المؤلفون: Bassel Alsaed, Linh Lin, Jieun Son, Jiaqi Li, Johannes Smolander, Timothy Lopez, Pinar Ö. Eser, Atsuko Ogino, Chiara Ambrogio, Yoonji Eum, Tran Thai, Haiyun Wang, Eva Sutinen, Hilma Mutanen, Hanna Duàn, Nina Bobik, Kristian Borenius, William W. Feng, Behnam Nabet, Satu Mustjoki, Sanna Laaksonen, Benjamin K. Eschle, Michael J. Poitras, David Barbie, Ilkka Ilonen, Prafulla Gokhale, Pasi A. Jänne, Heidi M. Haikala

المصدر: Nature Communications, Vol 16, Iss 1, Pp 1-17 (2025)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c8a6f8fe8f964bb5979968858901dd63

المؤلفون: J. Bryan Iorgulescu, Neil Ruthen, Ryuhjin Ahn, Eleni Panagioti, Prafulla C. Gokhale, Martha Neagu, Maria C. Speranza, Benjamin K. Eschle, Kara M. Soroko, Raziye Piranlioglu, Meenal Datta, Shanmugarajan Krishnan, Kathleen B. Yates, Gregory J. Baker, Rakesh K. Jain, Mario L. Suvà, Donna Neuberg, Forest M. White, E. Antonio Chiocca, Gordon J. Freeman, Arlene H. Sharpe, Catherine J. Wu, David A. Reardon

المصدر: Frontiers in Immunology, Vol 14 (2023)

مصطلحات موضوعية: immunotherapy, resistance, mouse model, cancer, antigen presentation machinery, glioblastoma, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1297932/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/0d4ef411871943b490bc6d2c4f558fb2

المؤلفون: Eytan Ben-Ami, Raul Perret, Ying Huang, Félicie Courgeon, Prafulla C. Gokhale, Audrey Laroche-Clary, Benjamin K. Eschle, Valérie Velasco, François Le Loarer, Marie-Paule Algeo, James Purcell, George D. Demetri, Antoine Italiano

المصدر: Cancers; Volume 12; Issue 3; Pages: 757

مصطلحات موضوعية: LRRC15, sarcoma, ABBV-085

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cancers12030757

الاتاحة: https://doi.org/10.3390/cancers12030757

المؤلفون: Christopher A. French, Madeleine E. Lemieux, Philip A. Cole, Beth E. Zucconi, Geoffrey I. Shapiro, Bill Brown, Andrew Griffin, Francis Giles, Prafulla C. Gokhale, Margaret K. Wilkens, Benjamin K. Eschle, Kara M. Soroko, Ivona Filic, Tatiana M. Knox, Chevaun D. Morrison-Smith

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443954089c12bc613ff9662283e9aeac
https://doi.org/10.1158/1535-7163.c.6542821.v1

المؤلفون: Christopher A. French, Madeleine E. Lemieux, Philip A. Cole, Beth E. Zucconi, Geoffrey I. Shapiro, Bill Brown, Andrew Griffin, Francis Giles, Prafulla C. Gokhale, Margaret K. Wilkens, Benjamin K. Eschle, Kara M. Soroko, Ivona Filic, Tatiana M. Knox, Chevaun D. Morrison-Smith

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ce5c6c0f1f31ef00393d18c6eef31b
https://doi.org/10.1158/1535-7163.22520881.v1

المؤلفون: Christopher A. French, Madeleine E. Lemieux, Philip A. Cole, Beth E. Zucconi, Geoffrey I. Shapiro, Bill Brown, Andrew Griffin, Francis Giles, Prafulla C. Gokhale, Margaret K. Wilkens, Benjamin K. Eschle, Kara M. Soroko, Ivona Filic, Tatiana M. Knox, Chevaun D. Morrison-Smith

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a1f4894b3d5165744e623dd4428b44
https://doi.org/10.1158/1535-7163.22520908.v1

المؤلفون: Christopher A. French, Madeleine E. Lemieux, Philip A. Cole, Beth E. Zucconi, Geoffrey I. Shapiro, Bill Brown, Andrew Griffin, Francis Giles, Prafulla C. Gokhale, Margaret K. Wilkens, Benjamin K. Eschle, Kara M. Soroko, Ivona Filic, Tatiana M. Knox, Chevaun D. Morrison-Smith

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa6ffe4170e4aef0664906df6b39bbf0
https://doi.org/10.1158/1535-7163.22520902

