المؤلفون: Rodon, J., Arkenau, H-T., Funchain, P., Hervieu, A., Gao, L., Liu, M., Halim, A., Mina, M., Takahashi, O., Benhadji, K., Delaloge, S.

المصدر: Annals of Oncology ; volume 33, page S754-S755 ; ISSN 0923-7534

الاتاحة: http://dx.doi.org/10.1016/j.annonc.2022.07.596
https://api.elsevier.com/content/article/PII:S0923753422024474?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0923753422024474?httpAccept=text/plain

المؤلفون: Even, C., Lassen, U., Merchan, J., Le Tourneau, C., Soria, J. C., Ferte, C., Ricci, F., Diener, J. T., Yuen, E., Smith, C., Oakley, G. J., Benhadji, K. A., Massard, Christophe

المصدر: Even , C , Lassen , U , Merchan , J , Le Tourneau , C , Soria , J C , Ferte , C , Ricci , F , Diener , J T , Yuen , E , Smith , C , Oakley , G J , Benhadji , K A & Massard , C 2020 , ' Safety and clinical activity of the Notch inhibitor, crenigacestat (LY3039478), in an open-label phase I trial expansion cohort of advanced or metastatic adenoid cystic carcinoma ' , Investigational New Drugs , vol. 38 , no. 2 , pp. 402-409 . ....

مصطلحات موضوعية: Adenoid cystic carcinoma, Crenigacestat, LY3039478, Notch pathway, Phase 1

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/safety-and-clinical-activity-of-the-notch-inhibitor-crenigacestat-ly3039478-in-an-openlabel-phase-i-trial-expansion-cohort-of-advanced-or-metastatic-adenoid-cystic-carcinoma(97fc7123-202e-49ae-a1d4-4e47cf38b1d4).html
https://doi.org/10.1007/s10637-019-00739-x
https://curis.ku.dk/ws/files/249477116/Safety_and_clinical_activity_of_the_Notch_inhibitor_crenigacestat.pdf
http://www.scopus.com/inward/record.url?scp=85072038678&partnerID=8YFLogxK

المؤلفون: Bridgewater, J., Meric-Bernstam, F., Hollebecque, A., Valle, J.W., Morizane, C., Karasic, T., Abrams, T., Furuse, J., Kelley, R.K., Cassier, P., Klümpen, H-J., Uboha, N., Mahipal, A., Mitchell, E., Ahn, E.R., Chang, H-M., Masuda, K., He, Y., Benhadji, K., Goyal, L.

المصدر: Annals of Oncology ; volume 31, page S261-S262 ; ISSN 0923-7534

الاتاحة: http://dx.doi.org/10.1016/j.annonc.2020.08.032
https://api.elsevier.com/content/article/PII:S0923753420400286?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0923753420400286?httpAccept=text/plain

المؤلفون: Valle, J.W., Hollebecque, A., Furuse, J., Goyal, L., Meric-Bernstam, F., Morlock, R., He, Y., Benhadji, K., Bridgewater, J.

المصدر: Annals of Oncology ; volume 31, page S263-S264 ; ISSN 0923-7534

الاتاحة: http://dx.doi.org/10.1016/j.annonc.2020.08.036
https://api.elsevier.com/content/article/PII:S0923753420400328?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0923753420400328?httpAccept=text/plain

المؤلفون: Ghidini, M., Hochster, H., Doi, T., Van Cutsem, E., Makris, L., Takahashi, O., Benhadji, K. A., Mansoor, Was

المساهمون: Oncology Division, Azienda Socio Sanitaria Territoriale di Cremona, Azienda Ospedaliera di Cremona, Viale Concordia 1, 26100, Cremona, Italy

Relation: https://dx.doi.org/10.1007/s10120-023-01393-2; Ghidini M, Hochster H, Doi T, Van Cutsem E, Makris L, Takahashi O, et al. Body weight loss as a prognostic and predictive factor in previously treated patients with metastatic gastric cancer: post hoc analyses of the randomized phase III TAGS trial. Gastric Cancer. 2023 Apr 28. PubMed PMID: 37106214. Epub 2023/04/28. eng.; http://hdl.handle.net/10541/626254; Gastric Cancer

الاتاحة: http://hdl.handle.net/10541/626254
https://doi.org/10.1007/s10120-023-01393-2

المؤلفون: Goyal, L., Meric-Bernstam, F., Hollebecque, A., Valle, Juan W, Morizane, C., Karasic, T. B., Abrams, T. A., Furuse, J., Kelley, R. K., Cassier, P. A., Klümpen, H. J., Chang, H. M., Chen, L. T., Tabernero, J., Oh, D. Y., Mahipal, A., Moehler, M., Mitchell, E. P., Komatsu, Y., Masuda, K., Ahn, D., Epstein, R. S., Halim, A. B., Fu, Y., Salimi, T., Wacheck, V., He, Y., Liu, M., Benhadji, K. A., Bridgewater, J. A.

