المؤلفون: Zhang, Nina, Zheng, Weijia, Bakker, Wouter, van Ravenzwaay, Bennard, Rietjens, Ivonne M.C.M.

المصدر: Chemico-Biological Interactions 375 (2023) ; ISSN: 0009-2797

مصطلحات موضوعية: Bile acid transport, Caco-2 cells, Conjugated bile acids, Fecal incubation, Tobramycin

وصف الملف: application/pdf

Relation: https://edepot.wur.nl/590634

الاتاحة: https://research.wur.nl/en/publications/in-vitro-models-to-measure-effects-on-intestinal-deconjugation-an
https://doi.org/10.1016/j.cbi.2023.110445

المؤلفون: Wang, Jingxuan, Bakker, Wouter, de Haan, Laura, Bouwmeester, Hans

المصدر: Food Research International 173 (2023) ; ISSN: 0963-9969

مصطلحات موضوعية: Bile acid transport, Deoxynivalenol, In vitro co-cultures, Inflammation, Intestine, Primary bile acid

وصف الملف: application/pdf

Relation: https://edepot.wur.nl/636989

الاتاحة: https://research.wur.nl/en/publications/deoxynivalenol-increases-pro-inflammatory-cytokine-secretion-and-
https://doi.org/10.1016/j.foodres.2023.113323

المؤلفون: Chao Zheng Li, Hiromi Ogawa, Soon Seng Ng, Xindi Chen, Eriko Kishimoto, Kokoro Sakabe, Aiko Fukami, Yueh-Chiang Hu, Christopher N. Mayhew, Jennifer Hellmann, Alexander Miethke, Nahrin L. Tasnova, Samuel J.I. Blackford, Zu Ming Tang, Adam M. Syanda, Liang Ma, Fang Xiao, Melissa Sambrotta, Oliver Tavabie, Filipa Soares, Oliver Baker, Davide Danovi, Hisamitsu Hayashi, Richard J. Thompson, S. Tamir Rashid, Akihiro Asai

المصدر: JHEP Reports, Vol 4, Iss 4, Pp 100446- (2022)

مصطلحات موضوعية: PFIC (progressive familial intrahepatic cholestasis), Cellular polarity, Bile acid transport, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555922000180; https://doaj.org/toc/2589-5559

URL الوصول: https://doaj.org/article/a3897953261242379e6856ff67f6e514

المؤلفون: Massimo Palatini, Simon Franz Müller, Michael Kirstgen, Silke Leiting, Felix Lehmann, Lena Soppa, Nora Goldmann, Christin Müller, Kira Alessandra Alicia Theresa Lowjaga, Jörg Alber, Giuliano Ciarimboli, John Ziebuhr, Dieter Glebe, Joachim Geyer

المصدر: Viruses; Volume 14; Issue 4; Pages: 727

مصطلحات موضوعية: HBV, HDV, infection, NTCP, IFITM3, virus entry, entry inhibitor, protein–protein interaction, bile acid transport, preS1 peptide

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Viral Immunology, Vaccines, and Antivirals; https://dx.doi.org/10.3390/v14040727

الاتاحة: https://doi.org/10.3390/v14040727

المؤلفون: Dariusz Zakrzewicz, Joachim Geyer

المصدر: Biomedicines; Volume 10; Issue 1; Pages: 196

مصطلحات موضوعية: HBV, posttranslational modification, Na + /taurocholate cotransporting polypeptide, NTCP, mutation, bile acid transport, virus receptor

وصف الملف: application/pdf

Relation: Drug Discovery; https://dx.doi.org/10.3390/biomedicines10010196

الاتاحة: https://doi.org/10.3390/biomedicines10010196

المؤلفون: Massimo Palatini, Simon Franz Müller, Kira Alessandra Alicia Theresa Lowjaga, Saskia Noppes, Jörg Alber, Felix Lehmann, Nora Goldmann, Dieter Glebe, Joachim Geyer

المصدر: Frontiers in Molecular Biosciences, Vol 8 (2021)

مصطلحات موضوعية: Na+/taurocholate co-transporting polypeptide, bile acid transport, dimerization, sorting, protein-protein interaction, hepatitis B virus, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.699443/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/6c23159bd421475db423da40c2f18bae

