المؤلفون: Xuanwen Li, Nicholas A. Pierson, Xiaoqing Hua, Bhumit A. Patel, Michael H. Olma, Christopher A. Strulson, Simon Letarte, Douglas D. Richardson

المصدر: Journal of Pharmaceutical Sciences. 112:691-699

مصطلحات موضوعية: Pharmaceutical Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeeeee50a41e438f26f936b62c5de9b0
https://doi.org/10.1016/j.xphs.2022.10.018

المؤلفون: Trina Mouchahoir (10297597), John E. Schiel (2136505), Rich Rogers (10297600), Alan Heckert (4635451), Benjamin J. Place (10150941), Aaron Ammerman (10297603), Xiaoxiao Li (195315), Tom Robinson (1727026), Brian Schmidt (95162), Chris M. Chumsae (10297606), Xinbi Li (1342749), Anton V. Manuilov (10297609), Bo Yan (57900), Gregory O. Staples (131773), Da Ren (1319568), Alexander J. Veach (10297612), Dongdong Wang (742338), Wael Yared (116319), Zoran Sosic (2944137), Yan Wang (15435), Li Zang (288884), Anthony M. Leone (2006899), Peiran Liu (10297615), Richard Ludwig (1405198), Li Tao (154250), Wei Wu (27708), Ahmet Cansizoglu (10297618), Andrew Hanneman (10297621), Greg W. Adams (10297624), Irina Perdivara (589451), Hunter Walker (10297627), Margo Wilson (10140803), Arnd Brandenburg (10297630), Nick DeGraan-Weber (4782732), Stefano Gotta (10297633), Joe Shambaugh (10297636), Melissa Alvarez (10297639), X. Christopher Yu (1505734), Li Cao (106383), Chun Shao (1338009), Andrew Mahan (2448013), Hirsh Nanda (1544119), Kristen Nields (10297642), Nancy Nightlinger (10297645), Helena Maria Barysz (10297648), Michael Jahn (1790740), Ben Niu (1566001), Jihong Wang (2077267), Gabriella Leo (2223067), Nunzio Sepe (4183000), Yan-Hui Liu (203243), Bhumit A. Patel (10297651), Douglas Richardson (2852555), Yi Wang (32470), Daniela Tizabi (10297654), Oleg V. Borisov (1584487), Yali Lu (2405899), Ernest L. Maynard (742869), Albrecht Gruhler (10297657), Kim F. Haselmann (1413535), Thomas N. Krogh (10297660), Carsten P. Sönksen (10297663), Simon Letarte (9575537), Sean Shen (10297666), Kristin Boggio (4533613), Keith Johnson (2114893), Wenqin Ni (1979356), Himakshi Patel (10297669), David Ripley (4468378), Jason C. Rouse (1961689), Ying Zhang (40767), Carly Daniels (10297672), Andrew Dawdy (10297675), Olga Friese (4840983), Thomas W. Powers (10297678), Justin B. Sperry (2159275), Josh Woods (10297681), Eric Carlson (3928799), K. Ilker Sen (2311798), St John Skilton (10297684), Michelle Busch (1831714), Anders Lund (744740), Martha Stapels (10297687), Xu Guo (174019), Sibylle Heidelberger (2113363), Harini Kaluarachchi (1917634), Sean McCarthy (4855378), John Kim (40209), Jing Zhen (1317909), Ying Zhou (25031), Sarah Rogstad (6719483), Xiaoshi Wang (2056393), Jing Fang (170284), Weibin Chen (1505503), Ying Qing Yu (1861906), John G. Hoogerheide (10297690), Rebecca Scott (2928189), Hua Yuan (127582)

مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Cancer, Science Policy, Space Science, Biological Sciences not elsewhere classified, NPD parameters, Successful implementation, MS performance capabilities, NPD interlaboratory study, purity-indicating assay, MAM platform, Certain elements, Multi-Attribute Method, purity function, product life cycles, laboratories show, peak detection, manufacturer-specific protein, share experiences, MAM Consortium, NISTmAb Reference Material 8671. Re., New Peak Detection Performance Metrics, MAM Consortium Interlaboratory Study

Relation: https://figshare.com/articles/journal_contribution/New_Peak_Detection_Performance_Metrics_from_the_MAM_Consortium_Interlaboratory_Study/14210629

