المؤلفون: Chang, Long-Sheng, Oblinger, Janet L., Smith, Abbi E., Ferrer, Marc, Angus, Steven P., Hawley, Eric, Petrilli, Alejandra M., Beauchamp, Roberta L., Riecken, Lars Björn, Erdin, Serkan, Poi, Ming, Huang, Jie, Bessler, Waylan K., Zhang, Xiaohu, Guha, Rajarshi, Thomas, Craig, Burns, Sarah S., Gilbert, Thomas S.K., Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Dixon, Shelley A.H., Masters, Andrea, Jones, David R., Yates, Charles W., Haggarty, Stephen J., La Rosa, Salvatore, Welling, D. Bradley, Stemmer-Rachamimov, Anat O., Plotkin, Scott R., Gusella, James F., Guinney, Justin, Morrison, Helen, Ramesh, Vijaya, Fernandez-Valle, Cristina, Johnson, Gary L., Blakeley, Jaishri O., Clapp, D. Wade

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Meningeal neoplasms, Neurilemmoma, Neurofibromin 2, Organophosphorus compounds, Pyrimidines

وصف الملف: application/pdf

Relation: PLOS ONE; Chang LS, Oblinger JL, Smith AE, et al. Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK. PLoS One. 2021;16(7):e0252048. Published 2021 Jul 15. doi:10.1371/journal.pone.0252048; https://hdl.handle.net/1805/31096

الاتاحة: https://hdl.handle.net/1805/31096

المؤلفون: Laurent, Danny, Smith, Abbi E., Bessler, Waylan K., Mendonca, Marc, Chin-Sinex, Helen, Descovich, Martina, Horvai, Andrew E., Clapp, D. Wade, Nakamura, Jean L.

المساهمون: Radiation Oncology, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Heterozygosity, Malignant transformation, Neurofibromatosis I, Plexiform neurofibromas, Radiation

وصف الملف: application/pdf

Relation: Neuro-Oncology Advances; Laurent D, Smith AE, Bessler WK, et al. Irradiation of Nf1 mutant mouse models of spinal plexiform neurofibromas drives pathologic progression and decreases survival. Neurooncol Adv. 2021;3(1):vdab063. Published 2021 Apr 23. doi:10.1093/noajnl/vdab063; https://hdl.handle.net/1805/30754

الاتاحة: https://hdl.handle.net/1805/30754

المؤلفون: Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D. Wade

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: GTPase-activating protein (GAP), Ras-related C3 botulinum toxin substrate 1 (Rac1), Schwann cells, Animal model, Kinase signaling, Neurofibromatosis type 1, Short hairpin RNA (shRNA), Tumor cell biology, Tumor suppressor

وصف الملف: application/pdf

Relation: Journal of Biological Chemistry; Mund JA, Park S, Smith AE, et al. Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1 [published correction appears in J Biol Chem. 2020 Nov 13;295(46):15795]. J Biol Chem. 2020;295(29):9948-9958. doi:10.1074/jbc.RA119.010981; https://hdl.handle.net/1805/31178

الاتاحة: https://hdl.handle.net/1805/31178

المؤلفون: Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D.Wade

المصدر: Journal of Biological Chemistry ; volume 295, issue 46, page 15795 ; ISSN 0021-9258

الاتاحة: https://doi.org/10.1074/jbc.aac120.016426
https://api.elsevier.com/content/article/PII:S0021925817504068?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925817504068?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.AAC120.016426

المؤلفون: Bessler, Waylan K., Kim, Grace, Hudson, Farlyn Z., Mund, Julie A., Mali, Raghuveer, Menon, Keshav, Kapur, Reuben, Clapp, D. Wade, Ingram, David A., Stansfield, Brian K.

المساهمون: Department of Defense, American Heart Association, Department of Pediatrics at Augusta University, National Institutes of Health

المصدر: Human Molecular Genetics ; volume 25, issue 6, page 1129-1139 ; ISSN 0964-6906 1460-2083

الاتاحة: http://dx.doi.org/10.1093/hmg/ddv635
http://academic.oup.com/hmg/article-pdf/25/6/1129/7148409/ddv635.pdf

المؤلفون: Bessler, Waylan K., Hudson, Farlyn Z., Zhang, Hanfang, Harris, Valerie, Wang, Yusi, Mund, Julie A., Downing, Brandon, Ingram, David A., Case, Jamie, Fulton, David J., Stansfield, Brian K.