المساهمون: Department of Medicine, Stanford University School of Medicine, and the Stanford Cancer Center, Palo Alto and the University of California, San Francisco, San Francisco

Relation: https://dx.doi.org/10.1056/NEJMoa2206834; Goyal L, Meric-Bernstam F, Hollebecque A, Valle JW, Morizane C, Karasic TB, et al. Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma. The New England journal of medicine. 2023 Jan 19;388(3):228-39. PubMed PMID: 36652354. Epub 2023/01/19. eng.; http://hdl.handle.net/10541/626008; New England Journal of Medicine

الاتاحة: http://hdl.handle.net/10541/626008
https://doi.org/10.1056/NEJMoa2206834

المؤلفون: Benhadji, K., Li, Y., Wu, X., Liu, H., Xiao, X., Ding, Q., Xie, B., Sheng, C., Zheng, R., Yu, Q., Hu, X., Liu, X.S., Xiao, T.

المصدر: Annals of Oncology ; volume 34, page S187-S188 ; ISSN 0923-7534

الاتاحة: http://dx.doi.org/10.1016/j.annonc.2023.09.1506
https://api.elsevier.com/content/article/PII:S0923753423023438?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0923753423023438?httpAccept=text/plain

المؤلفون: Goyal, L., Meric-Bernstam, F., Hollebecque, A., Morizane, C., Valle, Juan W, Karasic, T. B., Abrams, T. A., Kelley, R. K., Cassier, P. A., Furuse, J., Klumpen, H. J., Chang, H. M., Chen, L. T., Komatsu, Y., Masuda, K., Ahn, D. H., Li, K., Benhadji, K. A., Wacheck, V., Bridgewater, J. A.

المساهمون: Mass General Cancer Center, Harvard Medical School, Boston, MA

Relation: https://dx.doi.org/10.1200/JCO.2022.40.16_suppl.4009; Goyal L, Meric-Bernstam F, Hollebecque A, Morizane C, Valle JW, Karasic TB, et al. Updated results of the FOENIX-CCA2 trial: Efficacy and safety of futibatinib in intrahepatic cholangiocarcinoma (iCCA) harboring FGFR2 fusions/rearrangements. Journal of Clinical Oncology. 2022 Jun;40(16). PubMed PMID: WOS:000863680301177.; http://hdl.handle.net/10541/625800; Journal of Clinical Oncology

الاتاحة: http://hdl.handle.net/10541/625800
https://doi.org/10.1200/JCO.2022.40.16_suppl.4009

المؤلفون: Bridgewater, JA, Hollebecque, A., Furuse, J, Goyal, L, Meric-Bernstam, F, Epstein, R. S., Morlock, R., Salimi, T., Wacheck, V., Liu, M, Benhadji, K., Valle, Juan W

المساهمون: UCL Cancer Institute, London, UK

Relation: https://dx.doi.org/10.1016/j.jval.2021.11.1065; Bridgewater, J A, Hollebecque, A, Furuse, J, Goyal, L, Meric-Bernstam, F, Epstein, R S, Morlock, R, Salimi, T, Wacheck, V, Liu, M, Benhadji, K, Valle, Juan W. "Patient-reported outcomes in futibatinib-treated intrahepatic cholangiocarcinoma patients with fgfr2 fusions/rearrangements: results from the foenix-CCA2 study. Value in Health . 2022; http://hdl.handle.net/10541/625198; Value in Health

الاتاحة: http://hdl.handle.net/10541/625198
https://doi.org/10.1016/j.jval.2021.11.1065

المؤلفون: Massard, C., Azaro, A., Soria, J. C., Lassen, U., Le Tourneau, C., Sarker, D., Smith, C., Ohnmacht, U., Oakley, G., Patel, B. K.R., Yuen, E. S.M., Benhadji, K. A., Rodon, J.

