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المؤلفون: Shuang Liu, Bingqi Tong, Jeremy W. Mason, Jonathan M. Ostrem, Antonin Tutter, Bruce K. Hua, Sunny A. Tang, Simone Bonazzi, Karin Briner, Frédéric Berst, Frédéric J. Zécri, Stuart L. Schreiber
المصدر: bioRxiv
مصطلحات موضوعية: Article
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المؤلفون: Bingqi Tong, Thomas J. Maimone, Bridget P. Belcher, Daniel K. Nomura
المصدر: Chemical science, vol 12, iss 25
Chemical Scienceمصطلحات موضوعية: Natural product, Gymnascella, biology, 010405 organic chemistry, Stereochemistry, Growth inhibitory, General Chemistry, 010402 general chemistry, biology.organism_classification, 01 natural sciences, 0104 chemical sciences, chemistry.chemical_compound, Chemistry, chemistry, Biosynthesis, Covalent bond, Clinical Research, Electrophile, Breast Cancer, Chemical Sciences, Tyrosine, Cytotoxicity, Cancer
وصف الملف: application/pdf
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المؤلفون: Thomas J. Maimone, Jeffrey Mckenna, Jessica N. Spradlin, Yi Xie, John A. Tallarico, Mai Luo, Daniel K. Nomura, Markus Schirle, Bingqi Tong
المصدر: Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Ubiquitin-Protein Ligases, Chemical biology, lcsh:Medicine, Organic chemistry, Medicinal chemistry, Cell Cycle Proteins, Plasma protein binding, Protein degradation, 01 natural sciences, Article, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, Humans, Chemical synthesis, Oleanolic Acid, Bifunctional, lcsh:Science, Natural products, Multidisciplinary, Tumor, biology, 010405 organic chemistry, Drug discovery, lcsh:R, Small molecules, Ubiquitination, Azepines, Triazoles, Combinatorial chemistry, Small molecule, 0104 chemical sciences, Ubiquitin ligase, 030104 developmental biology, chemistry, Proteolysis, biology.protein, lcsh:Q, Bardoxolone, Chemical tools, Transcription Factors
وصف الملف: application/pdf
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المؤلفون: Jessica N. Spradlin, John A. Tallarico, Scott M. Brittain, Mai Luo, Lydia Boike, Bingqi Tong, Jeffrey Mckenna, Markus Schirle, Dan Nomura, Thomas J. Maimone
مصطلحات موضوعية: chemistry.chemical_compound, Natural product, chemistry, biology, Drug discovery, Chemical biology, biology.protein, Chemoproteomics, Computational biology, Protein degradation, Small molecule, Function (biology), Ubiquitin ligase
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المؤلفون: Luiz F. T. Novaes, Xirui Hu, Malte Moeller, Jessica N. Spradlin, Jeffrey Mckenna, Scott M. Brittain, Erika Zhang, Markus Schirle, Lynn M. McGregor, Bingqi Tong, Thomas J. Maimone, Daniel K. Nomura, John A. Tallarico
المصدر: ACS Chem Biol
مصطلحات موضوعية: 0301 basic medicine, Limonins, Ubiquitin-Protein Ligases, Fusion Proteins, bcr-abl, Protein degradation, 01 natural sciences, Biochemistry, Article, 03 medical and health sciences, chemistry.chemical_compound, hemic and lymphatic diseases, medicine, Humans, Protein Kinase Inhibitors, Natural product, biology, Oncogene, 010405 organic chemistry, Chemistry, Kinase, Cereblon, General Medicine, 0104 chemical sciences, Ubiquitin ligase, Cell biology, Dasatinib, Thiazoles, 030104 developmental biology, Cancer cell, Proteolysis, biology.protein, Molecular Medicine, K562 Cells, medicine.drug
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المؤلفون: Bingqi Tong, Daniel K. Nomura, Thomas J. Maimone, Erika Zhang, Lynn M. McGregor, Luiz F. T. Novaes, John A. Tallarico, Xirui Hu, Jessica N. Spradlin, Markus Schirle, Scott M. Brittain, Jeffrey Mckenna, Malte Moeller