الاتاحة: https://doi.org/10.1021/jasms.0c00415.s005

المؤلفون: Trina Mouchahoir, John E. Schiel, Rich Rogers, Alan Heckert, Benjamin J. Place, Aaron Ammerman, Xiaoxiao Li, Tom Robinson, Brian Schmidt, Chris M. Chumsae, Xinbi Li, Anton V. Manuilov, Bo Yan, Gregory O. Staples, Da Ren, Alexander J. Veach, Dongdong Wang, Wael Yared, Zoran Sosic, Yan Wang, Li Zang, Anthony M. Leone, Peiran Liu, Richard Ludwig, Li Tao, Wei Wu, Ahmet Cansizoglu, Andrew Hanneman, Greg W. Adams, Irina Perdivara, Hunter Walker, Margo Wilson, Arnd Brandenburg, Nick DeGraan-Weber, Stefano Gotta, Joe Shambaugh, Melissa Alvarez, X. Christopher Yu, Li Cao, Chun Shao, Andrew Mahan, Hirsh Nanda, Kristen Nields, Nancy Nightlinger, Ben Niu, Jihong Wang, Wei Xu, Gabriella Leo, Nunzio Sepe, Yan-Hui Liu, Bhumit A. Patel, Douglas Richardson, Yi Wang, Daniela Tizabi, Oleg V. Borisov, Yali Lu, Ernest L. Maynard, Albrecht Gruhler, Kim F. Haselmann, Thomas N. Krogh, Carsten P. Sönksen, Simon Letarte, Sean Shen, Kristin Boggio, Keith Johnson, Wenqin Ni, Himakshi Patel, David Ripley, Jason C. Rouse, Ying Zhang, Carly Daniels, Andrew Dawdy, Olga Friese, Thomas W. Powers, Justin B. Sperry, Josh Woods, Eric Carlson, K. Ilker Sen, St John Skilton, Michelle Busch, Anders Lund, Martha Stapels, Xu Guo, Sibylle Heidelberger, Harini Kaluarachchi, Sean McCarthy, John Kim, Jing Zhen, Ying Zhou, Sarah Rogstad, Xiaoshi Wang, Jing Fang, Weibin Chen, Ying Qing Yu, John G. Hoogerheide, Rebecca Scott, Hua Yuan

المصدر: Journal of the American Society for Mass Spectrometry. 33:1659-1677

مصطلحات موضوعية: Quality Control, Benchmarking, Structural Biology, Proteins, Peptide Mapping, Mass Spectrometry, Spectroscopy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbb68de4c53ee4678b9e74066d51588
https://doi.org/10.1021/jasms.2c00129

المؤلفون: Dhanuka P. Wasalathanthri, Bhumit A. Patel

المصدر: Continuous Pharmaceutical Processing and Process Analytical Technology ISBN: 9781003149835

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::70c5e9a53126e3ae101fcd1d5b5f7ca2
https://doi.org/10.1201/9781003149835-14

المؤلفون: Irina Perdivara, Ben Niu, Kim F. Haselmann, St John Skilton, Anthony Leone, Gregory O. Staples, Carsten P. Sønksen, Helena Maria Barysz, Andrew Hanneman, Chun Shao, Rebecca Scott, Anders Lund, Carly Daniels, Michael Jahn, Da Ren, Nunzio Sepe, K. Ilker Sen, Zoran Sosic, David Ripley, Jing Zhen, Margo Wilson, Melissa Alvarez, John G Hoogerheide, Xinbi Li, Harini Kaluarachchi, Josh Woods, Wenqin Ni, Albrecht Gruhler, Keith A. Johnson, Arnd Brandenburg, Kristen Nields, Michelle Busch, Douglas D. Richardson, Yan Wang, Ahmet Cansizoglu, Xiaoxiao Li, Greg W Adams, Simon Letarte, Joe Shambaugh, Hua Yuan, Trina Mouchahoir, Tom Robinson, Xiaoshi Wang, Nancy S. Nightlinger, Alexander Julian Veach, Chris Chumsae, Eric Carlson, Dongdong Wang, Sean Shen, Jing Fang, Wei Wu, Stefano Gotta, Justin B. Sperry, Hirsh Nanda, X. Christopher Yu, Sibylle Heidelberger, Bhumit A. Patel, Jihong Wang, Sean McCarthy, Himakshi Patel, Thomas N. Krogh, Hunter Walker, Olga V. Friese, Daniela Tizabi, Yali Lu, Kristin Boggio, Ernest L. Maynard, Rich Rogers, Ying Zhou, Nick DeGraan-Weber, John E. Schiel, Weibin Chen, Jason C. Rouse, Li Tao, Thomas W. Powers, John Kim, Xu Guo, Bo Yan, Gabriella Leo, Ying Zhang, Oleg V. Borisov, Ying Qing Yu, Martha Stapels, Wael Yared, Yan-Hui Liu, Alan Heckert, Sarah Rogstad, Li Zang, Aaron Ammerman, Li Cao, Benjamin J. Place, Richard Ludwig, Anton V. Manuilov, Andrew Mahan, Andrew Dawdy, Yi Wang, Brian Schmidt, Peiran Liu