المصدر: Massard , C , Azaro , A , Soria , J C , Lassen , U , Le Tourneau , C , Sarker , D , Smith , C , Ohnmacht , U , Oakley , G , Patel , B K R , Yuen , E S M , Benhadji , K A & Rodon , J 2018 , ' First-in-human study of LY3039478, an oral Notch signaling inhibitor in advanced or metastatic cancer ' , Annals of Oncology , vol. 29 , no. 9 , pp. 1911-1917 . https://doi.org/10.1093/annonc/mdy244

مصطلحات موضوعية: colorectal cancer, LY3039478, metastatic cancer, Notch inhibition, Î 3-secretase inhibitors

وصف الملف: application/pdf

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/firstinhuman-study-of-ly3039478-an-oral-notch-signaling-inhibitor-in-advanced-or-metastatic-cancer(39a236e1-7714-4171-a2f7-9f72115cd40f).html
https://doi.org/10.1093/annonc/mdy244
https://kclpure.kcl.ac.uk/ws/files/111616223/First_in_human_study_MASSARD_Accepted_28_June_2018_GREEEN_AAM.pdf
https://kclpure.kcl.ac.uk/ws/files/111616225/Massard_et_al_Supplementary_Data_Mar_23.pdf
http://www.scopus.com/inward/record.url?scp=85053031701&partnerID=8YFLogxK

المؤلفون: Massard, C., Cassier, P. A., Azaro, A., Anderson, B., Yuen, E., Yu, D., Oakley, G., Benhadji, K. A., Pant, S.

المساهمون: Eli Lilly and Company

المصدر: Cancer Chemotherapy and Pharmacology ; volume 90, issue 4, page 335-344 ; ISSN 0344-5704 1432-0843

الاتاحة: http://dx.doi.org/10.1007/s00280-022-04461-z
https://link.springer.com/content/pdf/10.1007/s00280-022-04461-z.pdf
https://link.springer.com/article/10.1007/s00280-022-04461-z/fulltext.html

المؤلفون: Valle, Juan W, Hollebecque, A., Furuse, J., Goyal, L., Meric-Bernstam, F., Epstein, R. S., Salimi, T., Wacheck, V., Liu, M., Benhadji, K. A., Bridgewater, J. A.

المساهمون: University of Manchester, The Christie NHS Foundation Trust, Manchester

Relation: https://dx.doi.org/10.1200/JCO.2021.39.15_suppl.4097; Valle JW, Hollebecque A, Furuse J, Goyal L, Meric-Bernstam F, Epstein RS, et al. FOENIX-CCA2 quality of life data for futibatinib-treated intrahepatic cholangiocarcinoma (iCCA) patients with FGFR2 fusions/rearrangements. Vol. 39, Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2021. p. 4097–4097.; http://hdl.handle.net/10541/624867; Journal of Clinical Oncology

الاتاحة: http://hdl.handle.net/10541/624867
https://doi.org/10.1200/JCO.2021.39.15_suppl.4097

المؤلفون: Ghidini, M., Hochster, H. S., Doi, T., Van Cutsem, E., Makris, L., Benhadji, K. A., Mansoor, Was

المساهمون: Azienda Ospedaliera di Cremona, Cremona, Italy

Relation: https://dx.doi.org/10.1200/JCO.2021.39.3_suppl.476; Ghidini M, Hochster HS, Doi T, Van Cutsem E, Makris L, Benhadji KA, et al. Body weight loss (BWL) as a prognostic/predictive factor in previously treated patients (pts) with metastatic gastric or gastroesophageal junction cancer (mGC/GEJC): Post-hoc analyses of the phase III tags trial. JCO. 2021 Jan 20;39(3_suppl):476–476.; http://hdl.handle.net/10541/624003; Journal of Clinical Oncology

الاتاحة: http://hdl.handle.net/10541/624003
https://doi.org/10.1200/JCO.2021.39.3_suppl.476

المؤلفون: Furuse, J., Goyal, L., Meric-Bernstam, F., Hollebecque, A., Valle, Juan W, Morizane, C., Karasic, T. B., Abrams, T. A., Kelley, R. K., Cassier, P. A., Klumpen, H. J., Uboha, N., Mahipal, A., Mitchell, E., Ahn, E., Chang, H. M., Masuda, K., He, Y., Benhadji, K. A., Bridgewater, J. A.

المساهمون: Department of Medical Oncology, Kyorin University Hospital, Tokyo, Japan

Relation: https://dx.doi.org/10.1016/j.annonc.2020.10.137; Furuse J, Goyal L, Meric-Bernstam F, Hollebecque A, Valle JW, Morizane C, et al. 116MO Efficacy, safety, and quality of life (QoL) with futibatinib in patients (pts) with intrahepatic cholangiocarcinoma (iCCA) harboring FGFR2 fusions/rearrangements: FOENIX-CCA2. Annals of Oncology. 2020;31:S1288-S9.; http://hdl.handle.net/10541/623692; Annals of Oncology

الاتاحة: http://hdl.handle.net/10541/623692
https://doi.org/10.1016/j.annonc.2020.10.137

المؤلفون: Goyal, L., Meric-Bernstam, F., Hollebecque, A., Valle, Juan W, Morizane, C., Karasic, T. B., Furuse, J., He, Y. H., Soni, N., Benhadji, K. A., Bridgewater, J. A.

