المؤلفون: Chiara Lago, Aniello Federico, Gloria Leva, Norman L Mack, Benjamin Schwalm, Claudio Ballabio, Matteo Gianesello, Luana Abballe, Isabella Giovannoni, Sofia Reddel, Sabrina Rossi, Nicolas Leone, Andrea Carai, Angela Mastronuzzi, Alessandra Bisio, Alessia Soldano, Concetta Quintarelli, Franco Locatelli, Marcel Kool, Evelina Miele, Luca Tiberi

المصدر: EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-28 (2023)

مصطلحات موضوعية: brain tumors, organoids, patient‐derived, pediatric cancer, translational applications, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/27709dc824264046a65fac5ef01127a4

المؤلفون: Marieke Gringmuth, Jenny Walther, Sebastian Greiser, Magali Toussaint, Benjamin Schwalm, Marcel Kool, Rolf-Dieter Kortmann, Annegret Glasow, Ina Patties

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3815

مصطلحات موضوعية: medulloblastoma, radiation, decitabine, abacavir, in vivo study, magnetic resonance imaging, T2 mapping, bioluminescence imaging, gene expression microarray

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Neurobiology; https://dx.doi.org/10.3390/ijms23073815

الاتاحة: https://doi.org/10.3390/ijms23073815

المؤلفون: Apurva Gopisetty, Aniello Federico, Didier Surdez, Yasmine Iddir, Sakina Zaidi, Alexandra Saint-Charles, Joshua Waterfall, Elnaz Saberi-Ansari, Justyna Wierzbinska, Andreas Schlicker, Norman Mack, Benjamin Schwalm, Christopher Previti, Lena Weiser, Ivo Buchhalter, Anna-Lisa Böttcher, Martin Sill, Robert Autry, Frank Estermann, David Jones, Richard Volckmann, Danny Zwijnenburg, Angelika Eggert, Olaf Heidenreich, Fatima Iradier, Irmela Jeremias, Heinrich Kovar, Jan-Henning Klusmann, Klaus-Michael Debatin, Simon Bomken, Petra Hamerlik, Maureen Hattersley, Olaf Witt, Louis Chesler, Alan Mackay, Johannes Gojo, Stefano Cairo, Julia Schueler, Johannes Schulte, Birgit Geoerger, Jan J. Molenaar, David J. Shields, Hubert N. Caron, Gilles Vassal, Louis F. Stancato, Stefan M. Pfister, Natalie Jaeger, Jan Koster, Marcel Kool, Gudrun Schleiermacher

المصدر: Cancer Research. 83:234-234

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f9f689ca14428d824522f9a30f511100
https://doi.org/10.1158/1538-7445.am2023-234

المؤلفون: Apurva Gopisetty, Aniello Federico, Didier Surdez, Elnaz Saberi-Ansari, Yasmine Iddir, Alexandra Saint-Charles, Joshua Waterfall, Justyna Wierzbinska, Andreas Schlicker, Norman Mack, Benjamin Schwalm, David T Jones, Johannes Gojo, Louis Chesler, Gilles Vassal, Lou Stancato, Jan Koster, Jan J Molenaar, Natalie Jaeger, Gudrun Schleiermacher, Stefan Pfister, Marcel Kool

المصدر: Neuro-Oncology. 24:vii126-vii127

مصطلحات موضوعية: Cancer Research, Oncology, Neurology (clinical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9c43a31fe055855349266fd37f77f0de
https://doi.org/10.1093/neuonc/noac209.481

المؤلفون: Simon Feyerabend, Thorsten Rieckmann, Britta Riepen, Agnes Oetting, Sabrina Christiansen, Melanie Schoof, Annika Hardt, Sabrina Köcher, Julia Neumann, Rudolf Schwarz, Norman Mack, Benjamin Schwalm, Aniello Federico, Till Milde, Marcel Kool, Ulrich Schüller, Stefan Rutkowski, Cordula Petersen, Kai Rothkamm, Martin Mynarek, Nina Struve

المصدر: Neuro-Oncology. 24:i117-i118

مصطلحات موضوعية: Cancer Research, Oncology, Neurology (clinical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b99de9f98d6107b7c41efee516ea917e
https://doi.org/10.1093/neuonc/noac079.424