المساهمون: Department of Defense, American Heart Association, Department of Pediatrics at Augusta University, National Institutes of Health

المصدر: Free Radical Biology and Medicine ; volume 97, page 212-222 ; ISSN 0891-5849

الاتاحة: http://dx.doi.org/10.1016/j.freeradbiomed.2016.06.002
https://api.elsevier.com/content/article/PII:S0891584916302891?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0891584916302891?httpAccept=text/plain

المؤلفون: Fisher, Michael J., Shih, Chie-Schin, Rhodes, Steven D., Armstrong, Amy E., Wolters, Pamela L., Dombi, Eva, Zhang, Chi, Angus, Steven P., Johnson, Gary L., Packer, Roger J., Allen, Jeffrey C., Ullrich, Nicole J., Goldman, Stewart, Gutmann, David H., Plotkin, Scott R., Rosser, Tena, Robertson, Kent A., Widemann, Brigitte C., Smith, Abbi E., Bessler, Waylan K., He, Yongzheng, Park, Su-Jung, Mund, Julie A., Jiang, Li, Bijangi-Vishehsaraei, Khadijeh, Robinson, Coretta Thomas, Cutter, Gary R., Korf, Bruce R., Blakeley, Jaishri O., Clapp, D. Wade

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Plexiform, Neurofibroma, Neurofibromatosis, Cabozantinib

وصف الملف: application/pdf

Relation: Nature Medicine; Fisher MJ, Shih CS, Rhodes SD, et al. Cabozantinib for neurofibromatosis type 1-related plexiform neurofibromas: a phase 2 trial. Nat Med. 2021;27(1):165-173. doi:10.1038/s41591-020-01193-6; https://hdl.handle.net/1805/31057

الاتاحة: https://hdl.handle.net/1805/31057

المؤلفون: Li, Fang, Downing, Brandon D., Smiley, Lucy C., Mund, Julie A., DiStasi, Matthew R., Bessler, Waylan K., Sarchet, Kara N., Hinds, Daniel M., Kamendulis, Lisa M., Hingtgen, Cynthia M., Case, Jamie, Clapp, D. Wade, Conway, Simon J., Stansfield, Brian K., Ingram, David A.

المصدر: Circulation ; volume 129, issue 11, page 1213-1224 ; ISSN 0009-7322 1524-4539

الاتاحة: http://dx.doi.org/10.1161/circulationaha.113.006320
https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.113.006320

المؤلفون: Stansfield, Brian K., Bessler, Waylan K., Mali, Raghuveer, Mund, Julie A., Downing, Brandon D., Kapur, Reuben, Ingram, David A.

المصدر: The American Journal of Pathology ; volume 184, issue 1, page 79-85 ; ISSN 0002-9440

الاتاحة: http://dx.doi.org/10.1016/j.ajpath.2013.09.022
https://api.elsevier.com/content/article/PII:S0002944013006792?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0002944013006792?httpAccept=text/plain

المؤلفون: Stansfield, Brian K., Bessler, Waylan K., Mali, Raghuveer, Mund, Julie A., Downing, Brandon, Li, Fang, Sarchet, Kara N., DiStasi, Matthew R., Conway, Simon J., Kapur, Reuben, Ingram, David A.

مصطلحات موضوعية: ARTICLES

وصف الملف: text/html

Relation: http://hmg.oxfordjournals.org/cgi/content/short/22/5/977; http://dx.doi.org/10.1093/hmg/dds502

الاتاحة: http://hmg.oxfordjournals.org/cgi/content/short/22/5/977
https://doi.org/10.1093/hmg/dds502

المؤلفون: Lasater, Elisabeth A., Bessler, Waylan K., Mead, Laura E., Horn, Whitney E., Clapp, D. Wade, Conway, Simon J., Ingram, David A., Li, Fang

مصطلحات موضوعية: Article

وصف الملف: text/html

Relation: http://hmg.oxfordjournals.org/cgi/content/short/ddn134v1; http://dx.doi.org/10.1093/hmg/ddn134

الاتاحة: http://hmg.oxfordjournals.org/cgi/content/short/ddn134v1
https://doi.org/10.1093/hmg/ddn134

المؤلفون: Javed, M Jawad, Mead, Laura E, Prater, Daniel, Bessler, Waylan K, Foster, David, Case, Jamie, Goebel, W Scott, Yoder, Mervin C, Haneline, Laura S, Ingram, David A

المصدر: Pediatric Research ; volume 64, issue 1, page 68-73 ; ISSN 0031-3998 1530-0447

الاتاحة: http://dx.doi.org/10.1203/pdr.0b013e31817445e9

المؤلفون: Case, Jamie, Mead, Laura E., Bessler, Waylan K., Prater, Daniel, White, Hilary A., Saadatzadeh, M. Reza, Bhavsar, Janak R., Yoder, Mervin C., Haneline, Laura S., Ingram, David A.