المصدر: Journal of the American Society for Mass Spectrometry. 32:913-928

مصطلحات موضوعية: business.industry, Chemistry, Process (engineering), media_common.quotation_subject, 010401 analytical chemistry, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, Peak detection, Structural Biology, Process engineering, business, Function (engineering), Spectroscopy, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baf4a0ab2df01bdb011465e0f168239
https://doi.org/10.1021/jasms.0c00415

المؤلفون: Xuanwen Li, Nicholas A. Pierson, Xiaoqing Hua, Bhumit A. Patel, Michael H. Olma, Christopher A. Strulson, Simon Letarte, Douglas D. Richardson

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::41b8c5b8cc24a26e2e9271085bbd3f93
https://doi.org/10.1101/2022.05.01.490194

المؤلفون: Shruti Patel, Julius Lagliva, Brooke Czapkowski, Xin Jin, Bhumit A. Patel, Verl Sriskanda, Alan Arbuckle, Eric Bortell, Pegg Jodi Ann, Durgesh V. Nadkarni, Leo Letendre, Debra M. Meyer, Heyi Li, Thomas F. Lerch, Deanna Di Grandi, Elizabeth Thomas, Qingping Jiang

المصدر: ACS Omega, Vol 4, Iss 4, Pp 6468-6475 (2019)

مصطلحات موضوعية: High molecular mass, Gemtuzumab ozogamicin, General Chemical Engineering, General Chemistry, Protein aggregation, Combinatorial chemistry, Characterization (materials science), lcsh:Chemistry, chemistry.chemical_compound, lcsh:QD1-999, chemistry, Calicheamicin, medicine, Drug product, medicine.drug, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e00ab32f41301c494eb6af23ae1b86d
https://doi.org/10.1021/acsomega.8b03627

المؤلفون: Nuno D.S. Pinto, Edita Botonjic-Sehic, Adrian Gospodarek, Bhumit A. Patel, Alejandro de Janon Gutiérrez, Steven A. Harris, Mark Brower, Jayesh Desai

مصطلحات موضوعية: Downstream (manufacturing), Chemistry, Biophysics, Biomanufacturing, Line (text file), Refractive index, Protein concentration

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::39db93c5e1451e021a69dcc09e4739c9
https://doi.org/10.1002/btpr.3187/v2/response1

المؤلفون: Alejandro de Janon Gutiérrez, Jayesh Desai, Mark Brower, Bhumit A. Patel, Nuno D.S. Pinto, Edita Botonjic-Sehic, Adrian Gospodarek, Steven A. Harris

المصدر: Biotechnology progressREFERENCES. 37(5)

مصطلحات موضوعية: Detection limit, Chromatography, Dynamic range, business.industry, Process analytical technology, Ultrafiltration, Antibodies, Monoclonal, CHO Cells, Recombinant Proteins, Refractometry, Bioreactors, Cricetulus, Downstream (manufacturing), Cricetinae, Batch processing, Environmental science, Animals, Humans, Biomanufacturing, Bioprocess, Process engineering, business, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cca6db7dc57d7e47039870879056d1
https://pubmed.ncbi.nlm.nih.gov/34164947

المؤلفون: Michael Larkin, Mark Brower, Mark Haverick, Adrian Gospodarek, Sophia A. Kenrick, Nihal Tugcu, Bhumit A. Patel, Douglas D. Richardson

المصدر: mAbs

مصطلحات موضوعية: Materials science, Process analytical technology, Short Communication, Immunology, Multiangle light scattering, 02 engineering and technology, process control, 01 natural sciences, Protein Aggregation, Pathological, Light scattering, Chemistry Techniques, Analytical, MALS, Dynamic light scattering, Immunology and Allergy, Process control, Animals, Humans, Biological Products, Chromatography, Molar mass, Hydrophilic interaction chromatography, 010401 analytical chemistry, Detector, aggregation, Antibodies, Monoclonal, 021001 nanoscience & nanotechnology, Dynamic Light Scattering, 0104 chemical sciences, Biological Therapy, Molecular Weight, 0210 nano-technology, PAT

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0364499d6c1c9ffb4816efe0de54b9ea
http://europepmc.org/articles/PMC6204791

المؤلفون: R. Kenneth Marcus, Douglas D. Richardson, Edward D. Hoegg, William N. Napoli, Bhumit A. Patel