المؤلفون: Sonja Krausert, Norman Mack, Benjamin Schwalm, Heike Peterziel, Ina Oehme, Cornelis M van Tilburg, Olaf Witt, Stefan M Pfister, Marcel Kool

المصدر: Neuro-Oncology. 24:i168-i168

مصطلحات موضوعية: Cancer Research, Oncology, Neurology (clinical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0a47eee29ef11496958c015b1ab8010e
https://doi.org/10.1093/neuonc/noac079.624

المؤلفون: Marcel Kool, Aniello Federico, Didier Surdez, Apurva Gopisetty, Elnaz Saberi-Ansari, Alexandra Saint-Charles, Yasmine Iddir, Joshua Waterfall, Justyna Wierzbinska, Andreas Schlicker, Jaydutt Bhalsankar, Norman Mack, Benjamin Schwalm, Anna-Lisa Böttcher, Martin Sill, Frank Westermann, David T W Jones, Richard Volckmann, Danny Zwijnenburg, Dennis Gürgen, Emilie Inderise, Johannes Schulte, Angelika Eggert, Jan J Molenaar, Olivier Delattre, Sara Colombetti, Olaf Heidenreich, Irmela Jeremias, Katia Scotlandi, Maria Cristina Manara, Johannes Gojo, Walter Berger, Fatima Iradier, Birgit Geoerger, Jenny Costa, Beat Schäfer, Marco Wachtel, Louis Chesler, Chris Jones, Heinrich Kovar, Ángel Montero Carcaboso, Jan-Henning Klusmann, Klaus-Michael Debatin, Simon Bomken, Christina Guttke, Petra Hamerlik, Maureen Hattersley, Michelle Garcia, Frédéric Colland, Ashley Strougo, Olaf Witt, Gilles Vassal, Hubert Caron, David J Shields, Lou F Stancato, Pablo M Aviles, Jens Hoffmann, Stefano Cairo, Julia Schueler, Natalie Jäger, Jan Koster, Gudrun Schleiermacher, Stefan M Pfister

المصدر: Neuro-Oncology. 24:i189-i189

مصطلحات موضوعية: Cancer Research, Oncology, Neurology (clinical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0ae29eeb04131d53a4fafa97de70f2df
https://doi.org/10.1093/neuonc/noac079.711

المؤلفون: Zelda Odé, Joris Maas, Mieke Roosen, Phylicia Stathi, Aniello Federico, Norman Mack, Benjamin Schwalm, Jens Bunt, Marcel Kool

المصدر: Neuro-Oncology. 24:i118-i118

مصطلحات موضوعية: Cancer Research, Oncology, Neurology (clinical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f523bc96a7a27bb2da2dbec0b850a288
https://doi.org/10.1093/neuonc/noac079.426

المؤلفون: Kristian W. Pajtler, Ilon Liu, Volker Hovestadt, Aviv Regev, Walter Berger, Marni E. Shore, Kristine Pelton, Lisa Mayr, Till Milde, Sanda Alexandrescu, Sibylle Madlener, Nathan Mathewson, Mariella G. Filbin, Christine Haberler, McKenzie Shaw, Jason Pyrdol, Emanuele Mazzola, Daniela Lötsch, Jack Geduldig, Maria Trissal, Orr Ashenberg, Jens Martin Hübner, Andreas Peyrl, Li Jiang, Monica Mauermann, Benjamin Schwalm, Mario L. Suvà, Dominik Kirchhofer, Johannes Gojo, Keith L. Ligon, Stefan M. Pfister, Kai W. Wucherpfennig, Bernhard Englinger, Angela Halfmann, Christian Dorfer, Irene Slavc, Orit Rozenblatt-Rosen, Marcel Kool, René Geyeregger, Olivia A Hack, Thomas Czech

المصدر: Neuro Oncol

مصطلحات موضوعية: Cancer Research, medicine.anatomical_structure, Oncology, Cell, Cancer research, medicine, Pediatric ependymoma, RNA-Seq, Neurology (clinical), Biology, (Epi)Genetics and Computational Omics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c39486d23d0ca5744829963214f603
https://europepmc.org/articles/PMC7651434/