المؤلفون: Christopher A. French, Madeleine E. Lemieux, Philip A. Cole, Beth E. Zucconi, Geoffrey I. Shapiro, Bill Brown, Andrew Griffin, Francis Giles, Prafulla C. Gokhale, Margaret K. Wilkens, Benjamin K. Eschle, Kara M. Soroko, Ivona Filic, Tatiana M. Knox, Chevaun D. Morrison-Smith

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbe62cc2bffe5c35fe4144d12b0bef5
https://doi.org/10.1158/1535-7163.22520890.v1

المؤلفون: David A. Reardon, Gordon J. Freeman, Arlene H. Sharpe, Paul T. Kirschmeier, Ana C. Anderson, E. Antonio Chiocca, Peter K. Sorger, Keith L. Ligon, Gareth R. L. Grant, Quang-Dé Nguyen, Dennis M. Bonal, Gregory J. Baker, Mary Jane Lim-Fat, Yan Gao, Aine Knott, Chhayheng Chhoeu, Kara M. Soroko, Margaret K. Wilkens, Michael J. Poitras, Benjamin K. Eschle, Maria C. Speranza, Prafulla C. Gokhale, J. Bryan Iorgulescu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4950c14fe70a319b92a2a2bee802702
https://doi.org/10.1158/1078-0432.22479228

المؤلفون: David A. Reardon, Gordon J. Freeman, Arlene H. Sharpe, Paul T. Kirschmeier, Ana C. Anderson, E. Antonio Chiocca, Peter K. Sorger, Keith L. Ligon, Gareth R. L. Grant, Quang-Dé Nguyen, Dennis M. Bonal, Gregory J. Baker, Mary Jane Lim-Fat, Yan Gao, Aine Knott, Chhayheng Chhoeu, Kara M. Soroko, Margaret K. Wilkens, Michael J. Poitras, Benjamin K. Eschle, Maria C. Speranza, Prafulla C. Gokhale, J. Bryan Iorgulescu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9e886220389a10bda3ab03ada9be3e
https://doi.org/10.1158/1078-0432.c.6530154.v1

المؤلفون: David A. Reardon, Gordon J. Freeman, Arlene H. Sharpe, Paul T. Kirschmeier, Ana C. Anderson, E. Antonio Chiocca, Peter K. Sorger, Keith L. Ligon, Gareth R. L. Grant, Quang-Dé Nguyen, Dennis M. Bonal, Gregory J. Baker, Mary Jane Lim-Fat, Yan Gao, Aine Knott, Chhayheng Chhoeu, Kara M. Soroko, Margaret K. Wilkens, Michael J. Poitras, Benjamin K. Eschle, Maria C. Speranza, Prafulla C. Gokhale, J. Bryan Iorgulescu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2a869aad70edd863de830b1bd54456
https://doi.org/10.1158/1078-0432.22479219

المؤلفون: David A. Reardon, Gordon J. Freeman, Arlene H. Sharpe, Paul T. Kirschmeier, Ana C. Anderson, E. Antonio Chiocca, Peter K. Sorger, Keith L. Ligon, Gareth R. L. Grant, Quang-Dé Nguyen, Dennis M. Bonal, Gregory J. Baker, Mary Jane Lim-Fat, Yan Gao, Aine Knott, Chhayheng Chhoeu, Kara M. Soroko, Margaret K. Wilkens, Michael J. Poitras, Benjamin K. Eschle, Maria C. Speranza, Prafulla C. Gokhale, J. Bryan Iorgulescu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b95f2725d8e00b91b7907f7172b9265
https://doi.org/10.1158/1078-0432.22479216.v1

المؤلفون: J. Bryan Iorgulescu, Neil Ruthen, Ryuhjin Ahn, Eleni Panagioti, Prafulla C. Gokhale, Martha Neagu, Maria C. Speranza, Benjamin K. Eschle, Kara M. Soroko, Raziye Piranlioglu, Meenal Datta, Shanmugarajan Krishnan, Kathleen B. Yates, Gregory J. Baker, Rakesh K. Jain, Mario L. Suvà, Donna Neuberg, Forest M. White, E. Antonio Chiocca, Gordon J. Freeman, Arlene H. Sharpe, Catherine J. Wu, David A. Reardon

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, immunotherapy, resistance, mouse model, cancer, antigen presentation machinery, glioblastoma, mesenchymal