المصدر: Journal of Analytical Atomic Spectrometry. 33:2015-2020

مصطلحات موضوعية: 0301 basic medicine, Glow discharge, Materials science, Atmospheric pressure, Electrospray ionization, 010401 analytical chemistry, Analytical chemistry, Mass spectrometry, 01 natural sciences, Ion source, 0104 chemical sciences, Analytical Chemistry, 03 medical and health sciences, 030104 developmental biology, Elemental analysis, Inductively coupled plasma, Quadrupole mass analyzer, Spectroscopy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e6fdd5c6c91359a3fe755cc4e709fdee
https://doi.org/10.1039/c8ja00278a

المؤلفون: Mark Brower, David Pollard, Nuno D.S. Pinto, Bruce Kilgore, Douglas D. Richardson, Jun H. Heo, Adrian Gospodarek, William N. Napoli, Bhumit A. Patel, Jayesh Desai, Daisy Richardson, Kudrat Goswami, Dominick Panzera

المصدر: Analytical chemistry. 89(21)

مصطلحات موضوعية: 0301 basic medicine, Process analytical technology, Ion chromatography, Analytical chemistry, CHO Cells, Buffers, 01 natural sciences, Continuous production, Analytical Chemistry, 03 medical and health sciences, Bioreactors, Cricetulus, Animals, Biomanufacturing, Bioprocess, Chromatography, Ion exchange, Chemistry, 010401 analytical chemistry, Antibodies, Monoclonal, Hydrogen-Ion Concentration, Chromatography, Ion Exchange, 0104 chemical sciences, 030104 developmental biology, Forced degradation, Critical quality attributes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ce9f4d994d680d69a021fea2ec61d3
https://pubmed.ncbi.nlm.nih.gov/28981255

المؤلفون: Doron C. Greenbaum, Todd E. Golde, Jaime Ballard, Bhumit A. Patel, Thierry T. Diagana, A. Taylor Bright, Frantisek Supek, Elizabeth A. Winzeler, Michael B. Harbut, Case W. McNamara, Bryan K. S. Yeung

المصدر: Proceedings of the National Academy of Sciences. 109:21486-21491

مصطلحات موضوعية: Proteome, Trypanosoma cruzi, medicine.medical_treatment, Molecular Sequence Data, Plasmodium falciparum, Drug Resistance, Endoplasmic-reticulum-associated protein degradation, Microbiology, Small Molecule Libraries, Ubiquitin, parasitic diseases, medicine, Animals, Aspartic Acid Endopeptidases, Humans, ERAD pathway, Parasites, Protease Inhibitors, Life Cycle Stages, Multidisciplinary, Protease, Antiparasitic Agents, Base Sequence, biology, Endoplasmic reticulum, Computational Biology, Endoplasmic Reticulum-Associated Degradation, Hep G2 Cells, Biological Sciences, Endoplasmic Reticulum Stress, biology.organism_classification, Antiparasitic agent, Liver, Biochemistry, Drug Design, Proteolysis, biology.protein, Proteasome Inhibitors, Toxoplasma, Signal peptide peptidase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951e600982fe2f6387f5d06dc653920d
https://doi.org/10.1073/pnas.1216016110

المؤلفون: Bhumit A. Patel, Yuejin Hua, Huan Chen, Brian R. Crane, Longfei Yin, Joanne Widom, Magali Moreau

المصدر: Proceedings of the National Academy of Sciences. 106:18183-18188

مصطلحات موضوعية: Ultraviolet Rays, Nitric Oxide, Gene Expression Regulation, Enzymologic, Nitric oxide, chemistry.chemical_compound, Downregulation and upregulation, Transcriptional regulation, Deinococcus, Monomeric GTP-Binding Proteins, chemistry.chemical_classification, Regulation of gene expression, Reactive oxygen species, Microbial Viability, Multidisciplinary, biology, Deinococcus radiodurans, Biological Sciences, biology.organism_classification, Up-Regulation, Cell biology, Nitric oxide synthase, Biochemistry, chemistry, biology.protein, Nitric Oxide Synthase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c52a3f03df568598ce4f4654440c26
https://doi.org/10.1073/pnas.0907262106

المؤلفون: Bhumit A. Patel, Gregory L. Challis, Philip R. Aston, Evan G. Johnson, Brian R. Crane, Johan A. Kers, Rosemary Loria, Donna M. Gibson, Stuart B. Krasnoff, Sarah M. Barry, Lijiang Song