المؤلفون: Volker Hovestadt, Paul A. Northcott, Kyle Pedro, Sebastian Brabetz, Susanne Gröbner, Gnana Prakash Balasubramanian, Stefan M. Pfister, Huriye Seker-Cin, Sarah Leary, Peter Lichter, Karina Bloom, Madison W. Nakamoto, Jan Koster, Andrey Korshunov, Stacey Hansen, Joyoti Dey, Andrew D. Strand, Marcel Kool, Bonnie Cole, Fiona Pakiam, Emily J. Girard, Norman Mack, David T.W. Jones, Lukas Chavez, Sally Ditzler, Benjamin Schwalm, James M. Olson

المساهمون: Oncogenomics, CCA - Imaging and biomarkers

المصدر: Nature Medicine
Nature medicine, 24(11), 1752-1761. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Male, Genomics, medicine.disease_cause, Pediatrics, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, In vivo, Cell Line, Tumor, medicine, Animals, Humans, Child, Biological Specimen Banks, Mutation, business.industry, Brain Neoplasms, Cancer, General Medicine, DNA Methylation, medicine.disease, Biobank, Immunohistochemistry, Xenograft Model Antitumor Assays, 3. Good health, 030104 developmental biology, Child, Preschool, DNA methylation, Cancer research, Pediatric Brain Tumor, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3e4bf3088822b533e30bb1e3cf8f76
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85055262681&origin=inward

المؤلفون: Christin Schmidt, Marcel Kool, Till Milde, Jennifer A. Chan, Sebastian Brabetz, Christel Herold-Mende, Benjamin Schwalm, Nil A. Schubert, Olaf Witt, Norman Mack, Andrey Korshunov, Florian Selt, Stefan M. Pfister

المصدر: Neuro-Oncology. 19:1607-1617

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Vincristine, medicine.drug_class, Decitabine, Apoptosis, Mice, SCID, Pharmacology, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Mice, Inbred NOD, Panobinostat, Tumor Cells, Cultured, medicine, Animals, Humans, Neuroectodermal Tumors, Primitive, Doxorubicin, Cell Proliferation, Antibiotics, Antineoplastic, Brain Neoplasms, business.industry, Pteridines, Cell Cycle, Volasertib, Neoplasms, Germ Cell and Embryonal, Xenograft Model Antitumor Assays, 030104 developmental biology, Oncology, chemistry, Child, Preschool, 030220 oncology & carcinogenesis, Basic and Translational Investigations, Alisertib, Dactinomycin, Cancer research, Female, Topotecan, Neurology (clinical), Topoisomerase I Inhibitors, business, Topoisomerase inhibitor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32214f066a836cad5e4cbb31d38b22df
https://doi.org/10.1093/neuonc/nox093

المؤلفون: Olaf Witt, Maria Łastowska, Anna Darabi, Ulrich Schüller, Andreas von Deimling, Nada Jabado, Susanne Gröbner, David Sumerauer, Annie Huang, Sebastian M. Waszak, Martin Sill, Xiao-Nan Li, Andrey Korshunov, Julien Masliah-Planchon, Pablo Landgraf, David Ellison, Maria J. Gil-da-Costa, Alexander J.R. Bishop, Christin Schmidt, Pieter Wesseling, Sebastian Brabetz, Marc Remke, July Carolina Romero, Dominique Figarella-Branger, Peter Hauser, Simon Papillon-Cavanagh, Jennifer A. Chan, Felix Sahm, Benjamin Schwalm, Peter Lichter, Ivo Buchhalter, Stephan Wolf, Norman Mack, Matthias A. Karajannis, Till Milde, Jan Koster, Valérie Rigau, Monika Mauermann, Matija Snuderl, Franck Bourdeaut, Christine Haberler, Torsten Pietsch, Volker Hovestadt, Wiesława Grajkowska, Katja von Hoff, Felice Giangaspero, Marcel Kool, Emmanuelle Uro-Coste, Jan O. Korbel, Michael D. Taylor, Martin Hasselblatt, Tobias Rausch, Danny A. Zwijnenburg, Jonas Ecker, Brent A. Orr, David T.W. Jones, Jens Schittenhelm, Aparna Gorthi, Sonja Krausert, Sanda Alexandrescu, Sander Lambo, Jens Martin Hübner, Ben Ho, Stefan M. Pfister, Marina Ryzhova