المؤلفون: Arrese, M, Traumer, M, Ananthanarayanan, M, Pizarro, M, Solis, N, Accatino, L, Soroka, C, Boyer, JL, Karpen, SJ, Miquel, JF, Suchy, FJ

مصطلحات موضوعية: bile acid transport, transporters, Na+/taurocholate cotransporting polypeptide, SALT EXPORT PUMP, BILE-ACID, INTRAHEPATIC CHOLESTASIS, NUCLEAR RECEPTOR, TRANSPORT, LIVER, MECHANISMS, EXPRESSION, PROLACTIN, HEPATOCYTES, 03 Good Health and Well-being, 03 Salud y bienestar

وصف الملف: 8 páginas; application/pdf

Relation: MEDLINE:11804680; MEDLINE:12547402; https://doi.org/10.1016/S0168-8278(02)00379-3; https://repositorio.uc.cl/handle/11534/79297; WOS:000180892900003

الاتاحة: https://repositorio.uc.cl/handle/11534/79297
https://doi.org/10.1016/S0168-8278(02)00379-3

المؤلفون: Kirstgen, Michael, Müller, Simon Franz, Lowjaga, Kira Alessandra Alicia Theresa, Goldmann, Nora, Lehmann, Felix, Alakurtti, Sami, Yli-Kauhaluoma, Jari, Baringhaus, Karl-Heinz, Krieg, Reimar, Glebe, Dieter, Geyer, Joachim

المساهمون: Faculty of Pharmacy, Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Divisions of Faculty of Pharmacy, Pharmaceutical Design and Discovery group, Jari Yli-Kauhaluoma / Principal Investigator, Medicinal Chemistry research group

مصطلحات موضوعية: BETULIN, BILE-ACID TRANSPORT, CELLS, CYCLOSPORINE-A, DERIVATIVES, DISCOVERY, HBV, HDV, HEPATITIS-B-VIRUS, INFECTION, MEMBRANE TRANSPORTER, NTCP, QSAR, entry inhibitor, pharmacophore, virtual screen, Pharmacy, 11832 Microbiology and virology

وصف الملف: application/pdf

Relation: Funding: This study was supported by FlexFunds from the LOEWE-Center DRUID (Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases) and in part by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)—Projektnummer 197785619—SFB 1021 as well as by the Foundation for Research of Natural Resources in Finland, Marjatta ja Eino Kollin Säätiö, and the COST Action CM-0801 (New drugs for neglected diseases).; Kirstgen , M , Müller , S F , Lowjaga , K A A T , Goldmann , N , Lehmann , F , Alakurtti , S , Yli-Kauhaluoma , J , Baringhaus , K-H , Krieg , R , Glebe , D & Geyer , J 2021 , ' Identification of novel HBV/HDV entry inhibitors by pharmacophore- and QSAR-guided virtual screening ' , Viruses (Basel) , vol. 13 , no. 8 , 1489 . https://doi.org/10.3390/v13081489; ORCID: /0000-0003-0370-7653/work/98859835; http://hdl.handle.net/10138/333428; 689efe14-2d21-468b-847b-1d5945e5aa54; 000689866000001

الاتاحة: http://hdl.handle.net/10138/333428

المؤلفون: Michael Kirstgen, Kira Alessandra Alicia Theresa Lowjaga, Simon Franz Müller, Nora Goldmann, Felix Lehmann, Dieter Glebe, Karl-Heinz Baringhaus, Joachim Geyer

المصدر: Viruses; Volume 13; Issue 4; Pages: 666

مصطلحات موضوعية: HBV, HDV, NTCP, ASBT, bile acid transport, entry inhibitor, structure-activity relationship

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Animal Viruses; https://dx.doi.org/10.3390/v13040666

الاتاحة: https://doi.org/10.3390/v13040666

المؤلفون: Russell, Laura E

المصدر: Electronic Thesis and Dissertation Repository

مصطلحات موضوعية: NTCP, SLC10A1, bile acid transport, rosuvastatin, transporters, genetic variation, Medical Pharmacology

وصف الملف: application/pdf

Relation: https://ir.lib.uwo.ca/etd/7311; https://ir.lib.uwo.ca/context/etd/article/9757/viewcontent/Russell_Laura_PhD_Thesis__1_.pdf

الاتاحة: https://ir.lib.uwo.ca/etd/7311
https://ir.lib.uwo.ca/context/etd/article/9757/viewcontent/Russell_Laura_PhD_Thesis__1_.pdf