مصطلحات موضوعية: BRD4, biology, Chemistry, Kinase, Cereblon, Protein degradation, Ubiquitin ligase, law.invention, Cell biology, Dasatinib, law, hemic and lymphatic diseases, Cancer cell, biology.protein, medicine, Suppressor, medicine.drug
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المؤلفون: Daniel Nomura, Thomas J. Maimone, Markus Schirle, Jeffrey M. McKenna, John A. Tallarico, Jessica Spradlin, Yi Xie, Mai Luo, Bingqi Tong
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المؤلفون: Thomas J. Maimone, Bingqi Tong
المصدر: Chem. 5:1368-1370
مصطلحات موضوعية: Chemistry, General Chemical Engineering, Terpene biosynthesis, Biochemistry (medical), 02 engineering and technology, General Chemistry, Carbocation, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Biochemistry, 0104 chemical sciences, Terpene, Materials Chemistry, Environmental Chemistry, Organic chemistry, 0210 nano-technology, Terpene synthesis
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المؤلفون: Joseph M. Hendricks, Breanna Ford, James A. Olzmann, Thomas J. Maimone, Roberto Zoncu, Zhipeng Li, Peter H. Tang, Bingqi Tong, Melissa A. Roberts, Leslie Magtanong, Daniel K. Nomura, Michael C. Bassik, Scott J. Dixon, Kirill Bersuker
المصدر: Nature, vol 575, iss 7784
مصطلحات موضوعية: 0301 basic medicine, Enzymologic, Male, Programmed cell death, Lipid Peroxides, Ubiquinone, General Science & Technology, GPX4, SCID, law.invention, Cell Line, Mitochondrial Proteins, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, law, 2.1 Biological and endogenous factors, Animals, Humans, Ferroptosis, Aetiology, AIFM2, Cancer, Coenzyme Q10, Multidisciplinary, Tumor, Chemistry, Cell Membrane, Glutathione, Phospholipid Hydroperoxide Glutathione Peroxidase, Cell biology, Good Health and Well Being, 030104 developmental biology, Gene Expression Regulation, 5.1 Pharmaceuticals, Cell culture, 030220 oncology & carcinogenesis, Cancer cell, Suppressor, Heterografts, Development of treatments and therapeutic interventions, Apoptosis Regulatory Proteins
وصف الملف: application/pdf
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المؤلفون: John A. Tallarico, Thomas J. Maimone, Markus Schirle, Daniel K. Nomura, Bingqi Tong, Mai Luo, Jeffrey Mckenna, Jessica N. Spradlin, Lydia Boike, Scott M. Brittain
المصدر: Cell Chem Biol
مصطلحات موضوعية: Proteomics, Ubiquitin-Protein Ligases, Clinical Biochemistry, Chemical biology, Computational biology, 01 natural sciences, Biochemistry, Article, chemistry.chemical_compound, Drug Discovery, Humans, Chemoproteomics, Molecular Biology, Pharmacology, Biological Products, Natural product, Molecular Structure, biology, 010405 organic chemistry, Drug discovery, Ubiquitination, 0104 chemical sciences, Ubiquitin ligase, chemistry, Covalent bond, biology.protein, Molecular Medicine, Identification (biology), Function (biology)
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المؤلفون: Kirill, Bersuker, Joseph M, Hendricks, Zhipeng, Li, Leslie, Magtanong, Breanna, Ford, Peter H, Tang, Melissa A, Roberts, Bingqi, Tong, Thomas J, Maimone, Roberto, Zoncu, Michael C, Bassik, Daniel K, Nomura, Scott J, Dixon, James A, Olzmann
المصدر: Nature. 575(7784)
مصطلحات موضوعية: Male, Lipid Peroxides, Ubiquinone, Cell Membrane, Mice, SCID, Phospholipid Hydroperoxide Glutathione Peroxidase, Gene Expression Regulation, Enzymologic, Mitochondrial Proteins, Mice, Cell Line, Tumor, Animals, Ferroptosis, Heterografts, Humans, Apoptosis Regulatory Proteins