المساهمون: German Cancer Consortium [Heidelberg] (DKTK), Department of Oncogenomics [Amsterdam, Pays-Bas], Academic Medical Center - Academisch Medisch Centrum [Amsterdam] (AMC), University of Amsterdam [Amsterdam] (UvA)-University of Amsterdam [Amsterdam] (UvA), Heidelberg University Hospital [Heidelberg], Division of Medical Genetics [Seattle], University of Washington [Seattle], Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany, Department of Neuropathology, Institute of Pathology, RMIT Melbourne, Institut de neurophysiopathologie (INP), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Aix Marseille Université (AMU), Service d'Anatomie Pathologique et de Neuropathologie [Hôpital de la Timone - CHU - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), VU University Medical Center [Amsterdam], German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Pédiatrie et oncologie pédiatrique [Hôpital de la Timone - APHM], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Service d'anatomie pathologique et histologie-cytologie [Rangueil], Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Hôpital de Rangueil, CHU Toulouse [Toulouse], Unité de génétique et biologie des cancers (U830), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5), Pathologie cellulaire : aspects moléculaires et viraux / Pathologie et Virologie Moléculaire, Institut Universitaire d'Hématologie (IUH), Université Paris Diderot - Paris 7 (UPD7)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS), Institut des Neurosciences de Montpellier - Déficits sensoriels et moteurs (INM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Department of Pathology, Massachusetts General Hospital [Boston], Department of Human Genetics , Department of Experimental Medicine, Radboud University Medical Center [Nijmegen], European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany., Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany, Pathology, CCA - Imaging and biomarkers, Université Paris Diderot - Paris 7 (UPD7)-Université Paris Diderot - Paris 7 (UPD7)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Université Paris Descartes - Paris 5 (UPD5)-Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut des Neurosciences de Montpellier (INM), Université Paris Descartes - Paris 5 (UPD5)-Institut Curie-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Centre National de la Recherche Scientifique (CNRS), Oncogenomics

المصدر: Nature
Nature, Nature Publishing Group, 2019, 576 (7786), pp.274-280. ⟨10.1038/s41586-019-1815-x⟩
Nature, 576(7786), 274-280. Nature Publishing Group
Lambo, S, Gröbner, S N, Rausch, T, Waszak, S M, Schmidt, C, Gorthi, A, Romero, J C, Mauermann, M, Brabetz, S, Krausert, S, Buchhalter, I, Koster, J, Zwijnenburg, D A, Sill, M, Hübner, J-M, Mack, N, Schwalm, B, Ryzhova, M, Hovestadt, V, Papillon-Cavanagh, S, Chan, J A, Landgraf, P, Ho, B, Milde, T, Witt, O, Ecker, J, Sahm, F, Sumerauer, D, Ellison, D W, Orr, B A, Darabi, A, Haberler, C, Figarella-Branger, D, Wesseling, P, Schittenhelm, J, Remke, M, Taylor, M D, Gil-da-Costa, M J, Łastowska, M, Grajkowska, W, Hasselblatt, M, Hauser, P, Pietsch, T, Uro-Coste, E, Bourdeaut, F, Masliah-Planchon, J, Rigau, V, Alexandrescu, S, Wolf, S, Li, X-N, Schüller, U, Snuderl, M, Karajannis, M A, Giangaspero, F, Jabado, N, von Deimling, A, Jones, D T W, Korbel, J O, von Hoff, K, Lichter, P, Huang, A, Bishop, A J R, Pfister, S M, Korshunov, A & Kool, M 2019, ' The molecular landscape of ETMR at diagnosis and relapse ', Nature, vol. 576, no. 7786, pp. 274-280 . https://doi.org/10.1038/s41586-019-1815-x
Nature, 2019, 576 (7786), pp.274-280. ⟨10.1038/s41586-019-1815-x⟩