المصدر: Experimental Hematology ; volume 35, issue 7, page 1109-1118 ; ISSN 0301-472X

الاتاحة: http://dx.doi.org/10.1016/j.exphem.2007.04.002
https://api.elsevier.com/content/article/PII:S0301472X07002251?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0301472X07002251?httpAccept=text/plain

المؤلفون: Burks, Ciersten A., Rhodes, Steven D., Bessler, Waylan K., Chen, Shi, Smith, Abbi, Gehlhausen, Jeffrey R., Hawley, Eric T., Jiang, Li, Li, Xiaohong, Yuan, Jin, Lu, Qingbo, Jacobsen, Max, Sandusky, George E., Jones, David R., Clapp, D. Wade, Blakeley, Jaishri O.

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: neurofibromatosis type 1, NF1, plexiform neurofibroma, ketotifen

وصف الملف: application/pdf

Relation: Molecular Cancer Therapeutics; Burks, C. A., Rhodes, S. D., Bessler, W. K., Chen, S., Smith, A., Gehlhausen, J. R., Hawley, E. T., Jiang, L., Li, X., Yuan, J., Lu, Q., Jacobsen, M., Sandusky, G. E., Jones, D. R., Clapp, D. W., & Blakeley, J. O. (2019). Ketotifen Modulates Mast Cell Chemotaxis to Kit-Ligand, but Does Not Impact Mast Cell Numbers, Degranulation, or Tumor Behavior in Neurofibromas of Nf1-Deficient Mice. Molecular Cancer Therapeutics, 18(12), 2321–2330. https://doi.org/10.1158/1535-7163.MCT-19-0123; 1535-7163, 1538-8514; https://hdl.handle.net/1805/26042

الاتاحة: https://hdl.handle.net/1805/26042

المؤلفون: Allen, Jayme D, Jaffer, Zahara M, Park, Su-Jung, Burgin, Sarah, Hofmann, Clemens, Sells, Mary A, Chen, Shi, Derr-Yellin, Ethel, Michels, Elizabeth G, McDaniel, Andrew, Bessler, Waylan K, Ingram, David A, Atkinson, Simon J, Travers, Jeffrey B, Chemoff, Jonathan, Clapp, D Wade

مصطلحات موضوعية: mast cells, Pak1, allergic diseasis

وصف الملف: application/pdf

Relation: Allen, J. D., Jaffer, Z. M., Park, S. J., Burgin, S., Hofmann, C., Sells, M. A., . & Clapp, D. W. (2009). p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics. Blood, 113(12), 2695-2705.; https://hdl.handle.net/1805/4162

الاتاحة: https://hdl.handle.net/1805/4162

المؤلفون: Bessler, Waylan K., Kim, Grace, Hudson, Farlyn Z., Mund, Julie A., Mali, Raghuveer, Menon, Keshav, Kapur, Reuben, Clapp, D. Wade, Ingram Jr, David A., Stansfield, Brian K.

المصدر: Human Molecular Genetics; 3/15/2016, Vol. 25 Issue 6, p1129-1139, 11p

المؤلفون: Fang Li, Downing, Brandon D., Smiley, Lucy C., Mund, Julie A., DiStasi, Matthew R., Bessler, Waylan K., Sarchet, Kara N., Hinds, Daniel M., Kamendulis, Lisa M., Hingtgen, Cynthia M., Case, Jamie, Clapp, D. Wade, Conway, Simon J., Stansfield, Brian K., Ingram Jr., David A.

المصدر: Circulation; 3/18/2014, Vol. 129 Issue 11, p1213-1224, 12p

المؤلفون: Lasater, Elisabeth A., Bessler, Waylan K., Mead, Laura E., Horn, Whitney E., Clapp, D. Wade, Conway, Simon J., Ingram, David A., Li, Fang

المصدر: Human Molecular Genetics; Aug2008, Vol. 17 Issue 15, p2336-2344, 9p

المؤلفون: Stansfield, Brian K., Bessler, Waylan K., Mali, Raghuveer, Mund, Julie A., Downing, Brandon D., Kapur, Reuben, Ingram, David A.

المصدر: American Journal of Pathology; January 2014, Vol. 184 Issue: 1 p79-85, 7p

المؤلفون: Allen, Jayme D., Jaffer, Zahara M., Park, Su-Jung, Burgin, Sarah, Hofmann, Clemens, Sells, Mary Ann, Chen, Shi, Derr-Yellin, Ethel, Michels, Elizabeth G., McDaniel, Andrew, Bessler, Waylan K., Ingram, David A., Atkinson, Simon J., Travers, Jeffrey B., Chernoff, Jonathan, Clapp, D. Wade

المصدر: Blood; March 2009, Vol. 113 Issue: 12 p2695-2705, 11p