المساهمون: Massachusetts General Hospital, Boston, MA

Relation: Goyal L, Meric-Bernstam F, Hollebecque A, Valle JW, Morizane C, Karasic TB, et al. FOENIX-CCA2: A phase II, open-label, multicenter study of futibatinib in patients (pts) with intrahepatic cholangiocarcinoma (iCCA) harboring FGFR2 gene fusions or other rearrangements. Journal of Clinical Oncology. 2020;38(15); http://hdl.handle.net/10541/623383; Journal of Clinical Oncology

الاتاحة: http://hdl.handle.net/10541/623383

المؤلفون: Mansoor, Was, Arkenau, H. T., Alsina, M., Shitara, K., Thuss-Patience, P., Cuffe, S., Dvorkin, M., Park, D., Ando, T., Van Den Eynde, M., Beretta, G. D., Zaniboni, A., Doi, T., Tabernero, J., Ilson, D. H., Makris, L., Benhadji, K. A., Van Cutsem, E.

المساهمون: The Christie NHS Foundation Trust, Manchester, UK

Relation: https://dx.doi.org/10.1007/s10120-021-01156-x; Mansoor W, Arkenau HT, Alsina M, Shitara K, Thuss-Patience P, Cuffe S, et al. Trifluridine/tipiracil in patients with metastatic gastroesophageal junction cancer: a subgroup analysis from the phase 3 TAGS study. Gastric Cancer. 2021.; http://hdl.handle.net/10541/623937; Gastric Cancer

الاتاحة: http://hdl.handle.net/10541/623937
https://doi.org/10.1007/s10120-021-01156-x

المؤلفون: Goyal, L., Meric-Bernstam, F., Hollebecque, A., Valle, Juan W, Morizane, C., Karasic, T. B., Abrams, T. A., Furuse, J., Kelley, R. K., Cassier, P. A., Klümpen, H. J., Chang, H. M., Chen, L. T., Tabernero, J., Oh, D., Mahipal, A., Moehler, M., Komatsu, Y., Ahn, D. H., Epstein, R. S., Halim, A. B., Wacheck, V., He, Y. H., Liu, M., Benhadji, K. A., Bridgewater, J. A., Invest, F. C. S.

المساهمون: Division of Cancer Sciences, University of Manchester, Manchester, UK

Relation: Goyal L, Meric-Bernstam F, Hollebecque A, Valle JW, Morizane C, Karasic TB, et al. Plain language summary of the FOENIX-CCA2 study: futibatinib for people with advanced bile duct cancer. FUTURE ONCOLOGY. 2024 2024 JUN 17.; http://hdl.handle.net/10541/627084; Future Oncology

الاتاحة: http://hdl.handle.net/10541/627084
https://doi.org/10.1080/14796694.2024.2364504

المؤلفون: Benhadji, K A, Serova, M, Ghoul, A, Cvitkovic, E, Le Tourneau, C, Ogbourne, S M, Lokiec, F, Calvo, F, Hammel, P, Faivre, S, Raymond, E

المصدر: British Journal of Cancer ; volume 99, issue 11, page 1808-1815 ; ISSN 0007-0920 1532-1827

الاتاحة: http://dx.doi.org/10.1038/sj.bjc.6604642
http://www.nature.com/articles/6604642.pdf
http://www.nature.com/articles/6604642

المؤلفون: Serova, M, Galmarini, C M, Ghoul, A, Benhadji, K, Green, S R, Chiao, J, Faivre, S, Cvitkovic, E, Le Tourneau, C, Calvo, F, Raymond, E

المصدر: British Journal of Cancer ; volume 97, issue 5, page 628-636 ; ISSN 0007-0920 1532-1827

الاتاحة: http://dx.doi.org/10.1038/sj.bjc.6603896
http://www.nature.com/articles/6603896.pdf
http://www.nature.com/articles/6603896

المؤلفون: Tijeras-Raballand, A., Le Bitoux, M.A., Maillard, A., Albuquerque, M., Colnot, N., Barral, M., Dohan, A., Bonnin, P., Pocard, M., Benhadji, K., Paradis, V., Raymond, E., Harari, A., Faivre, S., De Gramont, A.

المصدر: European Journal of Cancer ; volume 69, page S133 ; ISSN 0959-8049

الاتاحة: http://dx.doi.org/10.1016/s0959-8049(16)32996-3
https://api.elsevier.com/content/article/PII:S0959804916329963?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0959804916329963?httpAccept=text/xml