Relation: https://figshare.com/articles/dataset/Table_2_Antigen_presentation_deficiency_mesenchymal_differentiation_and_resistance_to_immunotherapy_in_the_murine_syngeneic_CT2A_tumor_model_docx/24912783

الاتاحة: https://doi.org/10.3389/fimmu.2023.1297932.s003
https://figshare.com/articles/dataset/Table_2_Antigen_presentation_deficiency_mesenchymal_differentiation_and_resistance_to_immunotherapy_in_the_murine_syngeneic_CT2A_tumor_model_docx/24912783

المؤلفون: J. Bryan Iorgulescu, Neil Ruthen, Ryuhjin Ahn, Eleni Panagioti, Prafulla C. Gokhale, Martha Neagu, Maria C. Speranza, Benjamin K. Eschle, Kara M. Soroko, Raziye Piranlioglu, Meenal Datta, Shanmugarajan Krishnan, Kathleen B. Yates, Gregory J. Baker, Rakesh K. Jain, Mario L. Suvà, Donna Neuberg, Forest M. White, E. Antonio Chiocca, Gordon J. Freeman, Arlene H. Sharpe, Catherine J. Wu, David A. Reardon

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, immunotherapy, resistance, mouse model, cancer, antigen presentation machinery, glioblastoma, mesenchymal

Relation: https://figshare.com/articles/dataset/DataSheet_1_Antigen_presentation_deficiency_mesenchymal_differentiation_and_resistance_to_immunotherapy_in_the_murine_syngeneic_CT2A_tumor_model_pdf/24912777

الاتاحة: https://doi.org/10.3389/fimmu.2023.1297932.s001
https://figshare.com/articles/dataset/DataSheet_1_Antigen_presentation_deficiency_mesenchymal_differentiation_and_resistance_to_immunotherapy_in_the_murine_syngeneic_CT2A_tumor_model_pdf/24912777

المؤلفون: Bill Brown, Griffin Andrew, Chevaun Morrison-Smith, Christopher A. French, Ivona Filic, Francis J. Giles, Kara M. Soroko, Beth E. Zucconi, Philip A. Cole, Benjamin K. Eschle, Margaret K. Wilkens, Madeleine E. Lemieux, Tatiana M. Knox, Prafulla C. Gokhale, Geoffrey I. Shapiro

المصدر: Molecular Cancer Therapeutics. 19:1406-1414

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, BRD4, Pyridones, Antineoplastic Agents, Apoptosis, Cell Cycle Proteins, Mice, SCID, BET inhibitor, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Mice, Inbred NOD, Biomarkers, Tumor, Tumor Cells, Cultured, medicine, Animals, Humans, Cell Proliferation, NUT midline carcinoma, biology, Chemistry, Cell growth, Carcinoma, Cell Cycle, Nuclear Proteins, hemic and immune systems, medicine.disease, Xenograft Model Antitumor Assays, Neoplasm Proteins, Squamous carcinoma, Bromodomain, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Histone, Oncology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Benzimidazoles, Growth inhibition, E1A-Associated p300 Protein, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58b293960287f904cae743b0a5c9b89
https://doi.org/10.1158/1535-7163.mct-20-0087

المؤلفون: Benjamin K. Eschle, Michael J. Poitras, Max Klapholz, Bryan Iorgulescu, Ana C. Anderson, Gordon J. Freeman, Prafulla C. Gokhale, David A. Reardon

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

مصطلحات موضوعية: Pharmacology, Cancer Research, biology, business.industry, CD226, Immunology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Blockade, Oncology, TIGIT, PD-L1, Cancer research, biology.protein, Molecular Medicine, Immunology and Allergy, Medicine, CD155, business, Antibody therapy, RC254-282, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac127ea4415edd8e5554d72efeb6837
https://doaj.org/article/fae34122fb9a4fdab824c6ef226b0e76

المؤلفون: Nauman M. Javed, Jason L. Hornick, Ewa Sicinska, Bradley E. Bernstein, Prafulla C. Gokhale, Benjamin K. Eschle, George D. Demetri, Esmat Hegazi, Matthew L. Hemming, Daniel R. Tarjan, Chandrajit P. Raut, Yotam Drier, Sarah J. Shareef, William A. Flavahan, Sarah E. Johnstone