المؤلفون: Ruggiero, Melissa J., Malhotra, Shipra, Fenton, Aron W., Swint-Kruse, Liskin, Karanicolas, John, Hagenbuch, Bruno

مصطلحات موضوعية: Bile acid transport, Drug transport, Single nucleotide polymorphism, Hepatocyte, Liver, Protein stability

وصف الملف: application/pdf

Relation: Ruggiero, M. J., Malhotra, S., Fenton, A. W., Swint-Kruse, L., Karanicolas, J., & Hagenbuch, B. (2021). A clinically relevant polymorphism in the Na+/taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position. The Journal of biological chemistry, 296, 100047. https://doi.org/10.1074/jbc.RA120.014889; http://hdl.handle.net/1808/32357; https://orcid.org/ 0000-0002-2234-191X; https://orcid.org/ 0000-0001-8214-4785; https://orcid.org/ 0000-0002-5925-9741; https://orcid.org/ 0000-0003-0300-726X; https://orcid.org/ 0000-0002-2938-8630; PMC7948949

الاتاحة: http://hdl.handle.net/1808/32357
https://doi.org/10.1074/jbc.RA120.014889
https://orcid.org/ 0000-0002-2234-191X
https://orcid.org/ 0000-0001-8214-4785
https://orcid.org/ 0000-0002-5925-9741
https://orcid.org/ 0000-0003-0300-726X
https://orcid.org/ 0000-0002-2938-8630

المؤلفون: van de Peppel, Ivo P, Bertolini, Anna, van Dijk, Theo H, Groen, Albert K, Jonker, Johan W, Verkade, Henkjan J

المصدر: van de Peppel , I P , Bertolini , A , van Dijk , T H , Groen , A K , Jonker , J W & Verkade , H J 2019 , ' Efficient reabsorption of transintestinally excreted cholesterol is a strong determinant for cholesterol disposal in mice[S] ' , Journal of Lipid Research , vol. 60 , no. 9 , pp. 1562-1572 . https://doi.org/10.1194/jlr.M094607

مصطلحات موضوعية: ASBT inhibition, intestinal cholesterol absorption, transintestinal cholesterol excretion, ezetimibe, BILE-ACID TRANSPORT, LIVER-X-RECEPTOR, NEUTRAL STEROL EXCRETION, REDUCES ATHEROSCLEROSIS, PLASMA-CHOLESTEROL, ABSORPTION, METABOLISM, INHIBITION, MICE

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/fabe643b-ba46-4c13-9b93-fc735ff26263
https://research.rug.nl/en/publications/fabe643b-ba46-4c13-9b93-fc735ff26263
https://doi.org/10.1194/jlr.M094607
https://pure.rug.nl/ws/files/94519137/Efficient_reabsorption_of_transintestinally_excreted_cholesterol_is_a_strong_determinant_for_cholesterol_disposal_in_mice.pdf
https://pure.rug.nl/ws/files/97541265/Efficient_reabsorption_of_transintestinally_excreted.pdf

المؤلفون: Peng Wang, Yumo Song, Heju Zhong, Sen Lin, Xiaoling Zhang, Jian Li, Lianqiang Che, Bin Feng, Yan Lin, Shengyu Xu, Yong Zhuo, De Wu, Douglas G. Burrin, Zhengfeng Fang

المصدر: International Journal of Molecular Sciences; Volume 20; Issue 17; Pages: 4099

مصطلحات موضوعية: placenta, pregnancy, high-throughput RNA sequencing (RNA-Seq), bile acid transport, bile acid sulfation, long non-coding RNA (lncRNA)

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/ijms20174099

الاتاحة: https://doi.org/10.3390/ijms20174099

المؤلفون: Eller, Carla, Heydmann, Laura, Colpitts, Che, Verrier, Eloi, Schuster, Catherine, Baumert, Thomas, F.

المساهمون: Institut de Recherche sur les Maladies Virales et Hépatiques (IVH), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Génétique Animale et Biologie Intégrative (GABI), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, Interaction virus-hôte et maladies du foie

المصدر: ISSN: 1420-682X.