المصدر: Nature chemical biology

مصطلحات موضوعية: Indoles, Nitric Oxide, 010402 general chemistry, 01 natural sciences, Streptomyces, Piperazines, Article, 03 medical and health sciences, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Biosynthesis, Nonribosomal peptide, Nitration, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Tryptophan, Cell Biology, Phytotoxin, Plants, biology.organism_classification, 0104 chemical sciences, 3. Good health, Amino acid, Biochemistry, chemistry, Biocatalysis, Nitro

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587177c267464ff224ae5252519154b6
https://doi.org/10.1038/nchembio.1048

المؤلفون: Vipul D. Prajapati, Anita M. Chaudhari, Abhishek K. Gandhi, Krishna Kumar Patel, Girish K. Jani, Bhumit N. Patel

المصدر: International journal of biological macromolecules. 73

مصطلحات موضوعية: Alginates, Ovalbumin, Polymers, Diffusion, Sodium, Chemistry, Pharmaceutical, chemistry.chemical_element, Oxcarbazepine, Bead, Biochemistry, Drug Delivery Systems, Glucuronic Acid, X-Ray Diffraction, Structural Biology, Spectroscopy, Fourier Transform Infrared, medicine, Interpenetrating polymer network, Fourier transform infrared spectroscopy, Particle Size, Molecular Biology, chemistry.chemical_classification, Analysis of Variance, Drug Carriers, Chromatography, Chemistry, Hexuronic Acids, General Medicine, Polymer, Factorial experiment, Microspheres, Drug Liberation, Kinetics, Carbamazepine, Chemical engineering, visual_art, visual_art.visual_art_medium, Swelling, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2086f1b24d63ebf52e826181b3cb62
https://pubmed.ncbi.nlm.nih.gov/25449123

المؤلفون: Brian R. Crane, Bhumit A. Patel

المصدر: Journal of Molecular Cell Biology. 2:234-236

مصطلحات موضوعية: chemistry.chemical_classification, Bacilli, Reactive oxygen species, Bacteria, biology, medicine.drug_class, Antibiotics, Cell Biology, General Medicine, biology.organism_classification, Anti-Bacterial Agents, Microbiology, Nitric oxide, Oxidative damage, chemistry.chemical_compound, Enzyme, Bacterial Proteins, chemistry, Biochemistry, Genetics, medicine, Nitric Oxide Synthase, Reactive Oxygen Species, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125453f4e69bfcb9099fbaab96978388
https://doi.org/10.1093/jmcb/mjp044

المؤلفون: Girish K. Jani, Bhumit N. Patel, Pankaj M. Maheriya, Vipul D. Prajapati, Prasant D. Patil

المصدر: International journal of biological macromolecules. 65

مصطلحات موضوعية: food.ingredient, Biochemistry, Lepidium sativum, Plant Mucilage, food, Structural Biology, Botany, Animals, Humans, Molecular Biology, Allelopathy, chemistry.chemical_classification, biology, food and beverages, Glycoside, Plant based, Brassicaceae, General Medicine, biology.organism_classification, chemistry, Mucilage, Phytochemical, Herb, Seeds, Safety

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9e483b1aa701966bf4f6e2e49be522
https://pubmed.ncbi.nlm.nih.gov/24418343

المؤلفون: Jawahar Sudhamsu, Bhumit A. Patel, Brian R. Crane

المصدر: Annual review of biochemistry. 79

مصطلحات موضوعية: chemistry.chemical_classification, Bacteria, Microbial metabolism, Bacterial enzymes, Biology, medicine.disease_cause, Arginine, Biochemistry, Redox, Cofactor, Nitric oxide, Heme oxygenase, chemistry.chemical_compound, chemistry, Metalloprotein, medicine, biology.protein, Animals, Nitrogen Oxides, Nitric Oxide Synthase, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e27d82b5596af131f974525e8f474b9
https://pubmed.ncbi.nlm.nih.gov/20370423

المؤلفون: Dennis L. Rousseau, Syun Ru Yeh, Mariam Kabir, Brian R. Crane, Jawahar Sudhamsu, Bhumit A. Patel, Michael V. Airola

مصطلحات موضوعية: Hemeproteins, Hemeprotein, Heme binding, Recombinant Fusion Proteins, Heme, medicine.disease_cause, Spectrum Analysis, Raman, Article, chemistry.chemical_compound, Bacterial Proteins, Cytochrome P-450 Enzyme System, medicine, Escherichia coli, Histidine, biology, Spectrum Analysis, Ferrochelatase, Porphyrin, chemistry, Biochemistry, biology.protein, Electrophoresis, Polyacrylamide Gel, Nitric Oxide Synthase, Carrier Proteins, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ab214fca4916fb3dce8f67253504f4
https://europepmc.org/articles/PMC2875318/