المصدر: Nature

مصطلحات موضوعية: 0301 basic medicine, Carcinogenesis, Gastrointestinal Stromal Tumors, Fibroblast Growth Factor 4, PDGFRA, Biology, Topology, Article, Epigenesis, Genetic, Mice, 03 medical and health sciences, 0302 clinical medicine, Animals, Humans, Epigenetics, Enhancer, Kit oncogene, Chromosome Aberrations, Regulation of gene expression, Multidisciplinary, Oncogene, Oncogenes, DNA Methylation, Receptors, Fibroblast Growth Factor, digestive system diseases, Succinate Dehydrogenase, Proto-Oncogene Proteins c-kit, Enhancer Elements, Genetic, 030104 developmental biology, CTCF, 030220 oncology & carcinogenesis, Mutation, DNA methylation, CRISPR-Cas Systems

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e025a723c36f280f5610b300e74df6
https://doi.org/10.1038/s41586-019-1668-3

المؤلفون: Arlene H. Sharpe, J. Bryan Iorgulescu, Yan Gao, Benjamin K. Eschle, Gregory J. Baker, Michael J. Poitras, Gareth Grant, E. Antonio Chiocca, Ana C. Anderson, Keith L. Ligon, Prafulla C. Gokhale, Peter K. Sorger, Paul Kirschmeier, Quang-Dé Nguyen, Gordon J. Freeman, Margaret K. Wilkens, Maria C. Speranza, Dennis M. Bonal, David A. Reardon, Aine Knott, Kara M. Soroko, Mary Jane Lim-Fat, Chhayheng Chhoeu

المصدر: Clin Cancer Res

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Myeloid, medicine.drug_class, medicine.medical_treatment, Lymphocyte, Programmed Cell Death 1 Receptor, Context (language use), Brain Edema, Kaplan-Meier Estimate, Article, B7-H1 Antigen, Dexamethasone, 03 medical and health sciences, Mice, 0302 clinical medicine, Internal medicine, Cell Line, Tumor, medicine, Tumor Microenvironment, Animals, Humans, Drug Interactions, Immune Checkpoint Inhibitors, Retrospective Studies, Dose-Response Relationship, Drug, business.industry, Brain Neoplasms, Immunotherapy, Chemoradiotherapy, Prognosis, Immune checkpoint, Isocitrate Dehydrogenase, Blockade, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Corticosteroid, Female, business, Glioblastoma, medicine.drug, Follow-Up Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d722197c05cd6898409bb4427e1db892
https://europepmc.org/articles/PMC8034990/

المؤلفون: David A. Reardon, Aine Knott, Michael J. Poitras, Yang Gao, Benjamin K. Eschle, Gregory L. Baker, E. Antonio Chiocca, Maria C. Speranza, Prafulla C. Gokhale, Chhayheng Chhoeu, Arlene H. Sharpe, Bryan Iorgulescu, Gordon J. Freeman, Peter K. Sorger, Quang-Dé Nguyen, Gareth Grant, Margaret K. Wilkens, Dennis M. Bonal, Keith L. Ligon, Paul Kirschmeier, Mary Jane Lim-Fat, Kara M. Soroko, Ana C. Anderson

المصدر: Neuro Oncol

مصطلحات موضوعية: Cancer Research, business.industry, Immunology, medicine.disease, Immune checkpoint, Blockade, Oncology, medicine, Cancer research, Neurology (clinical), business, Dexamethasone, Glioblastoma, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3555f4ce6971c62bf20c2a1b31f17495
https://europepmc.org/articles/PMC7651662/

المؤلفون: Paul Kirschmeier, Benjamin K. Eschle, Gareth Grant, Chhayheng Chhoeu, Peter K. Sorger, Maria C. Speranza, Yan Gao, Ennio Antonio Chiocca, Keith L. Ligon, Ana C. Anderson, Prafulla C. Gokhale, Quang-Dé Nguyen, Mary Jane Lim-Fat, Kara M. Soroko, Dennis M. Bonal, Gordon J. Freeman, Margaret K. Wilkens, Gregory L. Baker, Michael J. Poitras, Bryan Iorgulescu, Aine Knott, David A. Reardon, Arlene H. Sharpe

المصدر: Regular and young investigator award abstracts.

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Myeloid, business.industry, medicine.drug_class, Lymphocyte, medicine.medical_treatment, Immunotherapy, Immune checkpoint, Blockade, medicine.anatomical_structure, Immune system, Internal medicine, medicine, Corticosteroid, business, Dexamethasone, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::33ef589a06f5528184bfad4cb8430157
https://doi.org/10.1136/jitc-2020-sitc2020.0209