مصطلحات موضوعية: Liver cell biology, Bile acid transport, Anti-viral therapy, Hepatocytes, Host factor, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology

الاتاحة: https://hal.science/hal-02374180
https://hal.science/hal-02374180v1/document
https://hal.science/hal-02374180v1/file/islandora_85190.pdf
https://doi.org/10.1007/s00018-018-2892-y

المؤلفون: Alan F. Hofmann, Lee R. Hagey

المصدر: Journal of Lipid Research, Vol 55, Iss 8, Pp 1553-1595 (2014)

مصطلحات موضوعية: bile acid transport, enterohepatic circulation, bile acid physical chemistry, bile acid analysis, bile acid metabolism, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520353232; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/71574a5f9f2d477290ec5736da47ae67

المؤلفون: Eitaro Aihara, Ayumu Mizutani, Nakayuki Naritaka, Hiroyuki Kusuhara, Yusuke Sabu, Aiko Fukami, Kenneth D. R. Setchell, Christopher N. Mayhew, Takanori Takebe, Akihiro Asai, Shuhei Osaka, Hisamitsu Hayashi, Masahide Sakabe, Kokoro Sakabe, Takahisa Nakamura, Eriko Kishimoto, Yueh Chiang Hu, Wujuan Zhang, Stacey S. Huppert

المصدر: Stem Cell Reports

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Induced Pluripotent Stem Cells, Cell Culture Techniques, Biology, Models, Biological, digestive system, Biochemistry, Article, PFIC2, Bile Acids and Salts, 03 medical and health sciences, 0302 clinical medicine, Cholestasis, hepatic differentiation, bile acid transport, Genetics, medicine, Humans, CRISPR genome editing, Induced pluripotent stem cell, ATP Binding Cassette Transporter, Subfamily B, Member 11, Cells, Cultured, Gene Editing, iPSC, Bile acid, Progressive familial intrahepatic cholestasis, Biological Transport, Cell Differentiation, Cell Biology, medicine.disease, Bile Salt Export Pump, Cell biology, 030104 developmental biology, bile acid synthesis, Paracellular transport, Mutation, Hepatocytes, progressive familial intrahepatic cholestasis, CRISPR-Cas Systems, Stem cell, 030217 neurology & neurosurgery, Intracellular, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70ab469ffecf140b481001d135e4c59
https://doi.org/10.1016/j.stemcr.2020.12.008

المؤلفون: Carol J. Potter

المصدر: Clinics in Perinatology. 47:341-354

مصطلحات موضوعية: Cholestasis, Bile acid transport, Bile acid, business.industry, medicine.drug_class, Infant, Newborn, Infant, Obstetrics and Gynecology, Physiology, Comorbidity, medicine.disease, 03 medical and health sciences, Liver disease, 0302 clinical medicine, 030225 pediatrics, Pediatrics, Perinatology and Child Health, Humans, Medicine, 030212 general & internal medicine, Liver dysfunction, business, Infant, Premature, Organ system

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7001c354df9eb8be9c09e7970ff591
https://doi.org/10.1016/j.clp.2020.02.009

المؤلفون: Joachim Geyer, Dariusz Zakrzewicz

المصدر: Biomedicines, Vol 10, Iss 196, p 196 (2022)

مصطلحات موضوعية: posttranslational modification, QH301-705.5, Na+/taurocholate cotransporting polypeptide, bile acid transport, HBV, Medicine (miscellaneous), virus diseases, NTCP, mutation, Biology (General), digestive system, General Biochemistry, Genetics and Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbed313460b412c04a5c8f16ce137cb2
https://www.mdpi.com/2227-9059/10/1/196

المؤلفون: Dariusz, Zakrzewicz, Joachim, Geyer

المصدر: Biomedicines

مصطلحات موضوعية: posttranslational modification, Na+/taurocholate cotransporting polypeptide, bile acid transport, HBV, virus diseases, Review, NTCP, mutation, digestive system, virus receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::170884e7e759e6c8def423079ae4c42c
https://pubmed.ncbi.nlm.nih.gov/35052874

المؤلفون: Alan F Hofmann

المصدر: Annals of Hepatology, Vol 6, Iss 1, Pp 15-27 (2007)

مصطلحات موضوعية: Bile acids, bile salts, bile acid metabolism, bile acid transport, biliary disease, Specialties of internal medicine, RC581-951

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1665268119319490; https://doaj.org/toc/1665-2681

URL الوصول: https://doaj.org/article/112ba7a69ef74a92a26d069d98133a32