مصطلحات موضوعية: Ribonuclease III, 0301 basic medicine, Genome instability, medicine.medical_specialty, Somatic cell, [SDV]Life Sciences [q-bio], Disease, Poly(ADP-ribose) Polymerase Inhibitors, Polymorphism, Single Nucleotide, Article, DEAD-box RNA Helicases, 03 medical and health sciences, 0302 clinical medicine, Germline mutation, Recurrence, Chromosome instability, medicine, Humans, ComputingMilieux_MISCELLANEOUS, Cisplatin, Multidisciplinary, biology, embryonal tumours, Topoisomerase, brain tumours, genomic landscape, Neoplasms, Germ Cell and Embryonal, 3. Good health, MicroRNAs, 030104 developmental biology, DNA Topoisomerases, Type I, 030220 oncology & carcinogenesis, multilayered rosettes, Mutation, biology.protein, Cancer research, Medical genetics, RNA, Long Noncoding, Poly(ADP-ribose) Polymerases, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a9fb34e854ed244d44bc4f785f2b10
https://hal.archives-ouvertes.fr/hal-02441051

المؤلفون: Sander Lambo, Norman Mack, Marcel Kool, Sonja Krausert, Sebastian Brabetz, Stefan M. Pfister, Benjamin Schwalm

مصطلحات موضوعية: Medulloblastoma, Cancer Research, DNA repair, medicine.drug_class, DNA damage, business.industry, DNA replication, medicine.disease, Poly (ADP-Ribose) Polymerase Inhibitor, Oncology, Cell culture, medicine, Cancer research, Neurology (clinical), Stem cell, business, Translational Therapeutics, Topoisomerase inhibitor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96362d899f42788ab9fc33938dd870fb
https://europepmc.org/articles/PMC6477285/

المؤلفون: Norman Mack, Marcel Kool, Sonja Krausert, Stefan M. Pfister, Sander Lambo, Benjamin Schwalm

المصدر: Neuro-Oncology

مصطلحات موضوعية: Medulloblastoma, Cancer Research, Replication stress, business.industry, DNA replication, Brain tumor childhood, medicine.disease, Oncology, Pediatric brain, medicine, Cancer research, Inhibitory concentration 50, AcademicSubjects/MED00300, Tumor growth, AcademicSubjects/MED00310, Neurology (clinical), business, Preclinical Models/Experimental Therapy/Drug Discovery, Protein overexpression

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7600c860978484959c9552ce4ea351
http://europepmc.org/articles/PMC7715544

المؤلفون: Walter Berger, Lisa Mayr, Sibylle Madlener, Mario L. Suvà, Dominik Kirchhofer, Christine Haberler, Benjamin Schwalm, Ilon Liu, McKenzie Shaw, Orit Rozenblatt-Rosen, Marcel Kool, Volker Hovestadt, Emanuele Mazzola, Kristian W. Pajtler, Sanda Alexandrescu, Andreas Peyrl, Marni E. Shore, Daniela Lötsch, Jack Geduldig, Bernhard Englinger, Jason Pyrdol, Orr Ashenberg, René Geyeregger, Till Milde, Aviv Regev, Nathan Mathewson, Thomas Czech, Johannes Gojo, Jens Martin Hübner, Mariella G. Filbin, Olivia A Hack, Keith L. Ligon, Irene Slavc, Li Jiang, Monica Mauermann, Stefan M. Pfister, Christian Dorfer, Kai W. Wucherpfennig, Kristine Pelton, Angela Halfmann, Maria Trissal

المصدر: Cancer Cell

مصطلحات موضوعية: 0301 basic medicine, Ependymoma, cancer stem cells, Cancer Research, Cellular differentiation, Cell, RNA-Seq, Computational biology, Biology, aberrant development, Article, single-cell RNA sequencing, Central Nervous System Neoplasms, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Cancer stem cell, target identification, medicine, Humans, cellular hierarchy, Pediatric ependymoma, Child, Cell Proliferation, Neurons, Sequence Analysis, RNA, RNA, Cell Differentiation, Genomics, Cell Biology, Prognosis, medicine.disease, Survival Analysis, glial development, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, intratumoral heterogeneity, differentiation trajectory, Single-Cell Analysis, EPN

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4000cf5b5465364b24bb2feacfa87663