12b5a0d9-939d-4bd0-9760-54b214f15cf1; 782466; http://resolver.tudelft.nl/uuid:12b5a0d9-939d-4bd0-9760-54b214f15cf1

الاتاحة: http://resolver.tudelft.nl/uuid:12b5a0d9-939d-4bd0-9760-54b214f15cf1

مصطلحات موضوعية: CCl4, Plasticity, Proof of non-toxicity, Liver fibrosis, RAPID - Risk Analysis for Products in Development, Biomedical Innovation, Multiple hit events, Signal transduction, Ecotoxicology, Binning of events, Adverse outcome, Prioritization of compounds, Adverse outcome pathway, Life, Tumor promotion, Life and Social Sciences, Regulatory toxicology, Biology, Risk assessment, Epidemiological data, Interspecies extrapolation, ELSS - Earth, Nonhuman, Toxicity assay, Toxicokinetics, Multi-scale integration, Metabolism, Paracetamol, Vinyl acetate, Computational toxicology, Systems biology, Healthy Living, Pathway unidirectionality, Human

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___00893::abed23dff0038089d24232bdd78ac103
http://resolver.tudelft.nl/uuid:12b5a0d9-939d-4bd0-9760-54b214f15cf1

المؤلفون: Leist, Marcel, Ghallab, Ahmed, Graepel, Rabea, Marchan, Rosemarie, Hassan, Reham, Hougaard Bennekou, Susanne, Limonciel, Alice, Vinken, Mathieu, Schildknecht, Stefan, Waldmann, Tanja, Danen, Erik, van Ravenzwaay, Ben, Kamp, Hennicke, Gardner, Iain, Godoy, Patricio, Bois, Frederic Y., Braeuning, Albert, Reif, Raymond, Oesch, Franz, Drasdo, Dirk, Höhme, Stefan, Schwarz, Michael, Hartung, Thomas, Braunbeck, Thomas, Beltman, Joost, Vrieling, Harry, Sanz, Ferran, Forsby, Anna, Gadaleta, Domenico, Fisher, Ciaran, Kelm, Jens, Fluri, David, Ecker, Gerhard, Zdrazil, Barbara, Terron, Andrea, Jennings, Paul, van der Burg, Bart, Dooley, Steven, Meijer, Annemarie H., Willighagen, Egon, Martens, Marvin, Evelo, Chris, Mombelli, Enrico, Taboureau, Olivier, Mantovani, Alberto, Hardy, Barry, Koch, Bjorn, Escher, Sylvia, van Thriel, Christoph, Cadenas, Cristina, Kroese, D., van de Water, Bob, Hengstler, Jan G.

مصطلحات الفهرس: Regulatory toxicology, Systems biology, Multi-scale integration, Computational toxicology, Interspecies extrapolation, Metabolism, Pathway unidirectionality, Liver fibrosis, Paracetamol, CCl4, Vinyl acetate, Tumor promotion, Binning of events, Multiple hit events Proof of non-toxicity, Prioritization of compounds, Biological Sciences, Biologiska vetenskaper, Pharmacology and Toxicology, Farmakologi och toxikologi, Article in journal, info:eu-repo/semantics/article, text

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-150001
Archives of Toxicology, 0340-5761, 2017, 91:11, s. 3477-3505